|
US4545931A
(en)
|
1983-01-03 |
1985-10-08 |
Scripps Clinic And Research Foundation |
Synthetic heat-stable enterotoxin polypeptide of Escherichia coli
|
|
CH658973A5
(fr)
|
1983-12-29 |
1986-12-31 |
Nestle Sa |
Produit aromatisant.
|
|
JPS6197229A
(ja)
|
1984-10-18 |
1986-05-15 |
Chugai Pharmaceut Co Ltd |
安定なエリトロポエチン製剤
|
|
DE3729863A1
(de)
|
1987-09-05 |
1989-03-16 |
Boehringer Mannheim Gmbh |
Stabilisierte erythropoietin-lyophilisate
|
|
JPS649938A
(en)
|
1987-06-30 |
1989-01-13 |
Agency Ind Science Techn |
Oral ingestive composition
|
|
JPH0223849A
(ja)
*
|
1988-06-08 |
1990-01-26 |
Morishita Pharmaceut Co Ltd |
ペプチド含有栄養輸液組成物
|
|
JPH03505334A
(ja)
|
1989-04-11 |
1991-11-21 |
イミユノバイオロジー・リサーチ・インスチチユート・インコーポレーテツド |
凍結乾燥されたペプチド製剤
|
|
US5130298A
(en)
|
1989-05-16 |
1992-07-14 |
Ethicon, Inc. |
Stabilized compositions containing epidermal growth factor
|
|
IT1240314B
(it)
|
1989-09-28 |
1993-12-07 |
Immunobiology Research Institutes, Inc. |
Formulazioni acquose stabilizzate di piccoli peptidi.
|
|
US5221495A
(en)
|
1990-04-13 |
1993-06-22 |
Colgate-Palmolive Company |
Enzyme stabilizing composition and stabilized enzyme containing built detergent compositions
|
|
US5451410A
(en)
|
1993-04-22 |
1995-09-19 |
Emisphere Technologies, Inc. |
Modified amino acids for encapsulating active agents
|
|
US6022858A
(en)
|
1991-12-20 |
2000-02-08 |
Novo Nordisk A/S |
Pharmaceutical formulation of human-growth hormone pretreated with zinc salt
|
|
US5969097A
(en)
|
1992-06-23 |
1999-10-19 |
G. D. Searle & Co. |
Human guanylin
|
|
US6284727B1
(en)
|
1993-04-07 |
2001-09-04 |
Scios, Inc. |
Prolonged delivery of peptides
|
|
US5681811A
(en)
|
1993-05-10 |
1997-10-28 |
Protein Delivery, Inc. |
Conjugation-stabilized therapeutic agent compositions, delivery and diagnostic formulations comprising same, and method of making and using the same
|
|
WO1996010996A1
(en)
|
1993-07-21 |
1996-04-18 |
The University Of Kentucky Research Foundation |
A multicompartment hard capsule with control release properties
|
|
US5518888A
(en)
|
1993-10-26 |
1996-05-21 |
Thomas Jefferson University |
ST receptor binding compounds and methods of using the same
|
|
US5489670A
(en)
|
1993-10-29 |
1996-02-06 |
G. D. Searle & Co. |
Human uroguanylin
|
|
DE69535787D1
(de)
|
1994-03-04 |
2008-08-28 |
Genentech Inc |
Verbesserte dnase flüssige lösungen
|
|
US5654278A
(en)
|
1994-10-13 |
1997-08-05 |
Novo Nordisk A/S |
Composition and method comprising growth hormone and leucine
|
|
US5593696A
(en)
|
1994-11-21 |
1997-01-14 |
Mcneil-Ppc, Inc. |
Stabilized composition of famotidine and sucralfate for treatment of gastrointestinal disorders
|
|
US5904935A
(en)
|
1995-06-07 |
1999-05-18 |
Alza Corporation |
Peptide/protein suspending formulations
|
|
ZA965368B
(en)
|
1995-07-14 |
1997-01-14 |
Novo Nordisk As |
A pharmaceutical formulation
|
|
US5980945A
(en)
|
1996-01-16 |
1999-11-09 |
Societe De Conseils De Recherches Et D'applications Scientifique S.A. |
Sustained release drug formulations
