JP2012532868A5 - - Google Patents
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- Publication number
- JP2012532868A5 JP2012532868A5 JP2012519544A JP2012519544A JP2012532868A5 JP 2012532868 A5 JP2012532868 A5 JP 2012532868A5 JP 2012519544 A JP2012519544 A JP 2012519544A JP 2012519544 A JP2012519544 A JP 2012519544A JP 2012532868 A5 JP2012532868 A5 JP 2012532868A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- substituted
- aryl
- compound
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22394609P | 2009-07-08 | 2009-07-08 | |
| US61/223,946 | 2009-07-08 | ||
| PCT/US2010/001926 WO2011005322A2 (en) | 2009-07-08 | 2010-07-08 | N-alkoxyamide conjugates as imaging agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012532868A JP2012532868A (ja) | 2012-12-20 |
| JP2012532868A5 true JP2012532868A5 (https=) | 2013-08-29 |
| JP5676600B2 JP5676600B2 (ja) | 2015-02-25 |
Family
ID=43429724
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012519544A Expired - Fee Related JP5676600B2 (ja) | 2009-07-08 | 2010-07-08 | 造影剤としてのｎ−アルコキシアミド抱合体 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US8877157B2 (https=) |
| EP (1) | EP2451776B1 (https=) |
| JP (1) | JP5676600B2 (https=) |
| CN (1) | CN102781909B (https=) |
| AU (1) | AU2010271097B2 (https=) |
| CA (1) | CA2803520C (https=) |
| WO (1) | WO2011005322A2 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2405655T3 (es) | 2006-12-26 | 2013-05-31 | Lantheus Medical Imaging, Inc. | N-[3-bromo-4-(3-[18F]fluoropropoxi)-bencil]-guanidina para la formación de imágenes de la inervación cardíaca |
| JP5730581B2 (ja) | 2008-01-08 | 2015-06-10 | ランセウス メディカル イメージング， インコーポレイテッド | 造影剤としてのｎ−アルコキシアミド抱合体 |
| WO2011005322A2 (en) | 2009-07-08 | 2011-01-13 | Lantheus Medical Imaging, Inc. | N-alkoxyamide conjugates as imaging agents |
| ES2763815T3 (es) | 2010-05-11 | 2020-06-01 | Lantheus Medical Imaging Inc | Composiciones, métodos y sistemas para la síntesis y uso de agentes de formación de imágenes |
| GB201102189D0 (en) * | 2011-02-08 | 2011-03-23 | King S College London | Materials and methods relating to cardiovascular imaging |
| CN108484449A (zh) * | 2011-09-09 | 2018-09-04 | 蓝瑟斯医学影像公司 | 用于合成和使用显像剂的组合物、方法和系统 |
| WO2013070471A1 (en) | 2011-11-11 | 2013-05-16 | Lantheus Medical Imaging, Inc. | Evaluation of presence of and vulnerability to atrial fibrillation and other indications using matrix metalloproteinase-based imaging |
| AU2013203000B9 (en) | 2012-08-10 | 2017-02-02 | Lantheus Medical Imaging, Inc. | Compositions, methods, and systems for the synthesis and use of imaging agents |
| TWI780082B (zh) | 2016-11-18 | 2022-10-11 | 日商安斯泰來製藥股份有限公司 | 新穎抗人類ＭＵＣ１抗體Ｆａｂ片段 |
| TWI795415B (zh) | 2017-07-07 | 2023-03-11 | 日商安斯泰來製藥股份有限公司 | 新穎的抗人類ＣＥＡＣＡＭ５抗體Ｆａｂ片段 |
| BR112020023420A8 (pt) | 2018-05-17 | 2022-07-05 | Astellas Pharma Inc | Complexo tendo fragmento fab de anticorpo anti-muc1 humano, peptídeo ligador e/ou ligante |
| SG11202103670XA (en) | 2018-10-10 | 2021-05-28 | Astellas Pharma Inc | Pharmaceutical composition containing tagged site-antihuman antibody fab fragment complex |
| MX2021008230A (es) * | 2019-01-07 | 2021-08-11 | Astellas Pharma Inc | Conjugado que comprende ligando y fragmento fab de anticuerpo ceacam5. |
| CN117486698B (zh) * | 2023-10-30 | 2025-08-19 | 国网安徽省电力有限公司电力科学研究院 | 烯醇硅醚类化合物制备c-c键偶联产物的方法与sf6的应用 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5122885A (en) | 1974-08-13 | 1976-02-23 | Sagami Chem Res | Ashiru ll aminosan oo chikanhidorokisamidono seizohoho |
| JPS5910322B2 (ja) * | 1975-07-30 | 1984-03-08 | 三井東圧化学株式会社 | 殺草剤 |
| US4859777A (en) | 1981-07-01 | 1989-08-22 | Eastman Kodak Company | Terpyridine chelating agents |
| US4957939A (en) | 1981-07-24 | 1990-09-18 | Schering Aktiengesellschaft | Sterile pharmaceutical compositions of gadolinium chelates useful enhancing NMR imaging |
