JP2012532868A5 - - Google Patents
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- Publication number
- JP2012532868A5 JP2012532868A5 JP2012519544A JP2012519544A JP2012532868A5 JP 2012532868 A5 JP2012532868 A5 JP 2012532868A5 JP 2012519544 A JP2012519544 A JP 2012519544A JP 2012519544 A JP2012519544 A JP 2012519544A JP 2012532868 A5 JP2012532868 A5 JP 2012532868A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- substituted
- aryl
- compound
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22394609P | 2009-07-08 | 2009-07-08 | |
| US61/223,946 | 2009-07-08 | ||
| PCT/US2010/001926 WO2011005322A2 (en) | 2009-07-08 | 2010-07-08 | N-alkoxyamide conjugates as imaging agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012532868A JP2012532868A (ja) | 2012-12-20 |
| JP2012532868A5 true JP2012532868A5 (https=) | 2013-08-29 |
| JP5676600B2 JP5676600B2 (ja) | 2015-02-25 |
Family
ID=43429724
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012519544A Expired - Fee Related JP5676600B2 (ja) | 2009-07-08 | 2010-07-08 | 造影剤としてのｎ−アルコキシアミド抱合体 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US8877157B2 (https=) |
| EP (1) | EP2451776B1 (https=) |
| JP (1) | JP5676600B2 (https=) |
| CN (1) | CN102781909B (https=) |
| AU (1) | AU2010271097B2 (https=) |
| CA (1) | CA2803520C (https=) |
| WO (1) | WO2011005322A2 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI618544B (zh) | 2006-12-26 | 2018-03-21 | 藍瑟斯醫學影像公司 | 使心臟神經分布顯像之配位體 |
| US8361438B2 (en) | 2008-01-08 | 2013-01-29 | Lantheus Medical Imaging, Inc. | N-alkoxyamide conjugates as imaging agents |
| CA2803520C (en) | 2009-07-08 | 2019-10-22 | Lantheus Medical Imaging, Inc. | N-alkoxyamide conjugates as imaging agents |
| AU2011253052B2 (en) | 2010-05-11 | 2015-05-14 | Lantheus Medical Imaging, Inc. | Compositions, methods and systems for the synthesis and use of imaging agents |
| GB201102189D0 (en) | 2011-02-08 | 2011-03-23 | King S College London | Materials and methods relating to cardiovascular imaging |
| EP2753605B1 (en) * | 2011-09-09 | 2019-03-27 | Lantheus Medical Imaging, Inc. | Compositions, methods, and systems for the synthesis and use of imaging agents |
| US20150023873A1 (en) | 2011-11-11 | 2015-01-22 | Lantheus Medical Imaging, Inc. | Evaluation of presence of and vulnerability to atrial fibrillation and other indications using matrix metalloproteinase-based imaging |
| AU2013203000B9 (en) | 2012-08-10 | 2017-02-02 | Lantheus Medical Imaging, Inc. | Compositions, methods, and systems for the synthesis and use of imaging agents |
| TWI780082B (zh) | 2016-11-18 | 2022-10-11 | 日商安斯泰來製藥股份有限公司 | 新穎抗人類ＭＵＣ１抗體Ｆａｂ片段 |
| TWI795415B (zh) | 2017-07-07 | 2023-03-11 | 日商安斯泰來製藥股份有限公司 | 新穎的抗人類ＣＥＡＣＡＭ５抗體Ｆａｂ片段 |
| MX2020012351A (es) | 2018-05-17 | 2021-01-29 | Astellas Pharma Inc | Complejo que tiene fragmento fab de anticuerpo anti-muc1 de humano, enlazador peptido y/o ligando. |
| CA3115747A1 (en) | 2018-10-10 | 2020-04-16 | Astellas Pharma Inc. | Pharmaceutical composition containing tagged site-antihuman antibody fab fragment complex |
| JPWO2020145228A1 (ja) * | 2019-01-07 | 2021-11-11 | アステラス製薬株式会社 | 配位子及びＣＥＡＣＡＭ５抗体Ｆａｂフラグメントからなる複合体 |
| CN117486698B (zh) * | 2023-10-30 | 2025-08-19 | 国网安徽省电力有限公司电力科学研究院 | 烯醇硅醚类化合物制备c-c键偶联产物的方法与sf6的应用 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5122885A (en) | 1974-08-13 | 1976-02-23 | Sagami Chem Res | Ashiru ll aminosan oo chikanhidorokisamidono seizohoho |
| JPS5910322B2 (ja) | 1975-07-30 | 1984-03-08 | 三井東圧化学株式会社 | 殺草剤 |
| US4859777A (en) | 1981-07-01 | 1989-08-22 | Eastman Kodak Company | Terpyridine chelating agents |
| US4957939A (en) | 1981-07-24 | 1990-09-18 | Schering Aktiengesellschaft | Sterile pharmaceutical compositions of gadolinium chelates useful enhancing NMR imaging |
| EP0247156B1 (en) | 1985-11-18 | 1993-06-23 | Access Pharmaceuticals Inc. | Polychelating agents for image and spectral enhancement (and spectral shift) |
| EP0233607B1 (en) | 1986-02-18 | 1991-03-13 | E.R. Squibb & Sons, Inc. | [(2,2,2-Trichloroethoxy) methoxy]amine |
| US5064956A (en) | 1987-06-24 | 1991-11-12 | The Dow Chemical Company | Process for preparing mono-n-alkylated polyazamacrocycles |
