|
US4738681A
(en)
*
|
1985-07-10 |
1988-04-19 |
Harrington Arthritis Research Center |
Femoral-joint prosthetic device
|
|
US5605690A
(en)
*
|
1989-09-05 |
1997-02-25 |
Immunex Corporation |
Methods of lowering active TNF-α levels in mammals using tumor necrosis factor receptor
|
|
US5370870A
(en)
*
|
1989-10-06 |
1994-12-06 |
Genentech, Inc. |
Method for protection against reactive oxygen species
|
|
SE500903C2
(sv)
|
1989-12-20 |
1994-09-26 |
Atlas Copco Constr & Mining |
Bergborrningsrigg
|
|
US6075181A
(en)
*
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5364839A
(en)
|
1990-06-18 |
1994-11-15 |
Genetics Institute, Inc. |
Osteoinductive pharmaceutical formulations
|
|
US5206023A
(en)
|
1991-01-31 |
1993-04-27 |
Robert F. Shaw |
Method and compositions for the treatment and repair of defects or lesions in cartilage
|
|
US5273033A
(en)
*
|
1991-09-19 |
1993-12-28 |
Murray Electronics Associates Limited Partnership |
Electrical stimulation for treatment of osteoarthritis
|
|
US5716805A
(en)
*
|
1991-10-25 |
1998-02-10 |
Immunex Corporation |
Methods of preparing soluble, oligomeric proteins
|
|
AU4231393A
(en)
*
|
1992-05-08 |
1993-12-13 |
Genentech Inc. |
Antibodies to leukemia inhibitory factor
|
|
GB9214857D0
(en)
|
1992-07-13 |
1992-08-26 |
Medical Res Council |
Human nucleic acid fragments and their use
|
|
US5536637A
(en)
*
|
1993-04-07 |
1996-07-16 |
Genetics Institute, Inc. |
Method of screening for cDNA encoding novel secreted mammalian proteins in yeast
|
|
US6562333B1
(en)
|
1993-06-14 |
2003-05-13 |
Schering Corporation |
Purified mammalian CTLA-8 antigens and related reagents
|
|
US6274711B1
(en)
|
1993-06-14 |
2001-08-14 |
Inserm, Institut National De La Sante Et De La Recherche Medicale |
Purified mammalian CTLA-8 antigens and related reagents
|
|
US5830877A
(en)
|
1993-08-26 |
1998-11-03 |
The Regents Of The University Of California |
Method, compositions and devices for administration of naked polynucleotides which encode antigens and immunostimulatory
|
|
US5444047A
(en)
*
|
1994-06-16 |
1995-08-22 |
Dipasquale; Gene |
Treatment of arthritic and post-surgical orthopedic conditions with Insulin-like Growth Factor-I
|
|
WO2000073452A2
(en)
|
1999-06-02 |
2000-12-07 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
|
NZ306653A
(en)
|
1995-03-23 |
1999-03-29 |
Immunex Corp |
Isolated dna il-17 receptors
|
|
US5573762A
(en)
*
|
1995-04-24 |
1996-11-12 |
Genentech, Inc. |
Use of leukemia inhibitory factor specific antibodies and endothelin antagonists for treatment of cardiac hypertrophy
|
|
DE69634726T2
(de)
|
1995-07-19 |
2006-05-04 |
Genetics Institute, LLC, Cambridge |
Menschliche ctla-8 und verwendung von ctla-8 ähnlichen proteinen
|
|
US6902735B1
(en)
|
1995-07-19 |
2005-06-07 |
Genetics Institute, Llc |
Antibodies to human IL-17F and other CTLA-8-related proteins
|
|
US5707829A
(en)
|
1995-08-11 |
1998-01-13 |
Genetics Institute, Inc. |
