AR060120A1 - Medio y metodo para diagnosticar la diabetes - Google Patents
Medio y metodo para diagnosticar la diabetesInfo
- Publication number
- AR060120A1 AR060120A1 ARP070101229A ARP070101229A AR060120A1 AR 060120 A1 AR060120 A1 AR 060120A1 AR P070101229 A ARP070101229 A AR P070101229A AR P070101229 A ARP070101229 A AR P070101229A AR 060120 A1 AR060120 A1 AR 060120A1
- Authority
- AR
- Argentina
- Prior art keywords
- diabetes
- predisposition
- metabolite
- acid
- metabolites
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
- Y10T436/144444—Glucose
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Endocrinology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Un método para diagnosticar la diabetes o una predisposicion a ésta que comprende determinar por lo menos un metabolito en una muestra de ensayo de un sujeto sospechado de sufrir diabetes o de tener una predisposicion a ésta y comparar dicho por lo menos un metabolito con una referencia, por la cual la diabetes o una predisposicion a ésta debe diagnosticarse. Un conjunto de metabolitos, un conjunto de datos que comprenden valores característicos de los metabolitos y un medio de almacenamiento que comprende dicho conjunto de datos. Además, un sistema que comprende medios para comparar valores característicos de los metabolitos de una muestra ligada en forma funcional a un medio de almacenamiento de datos. Adicionalmente, medios de diagnostico que comprenden por lo menos un metabolito y el uso de dicho por lo menos un metabolito para la fabricacion de medios de diagnostico para diagnosticar la diabetes. Finalmente, un método para identificar metabolitos relacionados con la diabetes. Reivindicacion 1: Un método para diagnosticar la diabetes o una predisposicion a ésta caracterizado porque comprende: (a) determinar por lo menos un metabolito en una muestra de ensayo de un sujeto sospechado de sufrir diabetes o de tener una predisposicion a ésta, dicho por lo menos un metabolito se selecciona del grupo formado por: 1,5-anhidrosorbitol, ácido eicosenoico (C20:1), eritrol, ácido ribonico, ácido tricosanoico (C23:0), pentadecanol, campesterol, ácido maleico y ácido melísico (C30:0); y (b) comparar los resultados de las pruebas de la determinacion del paso (a) con una referencia, por la cual la diabetes o una predisposicion a ésta debe diagnosticarse.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06111705A EP1837657A1 (en) | 2006-03-24 | 2006-03-24 | Means and method for predicting or diagnosing diabetes |
EP06120273 | 2006-09-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR060120A1 true AR060120A1 (es) | 2008-05-28 |
Family
ID=38016918
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP070101230A AR060121A1 (es) | 2006-03-24 | 2007-03-23 | Medio y metodo para predecir la diabetes |
ARP070101229A AR060120A1 (es) | 2006-03-24 | 2007-03-23 | Medio y metodo para diagnosticar la diabetes |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP070101230A AR060121A1 (es) | 2006-03-24 | 2007-03-23 | Medio y metodo para predecir la diabetes |
Country Status (10)
Country | Link |
---|---|
US (2) | US8216847B2 (es) |
EP (6) | EP2330423B1 (es) |
JP (4) | JP5167239B2 (es) |
CN (1) | CN101438168B (es) |
AR (2) | AR060121A1 (es) |
AT (2) | ATE493661T1 (es) |
CA (2) | CA2647122A1 (es) |
DE (2) | DE602007011592D1 (es) |
ES (4) | ES2522818T3 (es) |
WO (2) | WO2007110358A2 (es) |
Families Citing this family (43)
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JP5167239B2 (ja) * | 2006-03-24 | 2013-03-21 | メタノミクス ゲーエムベーハー | 糖尿病の検出手段および検出方法 |
