JP2022511515A5 - - Google Patents
Info
- Publication number
- JP2022511515A5 JP2022511515A5 JP2021531985A JP2021531985A JP2022511515A5 JP 2022511515 A5 JP2022511515 A5 JP 2022511515A5 JP 2021531985 A JP2021531985 A JP 2021531985A JP 2021531985 A JP2021531985 A JP 2021531985A JP 2022511515 A5 JP2022511515 A5 JP 2022511515A5
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- JP
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024102890A JP2024150464A (ja) | 2018-12-20 | 2024-06-26 | 置換されたピラゾロピリミジン及び置換されたプリンならびにユビキチン特異的プロセシングプロテアーゼ１（ｕｓｐ１）阻害剤としてのそれらの使用 |
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862783014P | 2018-12-20 | 2018-12-20 | |
| US62/783,014 | 2018-12-20 | ||
| US201962799423P | 2019-01-31 | 2019-01-31 | |
| US62/799,423 | 2019-01-31 | ||
| US201962857986P | 2019-06-06 | 2019-06-06 | |
| US62/857,986 | 2019-06-06 | ||
| US201962868616P | 2019-06-28 | 2019-06-28 | |
| US62/868,616 | 2019-06-28 | ||
| US201962946263P | 2019-12-10 | 2019-12-10 | |
| US62/946,263 | 2019-12-10 | ||
| PCT/US2019/067521 WO2020132269A1 (en) | 2018-12-20 | 2019-12-19 | Substituted pyrazolopyrimidines and substituted purines and their use as ubiquitin-specific-processing protease 1 (usp1) inhibitors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024102890A Division JP2024150464A (ja) | 2018-12-20 | 2024-06-26 | 置換されたピラゾロピリミジン及び置換されたプリンならびにユビキチン特異的プロセシングプロテアーゼ１（ｕｓｐ１）阻害剤としてのそれらの使用 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022511515A JP2022511515A (ja) | 2022-01-31 |
| JP2022511515A5 true JP2022511515A5 (https=) | 2022-12-26 |
| JPWO2020132269A5 JPWO2020132269A5 (https=) | 2022-12-26 |
| JP7662519B2 JP7662519B2 (ja) | 2025-04-15 |
Family
ID=71100912
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021531985A Active JP7662519B2 (ja) | 2018-12-20 | 2019-12-19 | 置換されたピラゾロピリミジン及び置換されたプリンならびにユビキチン特異的プロセシングプロテアーゼ１（ｕｓｐ１）阻害剤としてのそれらの使用 |
| JP2024102890A Pending JP2024150464A (ja) | 2018-12-20 | 2024-06-26 | 置換されたピラゾロピリミジン及び置換されたプリンならびにユビキチン特異的プロセシングプロテアーゼ１（ｕｓｐ１）阻害剤としてのそれらの使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024102890A Pending JP2024150464A (ja) | 2018-12-20 | 2024-06-26 | 置換されたピラゾロピリミジン及び置換されたプリンならびにユビキチン特異的プロセシングプロテアーゼ１（ｕｓｐ１）阻害剤としてのそれらの使用 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US11485736B2 (https=) |
| EP (1) | EP3897652A4 (https=) |
| JP (2) | JP7662519B2 (https=) |
| KR (1) | KR102912147B1 (https=) |
| CN (1) | CN113164485A (https=) |
| AU (1) | AU2019405925B2 (https=) |
| BR (1) | BR112021010715A2 (https=) |
| CA (1) | CA3122108A1 (https=) |
| CL (1) | CL2021001575A1 (https=) |
| CO (1) | CO2021009078A2 (https=) |
| IL (1) | IL284050B2 (https=) |
| MX (1) | MX2021007179A (https=) |
| PH (1) | PH12021551402A1 (https=) |
| SG (1) | SG11202106232TA (https=) |
| TW (2) | TWI895986B (https=) |
| WO (1) | WO2020132269A1 (https=) |
Families Citing this family (60)
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| CN114031556B (zh) * | 2021-11-08 | 2023-03-31 | 温州大学 | 一种绿色的一锅法制备5-氨基-n-芳基-3-芳基吡唑类化合物的合成方法 |
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| CR20240191A (es) * | 2021-11-12 | 2024-09-13 | Insilico Medicine Ip Ltd | Inhibidores de molécula pequeña de proteasa 1 específica de ubiquitina (usp1) y usos de los mismos |
