JP2013518244A5 - - Google Patents
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- Publication number
- JP2013518244A5 JP2013518244A5 JP2012549374A JP2012549374A JP2013518244A5 JP 2013518244 A5 JP2013518244 A5 JP 2013518244A5 JP 2012549374 A JP2012549374 A JP 2012549374A JP 2012549374 A JP2012549374 A JP 2012549374A JP 2013518244 A5 JP2013518244 A5 JP 2013518244A5
- Authority
- JP
- Japan
- Prior art keywords
- female
- pgf2α
- pge2
- compound
- prostaglandin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- PXGPLTODNUVGFL-BRIYLRKRSA-N (E,Z)-(1R,2R,3R,5S)-7-(3,5-Dihydroxy-2-((3S)-(3-hydroxy-1-octenyl))cyclopentyl)-5-heptenoic acid Chemical compound CCCCC[C@H](O)C=C[C@H]1[C@H](O)C[C@H](O)[C@@H]1CC=CCCCC(O)=O PXGPLTODNUVGFL-BRIYLRKRSA-N 0.000 claims 12
- XEYBRNLFEZDVAW-ARSRFYASSA-N dinoprostone Chemical compound CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O XEYBRNLFEZDVAW-ARSRFYASSA-N 0.000 claims 10
- 230000002357 endometrial effect Effects 0.000 claims 9
- 238000000034 method Methods 0.000 claims 9
- 229960002986 dinoprostone Drugs 0.000 claims 8
- XEYBRNLFEZDVAW-UHFFFAOYSA-N prostaglandin E2 Natural products CCCCCC(O)C=CC1C(O)CC(=O)C1CC=CCCCC(O)=O XEYBRNLFEZDVAW-UHFFFAOYSA-N 0.000 claims 8
- 150000001875 compounds Chemical class 0.000 claims 7
- 239000012530 fluid Substances 0.000 claims 4
- 239000000523 sample Substances 0.000 claims 4
- 230000032692 embryo implantation Effects 0.000 claims 3
- 239000013074 reference sample Substances 0.000 claims 3
- 239000003433 contraceptive agent Substances 0.000 claims 2
- 230000002254 contraceptive effect Effects 0.000 claims 2
- 230000002708 enhancing effect Effects 0.000 claims 2
- 230000036512 infertility Effects 0.000 claims 2
- 208000000509 infertility Diseases 0.000 claims 2
- 231100000535 infertility Toxicity 0.000 claims 2
- 150000002632 lipids Chemical class 0.000 claims 2
- PXGPLTODNUVGFL-UHFFFAOYSA-N prostaglandin F2alpha Natural products CCCCCC(O)C=CC1C(O)CC(O)C1CC=CCCCC(O)=O PXGPLTODNUVGFL-UHFFFAOYSA-N 0.000 claims 2
- 150000003180 prostaglandins Chemical class 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 230000004720 fertilization Effects 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 238000004811 liquid chromatography Methods 0.000 claims 1
- 210000001161 mammalian embryo Anatomy 0.000 claims 1
- 230000035800 maturation Effects 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 claims 1
- 230000035935 pregnancy Effects 0.000 claims 1
- 238000004885 tandem mass spectrometry Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10382011.4 | 2010-01-21 | ||
| EP10382011A EP2348318A1 (en) | 2010-01-21 | 2010-01-21 | Diagnostic method for endometrial receptivity |
| PCT/EP2011/050867 WO2011089240A1 (en) | 2010-01-21 | 2011-01-21 | Diagnostic method for endometrial receptivity |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013518244A JP2013518244A (ja) | 2013-05-20 |
| JP2013518244A5 true JP2013518244A5 (https=) | 2014-03-06 |
| JP5732664B2 JP5732664B2 (ja) | 2015-06-10 |
Family
ID=42200845
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012549374A Expired - Fee Related JP5732664B2 (ja) | 2010-01-21 | 2011-01-21 | 子宮内膜受容性の診断方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20130144114A1 (https=) |
| EP (2) | EP2348318A1 (https=) |
| JP (1) | JP5732664B2 (https=) |
| CN (1) | CN102792166B (https=) |
| BR (1) | BR112012018289A2 (https=) |
| CA (1) | CA2787582A1 (https=) |
| DK (1) | DK2526425T3 (https=) |
| ES (1) | ES2485847T3 (https=) |
| PL (1) | PL2526425T3 (https=) |
| WO (1) | WO2011089240A1 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010010201A1 (es) | 2008-07-22 | 2010-01-28 | Equipo Ivi Investigacion Sl | Perfil de expresion genetica como marcador de la receptividad endometrial |
| US9107696B2 (en) * | 2008-08-06 | 2015-08-18 | Emory University | Method of embryo transfer that eliminates transferred air while hormonally inducing implantation and apparatus |
| PL2827150T3 (pl) | 2009-08-22 | 2021-05-31 | The Board Of Trustees Of The Leland Stanford Junior University | Obrazowanie i ocena zarodków, oocytów i komórek macierzystych |
| CA2812776C (en) | 2010-09-27 | 2022-05-17 | Auxogyn, Inc. | Apparatus, method, and system for the automated imaging and evaluation of embryos, oocytes, and stem cells |
| CA2827945C (en) | 2011-02-23 | 2021-10-12 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of detecting aneuploidy in human embryos |