|
|
WO1997033568A1
(en)
|
1996-03-12 |
1997-09-18 |
Novartis Ag |
Filled gelatin capsules having a reduced degree of cross-linking
|
|
RU2203085C2
(ru)
|
1996-07-03 |
2003-04-27 |
Элзэ Копэрейшн |
Стабильный неводный препарат пептидного соединения, способ его получения и способ лечения гормон-зависимого заболевания у субъекта
|
|
US5916582A
(en)
|
1996-07-03 |
1999-06-29 |
Alza Corporation |
Aqueous formulations of peptides
|
|
US5932547A
(en)
|
1996-07-03 |
1999-08-03 |
Alza Corporation |
Non-aqueous polar aprotic peptide formulations
|
|
WO1998009645A1
(en)
|
1996-09-04 |
1998-03-12 |
Dott Research Laboratory |
Peptide-containing drug compositions for oral administration
|
|
US5705537A
(en)
|
1997-02-24 |
1998-01-06 |
Armstrong World Industries, Inc. |
Phenolic foams having a low formaldehyde evolution
|
|
US6541606B2
(en)
|
1997-12-31 |
2003-04-01 |
Altus Biologics Inc. |
Stabilized protein crystals formulations containing them and methods of making them
|
|
US6087478A
(en)
|
1998-01-23 |
2000-07-11 |
The Rockefeller University |
Crystal of the N-terminal domain of a STAT protein and methods of use thereof
|
|
AU5026599A
(en)
|
1998-07-23 |
2000-02-14 |
Novo Nordisk A/S |
A wet granulation method for preparing a stable pharmaceutical formulation
|
|
DE69921353T2
(de)
|
1998-11-27 |
2005-11-10 |
Kanji Takada |
Oral anzuwendendes arzneimittel zur wirkstoffverabreichung im magendarmtrakt
|
|
AU7700400A
(en)
|
1999-10-06 |
2001-05-10 |
Pharmacia Corporation |
Uroguanylin as an intestinal cancer inhibiting agent
|
|
AU2001220765A1
(en)
|
2000-01-24 |
2001-07-31 |
Medtronic Minimed, Inc. |
Mixed buffer system for stabilizing polypeptide formulations
|
|
JP2004501191A
(ja)
|
2000-06-28 |
2004-01-15 |
テバ ファーマシューティカル インダストリーズ リミティド |
カルベジロール
|
|
FR2811884B1
(fr)
|
2000-07-21 |
2003-01-31 |
Oreal |
Utilisation en cosmetique de betainates d'amidon et composition les comprenant associes a au moins un agent benefique pour les matieres keratiniques
|
|
US6613308B2
(en)
|
2000-09-19 |
2003-09-02 |
Advanced Inhalation Research, Inc. |
Pulmonary delivery in treating disorders of the central nervous system
|
|
WO2002026248A1
(en)
|
2000-09-29 |
2002-04-04 |
Cognetix, Inc. |
Stable peptide formulations
|
|
DE60127175T2
(de)
|
2000-12-21 |
2007-11-08 |
Nektar Therapeutics, San Carlos |
Lagerstabile pulverzusammensetzungen mit interleukin-4 rezeptor
|
|
CA2435835A1
(en)
|
2001-02-02 |
2002-08-15 |
Pharmacia Corporation |
Uroguanylin and cyclooxygenase-2 inhibitor combinations for inhibition of intestinal cancer
|
|
GB0104371D0
(en)
|
2001-02-22 |
2001-04-11 |
Clariant Int Ltd |
Color improving stabilizing compositions comprising leucine
|
|
US6573237B2
(en)
|
2001-03-16 |
2003-06-03 |
Eli Lilly And Company |
Protein formulations
|
|
CN103641892B
(zh)
|
2001-03-29 |
2015-06-17 |
药物协和公司 |
用于治疗组织炎症和癌变的鸟苷酸环化酶受体激动剂
|
|
AU2002355542A1
(en)
|
2001-08-09 |
2003-02-24 |
Doctor's Signature Sales And Marketing International Corp. ((Dba)) Life Force International |
