JP2014506114A5 - - Google Patents
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- Publication number
- JP2014506114A5 JP2014506114A5 JP2013525055A JP2013525055A JP2014506114A5 JP 2014506114 A5 JP2014506114 A5 JP 2014506114A5 JP 2013525055 A JP2013525055 A JP 2013525055A JP 2013525055 A JP2013525055 A JP 2013525055A JP 2014506114 A5 JP2014506114 A5 JP 2014506114A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- peptide according
- group
- apc
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 108090000765 processed proteins & peptides Proteins 0.000 claims 33
- 210000000612 antigen-presenting cell Anatomy 0.000 claims 12
- 150000001413 amino acids Chemical class 0.000 claims 11
- 239000000427 antigen Substances 0.000 claims 11
- 102000036639 antigens Human genes 0.000 claims 11
- 108091007433 antigens Proteins 0.000 claims 11
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 claims 10
- 239000002157 polynucleotide Substances 0.000 claims 9
- 102000040430 polynucleotide Human genes 0.000 claims 9
- 108091033319 polynucleotide Proteins 0.000 claims 9
- 210000001744 T-lymphocyte Anatomy 0.000 claims 8
- 230000001939 inductive effect Effects 0.000 claims 6
- 238000000034 method Methods 0.000 claims 6
- 238000000338 in vitro Methods 0.000 claims 5
- 102000004196 processed proteins & peptides Human genes 0.000 claims 5
- 206010028980 Neoplasm Diseases 0.000 claims 4
- 201000011510 cancer Diseases 0.000 claims 4
- 210000004027 cell Anatomy 0.000 claims 4
- 238000012258 culturing Methods 0.000 claims 4
- 210000001808 exosome Anatomy 0.000 claims 4
- 239000012634 fragment Substances 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 3
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 claims 2
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 229920001184 polypeptide Polymers 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 125000001433 C-terminal amino-acid group Chemical group 0.000 claims 1
- 238000009007 Diagnostic Kit Methods 0.000 claims 1
- 102000025850 HLA-A2 Antigen Human genes 0.000 claims 1
- 108010074032 HLA-A2 Antigen Proteins 0.000 claims 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 claims 1
- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 claims 1
- KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 229930182817 methionine Natural products 0.000 claims 1
- 108091005601 modified peptides Proteins 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 230000002980 postoperative effect Effects 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
- 230000008685 targeting Effects 0.000 claims 1
- 239000004474 valine Substances 0.000 claims 1
- 239000013598 vector Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41918110P | 2010-12-02 | 2010-12-02 | |
| US61/419,181 | 2010-12-02 | ||
| PCT/JP2011/006551 WO2012073459A1 (en) | 2010-12-02 | 2011-11-25 | Tomm34 peptides and vaccines including the same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016121469A Division JP2016222676A (ja) | 2010-12-02 | 2016-06-20 | Ｔｏｍｍ３４ペプチドおよびそれを含むワクチン |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014506114A JP2014506114A (ja) | 2014-03-13 |
