JP2013539370A5 - - Google Patents
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- JP2013539370A5 JP2013539370A5 JP2013528269A JP2013528269A JP2013539370A5 JP 2013539370 A5 JP2013539370 A5 JP 2013539370A5 JP 2013528269 A JP2013528269 A JP 2013528269A JP 2013528269 A JP2013528269 A JP 2013528269A JP 2013539370 A5 JP2013539370 A5 JP 2013539370A5
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- Prior art keywords
- host cell
- recombinant host
- conversion
- product
- polypeptide
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38056310P | 2010-09-07 | 2010-09-07 | |
| US61/380,563 | 2010-09-07 | ||
| US201161466557P | 2011-03-23 | 2011-03-23 | |
| US61/466,557 | 2011-03-23 | ||
| PCT/US2011/050689 WO2012033832A2 (en) | 2010-09-07 | 2011-09-07 | Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016138178A Division JP6266707B2 (ja) | 2010-09-07 | 2016-07-13 | ピルベートからアセトラクテートへの変換を触媒するポリペプチドをコードするポリヌクレオチドの組込み |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013539370A JP2013539370A (ja) | 2013-10-24 |
| JP2013539370A5 true JP2013539370A5 (enExample) | 2014-10-16 |
| JP6008858B2 JP6008858B2 (ja) | 2016-10-19 |
Family
ID=45811143
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013528269A Active JP6008858B2 (ja) | 2010-09-07 | 2011-09-07 | ピルベートからアセトラクテートへの変換を触媒するポリペプチドをコードするポリヌクレオチドの組込み |
| JP2016138178A Expired - Fee Related JP6266707B2 (ja) | 2010-09-07 | 2016-07-13 | ピルベートからアセトラクテートへの変換を触媒するポリペプチドをコードするポリヌクレオチドの組込み |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016138178A Expired - Fee Related JP6266707B2 (ja) | 2010-09-07 | 2016-07-13 | ピルベートからアセトラクテートへの変換を触媒するポリペプチドをコードするポリヌクレオチドの組込み |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US9267157B2 (enExample) |
| EP (2) | EP2614138B1 (enExample) |
| JP (2) | JP6008858B2 (enExample) |
| KR (1) | KR20130105649A (enExample) |
| CN (2) | CN105950525A (enExample) |
| AU (2) | AU2011299303B2 (enExample) |
| BR (1) | BR112013005386A2 (enExample) |
| CA (2) | CA2810244C (enExample) |
| MX (2) | MX356668B (enExample) |
| NZ (2) | NZ707800A (enExample) |
| WO (1) | WO2012033832A2 (enExample) |
| ZA (1) | ZA201301237B (enExample) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9303225B2 (en) | 2005-10-26 | 2016-04-05 | Butamax Advanced Biofuels Llc | Method for the production of isobutanol by recombinant yeast |
| US8945899B2 (en) | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
| WO2008130995A2 (en) | 2007-04-18 | 2008-10-30 | E. I. Du Pont De Nemours And Company | Fermentive production of isobutanol using highly active ketol-acid reductoisomerase enzymes |
| US8188250B2 (en) | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
| AU2009296224B2 (en) | 2008-09-29 | 2015-02-12 | Butamax(Tm) Advanced Biofuels Llc | Increased heterologous Fe-S enzyme actiivty in yeast |
| BR112012006939A2 (pt) * | 2009-09-29 | 2015-09-08 | Butamax Tm Advanced Biofuels | célula hospedeira de produção de levedura recombinante e método para a produção de um produto selecionado do grupo que consiste em 2,3-butanodiol, isobutanol, 2-butanol, 1-butanol, 2-butanona, valina, leucina, ácido lático, ácido málico, álcool, isoampilico e isoprenoides |