DNA sequences and secreted proteins encoded thereby
|
|
US6074849A
(en)
*
|
1995-07-19 |
2000-06-13 |
Genetics Institute, Inc. |
Polynucleotides encoding human CTLA-8 related proteins
|
|
AU1407997A
(en)
|
1995-12-01 |
1997-06-19 |
Beth Israel Hospital |
Il-12 p40 subunit fusion polypeptides and uses thereof
|
|
EP1876241A3
(en)
|
1996-01-11 |
2008-07-30 |
Corixa Corporation |
Compositions and methods for the treatment and diagnosis of breast cancer
|
|
WO2002008284A2
(en)
|
2000-07-20 |
2002-01-31 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
|
|
WO2002000690A2
(en)
|
2000-06-23 |
2002-01-03 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
|
|
WO1998023284A1
(en)
|
1996-11-27 |
1998-06-04 |
Immunex Corporation |
Method of regulating nitric oxide production
|
|
US6054559A
(en)
*
|
1997-01-28 |
2000-04-25 |
Smithkline Beecham Corporation |
Interleukin-1 receptor antagonist beta (IL-1raβ)
|
|
WO2001018022A1
(en)
|
1999-09-03 |
2001-03-15 |
Human Genome Sciences, Inc. |
52 human secreted proteins
|
|
US6579520B2
(en)
*
|
1998-05-15 |
2003-06-17 |
Genentech, Inc. |
IL-17 related mammalian cytokine polypeptides (IL-17E)
|
|
US20020177188A1
(en)
*
|
1998-05-15 |
2002-11-28 |
Genentech, Inc. |
IL-17 homologous polypeptides and therapeutic uses thereof
|
|
WO2000053752A2
(en)
|
1999-03-08 |
2000-09-14 |
Genentech, Inc. |
Promotion or inhibition of angiogenesis and cardiovascularization
|
|
US6569645B2
(en)
*
|
1999-05-14 |
2003-05-27 |
Genentech, Inc. |
IL-17 homologous polypeptides and therapeutic uses thereof
|
|
KR20010012111A
(ko)
|
1997-04-25 |
2001-02-15 |
리스 데브라 케이. |
포유동물의 사이토킨-유사 인자 7
|
|
JP2001510035A
(ja)
|
1997-07-16 |
2001-07-31 |
ヒューマン ジノーム サイエンシーズ, インコーポレイテッド |
インターロイキン−20
|
|
ZA986596B
(en)
|
1997-07-25 |
1999-02-08 |
Schering Corp |
Mammalian cytokine related reagents
|
|
US6060284A
(en)
*
|
1997-07-25 |
2000-05-09 |
Schering Corporation |
DNA encoding interleukin-B30
|
|
ES2333385T3
(es)
|
1997-09-17 |
2010-02-19 |
Human Genome Sciences, Inc. |
Proteina del tipo de interleuquina-17.
|
|
US6482923B1
(en)
|
1997-09-17 |
2002-11-19 |
Human Genome Sciences, Inc. |
Interleukin 17-like receptor protein
|
|
US6562578B1
(en)
*
|
1999-01-11 |
2003-05-13 |
Schering Corporation |
IL-17-like cytokine binding compounds and antibodies
|
|
AU2004799A
(en)
|
1997-12-19 |
1999-07-12 |
Millennium Biotherapeutics, Inc. |
Novel embryo-derived interleukin related factor molecules and uses therefor
|
|
JP2002533055A
(ja)
|
1997-12-19 |
2002-10-08 |
ワイス |
軟骨の変性疾患のためのトランスジェニック動物モデル
|
|
AU2031399A
(en)
|
1998-01-09 |
1999-07-26 |
Immunex Corporation |
Human and murine il-17d, cytokine related to interleukin-17: dna and polypeptides
|
|
ES2312205T3
(es)
|
1998-03-10 |
2009-02-16 |
Genentech, Inc. |
Nuevo polipeptido y acidos nucleicos que lo codifican.
|
|
ES2263865T3
(es)
|
1998-03-25 |
2006-12-16 |
Genentech, Inc. |
Homologo humano de neurotrimina.
