JP2014221905A5 - - Google Patents
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- Publication number
- JP2014221905A5 JP2014221905A5 JP2014142045A JP2014142045A JP2014221905A5 JP 2014221905 A5 JP2014221905 A5 JP 2014221905A5 JP 2014142045 A JP2014142045 A JP 2014142045A JP 2014142045 A JP2014142045 A JP 2014142045A JP 2014221905 A5 JP2014221905 A5 JP 2014221905A5
- Authority
- JP
- Japan
- Prior art keywords
- oligomer
- ultrafiltration
- chito
- deacetylation
- partially deacetylated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920002101 Chitin Polymers 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 10
- 102000012286 Chitinases Human genes 0.000 claims description 6
- 108010022172 Chitinases Proteins 0.000 claims description 6
- 230000006196 deacetylation Effects 0.000 claims description 6
- 238000003381 deacetylation reaction Methods 0.000 claims description 6
- -1 flakes Substances 0.000 claims description 2
- 238000000108 ultra-filtration Methods 0.000 claims 4
- 230000002378 acidificating effect Effects 0.000 claims 1
- 230000000850 deacetylating effect Effects 0.000 claims 1
- 239000000539 dimer Substances 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- 239000002657 fibrous material Substances 0.000 claims 1
- 230000003301 hydrolyzing effect Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 239000000178 monomer Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 239000012465 retentate Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 description 18
- 230000007062 hydrolysis Effects 0.000 description 5
- 238000006460 hydrolysis reaction Methods 0.000 description 5
- 238000005457 optimization Methods 0.000 description 5
- 229920000642 polymer Polymers 0.000 description 5
- 230000001225 therapeutic effect Effects 0.000 description 5
- 229920001661 Chitosan Polymers 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- 239000007943 implant Substances 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 238000011065 in-situ storage Methods 0.000 description 2
- 239000002244 precipitate Substances 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000012384 transportation and delivery Methods 0.000 description 2
- 239000003929 acidic solution Substances 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000000845 cartilage Anatomy 0.000 description 1
- 210000003321 cartilage cell Anatomy 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 230000003196 chaotropic effect Effects 0.000 description 1
- 239000000356 contaminant Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000002158 endotoxin Substances 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 229920000140 heteropolymer Polymers 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 238000007918 intramuscular administration Methods 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 210000002540 macrophage Anatomy 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 230000003472 neutralizing effect Effects 0.000 description 1
- 210000004663 osteoprogenitor cell Anatomy 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 230000001376 precipitating effect Effects 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 238000007873 sieving Methods 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 238000007910 systemic administration Methods 0.000 description 1
- 238000012385 systemic delivery Methods 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IS7895 | 2005-06-14 | ||
| IS7895 | 2005-06-14 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008516507A Division JP5632125B2 (ja) | 2005-06-14 | 2006-06-14 | 部分的脱アセチル化キチン誘導体の組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014221905A JP2014221905A (ja) | 2014-11-27 |
| JP2014221905A5 true JP2014221905A5 (enExample) | 2018-01-18 |
| JP6293005B2 JP6293005B2 (ja) | 2018-03-14 |
Family
ID=36685789
