JP2013523082A5 - - Google Patents
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- JP2013523082A5 JP2013523082A5 JP2012543839A JP2012543839A JP2013523082A5 JP 2013523082 A5 JP2013523082 A5 JP 2013523082A5 JP 2012543839 A JP2012543839 A JP 2012543839A JP 2012543839 A JP2012543839 A JP 2012543839A JP 2013523082 A5 JP2013523082 A5 JP 2013523082A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- isolated
- apc
- group
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 23
- 239000002157 polynucleotide Substances 0.000 claims 8
- 102000040430 polynucleotide Human genes 0.000 claims 8
- 108091033319 polynucleotide Proteins 0.000 claims 8
- 102000004196 processed proteins & peptides Human genes 0.000 claims 8
- 150000001413 amino acids Chemical group 0.000 claims 7
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 claims 7
- 230000001939 inductive effect Effects 0.000 claims 5
- 238000000034 method Methods 0.000 claims 5
- 239000000427 antigen Substances 0.000 claims 4
- 108091007433 antigens Proteins 0.000 claims 4
- 102000036639 antigens Human genes 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 206010028980 Neoplasm Diseases 0.000 claims 3
- 210000001744 T-lymphocyte Anatomy 0.000 claims 3
- 201000011510 cancer Diseases 0.000 claims 3
- 239000012634 fragment Substances 0.000 claims 3
- 238000000338 in vitro Methods 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 108091008874 T cell receptors Proteins 0.000 claims 2
- 102000016266 T-Cell Antigen Receptors Human genes 0.000 claims 2
- 238000012258 culturing Methods 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 102100028704 Acetyl-CoA acetyltransferase, cytosolic Human genes 0.000 claims 1
- 125000001433 C-terminal amino-acid group Chemical group 0.000 claims 1
- 238000009007 Diagnostic Kit Methods 0.000 claims 1
- 102000025850 HLA-A2 Antigen Human genes 0.000 claims 1
- 108010074032 HLA-A2 Antigen Proteins 0.000 claims 1
- 101100536896 Homo sapiens ACAT2 gene Proteins 0.000 claims 1
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 claims 1
- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 claims 1
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 claims 1
- KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 claims 1
- 210000000612 antigen-presenting cell Anatomy 0.000 claims 1
- 210000001808 exosome Anatomy 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 229930182817 methionine Natural products 0.000 claims 1
- 125000001360 methionine group Chemical group N[C@@H](CCSC)C(=O)* 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 238000001356 surgical procedure Methods 0.000 claims 1
- 239000004474 valine Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32057710P | 2010-04-02 | 2010-04-02 | |
| US61/320,577 | 2010-04-02 | ||
| PCT/JP2011/001909 WO2011122022A1 (en) | 2010-04-02 | 2011-03-30 | Ect2 peptides and vaccines including the same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013523082A JP2013523082A (ja) | 2013-06-17 |
| JP2013523082A5 true JP2013523082A5 (enExample) | 2014-05-15 |
| JP5816965B2 JP5816965B2 (ja) | 2015-11-18 |
Family
ID=44711777
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012543839A Active JP5816965B2 (ja) | 2010-04-02 | 2011-03-30 | Ｅｃｔ２ペプチドおよびそれを含むワクチン |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US8951975B2 (enExample) |
| EP (1) | EP2553096B1 (enExample) |
| JP (1) | JP5816965B2 (enExample) |
| KR (1) | KR101863557B1 (enExample) |
| CN (1) | CN102939379B (enExample) |
| AR (1) | AR081065A1 (enExample) |
| AU (1) | AU2011233401B2 (enExample) |
| BR (1) | BR112012024997B1 (enExample) |
| CA (1) | CA2795318C (enExample) |
| CO (1) | CO6571869A2 (enExample) |
| DK (1) | DK2553096T3 (enExample) |