| JP2014506114A5 true JP2014506114A5 (enExample) | 2015-01-15 |
| JP6064186B2 JP6064186B2 (ja) | 2017-01-25 |
Family
ID=46171433
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013525055A Active JP6064186B2 (ja) | 2010-12-02 | 2011-11-25 | Ｔｏｍｍ３４ペプチドおよびそれを含むワクチン |
| JP2016121469A Withdrawn JP2016222676A (ja) | 2010-12-02 | 2016-06-20 | Ｔｏｍｍ３４ペプチドおよびそれを含むワクチン |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016121469A Withdrawn JP2016222676A (ja) | 2010-12-02 | 2016-06-20 | Ｔｏｍｍ３４ペプチドおよびそれを含むワクチン |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US9125849B2 (enExample) |
| EP (1) | EP2646546B1 (enExample) |
| JP (2) | JP6064186B2 (enExample) |
| KR (1) | KR102004900B1 (enExample) |
| CN (2) | CN103339253B (enExample) |
| AR (1) | AR084095A1 (enExample) |
| AU (1) | AU2011336019B2 (enExample) |
| BR (1) | BR112013013158B1 (enExample) |
| CA (1) | CA2819463C (enExample) |
| CO (1) | CO6862100A2 (enExample) |
| DK (1) | DK2646546T3 (enExample) |
| EA (1) | EA028216B1 (enExample) |
| ES (1) | ES2677118T3 (enExample) |
| IL (1) | IL226068B (enExample) |
| MX (1) | MX344586B (enExample) |
| MY (1) | MY166516A (enExample) |
| NZ (1) | NZ611361A (enExample) |
| PH (1) | PH12013501105A1 (enExample) |
| SG (2) | SG190407A1 (enExample) |
| TW (1) | TWI618541B (enExample) |
| UA (1) | UA110119C2 (enExample) |
| WO (1) | WO2012073459A1 (enExample) |
| ZA (1) | ZA201303886B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6283861B2 (ja) | 2012-09-11 | 2018-02-28 | オンコセラピー・サイエンス株式会社 | Ｕｂｅ２ｔペプチドおよびそれを含むワクチン |
| JP2015228191A (ja) * | 2014-06-03 | 2015-12-17 | カシオ計算機株式会社 | コンテンツ出力システム、コンテンツ出力方法、コンテンツ出力プログラム、および通信端末 |
| CN107534710B (zh) * | 2016-02-29 | 2019-07-23 | 京瓷办公信息系统株式会社 | 电子设备以及标记处理方法 |
| CN110191703B (zh) | 2017-01-25 | 2022-04-08 | 奥塞免疫疗法公司 | 用于肽递送的稳定乳液的制造方法 |
| CN117187267A (zh) * | 2022-10-20 | 2023-12-08 | 福州福瑞医学检验实验室有限公司 | Tomm34突变基因、检测其的引物、试剂盒和方法以及其用途 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5785973A (en) | 1988-02-01 | 1998-07-28 | Praxis Biologics, Inc. | Synthetic peptides representing a T-cell epitope as a carrier molecule for conjugate vaccines |
| DE69020143T2 (de) | 1989-02-17 | 1996-01-25 | Chiron Mimotopes Pty Ltd | Verfahren zur verwendung und herstellung von peptiden. |
| WO1994021808A1 (de) * | 1993-03-19 | 1994-09-29 | Boehringer Ingelheim International Gmbh | Verfahren zur herstellung von krebsvakzinen |
| US5840839A (en) | 1996-02-09 | 1998-11-24 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Alternative open reading frame DNA of a normal gene and a novel human cancer antigen encoded therein |
| WO2001049310A1 (en) | 2000-01-03 | 2001-07-12 | Argonex Pharmaceuticals, Inc. | C-ski oncogene-derived peptides for prevention, treatment, and diagnosis of cancer |
| US7700359B2 (en) | 2000-06-02 | 2010-04-20 | Novartis Vaccines And Diagnostics, Inc. | Gene products differentially expressed in cancerous cells |
| US20040181344A1 (en) | 2002-01-29 | 2004-09-16 | Massachusetts Institute Of Technology | Systems and methods for providing diagnostic services |
| WO2003104275A2 (en) * | 2002-06-06 | 2003-12-18 | Oncotherapy Science, Inc. | Genes and polypeptides relating to human colon cancers |
