|
EP2455382B1
(en)
|
2005-12-13 |
2016-10-26 |
Incyte Holdings Corporation |
Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors
|
|
EP3070090B1
(en)
|
2007-06-13 |
2018-12-12 |
Incyte Holdings Corporation |
Use of salts of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h- pyrazol-1-yl)-3- cyclopentylpropanenitrile
|
|
CN102271515B
(zh)
|
2008-10-31 |
2014-07-02 |
健泰科生物技术公司 |
吡唑并嘧啶jak抑制剂化合物和方法
|
|
SG176111A1
(en)
|
2009-05-22 |
2011-12-29 |
Incyte Corp |
3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]octane- or heptane-nitrile as jak inhibitors
|
|
CN104945420A
(zh)
|
2009-06-29 |
2015-09-30 |
因塞特公司 |
作为pi3k抑制剂的嘧啶酮类
|
|
UA110324C2
(en)
|
2009-07-02 |
2015-12-25 |
Genentech Inc |
Jak inhibitory compounds based on pyrazolo pyrimidine
|
|
WO2011075643A1
(en)
|
2009-12-18 |
2011-06-23 |
Incyte Corporation |
Substituted heteroaryl fused derivatives as pi3k inhibitors
|
|
PT3354652T
(pt)
|
2010-03-10 |
2020-07-20 |
Incyte Holdings Corp |
Derivados de piperidin-4-ilazetidina como inibidores de jak1
|
|
AR081823A1
(es)
|
2010-04-14 |
2012-10-24 |
Incyte Corp |
DERIVADOS FUSIONADOS COMO INHIBIDORES DE PI3Kd
|
|
RS54824B1
(sr)
|
2010-05-21 |
2016-10-31 |
Incyte Holdings Corp |
Topikalna formulacija za inhibiciju jak-a
|
|
US9062055B2
(en)
|
2010-06-21 |
2015-06-23 |
Incyte Corporation |
Fused pyrrole derivatives as PI3K inhibitors
|
|
US9040545B2
(en)
|
2010-08-20 |
2015-05-26 |
Cellzome Limited |
Heterocyclyl pyrazolopyrimidine analogues as selective JAK inhibitors
|
|
MX2013003019A
(es)
|
2010-09-15 |
2013-05-28 |
Hoffmann La Roche |
Compuestos de azabenzotiazol, composiciones y metodos de uso.
|
|
CA2818542A1
(en)
|
2010-11-19 |
2012-05-24 |
Incyte Corporation |
Cyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as jak inhibitors
|
|
MX2013005445A
(es)
*
|
2010-11-19 |
2013-07-29 |
Hoffmann La Roche |
Pirazolopiridinas y el uso de pirazolopiridinas como inhibidores de tirosina cinasa 2 (tyk2).
|
|
EP2655374B1
(en)
|
2010-12-20 |
2019-10-23 |
Incyte Holdings Corporation |
N-(1-(substituted-phenyl)ethyl)-9h-purin-6-amines as pi3k inhibitors
|
|
US9108984B2
(en)
|
2011-03-14 |
2015-08-18 |
Incyte Corporation |
Substituted diamino-pyrimidine and diamino-pyridine derivatives as PI3K inhibitors
|
|
WO2012135009A1
(en)
|
2011-03-25 |
2012-10-04 |
Incyte Corporation |
Pyrimidine-4,6-diamine derivatives as pi3k inhibitors
|
|
WO2012143320A1
(en)
|
2011-04-18 |
2012-10-26 |
Cellzome Limited |
(7h-pyrrolo[2,3-d]pyrimidin-2-yl)amine compounds as jak3 inhibitors
|
|
MY165963A
(en)
|
2011-06-20 |
2018-05-18 |
Incyte Holdings Corp |
Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as jak inhibitors
|
|
CN103781780B
(zh)
*
|
2011-07-28 |
2015-11-25 |
赛尔佐姆有限公司 |
作为jak抑制剂的杂环基嘧啶类似物
|
|
WO2013017480A1
(en)
|
2011-07-29 |
2013-02-07 |
Cellzome Limited |
Pyrazolo[4,3-c]pyridine derivatives as jak inhibitors
|
|
WO2013017479A1
(en)
|
2011-07-29 |
2013-02-07 |
Cellzome Limited |
