CN102792166B - 子宫内膜接受性的诊断方法 - Google Patents
子宫内膜接受性的诊断方法 Download PDFInfo
- Publication number
- CN102792166B CN102792166B CN201180010375.0A CN201180010375A CN102792166B CN 102792166 B CN102792166 B CN 102792166B CN 201180010375 A CN201180010375 A CN 201180010375A CN 102792166 B CN102792166 B CN 102792166B
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- CN
- China
- Prior art keywords
- endometrium
- pge2
- pgf2
- female mammal
- woman
- Prior art date
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/42—Gynaecological or obstetrical instruments or methods
- A61B17/425—Gynaecological or obstetrical instruments or methods for reproduction or fertilisation
- A61B17/435—Gynaecological or obstetrical instruments or methods for reproduction or fertilisation for embryo or ova transplantation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/88—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving prostaglandins or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
- G01N2800/367—Infertility, e.g. sperm disorder, ovulatory dysfunction
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/104165—Lipid, cholesterol, or triglyceride standard or control
Abstract
Description
Claims (4)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP10382011.4 | 2010-01-21 | ||
EP10382011A EP2348318A1 (en) | 2010-01-21 | 2010-01-21 | Diagnostic method for endometrial receptivity |
PCT/EP2011/050867 WO2011089240A1 (en) | 2010-01-21 | 2011-01-21 | Diagnostic method for endometrial receptivity |
Publications (2)
Publication Number | Publication Date |
---|---|
CN102792166A CN102792166A (zh) | 2012-11-21 |
CN102792166B true CN102792166B (zh) | 2015-10-21 |
Family
ID=42200845
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201180010375.0A Expired - Fee Related CN102792166B (zh) | 2010-01-21 | 2011-01-21 | 子宫内膜接受性的诊断方法 |
Country Status (11)
Country | Link |
---|---|
US (1) | US20130144114A1 (zh) |
EP (2) | EP2348318A1 (zh) |
JP (1) | JP5732664B2 (zh) |
CN (1) | CN102792166B (zh) |
BR (1) | BR112012018289A2 (zh) |
CA (1) | CA2787582A1 (zh) |
DK (1) | DK2526425T3 (zh) |
ES (1) | ES2485847T3 (zh) |
HK (1) | HK1177636A1 (zh) |
PL (1) | PL2526425T3 (zh) |
WO (1) | WO2011089240A1 (zh) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010010201A1 (es) | 2008-07-22 | 2010-01-28 | Equipo Ivi Investigacion Sl | Perfil de expresion genetica como marcador de la receptividad endometrial |
US9107696B2 (en) * | 2008-08-06 | 2015-08-18 | Emory University | Method of embryo transfer that eliminates transferred air while hormonally inducing implantation and apparatus |
CN104293646A (zh) | 2009-08-22 | 2015-01-21 | 里兰斯坦福初级大学理事会 | 成像并评估胚胎、卵母细胞和干细胞 |
CA2812776C (en) | 2010-09-27 | 2022-05-17 | Auxogyn, Inc. | Apparatus, method, and system for the automated imaging and evaluation of embryos, oocytes, and stem cells |
WO2012116185A1 (en) | 2011-02-23 | 2012-08-30 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of detecting aneuploidy in human embryos |
EP2825892A1 (en) * | 2012-03-14 | 2015-01-21 | Centre Hospitalier Universitaire Pontchaillou | Itih5 as a diagnostic marker of uterine development and functional defects |
EP2687851A1 (en) | 2012-07-20 | 2014-01-22 | Matricelab Innove | Method for increasing implantation success in assisted fertilization |