|
|
AU760549B2
(en)
|
1998-04-03 |
2003-05-15 |
University Of Iowa Research Foundation, The |
Methods and products for stimulating the immune system using immunotherapeutic oligonucleotides and cytokines
|
|
DE69942607D1
(de)
*
|
1998-04-14 |
2010-09-02 |
Chugai Pharmaceutical Co Ltd |
Neues cytokinartiges protein
|
|
US20050147609A1
(en)
|
1998-05-15 |
2005-07-07 |
Genentech, Inc. |
Use of anti-IL-17 antibody for the treatment of cartilage damaged by osteoarthritis
|
|
AU740405B2
(en)
*
|
1998-05-15 |
2001-11-01 |
Genentech Inc. |
IL-17 homologous polypeptides and therapeutic uses thereof
|
|
US7771719B1
(en)
*
|
2000-01-11 |
2010-08-10 |
Genentech, Inc. |
Pharmaceutical compositions, kits, and therapeutic uses of antagonist antibodies to IL-17E
|
|
US20010023070A1
(en)
|
1998-05-29 |
2001-09-20 |
Reinhard Ebner |
Interleukins-21 and 22
|
|
EP1443055A3
(en)
|
1998-05-29 |
2005-06-08 |
Human Genome Sciences, Inc. |
Interleukins-21 and 22
|
|
EP1082433A4
(en)
*
|
1998-05-29 |
2003-01-02 |
Human Genome Sciences Inc |
Interleukins 21 and 22
|
|
DK1114156T3
(da)
|
1998-09-17 |
2008-03-03 |
Zymogenetics Inc |
Transformerende vækstfaktor Beta-9 (ZTGFSS9) fra pattedyr
|
|
AU6277799A
(en)
|
1998-10-02 |
2000-04-26 |
Eli Lilly And Company |
Il-17 homolog nucleic acids, polypeptides, vectors, host cells, methods and usesthereof
|
|
JP2000186046A
(ja)
|
1998-10-14 |
2000-07-04 |
Snow Brand Milk Prod Co Ltd |
慢性関節リウマチ治療剤及び診断方法
|
|
WO2001054477A2
(en)
|
2000-01-25 |
2001-08-02 |
Hyseq, Inc. |
Novel nucleic acids and polypeptides
|
|
EP2341144A1
(en)
|
1999-01-11 |
2011-07-06 |
Schering Corporation |
Interleukin-17 related mammalian cytokines. Polynucleotides encoding them. Uses
|
|
WO2000042187A1
(en)
|
1999-01-11 |
2000-07-20 |
Schering Corporation |
Interleukin-17 related mammalian cytokine (il-171). polynucleotides encoding them. uses
|
|
HUP0200575A3
(en)
|
1999-03-25 |
2004-11-29 |
Abbott Gmbh & Co Kg |
Human antibodies that bind human il-12 and methods for producing
|
|
US6914128B1
(en)
*
|
1999-03-25 |
2005-07-05 |
Abbott Gmbh & Co. Kg |
Human antibodies that bind human IL-12 and methods for producing
|
|
AU3632600A
(en)
|
1999-05-14 |
2000-12-05 |
Genentech Inc. |
Compositions and methods for the treatment of immune related diseases
|
|
US20030082734A1
(en)
*
|
1999-06-01 |
2003-05-01 |
Dowling Lynette M. |
Mammalian receptor proteins; related reagents and methods
|
|
EP2241623A3
(en)
|
1999-07-07 |
2010-12-01 |
ZymoGenetics, Inc. |
Monoclonal antibody against a human cytokine receptor
|
|
US20030199041A1
(en)
*
|
1999-07-07 |
2003-10-23 |
Presnell Scott R. |
Interleukin-17 receptor homologue
|
|
EP1248798A2
(en)
|
1999-08-18 |
2002-10-16 |
Fraunhofer-Gesellschaft Zur Förderung Der Angewandten Forschung E.V. |
Human dna sequences
|
|
CA2380355A1
(en)
|
1999-09-01 |
2001-03-08 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
AU7445900A
(en)
*
|
1999-09-27 |
2001-04-30 |
Chugai Seiyaku Kabushiki Kaisha |
Novel hemopoietin receptor protein, nr12
|
|
CA2390786A1
(en)
|
1999-11-30 |
2001-06-07 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
|
ES2380812T3
(es)
|
1999-12-23 |
2012-05-18 |
Genentech, Inc. |
Polipéptidos homólogos a IL-17 y usos terapéuticos de los mismos
|
|
US6380362B1
(en)
|
1999-12-23 |