| EP4430041A4 (en) * | 2021-11-12 | 2025-09-24 | Insilico Medicine Ip Ltd | SMALL MOLECULE INHIBITORS OF UBIQUITIN-SPECIFIC PROTEASE 1 (USP1) AND THEIR USES |
| CN114181237B (zh) * | 2021-12-01 | 2024-02-23 | 上海凌凯医药科技有限公司 | 一种1-异丙基吡唑-5-硼酸频那醇酯的合成方法 |
| IL312982A (en) * | 2021-12-09 | 2024-07-01 | Ksq Therapeutics Inc | Methods for the preparation of converted pyrazolopyrimidines |
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| CN116925098B (zh) * | 2022-04-09 | 2026-02-17 | 深圳湾实验室 | 靶向泛素特异性蛋白酶1(usp1)的小分子抑制剂及其应用 |
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| WO2024078436A1 (zh) * | 2022-10-09 | 2024-04-18 | 海南先声再明医药股份有限公司 | 杂环并嘧啶类化合物、药物组合物及其应用 |
| WO2024086790A1 (en) | 2022-10-21 | 2024-04-25 | Exelixis, Inc. | 4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[4,3-c]PYRIDINE COMPOUNDS AND DERIVATIVES AS USP1 INHIBITORS |
| WO2024094170A1 (zh) * | 2022-11-04 | 2024-05-10 | 深圳晶泰科技有限公司 | 泛素特异性蛋白酶1的抑制剂及其应用 |
| CN120513237A (zh) | 2023-01-12 | 2025-08-19 | 先正达农作物保护股份公司 | 除草咪唑化合物 |
| CN120603835A (zh) * | 2023-01-20 | 2025-09-05 | 杭州英创医药科技有限公司 | 作为usp1抑制剂的化合物 |
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| WO2025095751A1 (ko) * | 2023-10-30 | 2025-05-08 | 현대약품 주식회사 | 신규한 화합물, 및 이를 포함하는 암의 예방 또는 치료용 약학적 조성물 |
| TW202535865A (zh) | 2023-10-31 | 2025-09-16 | 美商必治妥美雅史谷比公司 | 泛素特異性加工蛋白酶1 (usp1) 化合物 |
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| WO2025102016A1 (en) | 2023-11-10 | 2025-05-15 | Vrise Therapeutics, Inc. | Novel molecules as inhibitors of dna damage repair pathway |
| WO2025151705A1 (en) | 2024-01-10 | 2025-07-17 | Vrise Therapeutics, Inc. | Novel inhibitors of dna damage repair pathway |
| WO2025180502A1 (zh) * | 2024-03-01 | 2025-09-04 | 上海齐鲁制药研究中心有限公司 | 一种联合用药物组合物及其用途 |
| KR20250138136A (ko) * | 2024-03-12 | 2025-09-19 | 현대약품 주식회사 | 신규한 화합물, 및 이를 포함하는 암의 예방 또는 치료용 약학적 조성물 |
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2019
- 2019-12-19 BR BR112021010715A patent/BR112021010715A2/pt unknown
- 2019-12-19 TW TW113105437A patent/TWI895986B/zh active
- 2019-12-19 PH PH1/2021/551402A patent/PH12021551402A1/en unknown
- 2019-12-19 JP JP2021531985A patent/JP7662519B2/ja active Active
- 2019-12-19 SG SG11202106232TA patent/SG11202106232TA/en unknown
- 2019-12-19 AU AU2019405925A patent/AU2019405925B2/en active Active
- 2019-12-19 CN CN201980079551.2A patent/CN113164485A/zh active Pending
- 2019-12-19 IL IL284050A patent/IL284050B2/en unknown
- 2019-12-19 US US16/721,079 patent/US11485736B2/en active Active
- 2019-12-19 MX MX2021007179A patent/MX2021007179A/es unknown
- 2019-12-19 EP EP19897934.6A patent/EP3897652A4/en active Pending
- 2019-12-19 KR KR1020217017482A patent/KR102912147B1/ko active Active
- 2019-12-19 WO PCT/US2019/067521 patent/WO2020132269A1/en not_active Ceased
- 2019-12-19 TW TW108146728A patent/TWI834784B/zh active
- 2019-12-19 CA CA3122108A patent/CA3122108A1/en active Pending
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2021
- 2021-06-16 CL CL2021001575A patent/CL2021001575A1/es unknown
- 2021-07-12 CO CONC2021/0009078A patent/CO2021009078A2/es unknown
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2022
- 2022-10-11 US US18/045,770 patent/US11787813B2/en active Active
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2024
- 2024-06-26 JP JP2024102890A patent/JP2024150464A/ja active Pending