AU2011338210B2 - Improved method and kit for determining severity and progression of periodontal disease - Google Patents

Improved method and kit for determining severity and progression of periodontal disease Download PDF

Info

Publication number
AU2011338210B2
AU2011338210B2 AU2011338210A AU2011338210A AU2011338210B2 AU 2011338210 B2 AU2011338210 B2 AU 2011338210B2 AU 2011338210 A AU2011338210 A AU 2011338210A AU 2011338210 A AU2011338210 A AU 2011338210A AU 2011338210 B2 AU2011338210 B2 AU 2011338210B2
Authority
AU
Australia
Prior art keywords
allele
illb
copies
patient
il1b
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2011338210A
Other languages
English (en)
Other versions
AU2011338210A1 (en
Inventor
Kenneth S. Kornman
John Rogus
Hwa-Ying Wang
Xiaodong Wu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Seaport Diagnostics Inc
Original Assignee
Orig3n Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orig3n Inc filed Critical Orig3n Inc
Publication of AU2011338210A1 publication Critical patent/AU2011338210A1/en
Priority to AU2016202211A priority Critical patent/AU2016202211B2/en
Application granted granted Critical
Publication of AU2011338210B2 publication Critical patent/AU2011338210B2/en
Assigned to ORIG3N, INC. reassignment ORIG3N, INC. Request for Assignment Assignors: INTERLEUKIN GENETICS, INC.
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6858Allele-specific amplification
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/172Haplotypes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/18Dental and oral disorders

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AU2011338210A 2010-12-09 2011-12-09 Improved method and kit for determining severity and progression of periodontal disease Ceased AU2011338210B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2016202211A AU2016202211B2 (en) 2010-12-09 2016-04-08 Improved Method and Kit for Determining Severity and Progression of Periodontal Disease

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US42162810P 2010-12-09 2010-12-09
US61/421,628 2010-12-09
US201161452157P 2011-03-13 2011-03-13
US61/452,157 2011-03-13
PCT/US2011/064216 WO2012079010A2 (en) 2010-12-09 2011-12-09 Improved method and kit for determining severity and progression of periodontal disease

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2016202211A Division AU2016202211B2 (en) 2010-12-09 2016-04-08 Improved Method and Kit for Determining Severity and Progression of Periodontal Disease

Publications (2)

Publication Number Publication Date
AU2011338210A1 AU2011338210A1 (en) 2013-07-25
AU2011338210B2 true AU2011338210B2 (en) 2016-05-12

Family

ID=46207769

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2011338210A Ceased AU2011338210B2 (en) 2010-12-09 2011-12-09 Improved method and kit for determining severity and progression of periodontal disease
AU2016202211A Ceased AU2016202211B2 (en) 2010-12-09 2016-04-08 Improved Method and Kit for Determining Severity and Progression of Periodontal Disease

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2016202211A Ceased AU2016202211B2 (en) 2010-12-09 2016-04-08 Improved Method and Kit for Determining Severity and Progression of Periodontal Disease

Country Status (10)

Country Link
US (3) US20120208187A1 (enExample)
EP (1) EP2649203B1 (enExample)
JP (2) JP6138692B2 (enExample)
CN (1) CN103547680B (enExample)
AU (2) AU2011338210B2 (enExample)
BR (1) BR112013014479B1 (enExample)
NZ (2) NZ701432A (enExample)
RU (2) RU2018122965A (enExample)
SG (1) SG191078A1 (enExample)
WO (1) WO2012079010A2 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106918706B (zh) * 2015-12-25 2019-05-21 广州瑞博奥生物科技有限公司 一种检测牙周病相关蛋白的抗体芯片试剂盒
CA3011363A1 (en) 2016-01-12 2017-07-20 Interleukin Genetics, Inc. Methods for predicting response to treatment
US10329620B2 (en) 2017-01-12 2019-06-25 Cardioforecast Ltd. Methods and kits for treating cardiovascular disease
GB201818627D0 (en) * 2018-11-15 2019-01-02 Mars Inc Analytical systems
JP7097855B2 (ja) * 2019-04-24 2022-07-08 ジェネシスヘルスケア株式会社 歯周病のリスクを判定する方法
CA3142662A1 (en) 2019-06-06 2020-12-10 Sitokine Limited Compositions and methods for treating lung, colorectal and breast cancer
WO2021028469A1 (en) 2019-08-12 2021-02-18 Sitokine Limited Compositions and methods for treating cytokine release syndrome and neurotoxicity
WO2021205013A1 (en) 2020-04-09 2021-10-14 Sitokine Limited Compositions and methods for treating covid-19
KR102571131B1 (ko) * 2021-06-01 2023-08-24 부산대학교 산학협력단 치주염 감별용 바이오마커 조성물, 치주염 중증도 감별용 바이오마커 조성물, 및 이를 이용한 진단 키트
EP4430621A1 (en) * 2021-11-12 2024-09-18 Mars, Incorporated Systems and methods for generating health reports based on veterinary oral care health test