2002-04-30 |
Genesis Research & Development Corporation Ltd. |
Polynucleotides, polypeptides expressed by the polynucleotides and methods for their use
|
|
US20040043397A1
(en)
*
|
2000-01-11 |
2004-03-04 |
Genentech, Inc. |
IL-17 homologous polypeptides and therapeutic uses thereof
|
|
US20040034192A1
(en)
|
2000-01-06 |
2004-02-19 |
Seishi Kato |
Human proteins having hyprophobic domains and dnas encoding these proteins
|
|
AU2001236638A1
(en)
|
2000-02-04 |
2001-08-14 |
The Board Of Trustees Of The University Of Arkansas |
Evi27 gene sequences and protein encoded thereby
|
|
AU6802801A
(en)
|
2000-03-01 |
2001-09-24 |
Genentech Inc |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
TWI322154B
(en)
|
2000-03-16 |
2010-03-21 |
Amgen Inc |
Il-17 receptor like molecules and uses thereof
|
|
EP1266002A2
(en)
|
2000-03-16 |
2002-12-18 |
Amgen Inc., |
Il-17 receptor like molecules and uses thereof
|
|
US7094566B2
(en)
*
|
2000-03-16 |
2006-08-22 |
Amgen Inc., |
IL-17 receptor like molecules and uses thereof
|
|
DE60120372T2
(de)
*
|
2000-03-24 |
2007-07-05 |
Genentech Inc., San Francisco |
Verwendung von insulin zur behandlung von knorpelkrankheiten
|
|
US6479636B1
(en)
|
2000-04-11 |
2002-11-12 |
Honiron Corporation (A Louisiana Corporation) |
Sugarcane fractioning system
|
|
DE60136921D1
(de)
|
2000-04-18 |
2009-01-22 |
Schering Corp |
Medizinische Verwendung von IL-174 Agonisten und Antagonisten
|
|
US6756481B2
(en)
|
2000-05-10 |
2004-06-29 |
Schering Corporation |
IL-23 receptor binding compositions
|
|
US7422743B2
(en)
*
|
2000-05-10 |
2008-09-09 |
Schering Corporation |
Mammalian receptor protein DCRS5;methods of treatment
|
|
US20030092881A1
(en)
|
2000-05-24 |
2003-05-15 |
Gorman Daniel M. |
Mammalian receptor proteins; related reagents and methods
|
|
US20030096969A1
(en)
*
|
2000-06-02 |
2003-05-22 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
AU6531101A
(en)
|
2000-06-02 |
2001-12-17 |
Genentech Inc |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
AU2001272968C1
(en)
|
2000-06-22 |
2008-06-05 |
Amgen Inc. |
Il-17 molecules and uses thereof
|
|
AU2001273150A1
(en)
|
2000-07-20 |
2002-02-05 |
Genentech Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
WO2002008259A2
(en)
|
2000-07-26 |
2002-01-31 |
Zymogenetics, Inc. |
Human cytokine receptor
|
|
US6902734B2
(en)
*
|
2000-08-07 |
2005-06-07 |
Centocor, Inc. |
Anti-IL-12 antibodies and compositions thereof
|
|
JP2002139499A
(ja)
*
|
2000-08-23 |
2002-05-17 |
Sanyo Electric Co Ltd |
化学物質センサおよび化学物質の検出方法
|
|
JP2002076897A
(ja)
*
|
2000-08-29 |
2002-03-15 |
Toshiba Corp |
Daコンバータ
|
|
DE60125563T2
(de)
|
2000-10-13 |
2007-10-04 |
Eli Lilly And Co., Indianapolis |
Verfahren zur verwendung eines humanen il-17 verwandten polypeptids zur behandlung von krankheiten
|
|
GB2372464B
(en)
|
2001-02-22 |
2003-05-14 |
Vivascience Ltd |
Method of isolating a charged compound
|
|
US20070160576A1
(en)
|
2001-06-05 |
2007-07-12 |
Genentech, Inc. |
IL-17A/F heterologous polypeptides and therapeutic uses thereof
|
|
US20030049255A1
(en)
*
|
2001-08-07 |
2003-03-13 |
Sims John E. |
Interleukin-1 receptors in the treatment of diseases
|
|
MXPA04003536A
(es)
|
2001-10-15 |
2004-07-23 |
Genentech Inc |
Tratamiento y diagnostico de estados resistentes a insulina.