ES2755878T3 (es) | 2013-02-01 | 2020-04-24 | Ares Trading Sa | Fenotipos anormales de singamia observados con obtención de imágenes a intervalos de tiempo preestablecidos para identificación precoz de embriones con potencial de desarrollo inferior |
RU2562559C1 (ru) * | 2014-05-27 | 2015-09-10 | Федеральное государственное бюджетное учреждение "Научно-исследовательский институт акушерства и гинекологии им. Д.О. Отта" Северо-Западного отделения Российской академии медицинских наук | Способ прогнозирования рецептивности эндометрия в циклах экстракорпорального оплодотворения |
EP4012023B1 (en) | 2014-06-17 | 2024-05-15 | Asherman Therapy, S.L. | Stem cell therapy in endometrial pathologies |
CN105445408B (zh) * | 2016-01-25 | 2018-06-12 | 齐炼文 | 诊断区分冠状动脉粥样硬化和稳定型心绞痛的代谢标志物 |
CN105486799B (zh) * | 2016-01-25 | 2017-12-01 | 中国药科大学 | 用于诊断急性冠脉综合征的代谢标志物 |
WO2018096375A2 (en) * | 2016-11-22 | 2018-05-31 | Quantbio Kft | Method for determining the receptive status of endometrium |
RU2651762C1 (ru) * | 2017-06-14 | 2018-04-23 | Федеральное государственное бюджетное учреждение "Уральский научно-исследовательский институт охраны материнства и младенчества" Министерства здравоохранения Российской Федерации (ФГБУ "НИИ ОММ" Минздрава России) | Способ оценки рецептивности эндометрия в период "имплантационного окна" |
EP3569718A1 (en) * | 2018-05-16 | 2019-11-20 | Integrated Genetic Lab Services SLU | Kit and method for determining the receptivity status of an endometrium |
CN113490753A (zh) * | 2019-01-25 | 2021-10-08 | 生育实验室科学有限责任公司 | 用于预测生育治疗成功的子宫内膜液 |
WO2020160612A1 (en) * | 2019-02-05 | 2020-08-13 | The University Of Sydney | Uterine receptivity |
EP3779455A1 (en) * | 2019-08-14 | 2021-02-17 | Asociación Centro de Investigación Cooperativa en Biociencias - CIC bioGUNE | Lipid signatures for determining the outcome of embryo implantation during in vitro fertilization |
CN111505311A (zh) * | 2020-04-30 | 2020-08-07 | 深圳市锦欣医疗科技创新中心有限公司 | 一组胚胎反复种植失败的生物标志物、其筛选方法及应用 |
CN111505312A (zh) * | 2020-04-30 | 2020-08-07 | 深圳市锦欣医疗科技创新中心有限公司 | 一组子宫内膜受容性的生物标志物、其筛选方法及应用 |
US20220186312A1 (en) * | 2020-12-11 | 2022-06-16 | Guzip Biomarkers Corporation | Predictive method for assessing the success of embryo implantation |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05501541A (ja) * | 1989-05-05 | 1993-03-25 | ノーザン シドニー エリア ヘルス サーヴィス | 繁殖力増強 |
GB0201284D0 (en) | 2002-01-21 | 2002-03-06 | Isis Innovation | Screening methods for contraceptive and fertility agents |
WO2004061074A2 (en) * | 2002-05-14 | 2004-07-22 | The Board Of Trustees Of The Leland Stanford Junior University | Endometrial genes in endometrial disorders |
ES2273061T3 (es) * | 2002-08-02 | 2007-05-01 | Schering Aktiengesellschaft | Agentes moduladores de receptores de progesterona con actividad antigonadotropa elevada para el control de fertilidad femenina y para la terapia por reemplazo hormonal. |
DE10236405A1 (de) * | 2002-08-02 | 2004-02-19 | Schering Ag | Progesteronrezeptormodulatoren mit erhöhter antigonadotroper Aktivität für die weibliche Fertilitätskontrolle und Hormonersatztherapie |
JP2007504807A (ja) * | 2003-09-08 | 2007-03-08 | ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム | 培養培地にプロスタグランジン又はプロスタグランジン類似物を補足することによってインビトロ胚発生を高めるための方法及び組成 |