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008516507A Active JP5632125B2 (ja) | 2005-06-14 | 2006-06-14 | 部分的脱アセチル化キチン誘導体の組成物 |
| JP2014142045A Active JP6293005B2 (ja) | 2005-06-14 | 2014-07-10 | 部分的脱アセチル化キチン誘導体の組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008516507A Active JP5632125B2 (ja) | 2005-06-14 | 2006-06-14 | 部分的脱アセチル化キチン誘導体の組成物 |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US9078949B2 (enExample) |
| EP (1) | EP1917218B1 (enExample) |
| JP (2) | JP5632125B2 (enExample) |
| KR (1) | KR101569751B1 (enExample) |
| CN (1) | CN101248019B (enExample) |
| AU (1) | AU2006257177A1 (enExample) |
| BR (1) | BRPI0612034A2 (enExample) |
| CA (1) | CA2611453C (enExample) |
| DK (1) | DK1917218T3 (enExample) |
| HU (1) | HUE035956T2 (enExample) |
| LT (1) | LT1917218T (enExample) |
| MX (2) | MX375577B (enExample) |
| NO (2) | NO344086B1 (enExample) |
| NZ (1) | NZ565022A (enExample) |
| RU (1) | RU2421467C2 (enExample) |
| SI (1) | SI1917218T1 (enExample) |
| WO (1) | WO2006134614A1 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IS6085A (is) | 2001-09-26 | 2003-03-27 | Genis Ehf. | Lyfjablanda með kítósan óligómerum |
| US9034348B2 (en) | 2006-12-11 | 2015-05-19 | Chi2Gel Ltd. | Injectable chitosan mixtures forming hydrogels |
| EP1958639A1 (en) | 2007-02-14 | 2008-08-20 | Polichem S.A. | Use of chitosans for the treatment of nail inflammatory diseases |
| US10201490B2 (en) | 2007-02-14 | 2019-02-12 | Polichem Sa | Use of chitosans for the treatment of nail inflammatory diseases |
| JP5746617B2 (ja) * | 2008-06-11 | 2015-07-08 | チ２ジェル リミテッドＣｈｉ２Ｇｅｌ Ｌｔｄ． | キトサン混合物を形成する注入可能なヒドロゲル |
| WO2010007631A1 (en) * | 2008-07-18 | 2010-01-21 | Genis Ehf. | New composition for treating autoimmune disorders |
| CN102417550B (zh) * | 2010-09-28 | 2014-04-30 | 扬州鸿信生物制品有限公司 | 一种甲壳素生产设备 |
| WO2012145626A1 (en) * | 2011-04-22 | 2012-10-26 | Ancora Pharmaceuticals Inc. | Synthetic oligosaccharides for staphylococcus vaccine |
| US10130654B2 (en) * | 2011-05-24 | 2018-11-20 | Hangli Biosciences Co., Ltd. | Method of inducing osteogensis and promoting osseointegration around an implant |
| GB201205174D0 (en) * | 2012-03-23 | 2012-05-09 | Medtrade Products Ltd | Process for producing low endotoxin chitosan |
| CN104470550A (zh) * | 2012-04-23 | 2015-03-25 | 杰尼斯公共有限公司 | 作为骨移植替代物的含有部分脱乙酰壳多糖的自硬化生物活性接合剂组合物 |
| US20160017062A1 (en) | 2013-03-12 | 2016-01-21 | Wellstat Vaccines, Llc | Antibodies targeted to fungal cell wall polysaccharides |
| GB201309606D0 (en) * | 2013-05-29 | 2013-07-10 | Medtrade Products Ltd | Process for producing low endotoxin chitosan |
| GB201309607D0 (en) * | 2013-05-29 | 2013-07-10 | Medtrade Products Ltd | Process for producing low endotoxin chitosan |
| GB2514592A (en) | 2013-05-30 | 2014-12-03 | Medtrade Products Ltd | Degradable haemostat composition |
| FR3016882A1 (fr) | 2014-01-30 | 2015-07-31 | Sofradim Production | Procede de preparation de chitosane a haut degre d’acetylation |
| JP6512630B2 (ja) * | 2015-02-26 | 2019-05-15 | オルガノ株式会社 | セレン及び／またはヒ素の濃縮方法及び分析方法並びに装置 |
| CN108114321A (zh) * | 2017-12-29 | 2018-06-05 | 广州军区广州总医院 | 一种抗骨巨细胞瘤壳聚糖-纳米羟基磷灰石支架、其制备方法及应用 |
| CN109529105A (zh) * | 2018-10-04 | 2019-03-29 | 南京航空航天大学溧水仿生产业研究院有限公司 | 仿生人工骨材料的制备方法 |
| WO2020186021A1 (en) * | 2019-03-13 | 2020-09-17 | Virginia Commonwealth University | Method for forming flexible and biodegradable structures from low molecular weight chitin biopolymers |
| WO2021195452A1 (en) * | 2020-03-26 | 2021-09-30 | Subhra Mohapatra | Use of oligochitosans and derivatives thereof for neutralizing viral agents |
| JP7602224B2 (ja) * | 2020-05-15 | 2024-12-18 | 京都府公立大学法人 | 非晶性キチンを含む創傷治癒材 |
| CN111803714B (zh) * | 2020-07-29 | 2021-12-21 | 陕西科技大学 | 一种综合酸-碱溶剂体系的壳聚糖骨修复支架及其制备方法 |
| CN112341551A (zh) * | 2020-11-05 | 2021-02-09 | 广东广纳安疗科技有限公司 | 一种具有超低内毒素的壳聚糖类物质及其制备方法 |
| CN112724273B (zh) * | 2021-01-26 | 2022-02-22 | 焦点生物医药有限公司 | 一种高分子量银耳多糖的提取及制备方法 |