| EA (1) | EA027940B1 (enExample) |
| ES (1) | ES2655437T3 (enExample) |
| IL (1) | IL222057A (enExample) |
| MX (1) | MX342000B (enExample) |
| NZ (1) | NZ603379A (enExample) |
| SG (1) | SG184165A1 (enExample) |
| TW (2) | TWI538685B (enExample) |
| WO (1) | WO2011122022A1 (enExample) |
| ZA (1) | ZA201207342B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201507719D0 (en) * | 2015-05-06 | 2015-06-17 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides and scaffolds thereof for use in immunotherapy against colorectal carcinoma (CRC) and other cancers |
| GB201517538D0 (en) * | 2015-10-05 | 2015-11-18 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against small cell lung cancer and other cancers |
| PH12022551111A1 (en) | 2015-10-05 | 2023-08-23 | Immatics Biotechnologies Gmbh | Peptides and combination of peptides for use in immunotherapy against small cell lung cancer and other cancers |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0239102A3 (en) | 1986-03-28 | 1989-07-12 | Tsuji, Kimiyoshi | Process for the formation of human-human hybridoma |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US5108921A (en) | 1989-04-03 | 1992-04-28 | Purdue Research Foundation | Method for enhanced transmembrane transport of exogenous molecules |
| US5804566A (en) | 1993-08-26 | 1998-09-08 | The Regents Of The University Of California | Methods and devices for immunizing a host through administration of naked polynucleotides with encode allergenic peptides |
| US5679647A (en) | 1993-08-26 | 1997-10-21 | The Regents Of The University Of California | Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides |
| US5739118A (en) | 1994-04-01 | 1998-04-14 | Apollon, Inc. | Compositions and methods for delivery of genetic material |
| US5736524A (en) | 1994-11-14 | 1998-04-07 | Merck & Co.,. Inc. | Polynucleotide tuberculosis vaccine |
| EP0841945B1 (en) | 1995-08-03 | 2006-03-08 | Rijksuniversiteit te Leiden | Cell derived antigen presenting vesicles |
| US5853719A (en) | 1996-04-30 | 1998-12-29 | Duke University | Methods for treating cancers and pathogen infections using antigen-presenting cells loaded with RNA |
| JP2000516090A (ja) | 1996-07-26 | 2000-12-05 | スローン―ケッタリング インスティチュート フォー キャンサー リサーチ | 遺伝子的免疫化のための方法と試薬 |
| FR2766205B1 (fr) | 1997-07-16 | 2002-08-30 | Inst Nat Sante Rech Med | Nouveau procede de sensibilisation de cellules presentatrices d'antigene et nouveaux moyens pour la mise en oeuvre du procede |
| US7393663B2 (en) * | 1997-08-01 | 2008-07-01 | Serono Genetics Institute S.A. | Expressed sequence tags and encoded human proteins |
| US20030013649A1 (en) | 2000-01-31 | 2003-01-16 | Rosen Craig A. | Nucleic acids, proteins, and antibodies |
| EP1332153A4 (en) * | 2000-10-12 | 2006-01-11 | Exelixis Inc | HUMAN ECT2 AND METHOD OF USE THEREOF |
| US7919467B2 (en) * | 2000-12-04 | 2011-04-05 | Immunotope, Inc. | Cytotoxic T-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer |
| US7227007B2 (en) * | 2000-12-28 | 2007-06-05 | Asahi Kasei Pharma Corporation | NF-κB activating gene |
| EP2336167B1 (en) | 2001-03-14 | 2019-05-29 | Dako Denmark A/S | MHC molecule constructs and their uses for diagnosis and therapy |
| US20040236091A1 (en) | 2001-03-28 | 2004-11-25 | Chicz Roman M. | Translational profiling |
| WO2002096943A1 (en) * | 2001-05-25 | 2002-12-05 | Asahi Kasei Kabushiki Kaisha | Stat6-activating genes |
| US20030092616A1 (en) | 2001-05-25 | 2003-05-15 | Akio Matsuda | STAT6 activation gene |
| WO2002099062A2 (en) | 2001-06-04 | 2002-12-12 | Curagen Corporation | Novel antibodies that bind to antigenic polypeptides, nucleic acids encoding the antigens, and methods of use |