Pyrazolo[4,3-c]pyridine derivatives as jak inhibitors
|
|
KR102507287B1
(ko)
|
2011-09-02 |
2023-03-07 |
인사이트 홀딩스 코포레이션 |
Ｐｉ３ｋ 억제제로서 헤테로시클릴아민
|
|
UA111854C2
(uk)
|
2011-09-07 |
2016-06-24 |
Інсайт Холдінгс Корпорейшн |
Способи і проміжні сполуки для отримання інгібіторів jak
|
|
WO2013041605A1
(en)
|
2011-09-20 |
2013-03-28 |
Cellzome Limited |
Pyrazolo[4,3-c]pyridine derivatives as kinase inhibitors
|
|
CN104169272A
(zh)
|
2011-12-23 |
2014-11-26 |
赛尔佐姆有限公司 |
作为激酶抑制剂的嘧啶-2,4-二胺衍生物
|
|
CN103193600B
(zh)
*
|
2012-01-07 |
2016-04-06 |
浙江九洲药物科技有限公司 |
卡巴拉汀中间体的制备方法
|
|
EP2807161B1
(en)
*
|
2012-01-28 |
2017-10-04 |
Merck Patent GmbH |
Triazolo[4,5-d]pyrimidine derivatives
|
|
AR090548A1
(es)
|
2012-04-02 |
2014-11-19 |
Incyte Corp |
Azaheterociclobencilaminas biciclicas como inhibidores de pi3k
|
|
EP2855451B1
(en)
|
2012-05-24 |
2017-10-04 |
Cellzome Limited |
Heterocyclyl pyrimidine analogues as tyk2 inhibitors
|
|
CN113384546A
(zh)
|
2012-11-15 |
2021-09-14 |
因赛特公司 |
鲁索利替尼的缓释剂型
|
|
MA38287B1
(fr)
|
2013-01-23 |
2018-08-31 |
Astrazeneca Ab |
Nouveaux dérivés aminopyrazine pour le traitement ou la prévention du cancer
|
|
WO2014138168A1
(en)
|
2013-03-06 |
2014-09-12 |
Incyte Corporation |
Processes and intermediates for making a jak inhibitor
|
|
SG10201801069QA
(en)
|
2013-08-07 |
2018-03-28 |
Incyte Corp |
Sustained release dosage forms for a jak1 inhibitor
|
|
WO2015038417A1
(en)
*
|
2013-09-10 |
2015-03-19 |
Asana Biosciences, Llc |
Compounds for regulating fak and/or src pathways
|
|
CA2925953C
(en)
|
2013-10-17 |
2021-11-02 |
Dow Agrosciences Llc |
Processes for the preparation of pesticidal compounds
|
|
PE20211782A1
(es)
|
2014-05-23 |
2021-09-08 |
Hoffmann La Roche |
Compuestos de 5-cloro-2-difluorometoxifenil pirazolopirimidina, composiciones y metodos de uso de los mismos
|
|
US9498467B2
(en)
|
2014-05-30 |
2016-11-22 |
Incyte Corporation |
Treatment of chronic neutrophilic leukemia (CNL) and atypical chronic myeloid leukemia (aCML) by inhibitors of JAK1
|
|
TW201613916A
(en)
|
2014-06-03 |
2016-04-16 |
Gilead Sciences Inc |
TANK-binding kinase inhibitor compounds
|
|
WO2015191677A1
(en)
|
2014-06-11 |
2015-12-17 |
Incyte Corporation |
Bicyclic heteroarylaminoalkyl phenyl derivatives as pi3k inhibitors
|
|
NZ729618A
(en)
|
2014-09-26 |
2018-07-27 |
Gilead Sciences Inc |
Aminotriazine derivatives useful as tank-binding kinase inhibitor compounds
|
|
SI3831833T1
(sl)
|
2015-02-27 |
2023-03-31 |
Incyte Holdings Corporation |
Postopki za pripravo inhibitorja PI3K
|
|
US10259816B2
(en)
*
|
2015-04-24 |
2019-04-16 |
Guangzhou Maxinovel Pharmaceuticals Co., Ltd. |
Condensed-ring pyrimidylamino derivative, preparation method therefor, and intermediate, pharmaceutical composition and applications thereof
|
|
US9732097B2
(en)
|
2015-05-11 |
2017-08-15 |
Incyte Corporation |
Process for the synthesis of a phosphoinositide 3-kinase inhibitor
|
|
US9988401B2
(en)
|
2015-05-11 |
2018-06-05 |