| EP2519628A2 (en) | 2009-12-29 | 2012-11-07 | Butamax (TM) Advanced Biofuels LLC | Alcohol dehydrogenases (adh) useful for fermentive production of lower alkyl alcohols |
| AU2010339511A1 (en) | 2009-12-29 | 2012-07-05 | Butamax(Tm) Advanced Biofuels Llc | Expression of hexose kinase in recombinant host cells |
| KR20130027063A (ko) | 2010-02-17 | 2013-03-14 | 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 | Fe-s 클러스터 요구성 단백질의 활성 향상 |
| JP2013528399A (ja) | 2010-06-18 | 2013-07-11 | ブタマックス(ティーエム) アドバンスド バイオフューエルズ エルエルシー | 抽出発酵におけるアルコール除去のための、油に由来する抽出溶媒 |
| CA2810244C (en) | 2010-09-07 | 2020-10-06 | Butamax(Tm) Advanced Biofuels Llc | Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion |
| BRPI1004630B1 (pt) * | 2010-11-12 | 2019-01-02 | Jose Antonio Fabre | fonte energética líquida com iniciação por compressão |
| US8759044B2 (en) | 2011-03-23 | 2014-06-24 | Butamax Advanced Biofuels Llc | In situ expression of lipase for enzymatic production of alcohol esters during fermentation |
| US8765425B2 (en) | 2011-03-23 | 2014-07-01 | Butamax Advanced Biofuels Llc | In situ expression of lipase for enzymatic production of alcohol esters during fermentation |
| US9790521B2 (en) | 2011-03-24 | 2017-10-17 | Butamax Advanced Biofuels Llc | Host cells and methods for production of isobutanol |
| BR112013032319A2 (pt) | 2011-06-17 | 2016-12-20 | Butamax Advanced Biofuels Llc | métodos da geração de coprodutos de destilação, coprodutos de destilação, método para atenuar o impacto de contaminantes de fermentação, método para a redução da contaminação por micotoxinas, método para a redução da variabilidade do teor de lipídeos, método para aumento do teor de triglicerídeos, método de produção de um coproduto de destilação para o combustível e método de produção de um coproduto destilação para o biodiesel |
| CN105473726B (zh) | 2011-07-28 | 2021-03-12 | 布特马斯先进生物燃料有限责任公司 | 酮异戊酸脱羧酶及其使用方法 |
| JP2015503350A (ja) | 2011-12-30 | 2015-02-02 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | アルコールの発酵生産 |
| WO2013102147A2 (en) | 2011-12-30 | 2013-07-04 | Butamax (Tm) Advanced Biofuels Llc | Genetic switches for butanol production |
| AU2013235391A1 (en) | 2012-03-23 | 2014-09-04 | Butamax Advanced Biofuels Llc | Acetate supplemention of medium for butanologens |
| CA2873109A1 (en) | 2012-05-11 | 2013-11-28 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase enzymes and methods of use |
| CA2881407A1 (en) | 2012-08-22 | 2014-02-27 | Butamax Advanced Biofuels Llc | Production of fermentation products |
| WO2014043288A1 (en) * | 2012-09-12 | 2014-03-20 | Butamax Advanced Biofuels Llc | Processes and systems for the production of fermentation products |
| US9840724B2 (en) | 2012-09-21 | 2017-12-12 | Butamax Advanced Biofuels Llc | Production of renewable hydrocarbon compositions |
| BR112015006691A2 (pt) * | 2012-09-26 | 2017-12-12 | Butamax Advanced Biofuels Llc | métodos, célula hospedeira recombinante, composição, polipeptídeo, polinucleotídeos e vetor recombinante |
| US9273330B2 (en) | 2012-10-03 | 2016-03-01 | Butamax Advanced Biofuels Llc | Butanol tolerance in microorganisms |
| WO2014106107A2 (en) | 2012-12-28 | 2014-07-03 | Butamax (Tm) Advanced Biofuels Llc | Dhad variants for butanol production |