Protonic formulation
|
|
US20030104996A1
(en)
|
2001-08-30 |
2003-06-05 |
Tiansheng Li |
L-methionine as a stabilizer for NESP/EPO in HSA-free formulations
|
|
US20040161776A1
(en)
|
2001-10-23 |
2004-08-19 |
Maddon Paul J. |
PSMA formulations and uses thereof
|
|
EP1458407A1
(en)
|
2001-12-21 |
2004-09-22 |
Novo Nordisk A/S |
Liquid composition of modified factor vii polypeptides
|
|
JP2003201256A
(ja)
|
2001-12-28 |
2003-07-18 |
Hisamitsu Pharmaceut Co Inc |
大腸送達性経口医薬製剤、大腸癌治療用経口医薬製剤および大腸炎治療用経口医薬製剤
|
|
DE10261126A1
(de)
|
2002-08-13 |
2004-03-04 |
Aventis Behring Gmbh |
Lagerungsstabile, flüssige Fibrinogen-Formulierung
|
|
AU2003301654A1
(en)
|
2002-10-22 |
2004-05-13 |
Dainippon Pharmaceutical Co., Ltd. |
Stabilized composition
|
|
EP1562626B1
(en)
|
2002-10-29 |
2007-11-28 |
ALZA Corporation |
Stabilized, solid-state polypeptide particles
|
|
KR20050088311A
(ko)
|
2002-12-11 |
2005-09-05 |
화이자 프로덕츠 인크. |
고지방 환경 내로의 활성 물질의 조절-방출
|
|
US7371727B2
(en)
|
2003-01-28 |
2008-05-13 |
Microbia, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
|
US7304036B2
(en)
|
2003-01-28 |
2007-12-04 |
Microbia, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
|
SG168407A1
(en)
|
2003-01-28 |
2011-02-28 |
Ironwood Pharmaceuticals Inc |
Methods and compositions for the treatment of gastrointestinal disorders
|
|
US7772188B2
(en)
|
2003-01-28 |
2010-08-10 |
Ironwood Pharmaceuticals, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
|
JP4353982B2
(ja)
|
2003-05-14 |
2009-10-28 |
インダス バイオテック ピーブイティ． エルティーディー． |
糖尿病処置用相乗作用組成物
|
|
BRPI0411114B8
(pt)
|
2003-06-10 |
2021-05-25 |
Lg Chemical Ltd |
solução aquosa estável de eritropoetina humana, não contendo albumina de soro
|
|
US7494979B2
(en)
|
2003-06-13 |
2009-02-24 |
Ironwood Pharmaceuticals, Inc. |
Method for treating congestive heart failure and other disorders
|
|
PL1644021T3
(pl)
|
2003-06-13 |
2013-01-31 |
Ironwood Pharmaceuticals Inc |
Sposoby i kompozycje do leczenia zaburzeń żołądkowo-jelitowych
|
|
KR100560697B1
(ko)
|
2003-08-06 |
2006-03-16 |
씨제이 주식회사 |
알부민을 함유하지 않는 에리스로포이에틴 제제
|
|
DE202004020676U1
(de)
|
2004-03-10 |
2005-11-10 |
Bioceuticals Arzneimittel Ag |
Erythropoietin-Flüssigformulierung
|
|
JP4744533B2
(ja)
|
2004-12-30 |
2011-08-10 |
ドゥビエル カンパニー リミテッド |
噴霧乾燥高分子型コレクチン属タンパク質及びその製造方法
|
|
EP1858352B1
(en)
|
2005-02-18 |
2013-06-05 |
Delante Health AS |
A composition comprising a powder containing microencapsulated polyunsaturated long-chain esterified fatty acids distributed in an effervescent base
|
|
KR101367544B1
(ko)
*
|
2005-06-10 |
2014-02-26 |
추가이 세이야쿠 가부시키가이샤 |
메글루민을 함유하는 단백질 제제의 안정화제, 및 그의이용
|
|
EP1940441A4
(en)
|
2005-08-19 |
2010-01-27 |
Ironwood Pharmaceuticals Inc |
COMPOSITIONS AND METHODS FOR TREATING GASTROINTESTINAL DISORDERS
|
|
WO2007044375A2
(en)
|
2005-10-06 |
2007-04-19 |
Nastech Pharmaceutical Company Inc. |
Pth formulations and methods of use
|
|
CA2627566A1
(en)
*
|
2005-10-28 |
2007-05-10 |
Nestec S.A. |
Methods for the use of branched chain amino acids