Incyte Corporation |
Crystalline forms of a PI3K inhibitor
|
|
EP3394044A1
(en)
|
2015-12-17 |
2018-10-31 |
Gilead Sciences, Inc. |
Tank-binding kinase inhibitor compounds
|
|
HUE059242T2
(hu)
*
|
2016-07-29 |
2022-11-28 |
Rapt Therapeutics Inc |
Azetidin-származékok mint kemokin receptor modulátorok és felhasználásuk
|
|
JP2020503336A
(ja)
|
2016-12-29 |
2020-01-30 |
ダウ アグロサイエンシィズ エルエルシー |
殺有害生物化合物の調製方法
|
|
CN110325036B
(zh)
*
|
2016-12-29 |
2021-10-26 |
美国陶氏益农公司 |
用于制备杀虫化合物的方法
|
|
PL233595B1
(pl)
*
|
2017-05-12 |
2019-11-29 |
Celon Pharma Spolka Akcyjna |
Pochodne pirazolo[1,5-a]pirymidyny jako inhibitory kinazy JAK
|
|
WO2018215389A1
(en)
|
2017-05-22 |
2018-11-29 |
F. Hoffmann-La Roche Ag |
Therapeutic compounds and compositions, and methods of use thereof
|
|
SG11202005264PA
(en)
|
2017-12-05 |
2020-07-29 |
Oscotec Inc |
Pyrrolo(pyrazolo)pyrimidine derivative as lrrk2 inhibitor
|
|
AR113922A1
(es)
|
2017-12-08 |
2020-07-01 |
Incyte Corp |
Terapia de combinación de dosis baja para el tratamiento de neoplasias mieloproliferativas
|
|
EA202091830A1
(ru)
|
2018-01-30 |
2020-12-29 |
Инсайт Корпорейшн |
Способы и промежуточные соединения для получения ингибитора jak
|
|
WO2019166560A1
(en)
|
2018-02-28 |
2019-09-06 |
Basf Se |
Use of n-functionalized alkoxy pyrazole compounds as nitrification inhibitors
|
|
EP3758491A1
(en)
|
2018-02-28 |
2021-01-06 |
Basf Se |
Use of pyrazole propargyl ethers as nitrification inhibitors
|
|
MD3773593T2
(ro)
|
2018-03-30 |
2024-10-31 |
Incyte Corp |
Tratament hidradenitei supurative utilizând inhibitori ai JAK
|
|
CA3101323A1
(en)
|
2018-06-01 |
2019-12-05 |
Incyte Corporation |
Dosing regimen for the treatment of pi3k related disorders
|
|
CN110885331B
(zh)
*
|
2018-09-11 |
2021-07-09 |
中国药科大学 |
一种6-氨基-1H-吡唑并[3，4-d]嘧啶类JAK激酶抑制剂的制备与应用
|
|
MA53188A1
(fr)
*
|
2018-10-11 |
2021-12-31 |
Basf As |
Composés aromatiques et leurs utilisations pharmaceutiques
|
|
WO2020092015A1
(en)
|
2018-11-02 |
2020-05-07 |
University Of Rochester |
Therapeutic mitigation of epithelial infection
|
|
JP7617030B2
(ja)
*
|
2019-05-08 |
2025-01-17 |
ビマラン バイオサイエンシーズ，インク． |
Ｊａｋ阻害剤
|
|
TWI899080B
(zh)
*
|
2019-05-27 |
2025-10-01 |
大陸商迪哲（江蘇）醫藥股份有限公司 |
Ｄｎａ依賴性蛋白激酶抑制劑
|
|
KR20220051351A
(ko)
*
|
2019-08-08 |
2022-04-26 |
비말란 바이오사이언스즈, 인크. |
Jak 억제제
|
|
ES3025474T3
(en)
*
|
2020-01-15 |
2025-06-09 |
Ksq Therapeutics Inc |
Compositions of substituted pyrazolopyrimidines and uses thereof
|
|
US11833155B2
(en)
|
2020-06-03 |
2023-12-05 |
Incyte Corporation |
Combination therapy for treatment of myeloproliferative neoplasms
|
|
KR20230098186A
(ko)
*
|
2020-10-30 |
2023-07-03 |
케이에스큐 세러퓨틱스 인코포레이티드 |
치환된 피라졸로피리미딘의 고체 상태 형태 및 이의 용도
|
|
AR125955A1
(es)
|
2021-05-21 |
2023-08-30 |
Basf Se |
Uso de un compuesto de alcoxi pirazol n-funcionalizado como inhibidor de nitrificación
|
|
WO2024238570A1
(en)
*
|
2023-05-15 |
2024-11-21 |
Aleksia Therapeutics, Inc. |
Cdk2 inhibitor pyrazolopyrimidine compounds
|