| IT1224627B (it) | 1988-04-12 | 1990-10-04 | Guidotti & C Spa Labor | Ammidi di acidi ciclometilen_1,2_dicarbossilici adattivita' terapeutica, procedimenti per la loro preparazione e composizioni farmaceutiche che le contengono. |
| US5087440A (en) | 1989-07-31 | 1992-02-11 | Salutar, Inc. | Heterocyclic derivatives of DTPA used for magnetic resonance imaging |
| US5089043A (en) | 1989-11-09 | 1992-02-18 | Shionogi & Co., Ltd. | Heterocyclic oxy-phenoxyacetic acid derivatives and their use as herbicides |
| JPH0491070A (ja) | 1990-08-06 | 1992-03-24 | Kanebo Ltd | カリックスアレーン誘導体 |
| US5274129A (en) | 1991-06-12 | 1993-12-28 | Idaho Research Foundation, Inc. | Hydroxamic acid crown ethers |
| GB9115375D0 (en) | 1991-07-17 | 1991-09-04 | Salutar Inc | Compounds |
| US5639746A (en) | 1994-12-29 | 1997-06-17 | The Procter & Gamble Company | Hydroxamic acid-containing inhibitors of matrix metalloproteases |
| TW319763B (https=) | 1995-02-01 | 1997-11-11 | Epix Medical Inc | |
| EP0955044B1 (en) | 1995-06-26 | 2005-11-16 | Chelator LLC | Method of inhibiting bacterial or fungal growth using a complexing agent |
| DE19914101C1 (de) * | 1999-03-22 | 2000-10-12 | Schering Ag | Perfluoralkylamide, ihre Herstellung und ihre Verwendung in der Diagnostik |
| US6461587B1 (en) | 1999-03-22 | 2002-10-08 | Schering Aktiengesellschaft | Perfluoroalkylamides, their production and their use in diagnosis |
| US6989139B2 (en) | 2000-02-15 | 2006-01-24 | Bristol-Myers Squibb Pharma Company | Matrix metalloproteinase inhibitors |
| US6656448B1 (en) | 2000-02-15 | 2003-12-02 | Bristol-Myers Squibb Pharma Company | Matrix metalloproteinase inhibitors |
| US20020002152A1 (en) * | 2000-04-14 | 2002-01-03 | Craig Richard A. | Hydrazide and alkoxyamide angiogenesis inhibitors |
| EP1377321A4 (en) | 2001-02-23 | 2006-01-11 | Bristol Myers Squibb Co | RECOVERY ANTAGONISTS RECEIVING DETECTABLE MACROPHAGE RECEPTORS FOR THE IDENTIFICATION OF ATHEROSCLEROSIS AND VULNERABLE PLAQUE BY IMAGING |
| JP4590157B2 (ja) | 2001-03-21 | 2010-12-01 | アイシス イノヴェイション リミテッド | アッセイ、方法および手段 |
| TWI240632B (en) | 2001-07-30 | 2005-10-01 | Epix Medical Inc | Purified peptides for peptide-based multimeric targeted contrast agents |
| WO2005001415A2 (en) | 2003-05-23 | 2005-01-06 | Epix Pharmaceuticals, Inc. | Optically pure and enriched isomers of chelating ligands and contrast agents |
| WO2005020973A2 (en) | 2003-08-29 | 2005-03-10 | The University Of Houston System | Compositions having antimycrobial activity including a hydroxamate or a hydroxamate and a hydroxylamine |
| US20050106100A1 (en) | 2003-09-03 | 2005-05-19 | Harris Thomas D. | Compounds containing matrix metalloproteinase substrates and methods of their use |
| WO2005084179A2 (en) * | 2003-12-01 | 2005-09-15 | Immunomedics, Inc. | Improved method for preparing conjugates of proteins and chelating agents |
| US20070142417A1 (en) | 2005-05-11 | 2007-06-21 | Aventis Pharmaceuticals Inc | Substantially Pure 2-{[2-(2-Methylamino-Pyrimidin-4-YL)-1H-Indole-5-Carbonyl]-Amino}-3-Phenylpyridin-2-YL-Amino)-Propionic Acid as an IkB Kinase Inhibitor |
| WO2007005491A1 (en) | 2005-06-30 | 2007-01-11 | Bristol-Myers Squibb Pharma Company | Hydrazide conjugates as imaging agents |
| US7618957B2 (en) | 2005-07-15 | 2009-11-17 | Bayer Schering Pharma Aktiengesellschaft | Perfluoroalkyl-containing complexes, process for their production as well as their use |
| US8361438B2 (en) | 2008-01-08 | 2013-01-29 | Lantheus Medical Imaging, Inc. | N-alkoxyamide conjugates as imaging agents |
| CA2803520C (en) | 2009-07-08 | 2019-10-22 | Lantheus Medical Imaging, Inc. | N-alkoxyamide conjugates as imaging agents |
-
2010
- 2010-07-08 CA CA2803520A patent/CA2803520C/en not_active Expired - Fee Related
- 2010-07-08 WO PCT/US2010/001926 patent/WO2011005322A2/en not_active Ceased
- 2010-07-08 US US13/382,689 patent/US8877157B2/en active Active
- 2010-07-08 JP JP2012519544A patent/JP5676600B2/ja not_active Expired - Fee Related
- 2010-07-08 EP EP10797455.2A patent/EP2451776B1/en active Active
- 2010-07-08 CN CN201080040596.8A patent/CN102781909B/zh not_active Expired - Fee Related
- 2010-07-08 AU AU2010271097A patent/AU2010271097B2/en not_active Ceased
-
2014
- 2014-09-22 US US14/492,896 patent/US9393329B2/en active Active
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