| WO2014159309A1 (en) | 2013-03-12 | 2014-10-02 | Butamax Advanced Biofuels Llc | Processes and systems for the production of alcohols |
| CN105378057A (zh) | 2013-03-14 | 2016-03-02 | 纳幕尔杜邦公司 | 用于丁醇生产的甘油3-磷酸脱氢酶 |
| US9771602B2 (en) | 2013-03-15 | 2017-09-26 | Butamax Advanced Biofuels Llc | Competitive growth and/or production advantage for butanologen microorganism |
| WO2014151190A1 (en) | 2013-03-15 | 2014-09-25 | Butamax Advanced Biofuels Llc | Dhad variants and methods of screening |
| WO2014151645A1 (en) | 2013-03-15 | 2014-09-25 | Butamax Advanced Biofuels Llc | Process for maximizing biomass growth and butanol yield by feedback control |
| US9663759B2 (en) | 2013-07-03 | 2017-05-30 | Butamax Advanced Biofuels Llc | Partial adaptation for butanol production |
| CN103627698A (zh) * | 2013-12-05 | 2014-03-12 | 江南大学 | 乙偶姻高耐受性菌株的选育和用该菌株发酵生产乙偶姻 |
| US10280438B2 (en) | 2014-08-11 | 2019-05-07 | Butamax Advanced Biofuels Llc | Method for the production of yeast |
| WO2016094334A1 (en) * | 2014-12-08 | 2016-06-16 | Lanzatech New Zealand Limited | Recombinant microorganisms exhibiting increased flux through a fermentation pathway |
| CN109897871A (zh) * | 2017-12-07 | 2019-06-18 | 中国科学院大连化学物理研究所 | 一种酶法催化二元醇制备二元胺的方法 |
| CN110468092B (zh) * | 2019-08-26 | 2021-10-01 | 天津科技大学 | 一株高产l-缬氨酸的基因工程菌及其构建方法与应用 |
| CN115927136B (zh) * | 2022-08-01 | 2023-06-09 | 长江师范学院 | 一种产四甲基吡嗪的重组乳酸菌、其构建方法及其应用 |
| CN116024201B (zh) * | 2022-12-23 | 2024-03-19 | 天津大学 | α-乙酰乳酸脱羧酶突变体及其在生产乙偶姻中的应用 |
| CN116640753B (zh) * | 2023-07-20 | 2023-10-13 | 中国科学院天津工业生物技术研究所 | 丙酮酸脱羧酶基因FvPDC6及其在提高威尼斯镰刀菌菌丝蛋白产量中的应用 |
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|---|---|---|---|---|
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US20070031950A1 (en) | 1998-09-11 | 2007-02-08 | Winkler Aaron A | Production of D-lactic acid with yeast |
| US6432688B1 (en) | 1999-01-18 | 2002-08-13 | Daicel Chemical Industries, Ltd. | Amino alcohol dehydrogenase converts keto alcohol to amino alcohol and amino alcohol to keto alcohol |
| US7405068B2 (en) | 2003-05-02 | 2008-07-29 | Tate & Lyle Ingredients Americas, Inc. | Pyruvate producing yeast strain |
| GB0329722D0 (en) | 2003-12-23 | 2004-01-28 | Delta Biotechnology Ltd | Modified plasmid and use thereof |
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| US9303225B2 (en) | 2005-10-26 | 2016-04-05 | Butamax Advanced Biofuels Llc | Method for the production of isobutanol by recombinant yeast |
| US8945899B2 (en) | 2007-12-20 | 2015-02-03 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase using NADH |
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| US8828704B2 (en) | 2006-05-02 | 2014-09-09 | Butamax Advanced Biofuels Llc | Fermentive production of four carbon alcohols |
| US8962298B2 (en) | 2006-05-02 | 2015-02-24 | Butamax Advanced Biofuels Llc | Recombinant host cell comprising a diol dehydratase |
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| US8518678B2 (en) | 2007-12-21 | 2013-08-27 | Butamax(Tm) Advanced Biofuels Llc | Strain comprising increased expression of a CFA coding region for butanol production |
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| US8455239B2 (en) | 2007-12-23 | 2013-06-04 | Gevo, Inc. | Yeast organism producing isobutanol at a high yield |
