JP2013509376A5 - - Google Patents

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Publication number
JP2013509376A5
JP2013509376A5 JP2012535821A JP2012535821A JP2013509376A5 JP 2013509376 A5 JP2013509376 A5 JP 2013509376A5 JP 2012535821 A JP2012535821 A JP 2012535821A JP 2012535821 A JP2012535821 A JP 2012535821A JP 2013509376 A5 JP2013509376 A5 JP 2013509376A5
Authority
JP
Japan
Prior art keywords
phenyl
substituted
amino
propanamide
unsubstituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2012535821A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013509376A (ja
Filing date
Publication date
Priority claimed from EP09174390A external-priority patent/EP2316820A1/en
Application filed filed Critical
Publication of JP2013509376A publication Critical patent/JP2013509376A/ja
Publication of JP2013509376A5 publication Critical patent/JP2013509376A5/ja
Pending legal-status Critical Current

Links

JP2012535821A 2009-10-28 2010-10-28 ブラジキニン受容体アンタゴニストとして有用な２−アリール−プロピオンアミド誘導体およびそれらを含有する医薬組成物 Pending JP2013509376A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09174390.6 2009-10-28
EP09174390A EP2316820A1 (en) 2009-10-28 2009-10-28 2-aryl-propionamide derivatives useful as bradykinin receptor antagonists and pharmaceutical compositions containing them
PCT/EP2010/066324 WO2011051375A1 (en) 2009-10-28 2010-10-28 2-aryl-propionamide derivatives useful as bradykinin receptor antagonists and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
JP2013509376A JP2013509376A (ja) 2013-03-14
JP2013509376A5 true JP2013509376A5 (enExample) 2013-12-19

Family

ID=41559661

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012535821A Pending JP2013509376A (ja) 2009-10-28 2010-10-28 ブラジキニン受容体アンタゴニストとして有用な２−アリール−プロピオンアミド誘導体およびそれらを含有する医薬組成物

Country Status (8)

Country Link
US (1) US20120316169A1 (enExample)
EP (2) EP2316820A1 (enExample)
JP (1) JP2013509376A (enExample)
KR (1) KR20120084771A (enExample)
CN (1) CN102656140A (enExample)
AU (1) AU2010311466B2 (enExample)
WO (1) WO2011051375A1 (enExample)
ZA (1) ZA201203040B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102701949A (zh) * 2012-06-14 2012-10-03 山东新华制药股份有限公司 2-[4-(2-甲基-1-丙烯基)苯基]丙酸的制备方法
JP2016514141A (ja) * 2013-03-14 2016-05-19 シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド Ｂ２−ブラジキニン受容体媒介の血管浮腫の治療方法
WO2019046668A1 (en) * 2017-08-31 2019-03-07 Kezar Life Sciences AMIDE-SUBSTITUTED THIAZOLES AS INHIBITORS OF SECRETIC PROTEIN
US11427531B2 (en) * 2017-10-09 2022-08-30 Ramot At Tel-Aviv University Ltd. Modulators of potassium ion and TRPV1 channels and uses thereof
EP3884932A1 (en) * 2020-03-26 2021-09-29 Dompe' Farmaceutici S.P.A. Cxcl8 inhibitors for use in the treatment of covid-19
EP4008325A1 (en) * 2020-12-02 2022-06-08 Dompe' Farmaceutici S.P.A. Cxcl8 inhibitors for use in the treatment of covid-19
EP4125848A1 (en) * 2020-03-26 2023-02-08 Dompe' Farmaceutici SpA Cxcl8 inhibitors for use in the treatment of covid-19
CN115403483B (zh) * 2021-07-02 2024-01-26 河南省儿童医院郑州儿童医院 含二苯乙烯或二苯甲酮骨架的ca-4衍生物、药物组合物及其制备方法和应用
WO2023081841A1 (en) * 2021-11-05 2023-05-11 Georgiamune Llc Akt3 modulators
CN120093725B (zh) * 2025-03-13 2025-12-16 江西中医药大学附属医院 金发藓酮e在制备治疗糖尿病视网膜病变药物中的应用