| WO2013135836A1 (en) * | 2012-03-14 | 2013-09-19 | Centre Hospitalier Universitaire Pontchaillou | Itih5 as a diagnostic marker of uterine development and functional defects |
| EP2687851A1 (en) | 2012-07-20 | 2014-01-22 | Matricelab Innove | Method for increasing implantation success in assisted fertilization |
| US10241108B2 (en) | 2013-02-01 | 2019-03-26 | Ares Trading S.A. | Abnormal syngamy phenotypes observed with time lapse imaging for early identification of embryos with lower development potential |
| RU2562559C1 (ru) * | 2014-05-27 | 2015-09-10 | Федеральное государственное бюджетное учреждение "Научно-исследовательский институт акушерства и гинекологии им. Д.О. Отта" Северо-Западного отделения Российской академии медицинских наук | Способ прогнозирования рецептивности эндометрия в циклах экстракорпорального оплодотворения |
| US11129851B2 (en) | 2014-06-17 | 2021-09-28 | Igenomix S.L. | Stem cell therapy in endometrial pathologies |
| CN105486799B (zh) * | 2016-01-25 | 2017-12-01 | 中国药科大学 | 用于诊断急性冠脉综合征的代谢标志物 |
| CN105445408B (zh) * | 2016-01-25 | 2018-06-12 | 齐炼文 | 诊断区分冠状动脉粥样硬化和稳定型心绞痛的代谢标志物 |
| EP3545107A2 (en) * | 2016-11-22 | 2019-10-02 | Quantbio Kft | Determination of the receptive status of the endometrium |
| RU2651762C1 (ru) * | 2017-06-14 | 2018-04-23 | Федеральное государственное бюджетное учреждение "Уральский научно-исследовательский институт охраны материнства и младенчества" Министерства здравоохранения Российской Федерации (ФГБУ "НИИ ОММ" Минздрава России) | Способ оценки рецептивности эндометрия в период "имплантационного окна" |
| EP3569718A1 (en) * | 2018-05-16 | 2019-11-20 | Integrated Genetic Lab Services SLU | Kit and method for determining the receptivity status of an endometrium |
| EP3914915A1 (en) * | 2019-01-25 | 2021-12-01 | Fertility Lab Sciences, LLC | Uterine endometrial fluid for prediction of success in fertility treatment |
| WO2020160612A1 (en) * | 2019-02-05 | 2020-08-13 | The University Of Sydney | Uterine receptivity |
| EP3779455A1 (en) * | 2019-08-14 | 2021-02-17 | Asociación Centro de Investigación Cooperativa en Biociencias - CIC bioGUNE | Lipid signatures for determining the outcome of embryo implantation during in vitro fertilization |
| CN111505312A (zh) * | 2020-04-30 | 2020-08-07 | 深圳市锦欣医疗科技创新中心有限公司 | 一组子宫内膜受容性的生物标志物、其筛选方法及应用 |
| CN111505311A (zh) * | 2020-04-30 | 2020-08-07 | 深圳市锦欣医疗科技创新中心有限公司 | 一组胚胎反复种植失败的生物标志物、其筛选方法及应用 |
| TWI791347B (zh) * | 2020-12-11 | 2023-02-01 | 酷氏基因生物科技股份有限公司 | 一種用於評估胚胎植入成功率的預測方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05501541A (ja) * | 1989-05-05 | 1993-03-25 | ノーザン シドニー エリア ヘルス サーヴィス | 繁殖力増強 |
| GB0201284D0 (en) | 2002-01-21 | 2002-03-06 | Isis Innovation | Screening methods for contraceptive and fertility agents |
| EP1511863A4 (en) * | 2002-05-14 | 2006-12-27 | Univ Leland Stanford Junior | ENDOMETRIAL GENES FOR THE DETECTION OF ENDOMETRIAL DISORDERS |
| DE10236405A1 (de) * | 2002-08-02 | 2004-02-19 | Schering Ag | Progesteronrezeptormodulatoren mit erhöhter antigonadotroper Aktivität für die weibliche Fertilitätskontrolle und Hormonersatztherapie |
| ES2273061T3 (es) * | 2002-08-02 | 2007-05-01 | Schering Aktiengesellschaft | Agentes moduladores de receptores de progesterona con actividad antigonadotropa elevada para el control de fertilidad femenina y para la terapia por reemplazo hormonal. |
| CN1863905A (zh) * | 2003-09-08 | 2006-11-15 | 得克萨斯系统大学董事会 | 通过用前列腺素或前列腺素类似物补充培养基加强体外胚发育的方法以及组合物 |
| EP1765083A4 (en) * | 2004-05-28 | 2008-08-20 | Serono Lab | USE OF IL-17 TO TREAT FERTILITY DISORDERS |
| JP2007278750A (ja) * | 2006-04-04 | 2007-10-25 | Ono Pharmaceut Co Ltd | プロスタグランジン類及びその類縁体の定量方法 |
-
2010
- 2010-01-21 EP EP10382011A patent/EP2348318A1/en not_active Withdrawn
-
2011
- 2011-01-21 BR BR112012018289-7A patent/BR112012018289A2/pt not_active IP Right Cessation
- 2011-01-21 PL PL11700679T patent/PL2526425T3/pl unknown
- 2011-01-21 WO PCT/EP2011/050867 patent/WO2011089240A1/en not_active Ceased
- 2011-01-21 JP JP2012549374A patent/JP5732664B2/ja not_active Expired - Fee Related
- 2011-01-21 CN CN201180010375.0A patent/CN102792166B/zh not_active Expired - Fee Related
- 2011-01-21 EP EP11700679.1A patent/EP2526425B1/en not_active Not-in-force
- 2011-01-21 US US13/574,291 patent/US20130144114A1/en not_active Abandoned
- 2011-01-21 CA CA2787582A patent/CA2787582A1/en not_active Abandoned
- 2011-01-21 DK DK11700679.1T patent/DK2526425T3/da active
- 2011-01-21 ES ES11700679.1T patent/ES2485847T3/es active Active
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