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| US8188250B2 (en) | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
| US8389252B2 (en) | 2008-05-12 | 2013-03-05 | Butamax(Tm) Advanced Biofuels Llc | Yeast strain for production of four carbon alcohols |
| US8906666B2 (en) | 2008-05-22 | 2014-12-09 | Butamax Advanced Biofuels Llc | Engineering resistance to aliphatic alcohols |
| US8828695B2 (en) | 2008-06-04 | 2014-09-09 | Butamax Advanced Biofuels Llc | Method for producing butanol using two-phase extractive fermentation |
| AU2009256209A1 (en) * | 2008-06-04 | 2009-12-10 | Butamax(Tm) Advanced Biofuels Llc | Deletion mutants for the production of isobutanol |
| MX2010013182A (es) | 2008-06-04 | 2011-01-14 | Butamax Tm Advanced Biofuels | Metodo para producir butanol mediante el uso de fermentacion extractiva de dos fases. |
| BRPI0913681A2 (pt) | 2008-09-29 | 2019-09-24 | Butamax Advanced Biofuels Llc | "célula bacteriana ácido-lática recombinante e método de produção de isobutanol" |
| AU2009296224B2 (en) | 2008-09-29 | 2015-02-12 | Butamax(Tm) Advanced Biofuels Llc | Increased heterologous Fe-S enzyme actiivty in yeast |
| AU2009296227A1 (en) | 2008-09-29 | 2010-04-01 | Butamax(Tm) Advanced Biofuels Llc | Enhanced pyruvate to 2,3-butanediol conversion in lactic acid bacteria |
| US20100081154A1 (en) | 2008-09-29 | 2010-04-01 | Butamax(Tm) Advanced Biofuels Llc | IDENTIFICATION AND USE OF BACTERIAL [2Fe-2S] DIHYDROXY-ACID DEHYDRATASES |
| US20160222370A1 (en) | 2008-09-29 | 2016-08-04 | Butamax Advanced Biofuels Llc | Recombinant Yeast Host Cell With Fe-S Cluster Proteins And Methods Of Using Thereof |
| AU2009296232A1 (en) | 2008-09-29 | 2010-04-01 | Butamax(Tm) Advanced Biofuels Llc | Enhanced iron-sulfur cluster formation for increased dihydroxy-acid dehydratase activity in lactic acid bacteria |
| AU2009320163B2 (en) | 2008-10-27 | 2014-10-02 | Butamax(Tm) Advanced Biofuels Llc | Carbon pathway optimized production hosts for the production of isobutanol |
| US8828694B2 (en) | 2008-11-13 | 2014-09-09 | Butamax Advanced Biofuels Llc | Production of isobutanol in yeast mitochondria |
| US8465964B2 (en) | 2008-11-13 | 2013-06-18 | Butamax (TM) Advanced Biofules LLC | Increased production of isobutanol in yeast with reduced mitochondrial amino acid biosynthesis |
| US8652823B2 (en) | 2008-12-03 | 2014-02-18 | Butamax(Tm) Advanced Biofuels Llc | Strain for butanol production with increased membrane unsaturated trans fatty acids |
| DE102008062847A1 (de) | 2008-12-23 | 2010-06-24 | Jt Optical Engine Gmbh + Co. Kg | Spleißverbindung zwischen zwei optischen Fasern sowie Verfahren zum Herstellen einer solchen Spleißverbindung |
| WO2010075504A2 (en) | 2008-12-23 | 2010-07-01 | Gevo, Inc. | Engineered microorganisms for the production of one or more target compounds |
| US8455225B2 (en) | 2008-12-29 | 2013-06-04 | Butamax Advanced Biofuels Llc | Yeast with increased butanol tolerance involving high osmolarity/glycerol response pathway |
| US8557562B2 (en) | 2008-12-29 | 2013-10-15 | Butamax(Tm) Advanced Biofuels Llc | Yeast with increased butanol tolerance involving filamentous growth response |