|
|
US7103929B2
(en)
*
|
2002-03-12 |
2006-09-12 |
Little Rapids Corporation |
Disposable bedding with absorbent region
|
|
WO2004042009A2
(en)
*
|
2002-10-30 |
2004-05-21 |
Genentech, Inc. |
Inhibition of il-17 production
|
|
US7282204B2
(en)
*
|
2003-03-10 |
2007-10-16 |
Schering Corporation |
Uses of IL-23 agonists and antagonists; related reagents
|
|
EP1644415B1
(en)
|
2003-06-23 |
2010-12-01 |
Genetics Institute, LLC |
Antibodies against interleukin-22 and uses therefor
|
|
EP2784084B2
(en)
|
2003-07-08 |
2023-10-04 |
Novartis Pharma AG |
Antagonist antibodies to IL-17A/F heterologous polypeptides
|
|
AU2004289303A1
(en)
*
|
2003-11-10 |
2005-05-26 |
Synta Pharmaceuticals, Corp. |
Fused heterocyclic compounds
|
|
AU2004289304A1
(en)
*
|
2003-11-10 |
2005-05-26 |
Synta Pharmaceuticals, Corp. |
Pyridine compounds
|
|
EP1689403A4
(en)
|
2003-11-10 |
2007-09-05 |
Synta Pharmaceuticals Corp |
HETEROARYL-hydrazone compounds
|
|
HUE026260T2
(en)
|
2003-11-21 |
2016-06-28 |
Ucb Biopharma Sprl |
A method for treating multiple sclerosis by inhibiting IL-17 activity
|
|
CN1942201B
(zh)
*
|
2004-02-17 |
2012-06-20 |
先灵公司 |
调节il-23活性的方法;相关试剂
|
|
US20050287593A1
(en)
*
|
2004-05-03 |
2005-12-29 |
Schering Corporation |
Use of cytokine expression to predict skin inflammation; methods of treatment
|
|
BRPI0510617A
(pt)
|
2004-05-03 |
2007-10-30 |
Schering Corp |
uso de expressão de il-17 para prever inflamação de pele; processos de tratamento
|
|
US7910540B2
(en)
*
|
2004-06-10 |
2011-03-22 |
Zymogenetics, Inc. |
Soluble ZcytoR14, anti-ZcytoR14 antibodies and binding partners and methods of using in inflammation
|
|
US7629691B2
(en)
|
2004-06-16 |
2009-12-08 |
Honeywell International Inc. |
Conductor geometry for electronic circuits fabricated on flexible substrates
|
|
GB0417487D0
(en)
|
2004-08-05 |
2004-09-08 |
Novartis Ag |
Organic compound
|
|
AR051444A1
(es)
*
|
2004-09-24 |
2007-01-17 |
Centocor Inc |
Proteinas derivadas de inmunoglobulina especifica de il-23p40, composiciones, epitopos, metodos y usos
|
|
GB0425569D0
(en)
|
2004-11-19 |
2004-12-22 |
Celltech R&D Ltd |
Biological products
|
|
AU2005313971B2
(en)
|
2004-12-08 |
2011-10-13 |
Immunomedics, Inc. |
Methods and compositions for immunotherapy and detection of inflammatory and immune-dysregulatory disease, infectious disease, pathologic angiogenesis and cancer
|
|
GT200600065A
(es)
*
|
2005-02-14 |
2006-10-02 |
|
Anticuerpos para interleucina-17f y otros antagonistas de la señalizacion de il-17f y sus usos
|
|
WO2006132788A2
(en)
|
2005-06-06 |
2006-12-14 |
Genentech, Inc. |
Transgenic models for different genes and their use for gene characterization
|
|
US20080199460A1
(en)
|
2005-09-01 |
2008-08-21 |
Schering Corporation |