ES2443540T3 (es) | 2007-07-17 | 2014-02-19 | Metabolon, Inc. | Biomarcadores para pre-diabetes y métodos que usan los mismos |
JPWO2009054350A1 (ja) * | 2007-10-25 | 2011-03-03 | 味の素株式会社 | 耐糖能異常の評価方法、耐糖能異常評価装置、耐糖能異常評価方法、耐糖能異常評価システム、耐糖能異常評価プログラムおよび記録媒体、ならびに耐糖能異常の予防・改善物質の探索方法 |
WO2009153131A1 (en) * | 2008-05-28 | 2009-12-23 | Basf Se | Means and methods for assessing liver enzyme induction |
US8597875B2 (en) | 2008-05-28 | 2013-12-03 | Basf Se | Method for diagnosing liver toxicity with sex specific biomarkers |
US8658427B2 (en) | 2008-05-28 | 2014-02-25 | Basf Se | Means and methods for assessing increased peroxisomal proliferation |
CA2727855A1 (en) * | 2008-07-15 | 2010-01-21 | Metanomics Health Gmbh | Means and methods diagnosing gastric bypass and conditions related thereto |
DE102009013914B4 (de) * | 2009-03-19 | 2011-05-05 | Bruker Daltonik Gmbh | Kalibriersubstanzen für Atmosphärendruck-Ionenquellen |
WO2010109192A1 (en) | 2009-03-24 | 2010-09-30 | Anamar Ab | Metabolic profiles |
EP2438445B1 (en) * | 2009-06-04 | 2014-07-16 | Metanomics Health GmbH | Methods for diagnosing prostate carcinomas |
EP2464966A1 (en) * | 2009-08-13 | 2012-06-20 | Basf Se | Means and methods for diagnosingthyroid disorders |
US8367359B1 (en) * | 2009-10-23 | 2013-02-05 | The United States Of America, As Represented By The Secretary Of Agriculture | Metabolic biomarkers for diabetes and insulin resistance |
ES2728120T3 (es) * | 2010-01-29 | 2019-10-22 | Metanomics Gmbh | Medios y procedimientos para diagnosticar insuficiencia cardíaca en un sujeto |
WO2012013667A1 (en) * | 2010-07-30 | 2012-02-02 | Technische Universität Graz | Analyses of analytes by mass spectrometry with values in at least 3 dimensions |
WO2012051463A2 (en) * | 2010-10-14 | 2012-04-19 | The Regents Of The University Of California | Urine metabolomic profile of diabetic kidney disease |
AU2011346553A1 (en) * | 2010-12-23 | 2013-07-11 | Metanomics Health Gmbh | Means and method for predicting diabetes |
US20130101984A1 (en) * | 2011-10-20 | 2013-04-25 | The Washington University | Methods of detecting sleepiness |
WO2013132460A2 (en) * | 2012-03-09 | 2013-09-12 | Basf Se | Means and methods for assessing disorders related to impaired iron adsorption or energy metabolism |
US9470771B2 (en) | 2012-06-08 | 2016-10-18 | Liposcience, Inc. | NMR measurements of NMR biomarker GlycA |
US9361429B2 (en) | 2012-06-08 | 2016-06-07 | Liposcience, Inc. | Multi-parameter diabetes risk evaluations |
US9928345B2 (en) | 2012-06-08 | 2018-03-27 | Liposciences, Inc. | Multiple-marker risk parameters predictive of conversion to diabetes |
EP2867669B1 (en) | 2012-06-27 | 2016-12-21 | Metanomics Health GmbH | Methods for identifying diabetes drugs |
WO2014060486A1 (en) | 2012-10-18 | 2014-04-24 | Metanomics Gmbh | Means and methods for determining a clearance normalized amount of a metabolite disease biomarker in a sample |
EP3321686B1 (en) * | 2013-01-31 | 2024-03-13 | Metabolon, Inc. | Biomarkers related to insulin resistance progression and methods using the same |
KR102204498B1 (ko) * | 2013-04-09 | 2021-01-19 | 아지노모토 가부시키가이샤 | 생활습관병 지표의 평가 방법, 생활습관병 지표 평가 장치, 생활습관병 지표 평가 방법, 생활습관병 지표 평가 프로그램 제품, 생활습관병 지표 평가 시스템, 및 정보통신 단말장치 |
CN103616465A (zh) * | 2013-10-28 | 2014-03-05 | 浙江大学 | 血液相关脂肪酸谱的建立方法 |
US20150323520A1 (en) * | 2014-05-07 | 2015-11-12 | The Trustees Of The Stevens Institute Of Technology | Diagnosis of kidney transplant acute rejection |
JP6773951B2 (ja) * | 2014-05-30 | 2020-10-21 | 学校法人東京医科大学 | 唾液試料の調製方法 |