| US8795992B2 (en) | 2008-12-29 | 2014-08-05 | Butamax Advanced Biofuels Llc | Yeast with increased butanol tolerance involving cell wall integrity pathway |
| US8614085B2 (en) | 2009-02-27 | 2013-12-24 | Butamax(Tm) Advanced Biofuels Llc | Yeast with increased butanol tolerance involving a multidrug efflux pump gene |
| EP2419517A2 (en) | 2009-04-13 | 2012-02-22 | Butamax(TM) Advanced Biofuels LLC | Method for producing butanol using extractive fermentation |
| US20120058541A1 (en) | 2009-05-22 | 2012-03-08 | Butamax(Tm) Advanced Biofuels Llc | Engineering resistance to aliphatic alcohols |
| AU2010300722A1 (en) | 2009-09-29 | 2012-04-12 | Butamax(Tm) Advanced Biofuels Llc | Improved flux to acetolactate-derived products in lactic acid bacteria |
| BR112012006939A2 (pt) | 2009-09-29 | 2015-09-08 | Butamax Tm Advanced Biofuels | célula hospedeira de produção de levedura recombinante e método para a produção de um produto selecionado do grupo que consiste em 2,3-butanodiol, isobutanol, 2-butanol, 1-butanol, 2-butanona, valina, leucina, ácido lático, ácido málico, álcool, isoampilico e isoprenoides |
| JP5805094B2 (ja) | 2009-09-29 | 2015-11-04 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | 高有効性のケトール酸レダクトイソメラーゼ酵素を用いたイソブタノールの発酵生産 |
| US20110195505A1 (en) | 2009-10-08 | 2011-08-11 | Butamax(Tm) Advanced Biofuels Llc | Bacterial strains for butanol production |
| AU2010339511A1 (en) | 2009-12-29 | 2012-07-05 | Butamax(Tm) Advanced Biofuels Llc | Expression of hexose kinase in recombinant host cells |
| EP2519628A2 (en) | 2009-12-29 | 2012-11-07 | Butamax (TM) Advanced Biofuels LLC | Alcohol dehydrogenases (adh) useful for fermentive production of lower alkyl alcohols |
| KR20130027063A (ko) | 2010-02-17 | 2013-03-14 | 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 | Fe-s 클러스터 요구성 단백질의 활성 향상 |
| MX2012014550A (es) | 2010-06-17 | 2013-01-29 | Butamax Tm Advanced Biofuels | Cultivo de produccion de levadura para la produccion de butanol. |
| US8871488B2 (en) | 2010-06-18 | 2014-10-28 | Butamax Advanced Biofuels Llc | Recombinant host cells comprising phosphoketolases |
| JP2013528399A (ja) | 2010-06-18 | 2013-07-11 | ブタマックス(ティーエム) アドバンスド バイオフューエルズ エルエルシー | 抽出発酵におけるアルコール除去のための、油に由来する抽出溶媒 |
| US8697404B2 (en) | 2010-06-18 | 2014-04-15 | Butamax Advanced Biofuels Llc | Enzymatic production of alcohol esters for recovery of diols produced by fermentation |
| CA2810244C (en) | 2010-09-07 | 2020-10-06 | Butamax(Tm) Advanced Biofuels Llc | Integration of a polynucleotide encoding a polypeptide that catalyzes pyruvate to acetolactate conversion |
| US9790521B2 (en) | 2011-03-24 | 2017-10-17 | Butamax Advanced Biofuels Llc | Host cells and methods for production of isobutanol |
| US20120258873A1 (en) | 2011-04-06 | 2012-10-11 | Butamax(Tm) Advanced Biofuels Llc | Reduction of 2,3-dihydroxy-2-methyl butyrate (dhmb) in butanol production |
| CN103814135A (zh) | 2011-06-17 | 2014-05-21 | 布特马斯先进生物燃料有限责任公司 | 木质纤维素水解产物作为原料用于异丁醇发酵 |
| CN105473726B (zh) | 2011-07-28 | 2021-03-12 | 布特马斯先进生物燃料有限责任公司 | 酮异戊酸脱羧酶及其使用方法 |
| JP2015503350A (ja) | 2011-12-30 | 2015-02-02 | ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー | アルコールの発酵生産 |
| WO2013102147A2 (en) | 2011-12-30 | 2013-07-04 | Butamax (Tm) Advanced Biofuels Llc | Genetic switches for butanol production |