Use of IL-23 and IL-17 antagonists to treat autoimmune ocular inflammatory disease
|
|
US20070249533A1
(en)
|
2005-09-28 |
2007-10-25 |
Levin Steven D |
Il-17a and il-17f antagonists and methods of using the same
|
|
UA96139C2
(uk)
|
2005-11-08 |
2011-10-10 |
Дженентек, Інк. |
Антитіло до нейропіліну-1 (nrp1)
|
|
EP1963368B3
(en)
|
2005-12-13 |
2020-06-10 |
Eli Lilly And Company |
Anti-il-17 antibodies
|
|
WO2007081988A2
(en)
*
|
2006-01-11 |
2007-07-19 |
Aurora Specialty Chemistries Corp. |
Stable dispersion of dbnpa in viscosified brine
|
|
BRPI0706788A2
(pt)
|
2006-01-31 |
2011-04-05 |
Novartis Ag |
anticorpos antagonistas il-17
|
|
EP1996622A2
(en)
|
2006-03-10 |
2008-12-03 |
Zymogenetics, Inc. |
Antibodies that bind both il-17a and il-17f and methods of using the same
|
|
US7790163B2
(en)
|
2006-03-10 |
2010-09-07 |
Zymogenetics, Inc. |
Antibodies that bind both IL-17A and IL-17F and methods of using the same
|
|
US7790862B2
(en)
|
2006-06-13 |
2010-09-07 |
Zymogenetics, Inc. |
IL-17 and IL-23 antagonists and methods of using the same
|
|
US7910703B2
(en)
|
2006-03-10 |
2011-03-22 |
Zymogenetics, Inc. |
Antagonists to IL-17A, IL-17F, and IL-23P19 and methods of use
|
|
TW200815469A
(en)
|
2006-06-23 |
2008-04-01 |
Astrazeneca Ab |
Compounds
|
|
GB0612928D0
(en)
|
2006-06-29 |
2006-08-09 |
Ucb Sa |
Biological products
|
|
GB0620729D0
(en)
|
2006-10-18 |
2006-11-29 |
Ucb Sa |
Biological products
|
|
US7790676B2
(en)
|
2007-03-28 |
2010-09-07 |
Zymogenetics, Inc. |
Soluble IL-17RA/RC fusion proteins
|
|
JP5116842B2
(ja)
*
|
2007-04-27 |
2013-01-09 |
ザイモジェネティクス, インコーポレイテッド |
IL−17AおよびIl−17Fの両方に結合する抗体ならびにそれを使用する方法
|
|
EP2150564A2
(en)
|
2007-04-27 |
2010-02-10 |
ZymoGenetics, Inc. |
Antagonists to il-17a, il-17f, and il-23p19 and methods of use
|
|
US20100239590A1
(en)
|
2007-06-20 |
2010-09-23 |
Schering Corporation |
Joint destruction biomarkers for anti-il-17a therapy of inflammatory joint disease
|
|
ES2614735T3
(es)
|
2007-07-23 |
2017-06-01 |
Janssen Biotech, Inc. |
Métodos y composiciones para tratar los trastornos relacionados con fibrosis usando antagonistas de la IL-17
|
|
US20110300154A1
(en)
|
2007-08-21 |
2011-12-08 |
Children's Medical Center Corporation |
Treatment of airway hyperreactivity
|
|
GB0807413D0
(en)
|
2008-04-23 |
2008-05-28 |
Ucb Pharma Sa |
Biological products
|
|
RU2474588C2
(ru)
|
2008-05-05 |
2013-02-10 |
Новиммун Са |
Перекрестно-реактивные антитела анти-il-17a/il-17f и способы их применения
|
|
US8790642B2
(en)
|
2008-08-29 |
2014-07-29 |
Genentech, Inc. |
Cross-reactive and bispecific anti-IL-17A/F antibodies
|
|
MA33248B1
(fr)
|
2009-04-01 |
2012-05-02 |
Genentech Inc |
Traitement de troubles résistant à l'insuline
|
|
CN102458437B
(zh)
|
2009-05-05 |
2015-06-10 |
诺维莫尼公司 |
抗il-17f抗体及其使用方法
|