JP2013504582A5 - - Google Patents

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Publication number
JP2013504582A5
JP2013504582A5 JP2012528891A JP2012528891A JP2013504582A5 JP 2013504582 A5 JP2013504582 A5 JP 2013504582A5 JP 2012528891 A JP2012528891 A JP 2012528891A JP 2012528891 A JP2012528891 A JP 2012528891A JP 2013504582 A5 JP2013504582 A5 JP 2013504582A5
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JP
Japan
Prior art keywords
cancer
pharmaceutical composition
leukemia
lymphoma
composition according
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JP2012528891A
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English (en)
Japanese (ja)
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JP5851403B2 (ja
JP2013504582A (ja
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Priority claimed from PCT/US2010/048247 external-priority patent/WO2011031842A1/en
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Publication of JP2013504582A5 publication Critical patent/JP2013504582A5/ja
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JP2012528891A 2009-09-11 2010-09-09 有糸分裂阻害剤耐性癌の治療における使用のためのn−4(−((3−(2−アミノ−4ピリミジニル)−2−ピリジニル)オキシ)フェニル)−4−(4−メチル−2−チエニル)−1−フタラジンアミン Active JP5851403B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24152709P 2009-09-11 2009-09-11
US61/241,527 2009-09-11
PCT/US2010/048247 WO2011031842A1 (en) 2009-09-11 2010-09-09 N-4 ( - ( ( 3- ( 2 -amino-4 pyrimidinyl) -2 -pyridinyl) oxy) phenyl) -4- (4-methyl-2-thienyl) -1-phthalazinamine for use in the treatment of antimitotic agent resistant cancer

Publications (3)

Publication Number Publication Date
JP2013504582A JP2013504582A (ja) 2013-02-07
JP2013504582A5 true JP2013504582A5 (enExample) 2013-08-15
JP5851403B2 JP5851403B2 (ja) 2016-02-03

Family

ID=43216900

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012528891A Active JP5851403B2 (ja) 2009-09-11 2010-09-09 有糸分裂阻害剤耐性癌の治療における使用のためのn−4(−((3−(2−アミノ−4ピリミジニル)−2−ピリジニル)オキシ)フェニル)−4−(4−メチル−2−チエニル)−1−フタラジンアミン

Country Status (34)

Country Link
US (1) US20120028917A1 (enExample)
EP (2) EP2475368B1 (enExample)
JP (1) JP5851403B2 (enExample)
KR (1) KR20120082896A (enExample)
CN (1) CN102869361A (enExample)
AU (1) AU2010292225C1 (enExample)
BR (1) BR112012008325A2 (enExample)
CA (1) CA2773838C (enExample)
CL (1) CL2012000640A1 (enExample)
CR (1) CR20120171A (enExample)
DK (1) DK2475368T3 (enExample)
EA (1) EA020526B1 (enExample)
ES (1) ES2528485T3 (enExample)
HK (1) HK1205457A1 (enExample)
HR (1) HRP20150104T1 (enExample)
HU (1) HUE024568T2 (enExample)
IL (1) IL218569A0 (enExample)
MA (1) MA33658B1 (enExample)
ME (1) ME02048B (enExample)
MX (1) MX2012003041A (enExample)
NZ (1) NZ598758A (enExample)
PE (1) PE20120895A1 (enExample)
PH (1) PH12012500504A1 (enExample)
PL (1) PL2475368T3 (enExample)
PT (1) PT2475368E (enExample)
RS (1) RS53807B1 (enExample)
SG (1) SG179102A1 (enExample)
SI (1) SI2475368T1 (enExample)
SM (1) SMT201500028B (enExample)
TN (1) TN2012000110A1 (enExample)
TW (1) TW201121956A (enExample)
UA (1) UA107675C2 (enExample)
WO (1) WO2011031842A1 (enExample)
ZA (1) ZA201202472B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013181462A1 (en) * 2012-05-31 2013-12-05 Amgen Inc. Use of amg 900 for the treatment of cancer
CN103664737A (zh) * 2012-09-25 2014-03-26 杨子娇 一类治疗房角狭窄的化合物及其用途
WO2015046783A1 (en) 2013-09-30 2015-04-02 Korea Institute Of Radiological & Medical Sciences Pharmaceutical composition for treatment of radiation- or drug-resistant cancer comprising hrp-3 inhibitor
MX393610B (es) 2013-11-11 2025-03-24 Amgen Inc Terapia de combinacion que incluye un inhibidor mdm2 y uno o mas agentes farmaceuticamente activos adicionales para el tratamiento de canceres
ES2784325T3 (es) * 2013-12-03 2020-09-24 Amgen Inc Formas cristalinas de sales farmacéuticamente aceptables de N-(4-((3-(2-amino-4-pirimidinil)-2-piridinil)oxi)fenil)-4-(4-metil-2-tienil)-1-ftalazinamina y usos de las mismas
JP6506313B2 (ja) * 2014-02-21 2019-04-24 フロスト バイオロジック,インコーポレーテッド 癌及び増殖性疾患の治療のための抗有糸分裂性アミド
BR112018071023A2 (pt) * 2016-04-15 2019-02-05 Felicitex Therapeutics Inc combinações para o tratamento de neoplasmas utilizando o direcionamento de células inativas e inibidores da mitose
JOP20190272A1 (ar) 2017-05-22 2019-11-21 Amgen Inc مثبطات kras g12c وطرق لاستخدامها
EP3679040B1 (en) 2017-09-08 2022-08-03 Amgen Inc. Inhibitors of kras g12c and methods of using the same
JP7266043B2 (ja) 2018-05-04 2023-04-27 アムジエン・インコーポレーテツド KRas G12C阻害剤及びそれを使用する方法
MA51848A (fr) 2018-06-12 2021-04-21 Amgen Inc Inhibiteurs de kras g12c et leurs procédés d'utilisation
JP7377679B2 (ja) 2018-11-19 2023-11-10 アムジエン・インコーポレーテツド がん治療のためのkrasg12c阻害剤及び1種以上の薬学的に活性な追加の薬剤を含む併用療法
JP7092935B2 (ja) 2019-05-21 2022-06-28 アムジエン・インコーポレーテツド 固体形態

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2531142A1 (en) * 2003-07-03 2005-01-13 Cambridge University Technical Services Ltd Use of aurora kinase inhibitors for reducing the resistance of cancer cells
US7560551B2 (en) * 2006-01-23 2009-07-14 Amgen Inc. Aurora kinase modulators and method of use
HUE028504T2 (en) 2006-01-23 2016-12-28 Amgen Inc Aurora kinase modulators and method for their application
UA93538C2 (en) * 2006-01-23 2011-02-25 Амген Инк. Aurora kinase modulators and method of use
GB0609621D0 (en) * 2006-05-16 2006-06-21 Astrazeneca Ab Novel co-crystal
GB0609619D0 (en) * 2006-05-16 2006-06-21 Astrazeneca Ab Combination

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