| AU2013235391A1 (en) | 2012-03-23 | 2014-09-04 | Butamax Advanced Biofuels Llc | Acetate supplemention of medium for butanologens |
| CA2873109A1 (en) | 2012-05-11 | 2013-11-28 | Butamax Advanced Biofuels Llc | Ketol-acid reductoisomerase enzymes and methods of use |
| CA2881407A1 (en) | 2012-08-22 | 2014-02-27 | Butamax Advanced Biofuels Llc | Production of fermentation products |
| US9840724B2 (en) | 2012-09-21 | 2017-12-12 | Butamax Advanced Biofuels Llc | Production of renewable hydrocarbon compositions |
| BR112015006691A2 (pt) | 2012-09-26 | 2017-12-12 | Butamax Advanced Biofuels Llc | métodos, célula hospedeira recombinante, composição, polipeptídeo, polinucleotídeos e vetor recombinante |
| US9273330B2 (en) | 2012-10-03 | 2016-03-01 | Butamax Advanced Biofuels Llc | Butanol tolerance in microorganisms |
| WO2014106107A2 (en) | 2012-12-28 | 2014-07-03 | Butamax (Tm) Advanced Biofuels Llc | Dhad variants for butanol production |
| US20140186911A1 (en) | 2012-12-28 | 2014-07-03 | Butamax Advanced Biofuels Llc | Recombinant host cells and methods for producing butanol |
| CN105378057A (zh) | 2013-03-14 | 2016-03-02 | 纳幕尔杜邦公司 | 用于丁醇生产的甘油3-磷酸脱氢酶 |
| US9771602B2 (en) | 2013-03-15 | 2017-09-26 | Butamax Advanced Biofuels Llc | Competitive growth and/or production advantage for butanologen microorganism |
| WO2014151190A1 (en) | 2013-03-15 | 2014-09-25 | Butamax Advanced Biofuels Llc | Dhad variants and methods of screening |
| WO2015009601A1 (en) | 2013-07-16 | 2015-01-22 | Butamax Advanced Biofuels Llc | Yeast with increased butanol tolerance involving cell wall proteins |
| WO2015103001A1 (en) | 2013-12-31 | 2015-07-09 | Butamax Advanced Biofuels Llc | Expression of a hap transcriptional complex subunit |
| US20160326551A1 (en) | 2013-12-31 | 2016-11-10 | Butamax Advanced Biofuels Llc | Isobutanol tolerance in yeast with an altered lipid profile |
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2011
- 2011-09-07 CA CA2810244A patent/CA2810244C/en not_active Expired - Fee Related
- 2011-09-07 AU AU2011299303A patent/AU2011299303B2/en not_active Ceased
- 2011-09-07 MX MX2017003595A patent/MX356668B/es unknown
- 2011-09-07 CN CN201610286698.7A patent/CN105950525A/zh active Pending
- 2011-09-07 KR KR1020137008786A patent/KR20130105649A/ko not_active Withdrawn
- 2011-09-07 BR BR112013005386A patent/BR112013005386A2/pt not_active IP Right Cessation
- 2011-09-07 CN CN2011800423458A patent/CN103080298A/zh active Pending
- 2011-09-07 CA CA3014993A patent/CA3014993A1/en not_active Abandoned
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- 2011-09-07 JP JP2013528269A patent/JP6008858B2/ja active Active
- 2011-09-07 MX MX2013002559A patent/MX346408B/es active IP Right Grant
- 2011-09-07 US US13/227,016 patent/US9267157B2/en active Active
- 2011-09-07 EP EP11824066.2A patent/EP2614138B1/en not_active Not-in-force
- 2011-09-07 WO PCT/US2011/050689 patent/WO2012033832A2/en not_active Ceased
- 2011-09-07 EP EP17188003.2A patent/EP3269806B1/en not_active Not-in-force
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2013
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2018
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