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5110920A (en) 1982-01-22 1992-05-05 Cetus Corporation HLA typing method and DNA probes used therein
US4582788A (en) 1982-01-22 1986-04-15 Cetus Corporation HLA typing method and cDNA probes used therein
US4666828A (en) 1984-08-15 1987-05-19 The General Hospital Corporation Test for Huntington's disease
US4801531A (en) 1985-04-17 1989-01-31 Biotechnology Research Partners, Ltd. Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
US5268267A (en) 1987-08-21 1993-12-07 The General Hospital Corporation Method for diagnosing small cell carcinoma
US5272057A (en) 1988-10-14 1993-12-21 Georgetown University Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
US5328829A (en) 1990-07-05 1994-07-12 Forsyth Dental Infirmary For Children Method of determining sites of active periodontal disease
US5686246A (en) * 1995-08-03 1997-11-11 Kornman; Kenneth S. Detecting genetic predisposition to periodontal disease
GB9711040D0 (en) * 1997-05-29 1997-07-23 Duff Gordon W Prediction of inflammatory disease
US20050282198A1 (en) * 1997-05-29 2005-12-22 Interleukin Genetics, Inc. Diagnostics and therapeutics for diseases associated with an IL-1 inflammatory haplotype
US6130042A (en) * 1998-03-05 2000-10-10 The United States Of America As Represented By The Department Of Health And Human Services Compositions and methods for diagnosing periodontal disease
ES2356167T3 (es) * 2004-05-03 2011-04-05 Interleukin Genetics, Inc. Método de diagnóstico y terapia para enfermedades asociadas con un haplotipo inflamatorio il-1.
US20080118920A1 (en) * 2004-05-03 2008-05-22 Duff Gordon W Diagnostics And Therapeutics For Diseases Associated With An Il-1 Inflammatory Haplotype
EP2304052A2 (en) * 2008-05-02 2011-04-06 Interleukin Genetics, Inc. Detecting genetic predisposition to osteoarthritis associated conditions

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEN, H. et al., Human Molecular Genetics, 2006, Vol. 15, pages 519-529 *
ROGUS, J. et al., Human Genetics, 2008, Vol. 123, pages 387-398 *

Also Published As

Publication number Publication date
JP6138692B2 (ja) 2017-05-31
JP2017121237A (ja) 2017-07-13
JP6622731B2 (ja) 2019-12-18
EP2649203A2 (en) 2013-10-16
AU2016202211B2 (en) 2017-02-23
EP2649203A4 (en) 2014-05-07
CN103547680A (zh) 2014-01-29
AU2016202211A1 (en) 2016-05-05
AU2011338210A1 (en) 2013-07-25
WO2012079010A2 (en) 2012-06-14
RU2018122965A3 (enExample) 2019-04-11
BR112013014479A2 (pt) 2016-09-20
JP2013544536A (ja) 2013-12-19
RU2013131239A (ru) 2015-01-20
US20120208187A1 (en) 2012-08-16
RU2018122965A (ru) 2019-03-06
RU2664431C2 (ru) 2018-08-17
CN103547680B (zh) 2017-05-24
NZ701432A (en) 2016-06-24
BR112013014479B1 (pt) 2020-10-27
US20160244841A1 (en) 2016-08-25
SG191078A1 (en) 2013-07-31
EP2649203B1 (en) 2019-07-24
US9347090B2 (en) 2016-05-24
WO2012079010A3 (en) 2012-08-23
NZ612799A (en) 2015-04-24
US20130337448A1 (en) 2013-12-19

Similar Documents

Publication Publication Date Title
AU2011338210B2 (en) Improved method and kit for determining severity and progression of periodontal disease
AU755107B2 (en) Prediction of inflammatory disease associated with IL-1 geneloci polymorphisms
JP5762282B2 (ja) 変形性関節症に関連する状態に対する遺伝的素因の検出
CA2723247A1 (en) Detecting genetic predisposition to osteoarthritis associated conditions
US20100092959A1 (en) Single nucleotide polymorphisms as genetic markers for childhood leukemia
Jirapongsananuruk et al. CYBB mutation analysis in X-linked chronic granulomatous disease
US20050244830A1 (en) Quantitative multiplex amplification on a genomic scale, and applications for detecting genomic rearrangements
HK1188260B (en) Improved method for determining severity and progression of periodontal disease
HK1188260A (en) Improved method for determining severity and progression of periodontal disease
JP6892102B2 (ja) ウシ白血病ウイルス(blv)プロウイルスロードの判定方法およびその利用
WO2002090585A2 (en) Genetic polymorphism pattern of tgfb1 as marker for susceptability to renal disease
US7771942B2 (en) Genetic marker for prostate cancer
Chai et al. Genetic polymorphisms and periodontitis
WO2011147763A1 (en) Biomarkers
AU2015202038A1 (en) Detecting Genetic Predisposition To Osteoarthritis Associated Conditions

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
PC Assignment registered

Owner name: ORIG3N, INC.

Free format text: FORMER OWNER(S): INTERLEUKIN GENETICS, INC.

MK14 Patent ceased section 143(a) (annual fees not paid) or expired