|
|
JP2009527504A
(ja)
|
2006-02-23 |
2009-07-30 |
イオメディックス スリープ インターナショナル エスアールエル |
良質な睡眠の誘導および維持のための組成物および方法
|
|
CA2652677A1
(en)
|
2006-02-24 |
2007-09-07 |
Ironwood Pharmaceuticals, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
|
ITMI20060629A1
(it)
|
2006-03-31 |
2007-10-01 |
Daniele Giovannone |
Composizioni solide orali a base di s-adenosilmetionina e processo per il loro ottenimento
|
|
US7960339B2
(en)
|
2006-07-10 |
2011-06-14 |
Österreichische Akademie der Wissenschaften |
Antimicrobial peptides
|
|
EP2049081B1
(en)
|
2006-08-09 |
2012-11-14 |
Intarcia Therapeutics, Inc. |
Osmotic delivery systems and piston assemblies
|
|
AU2007289344B2
(en)
|
2006-08-31 |
2011-04-14 |
Novartis Ag |
Pharmaceutical compositions comprising hGH for oral delivery
|
|
US7705132B2
(en)
|
2006-10-20 |
2010-04-27 |
Amgen Inc. |
Stable polypeptide formulations
|
|
WO2008078189A2
(en)
|
2006-12-20 |
2008-07-03 |
Bayer Healthcare Llc |
Factor vii and viia compositions
|
|
WO2008096804A1
(ja)
*
|
2007-02-07 |
2008-08-14 |
Teika Pharmaceutical Co., Ltd. |
ラタノプロスト含有点眼剤
|
|
US8779090B2
(en)
|
2007-02-26 |
2014-07-15 |
Ironwood Pharmaceuticals, Inc. |
Methods and compositions for the treatment of heart failure and other disorders
|
|
JP4906546B2
(ja)
*
|
2007-03-15 |
2012-03-28 |
株式会社ヤクルト本社 |
レボホリナート含有水溶液製剤
|
|
EP2527360B1
(en)
|
2007-06-04 |
2015-10-28 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
|
JP2009256281A
(ja)
*
|
2008-04-21 |
2009-11-05 |
Teika Seiyaku Kk |
イソプロピルウノプロストン含有点眼剤組成物
|
|
CN117530912A
(zh)
*
|
2008-08-15 |
2024-02-09 |
硬木药品公司 |
适合口服给药的鸟苷酸环化酶-c受体激动剂多肽的稳定的固体制剂
|
|
US20120009225A1
(en)
|
2008-09-04 |
2012-01-12 |
Ironwood Pharmaceuticals, Inc. |
Stable Solid Formulation of Therapeutic Polypeptides Suitable for Oral Administration
|
|
US20120039949A1
(en)
|
2008-09-04 |
2012-02-16 |
Ironwood Pharmaceuticals, Inc. |
Stable Solid Formulations of GC-C Receptor Agonist Polypeptides Suitable for Oral Administration
|
|
CA2994066A1
(en)
|
2008-12-03 |
2010-06-10 |
Synergy Pharmaceuticals, Inc. |
Formulations of guanylate cyclase c agonists and methods of use
|
|
CA2770077A1
(en)
*
|
2009-08-06 |
2011-02-10 |
Ironwood Pharmaceuticals, Inc. |
Formulations comprising linaclotide
|
|
CA2770334A1
(en)
|
2009-08-12 |
2011-02-17 |
Forest Laboratories Holdings Limited |
Orally disintegrating compositions of linaclotide
|
|
DK2603232T3
(da)
|
2010-08-11 |
2019-12-09 |
Ironwood Pharmaceuticals Inc |
Stabile formuleringer af linaclotid
|
|
WO2012155101A1
(en)
|
2011-05-11 |
2012-11-15 |
Ironwood Pharmaceuticals, Inc. |
Treatments for gastrointestinal disorders
|
|
WO2012170766A1
(en)
|
2011-06-08 |
2012-12-13 |
Ironwood Pharmaceuticals, Inc. |
Treatments for gastrointestinal disorders
|
|
US9617305B2
(en)
|
2011-06-08 |
2017-04-11 |
Ironwood Pharmaceuticals, Inc. |
Treatments for gastrointestinal disorders
|
|
US9708371B2
(en)
|
2011-08-17 |
2017-07-18 |
Ironwood Pharmaceuticals, Inc. |
Treatments for gastrointestinal disorders
|