JP2013543842A5 - - Google Patents

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Publication number
JP2013543842A5
JP2013543842A5 JP2013534442A JP2013534442A JP2013543842A5 JP 2013543842 A5 JP2013543842 A5 JP 2013543842A5 JP 2013534442 A JP2013534442 A JP 2013534442A JP 2013534442 A JP2013534442 A JP 2013534442A JP 2013543842 A5 JP2013543842 A5 JP 2013543842A5
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JP
Japan
Prior art keywords
alkyl
pharmaceutically acceptable
acceptable salt
halo
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2013534442A
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English (en)
Japanese (ja)
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JP5802756B2 (ja
JP2013543842A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/IB2011/054675 external-priority patent/WO2012052948A1/en
Publication of JP2013543842A publication Critical patent/JP2013543842A/ja
Publication of JP2013543842A5 publication Critical patent/JP2013543842A5/ja
Application granted granted Critical
Publication of JP5802756B2 publication Critical patent/JP5802756B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2013534442A 2010-10-20 2011-10-19 スムーズンド受容体モジュレーターとしてのピリジン−２−誘導体 Expired - Fee Related JP5802756B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40510110P 2010-10-20 2010-10-20
US61/405,101 2010-10-20
PCT/IB2011/054675 WO2012052948A1 (en) 2010-10-20 2011-10-19 Pyridine- 2- derivatives as smoothened receptor modulators

Publications (3)

Publication Number Publication Date
JP2013543842A JP2013543842A (ja) 2013-12-09
JP2013543842A5 true JP2013543842A5 (enExample) 2014-11-06
JP5802756B2 JP5802756B2 (ja) 2015-11-04

Family

ID=44936320

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013534442A Expired - Fee Related JP5802756B2 (ja) 2010-10-20 2011-10-19 スムーズンド受容体モジュレーターとしてのピリジン−２−誘導体

Country Status (6)

Country Link
US (1) US9056865B2 (enExample)
EP (1) EP2630134B9 (enExample)
JP (1) JP5802756B2 (enExample)
CA (1) CA2813162C (enExample)
ES (1) ES2543151T3 (enExample)
WO (1) WO2012052948A1 (enExample)

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WO2016203404A1 (en) 2015-06-19 2016-12-22 Novartis Ag Compounds and compositions for inhibiting the activity of shp2
EP3310774B1 (en) 2015-06-19 2020-04-29 Novartis AG Compounds and compositions for inhibiting the activity of shp2
US10779980B2 (en) 2016-04-27 2020-09-22 Synerz Medical, Inc. Intragastric device for treating obesity
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ES2941903T3 (es) * 2016-07-05 2023-05-26 Bayer Cropscience Ag Procedimiento para la preparación de derivados de piridina halogenada
ES2964956T3 (es) 2017-01-10 2024-04-10 Novartis Ag Combinación farmacéutica que comprende un inhibidor de ALK y un inhibidor de SHP2
EP3911649A1 (en) * 2019-01-17 2021-11-24 F. Hoffmann-La Roche AG A process for the preparation of tetrahydropyridopyrimidines
CN117500795A (zh) * 2021-03-18 2024-02-02 维泰瑞隆有限公司 受体相互作用蛋白1抑制剂、其制备及用途

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