US20080014172A1 (en) * | 2004-05-28 | 2008-01-17 | Applied Research Systems Ars Holding N.V. | Use of Il-17 in the Treatment of Fertility-Related Disorders |
JP2007278750A (ja) * | 2006-04-04 | 2007-10-25 | Ono Pharmaceut Co Ltd | プロスタグランジン類及びその類縁体の定量方法 |
-
2010
- 2010-01-21 EP EP10382011A patent/EP2348318A1/en not_active Withdrawn
-
2011
- 2011-01-21 CN CN201180010375.0A patent/CN102792166B/zh not_active Expired - Fee Related
- 2011-01-21 EP EP11700679.1A patent/EP2526425B1/en not_active Not-in-force
- 2011-01-21 CA CA2787582A patent/CA2787582A1/en not_active Abandoned
- 2011-01-21 ES ES11700679.1T patent/ES2485847T3/es active Active
- 2011-01-21 DK DK11700679.1T patent/DK2526425T3/da active
- 2011-01-21 PL PL11700679T patent/PL2526425T3/pl unknown
- 2011-01-21 WO PCT/EP2011/050867 patent/WO2011089240A1/en active Application Filing
- 2011-01-21 JP JP2012549374A patent/JP5732664B2/ja not_active Expired - Fee Related
- 2011-01-21 BR BR112012018289-7A patent/BR112012018289A2/pt not_active IP Right Cessation
- 2011-01-21 US US13/574,291 patent/US20130144114A1/en not_active Abandoned
-
2013
- 2013-05-08 HK HK13105497.2A patent/HK1177636A1/zh not_active IP Right Cessation
Non-Patent Citations (8)
Title |
---|
CYCLIC CHANGES IN THE CONCENTRATION OF PROSTAGLANDIN F2α IN HUMAN UTERINE FLUSHINGS;J. B.MAATHU;《Briiish Journal of Obstetrics and Gymecology》;19781231;第85卷;第207-210页 * |
Effect of dietary fat sources on systemic and intrauterine synthesis of prostaglandins during early pregnancy in gilts;R.Chartrand;《Journal of Animal Science》;20030331;第81卷(第3期);第726-734页 * |
Effectoftheconceptusonuterineprostaglandin-F2α andprostaglandin-E2releaseandsynthesisduring theperiimplantationperiodinthepig;Marta Wasielak;《Reproduction,Fertility and Development》;20091231;第21卷;第709-717页 * |
Hanna Achache.Endometrial receptivity markers,the journey to successful embryo implantation.《Human Reproduction Update》.2006,第12卷(第6期), * |
Human embryo implantation: current knowledge and clinical implications in assisted reproductive technology;Diederik Hoozemans;《Reproductive BioMedicine Online》;20041015;第9卷(第6期);第694页左栏第3段,右栏第2-4段,第698页右栏第1-2段,图6 * |
Kristina Gemzell-Danielesson.The effect of antiproestin(RU486)and prostaglandin biosynthesis inhibitor(naproxen) on uterine fluid prostaglandin F2α concentrations.《Human Reproduction 》.1994,第9卷(第9期), * |
前列腺素在胚胎着床和蜕膜化中的作用;邓文波;《细胞生物学杂志》;20081231;第30卷;第342-346页 * |
米非司酮和抗雌激素对卵巢切除后怀孕大鼠子宫的PGF2α和PGE2浓度的影响;郑尧;《国外医学妇产科学分册》;19981231;第25卷(第1期);第43-第44页 * |
Also Published As
Publication number | Publication date |
---|---|
BR112012018289A2 (pt) | 2021-04-20 |
JP2013518244A (ja) | 2013-05-20 |
HK1177636A1 (zh) | 2013-08-23 |
CN102792166A (zh) | 2012-11-21 |
US20130144114A1 (en) | 2013-06-06 |
PL2526425T3 (pl) | 2014-11-28 |
WO2011089240A1 (en) | 2011-07-28 |
JP5732664B2 (ja) | 2015-06-10 |
EP2526425B1 (en) | 2014-04-30 |
EP2348318A1 (en) | 2011-07-27 |
EP2526425A1 (en) | 2012-11-28 |
DK2526425T3 (da) | 2014-08-04 |
CA2787582A1 (en) | 2011-07-28 |
ES2485847T3 (es) | 2014-08-14 |
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Effective date of registration: 20150529 Address after: Valencia, Spain Applicant after: Equipo IVI Investigacion S. L. Address before: Valencia Applicant before: Equipo IVI Investigacion S. L. |
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