| EP4122961A1 (en) * | 2021-07-20 | 2023-01-25 | Westfälische Wilhelms-Universität Münster | Chitosan oligomers and uses thereof |
| KR20240122463A (ko) * | 2021-12-20 | 2024-08-12 | 제니스 에이치에프 | 부분 탈아세틸화 키토산을 포함하는 생활성 코팅을 갖는 임플란트 |
| CN114533967B (zh) * | 2022-03-30 | 2023-01-03 | 江苏益通生物科技有限公司 | 一种脱乙酰壳聚糖神经导管及其制备方法 |
| JP2025526752A (ja) * | 2022-08-11 | 2025-08-15 | ジーニス エイチエフ． | ３ｄプリントされた生体活性スキャホールド |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2795579A (en) * | 1953-10-09 | 1957-06-11 | Warner Lambert Pharmaceutical | Process for purification of chitosan by means of the salicylic acid salt thereof |
| DK602489A (da) * | 1988-11-30 | 1990-05-31 | Rhone Poulenc Sante | Praeparater til overtraekning af foder til droevtyggere |
| JP2814701B2 (ja) * | 1990-06-04 | 1998-10-27 | 味の素株式会社 | 水容性部分脱アセチル化キチンの製造法 |
| JP3181337B2 (ja) * | 1991-09-13 | 2001-07-03 | ピアス株式会社 | キトサンオリゴ糖混合物の製造方法、及びキチンオリゴ糖混合物の製造方法 |
| RU2065447C1 (ru) * | 1992-11-30 | 1996-08-20 | Владимир Петрович Голицин | Способ получения хитозана |
| KR970008132B1 (ko) | 1993-02-08 | 1997-05-21 | 전동원 | 생체 임상의학용 키틴 및 키토산 제조방법 |
| JP3118423B2 (ja) * | 1996-08-30 | 2000-12-18 | ツヤック株式会社 | 水溶性の部分アセチル化キトサン液の製造方法 |
| JP2990248B2 (ja) * | 1997-06-18 | 1999-12-13 | 鳥取県 | 非晶質の水溶性部分脱アセチル化キチンの製造方法 |
| JPH11276189A (ja) * | 1998-03-30 | 1999-10-12 | Tottori Prefecture | 非晶質の水溶性部分脱アセチル化キチンを基質とする酵素によるオリゴ糖の製造方法 |
| US20030158302A1 (en) * | 1999-12-09 | 2003-08-21 | Cyric Chaput | Mineral-polymer hybrid composition |
| JP3653626B2 (ja) * | 2000-01-13 | 2005-06-02 | 独立行政法人科学技術振興機構 | 有機・無機交互多重積層複合体 |
| JP4669932B2 (ja) * | 2000-05-02 | 2011-04-13 | 学校法人日本大学 | 生体材料用組成物及びその硬化体 |
| WO2002059395A2 (en) * | 2000-12-28 | 2002-08-01 | The Board Of Regents Of The University Of Nebraska | Electrolytic deposition of coatings for prosthetic metals and alloys |
| NO20015986D0 (no) * | 2001-08-02 | 2001-12-06 | Einar J Mustaparta | Produktet chitosan, samt fremstillingsmetode og anvendelse av chitosan |
| IS6085A (is) * | 2001-09-26 | 2003-03-27 | Genis Ehf. | Lyfjablanda með kítósan óligómerum |
| JP3755004B2 (ja) * | 2003-07-01 | 2006-03-15 | 独立行政法人物質・材料研究機構 | キチン誘導体−リン酸カルシウム複合体繊維とその製造方法 |
| CN1233664C (zh) * | 2003-12-23 | 2005-12-28 | 孝感学院 | 一种制备水溶性壳聚糖的方法 |
| DE202008005046U1 (de) | 2008-04-11 | 2008-07-03 | Design Ballendat Gmbh | Tisch mit verschwenkbarem Bügelfuß |
-
2006
- 2006-06-14 JP JP2008516507A patent/JP5632125B2/ja active Active
- 2006-06-14 AU AU2006257177A patent/AU2006257177A1/en not_active Abandoned
- 2006-06-14 DK DK06745229.2T patent/DK1917218T3/en active
- 2006-06-14 BR BRPI0612034-2A patent/BRPI0612034A2/pt not_active Application Discontinuation
- 2006-06-14 LT LTEP06745229.2T patent/LT1917218T/lt unknown
- 2006-06-14 CA CA2611453A patent/CA2611453C/en active Active
- 2006-06-14 CN CN2006800285048A patent/CN101248019B/zh active Active
- 2006-06-14 MX MX2015012065A patent/MX375577B/es unknown
- 2006-06-14 EP EP06745229.2A patent/EP1917218B1/en active Active
- 2006-06-14 NZ NZ565022A patent/NZ565022A/en unknown
- 2006-06-14 HU HUE06745229A patent/HUE035956T2/en unknown
- 2006-06-14 KR KR1020087001087A patent/KR101569751B1/ko active Active
- 2006-06-14 RU RU2008101385/05A patent/RU2421467C2/ru active
- 2006-06-14 MX MX2007015767A patent/MX336736B/es unknown
- 2006-06-14 SI SI200632196T patent/SI1917218T1/sl unknown
- 2006-06-14 US US11/922,014 patent/US9078949B2/en active Active
- 2006-06-14 WO PCT/IS2006/000013 patent/WO2006134614A1/en not_active Ceased
-
2008
- 2008-01-14 NO NO20080240A patent/NO344086B1/no unknown
-
2014
- 2014-07-10 JP JP2014142045A patent/JP6293005B2/ja active Active
-
2015
- 2015-06-11 US US14/736,984 patent/US20160002360A1/en not_active Abandoned
-
2017
- 2017-12-27 US US15/855,884 patent/US20180186899A1/en not_active Abandoned
-
2019
- 2019-07-30 NO NO20190933A patent/NO20190933A1/no not_active Application Discontinuation
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