WO2016138232A1 (en) * | 2015-02-26 | 2016-09-01 | Wisconsin Alumni Research Foundation | Methods for predicting glucoregulatory dysfunction |
WO2017003166A1 (ko) * | 2015-06-29 | 2017-01-05 | 고려대학교 산학협력단 | 대사체 분석을 이용한 당뇨병 조기 진단용 조성물 |
CN106979982B (zh) * | 2016-01-19 | 2021-01-05 | 上海市第六人民医院 | 一种用于糖尿病风险预测、治疗评价的方法及试剂盒 |
CN105784829A (zh) * | 2016-04-06 | 2016-07-20 | 深圳市老年医学研究所 | 2型糖尿病肾虚证唾液蛋白指纹图谱分子诊断模型建立方法 |
CN105699663A (zh) * | 2016-04-06 | 2016-06-22 | 深圳市老年医学研究所 | 2型糖尿病唾液蛋白指纹图谱分子诊断模型建立方法 |
SG11201810254UA (en) * | 2016-05-17 | 2018-12-28 | Univ Osaka | Blood sample analysis method and system, for determining diabetes |
US20200033360A1 (en) * | 2017-03-31 | 2020-01-30 | Metabolon, Inc. | Comprehensive and quantitative lipid and tocopherol analysis |
JP7197555B2 (ja) * | 2017-08-17 | 2022-12-27 | ソシエテ・デ・プロデュイ・ネスレ・エス・アー | 思春期前の小児期前糖尿病のマーカー |
CN108362804B (zh) * | 2018-02-27 | 2019-01-29 | 山东英盛生物技术有限公司 | 一种检测血液样品中dha含量的方法及试剂盒 |
CN109507337B (zh) * | 2018-12-29 | 2022-02-22 | 上海交通大学医学院附属新华医院 | 一种基于血尿中代谢产物预测甘地胶囊治疗糖尿病肾病机制的新方法 |
CN111443143B (zh) * | 2020-04-30 | 2022-04-29 | 宁波市产品食品质量检验研究院(宁波市纤维检验所) | 一种快速测定乳粉中胆固醇含量的方法 |
CN114216851A (zh) * | 2020-11-27 | 2022-03-22 | 四川大学华西医院 | 一种基于表面增强拉曼光谱技术的急性胰腺炎评估装置 |
KR102583808B1 (ko) * | 2021-03-05 | 2023-09-26 | 경희대학교 산학협력단 | 눈물을 이용한 당뇨병의 진단 방법 및 키트 |
CN114324662B (zh) * | 2021-12-30 | 2022-09-16 | 中南大学 | 用于诊断或预防糖尿病的血清生物标志物的应用 |
CN114965753A (zh) * | 2022-05-13 | 2022-08-30 | 重庆医科大学附属第一医院 | 一种lgals3bp蛋白丰度检测试剂在制备妊娠期糖尿病泪液诊断试剂中的应用 |
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2007
- 2007-03-21 JP JP2009500865A patent/JP5167239B2/ja not_active Expired - Fee Related
- 2007-03-21 ES ES10196650.5T patent/ES2522818T3/es active Active
- 2007-03-21 CN CN2007800162752A patent/CN101438168B/zh not_active Expired - Fee Related
- 2007-03-21 EP EP10196430.2A patent/EP2330423B1/en not_active Not-in-force
- 2007-03-21 AT AT07727168T patent/ATE493661T1/de active
- 2007-03-21 EP EP07727168A patent/EP2008108B1/en not_active Not-in-force
- 2007-03-21 DE DE602007011592T patent/DE602007011592D1/de active Active
- 2007-03-21 WO PCT/EP2007/052692 patent/WO2007110358A2/en active Application Filing
- 2007-03-21 AT AT07727167T patent/ATE493660T1/de active
- 2007-03-21 ES ES10196649.7T patent/ES2522816T3/es active Active
- 2007-03-21 US US12/293,587 patent/US8216847B2/en not_active Expired - Fee Related
- 2007-03-21 JP JP2009500866A patent/JP5199994B2/ja not_active Expired - Fee Related
- 2007-03-21 DE DE602007011588T patent/DE602007011588D1/de active Active
- 2007-03-21 EP EP10196643.0A patent/EP2369346B1/en not_active Not-in-force
- 2007-03-21 CA CA002647122A patent/CA2647122A1/en not_active Abandoned
- 2007-03-21 ES ES10196430.2T patent/ES2525345T3/es active Active
- 2007-03-21 EP EP07727167A patent/EP2005189B1/en not_active Not-in-force
- 2007-03-21 CA CA002647197A patent/CA2647197A1/en not_active Abandoned
- 2007-03-21 ES ES10196643.0T patent/ES2522815T3/es active Active
- 2007-03-21 US US12/293,598 patent/US8216848B2/en not_active Expired - Fee Related
- 2007-03-21 EP EP10196650.5A patent/EP2339346B1/en not_active Not-in-force
- 2007-03-21 WO PCT/EP2007/052691 patent/WO2007110357A2/en active Application Filing
- 2007-03-21 EP EP10196649.7A patent/EP2336782B1/en not_active Not-in-force
- 2007-03-23 AR ARP070101230A patent/AR060121A1/es not_active Application Discontinuation
- 2007-03-23 AR ARP070101229A patent/AR060120A1/es unknown
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2012
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