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE764238A (fr) * 1971-03-17 1971-09-13 Lilly Industries Ltd Derives de phenylalkylamine
JPS6023105B2 (ja) * 1982-10-22 1985-06-05 八洲化学工業株式会社 α，α−ジメチルフエニル酢酸アニリド誘導体、その製造法及びそれを含有する除草剤
JPH06234763A (ja) * 1992-12-15 1994-08-23 Ishihara Sangyo Kaisha Ltd 環状アミド系化合物、それらの製造方法及びそれらを含有する除草性組成物
TW253885B (enExample) * 1992-12-15 1995-08-11 Ishihara Sangyo Kaisha
ATE185551T1 (de) * 1994-05-31 1999-10-15 Teijin Ltd Naphthalinderivate
FR2743562B1 (fr) 1996-01-11 1998-04-03 Sanofi Sa Derives de n-(arylsulfonyl) aminoacides, leur preparation, les compositions pharmaceutiques en contenant
GB9702194D0 (en) * 1997-02-04 1997-03-26 Lilly Co Eli Sulphonide derivatives
JP3752854B2 (ja) * 1998-07-15 2006-03-08 宇部興産株式会社 Ｎ−ベンジルカルバメイト化合物、その製法及び農園芸用の殺菌剤
ID30516A (id) * 1998-12-24 2001-12-13 Aventis Pharm Prod Inc Senyawa-senyawa (aminoiminometil atau aminometil) benzoheteroaril tersubstitusi
GB9913079D0 (en) 1999-06-04 1999-08-04 Novartis Ag Organic compounds
DE60005355T2 (de) 1999-07-15 2004-07-01 Pharmacopeia, Inc. Bradikinin b1 rezeptor antagonisten
ITMI20010395A1 (it) * 2001-02-27 2002-08-27 Dompe Spa Omega-amminoalchilammidi di acidi r-2-aril-propionici come inibitori della chemiotassi di cellule polimorfonucleate e mononucleate
WO2002092556A1 (en) 2001-05-14 2002-11-21 Novartis Ag Sulfonamide derivatives
AU2002346048A1 (en) 2001-06-07 2002-12-16 Merck And Co., Inc. Benzodiazepine bradykinin antagonists
DE10134721A1 (de) 2001-07-17 2003-02-06 Bayer Ag Tetrahydrochinoxaline
AR036375A1 (es) * 2001-08-30 2004-09-01 Novartis Ag Compuestos pirrolo [2,3-d] pirimidina -2- carbonitrilo, un proceso para su preparacion, una composicion farmaceutica y el uso de dichos compuestos para la preparacion de medicamentos
US7183281B2 (en) 2002-05-03 2007-02-27 Elan Pharmaceuticals, Inc. Sulfonylquinoxalone derivatives and related compounds as bradykinin antagonists
FR2840897B1 (fr) 2002-06-14 2004-09-10 Fournier Lab Sa Nouveaux derives d'arylsulfonamides et leur utilisation en therapeutique
US20040063761A1 (en) 2002-08-06 2004-04-01 Kuduk Scott D. 2-(biarylalkyl)amino-3-(fluoroalkanoylamino)pyridine derivatives
US20040029920A1 (en) 2002-08-06 2004-02-12 Kuduk Scott D. 2-(biarylalkyl)amino-3-(heterocyclylcarbonylamino)-pyridine derivatives
US20040034064A1 (en) 2002-08-06 2004-02-19 Kuduk Scott D. 2-(biarylalkyl)amino-3-(alkanoylamino)pyridine derivatives
US6908921B2 (en) 2002-12-13 2005-06-21 Merck & Co., Inc. Quinoxalinone derivatives as bradykinin B1 antagonists
WO2004056744A1 (en) * 2002-12-23 2004-07-08 Janssen Pharmaceutica N.V. Adamantyl acetamides as hydroxysteroid dehydrogenase inhibitors
KR100707123B1 (ko) * 2003-07-02 2007-04-16 그뤼넨탈 게엠베하 바닐로이드 수용체의 길항제로서 강력한 진통효과를나타내는 4-(메틸설포닐아미노)페닐 동족체 및 이를함유하는 약학적 조성물
EP1663960B1 (en) * 2003-09-25 2011-08-24 Dompe' S.P.A. Amidines and derivatives thereof and pharmaceutical compositions containing them
CA2545711A1 (en) * 2003-11-13 2005-06-02 Ambit Biosciences Corporation Urea derivatives as kinase modulators
JP2005170939A (ja) * 2003-11-20 2005-06-30 Takeda Chem Ind Ltd 糖尿病の予防・治療剤
DE602005016937D1 (de) * 2004-03-23 2009-11-12 Dompe Pha R Ma Spa Res & Mfg Pharmazeutische zusammensetzung
CN1984933A (zh) 2004-07-09 2007-06-20 三井化学株式会社 热塑性树脂
ES2377758T3 (es) * 2004-11-12 2012-03-30 Bristol-Myers Squibb Company Compuestos tricíclicos basados en tiazolo[4,5-b]piridina imidazo-fusionada y composiciones farmacéuticas que los comprenden
US20060111392A1 (en) * 2004-11-23 2006-05-25 Wood Michael R Substituted biaryl-carboxylate derivatives
ME01868B (me) * 2004-12-15 2010-10-31 Dompe Pha R Ma Spa Res & Mfg Derivati 2-arilpropionske kiseline i farmaceutske smeše, koje ih sadrže
TW200715993A (en) * 2005-06-15 2007-05-01 Senomyx Inc Bis-aromatic amides and their uses as sweet flavor modifiers, tastants, and taste enhancers
PT2094638E (pt) * 2006-12-19 2012-11-20 Dompe Spa Ácidos 2-aril-fluoropropanóicos e derivados e composições farmacêuticas que os contêm
WO2009001127A1 (en) * 2007-06-26 2008-12-31 Astrazeneca Ab Cyanocyclopropylcarboxamides as cathepsin inhibitors
WO2009075874A1 (en) * 2007-12-13 2009-06-18 Amgen Inc. Gamma secretase modulators
CN106243037A (zh) * 2009-05-07 2016-12-21 格吕伦塔尔有限公司 作为香草类化合物受体之配体的取代的苯基脲及苯基酰胺

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