| TW200413406A (en) | 2002-08-26 | 2004-08-01 | Kirin Brewery | Peptides and drugs containing the same |
| EP2267023B1 (en) * | 2002-09-12 | 2015-02-11 | Oncotherapy Science, Inc. | KDR peptides and vaccines comprising the same |
| DE602004015064D1 (de) | 2003-01-06 | 2008-08-28 | Wyeth Corp | Zusammensetzungen und verfahren zur diagnose und behandlung von kolonkrebs |
| SI1620456T1 (sl) * | 2003-04-18 | 2014-05-30 | Biotech Synergy, Inc. | Hla-a2 s tumorjem povezan antigen peptidov in sestavki |
| JP5095603B2 (ja) * | 2005-07-27 | 2012-12-12 | オンコセラピー・サイエンス株式会社 | 結腸癌関連遺伝子ｔｏｍ３４ |
| SI1760089T1 (sl) * | 2005-09-05 | 2009-12-31 | Immatics Biotechnologies Gmbh | S tumorjem povezani peptidi, ki se veĹľejo na molekule humanega levkocitnega antigena (HLA) razreda I ali II in ustrezno cepivo proti raku |
| TWI494319B (zh) * | 2007-02-21 | 2015-08-01 | Oncotherapy Science Inc | 表現腫瘤相關抗原之癌症的胜肽疫苗 |
| TW201425333A (zh) * | 2007-04-11 | 2014-07-01 | Oncotherapy Science Inc | 腫瘤血管內皮標誌８胜肽及包含此胜肽之疫苗 |
| KR101744514B1 (ko) * | 2009-03-18 | 2017-06-08 | 온코세라피 사이언스 가부시키가이샤 | Ｎｅｉｌ3 펩티드 및 이를 포함하는 백신 |
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2011
- 2011-11-25 TW TW100143251A patent/TWI618541B/zh not_active IP Right Cessation
- 2011-11-25 BR BR112013013158-6A patent/BR112013013158B1/pt not_active IP Right Cessation
- 2011-11-25 EP EP11846000.5A patent/EP2646546B1/en active Active
- 2011-11-25 AU AU2011336019A patent/AU2011336019B2/en not_active Ceased
- 2011-11-25 KR KR1020137017079A patent/KR102004900B1/ko not_active Expired - Fee Related
- 2011-11-25 ES ES11846000.5T patent/ES2677118T3/es active Active
- 2011-11-25 CN CN201180066777.2A patent/CN103339253B/zh not_active Expired - Fee Related
- 2011-11-25 JP JP2013525055A patent/JP6064186B2/ja active Active
- 2011-11-25 SG SG2013040415A patent/SG190407A1/en unknown
- 2011-11-25 NZ NZ61136111A patent/NZ611361A/en not_active IP Right Cessation
- 2011-11-25 CN CN201510490693.1A patent/CN105111281A/zh active Pending
- 2011-11-25 CA CA2819463A patent/CA2819463C/en active Active
- 2011-11-25 MX MX2013006014A patent/MX344586B/es active IP Right Grant
- 2011-11-25 WO PCT/JP2011/006551 patent/WO2012073459A1/en not_active Ceased
- 2011-11-25 SG SG10201509823WA patent/SG10201509823WA/en unknown
- 2011-11-25 PH PH1/2013/501105A patent/PH12013501105A1/en unknown
- 2011-11-25 UA UAA201307324A patent/UA110119C2/uk unknown
- 2011-11-25 DK DK11846000.5T patent/DK2646546T3/en active
- 2011-11-25 US US13/990,766 patent/US9125849B2/en active Active
- 2011-11-25 MY MYPI2013700903A patent/MY166516A/en unknown
- 2011-11-25 EA EA201390811A patent/EA028216B1/ru not_active IP Right Cessation
- 2011-12-02 AR ARP110104514A patent/AR084095A1/es unknown
-
2013
- 2013-04-30 IL IL226068A patent/IL226068B/en active IP Right Grant
- 2013-05-28 ZA ZA2013/03886A patent/ZA201303886B/en unknown
- 2013-07-02 CO CO13155530A patent/CO6862100A2/es active IP Right Grant
-
2015
- 2015-07-27 US US14/810,287 patent/US9585948B2/en not_active Expired - Fee Related
-
2016
- 2016-06-20 JP JP2016121469A patent/JP2016222676A/ja not_active Withdrawn
-
2017
- 2017-01-23 US US15/412,760 patent/US20170198010A1/en not_active Abandoned