| CA2447935A1 (en) * | 2001-06-04 | 2002-12-12 | Curagen Corporation | Novel antibodies that bind to antigenic polypeptides, nucleic acids encoding the antigens, and methods of use |
| CA2399569A1 (en) | 2001-09-25 | 2003-03-25 | Yusuke Nakamura | Diagnostic markers and drug targets for treatment of cancer |
| GB2392158B (en) | 2002-08-21 | 2005-02-16 | Proimmune Ltd | Chimeric MHC protein and oligomer thereof |
| WO2005019258A2 (en) | 2003-08-11 | 2005-03-03 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
| JP4614952B2 (ja) | 2003-08-20 | 2011-01-19 | オンコセラピー・サイエンス株式会社 | 腎細胞癌（ｒｃｃ）の潜在的な新規治療標的としての低酸素誘導タンパク質２（ｈｉｇ２） |
| WO2006031221A1 (en) | 2004-09-13 | 2006-03-23 | Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Compositions comprising t cell receptors and methods of use thereof |
| US7998695B2 (en) | 2005-02-10 | 2011-08-16 | Oncotherapy Science, Inc. | Method of diagnosing bladder cancer |
| EP1907582B1 (en) | 2005-07-27 | 2012-01-04 | Oncotherapy Science, Inc. | Ect2 as a therapeutic target for esophageal cancer |
| EP2305811A1 (en) | 2005-07-27 | 2011-04-06 | Oncotherapy Science, Inc. | Method of diagnosing smal cell lung cancer |
| CN101287831B (zh) | 2005-09-13 | 2013-05-15 | 国立大学法人三重大学 | T细胞受体和编码该受体的核酸 |
| CN101432022A (zh) * | 2006-02-28 | 2009-05-13 | 肿瘤疗法科学股份有限公司 | 利用抗-EphA4抗体效应物作用损伤细胞的方法 |
| AU2007311946A1 (en) | 2006-10-20 | 2008-04-24 | Forerunner Pharma Research Co., Ltd. | Anti-cancer agent comprising anti-HB-EGF antibody as active ingredient |
| JP5378795B2 (ja) | 2006-10-20 | 2013-12-25 | 中外製薬株式会社 | 抗ｈｂ−ｅｇｆ抗体を有効成分として含む医薬組成物 |
| TWI494319B (zh) * | 2007-02-21 | 2015-08-01 | Oncotherapy Science Inc | 表現腫瘤相關抗原之癌症的胜肽疫苗 |
| EP2105511A1 (en) | 2008-03-28 | 2009-09-30 | Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung e.V. | Medicament compositions and substances for treatment and identifying adenocarcinoma of the lung |
| WO2010007791A1 (en) * | 2008-07-16 | 2010-01-21 | Oncotherapy Science, Inc. | Ect2 oncogene as a therapeutic target and prognostic indicator for lung and esophageal cancer |
| TW201008574A (en) * | 2008-08-19 | 2010-03-01 | Oncotherapy Science Inc | INHBB epitope peptides and vaccines containing the same |
-
2011
- 2011-03-23 TW TW100109936A patent/TWI538685B/zh not_active IP Right Cessation
- 2011-03-23 TW TW105112382A patent/TW201627003A/zh unknown
- 2011-03-30 JP JP2012543839A patent/JP5816965B2/ja active Active
- 2011-03-30 NZ NZ603379A patent/NZ603379A/en not_active IP Right Cessation
- 2011-03-30 DK DK11762265.4T patent/DK2553096T3/en active
- 2011-03-30 BR BR112012024997-5A patent/BR112012024997B1/pt not_active IP Right Cessation
- 2011-03-30 EP EP11762265.4A patent/EP2553096B1/en active Active
- 2011-03-30 SG SG2012069696A patent/SG184165A1/en unknown
- 2011-03-30 AU AU2011233401A patent/AU2011233401B2/en not_active Ceased
- 2011-03-30 US US13/638,272 patent/US8951975B2/en active Active
- 2011-03-30 MX MX2012011385A patent/MX342000B/es active IP Right Grant
- 2011-03-30 CN CN201180027360.5A patent/CN102939379B/zh not_active Expired - Fee Related
- 2011-03-30 KR KR1020127028426A patent/KR101863557B1/ko not_active Expired - Fee Related
- 2011-03-30 CA CA2795318A patent/CA2795318C/en active Active
- 2011-03-30 WO PCT/JP2011/001909 patent/WO2011122022A1/en not_active Ceased
- 2011-03-30 ES ES11762265.4T patent/ES2655437T3/es active Active
- 2011-03-30 EA EA201291004A patent/EA027940B1/ru not_active IP Right Cessation
- 2011-04-01 AR ARP110101103A patent/AR081065A1/es unknown
-
2012
- 2012-09-23 IL IL222057A patent/IL222057A/en active IP Right Grant
- 2012-10-01 ZA ZA2012/07342A patent/ZA201207342B/en unknown
- 2012-10-03 CO CO12173572A patent/CO6571869A2/es active IP Right Grant
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