| AU6621586A (en) | 1985-11-18 | 1987-06-02 | University Of Texas System, The | Polychelating agents for image and spectral enhancement (and spectral shift) |
| EP0233607B1 (en) | 1986-02-18 | 1991-03-13 | E.R. Squibb & Sons, Inc. | [(2,2,2-Trichloroethoxy) methoxy]amine |
| US5064956A (en) | 1987-06-24 | 1991-11-12 | The Dow Chemical Company | Process for preparing mono-n-alkylated polyazamacrocycles |
| IT1224627B (it) | 1988-04-12 | 1990-10-04 | Guidotti & C Spa Labor | Ammidi di acidi ciclometilen_1,2_dicarbossilici adattivita' terapeutica, procedimenti per la loro preparazione e composizioni farmaceutiche che le contengono. |
| US5087440A (en) | 1989-07-31 | 1992-02-11 | Salutar, Inc. | Heterocyclic derivatives of DTPA used for magnetic resonance imaging |
| US5089043A (en) | 1989-11-09 | 1992-02-18 | Shionogi & Co., Ltd. | Heterocyclic oxy-phenoxyacetic acid derivatives and their use as herbicides |
| JPH0491070A (ja) | 1990-08-06 | 1992-03-24 | Kanebo Ltd | カリックスアレーン誘導体 |
| US5274129A (en) | 1991-06-12 | 1993-12-28 | Idaho Research Foundation, Inc. | Hydroxamic acid crown ethers |
| GB9115375D0 (en) | 1991-07-17 | 1991-09-04 | Salutar Inc | Compounds |
| US5639746A (en) | 1994-12-29 | 1997-06-17 | The Procter & Gamble Company | Hydroxamic acid-containing inhibitors of matrix metalloproteases |
| TW319763B (https=) | 1995-02-01 | 1997-11-11 | Epix Medical Inc | |
| JP3356289B2 (ja) * | 1995-06-26 | 2002-12-16 | コンキャット リミティド | 第一遷移系列元素に対してキレート化親和性および選択性のある化合物とその医療および診断への使用 |
| DE19914101C1 (de) * | 1999-03-22 | 2000-10-12 | Schering Ag | Perfluoralkylamide, ihre Herstellung und ihre Verwendung in der Diagnostik |
| US6461587B1 (en) | 1999-03-22 | 2002-10-08 | Schering Aktiengesellschaft | Perfluoroalkylamides, their production and their use in diagnosis |
| US6989139B2 (en) | 2000-02-15 | 2006-01-24 | Bristol-Myers Squibb Pharma Company | Matrix metalloproteinase inhibitors |
| US6656448B1 (en) * | 2000-02-15 | 2003-12-02 | Bristol-Myers Squibb Pharma Company | Matrix metalloproteinase inhibitors |
| US20020002152A1 (en) | 2000-04-14 | 2002-01-03 | Craig Richard A. | Hydrazide and alkoxyamide angiogenesis inhibitors |
| AU2002254000A1 (en) | 2001-02-23 | 2002-09-12 | Bristol-Myers Squibb Pharma Company | Labeled macrophage scavenger receptor antagonists for imaging atherosclerosis and vulnerable plaque |
| JP4590157B2 (ja) | 2001-03-21 | 2010-12-01 | アイシス イノヴェイション リミテッド | アッセイ、方法および手段 |
| TWI240632B (en) | 2001-07-30 | 2005-10-01 | Epix Medical Inc | Purified peptides for peptide-based multimeric targeted contrast agents |
| WO2005001415A2 (en) * | 2003-05-23 | 2005-01-06 | Epix Pharmaceuticals, Inc. | Optically pure and enriched isomers of chelating ligands and contrast agents |
| US7662856B2 (en) | 2003-08-29 | 2010-02-16 | The University Of Houston System | Compositions having antimycrobial activity including a hydroxamate or a hydroxamate and a hydroxlyamine |
| US20050106100A1 (en) | 2003-09-03 | 2005-05-19 | Harris Thomas D. | Compounds containing matrix metalloproteinase substrates and methods of their use |
| WO2005084179A2 (en) * | 2003-12-01 | 2005-09-15 | Immunomedics, Inc. | Improved method for preparing conjugates of proteins and chelating agents |
| US20070142417A1 (en) | 2005-05-11 | 2007-06-21 | Aventis Pharmaceuticals Inc | Substantially Pure 2-{[2-(2-Methylamino-Pyrimidin-4-YL)-1H-Indole-5-Carbonyl]-Amino}-3-Phenylpyridin-2-YL-Amino)-Propionic Acid as an IkB Kinase Inhibitor |
| WO2007005491A1 (en) | 2005-06-30 | 2007-01-11 | Bristol-Myers Squibb Pharma Company | Hydrazide conjugates as imaging agents |
| US7618957B2 (en) * | 2005-07-15 | 2009-11-17 | Bayer Schering Pharma Aktiengesellschaft | Perfluoroalkyl-containing complexes, process for their production as well as their use |
| JP5730581B2 (ja) | 2008-01-08 | 2015-06-10 | ランセウス メディカル イメージング， インコーポレイテッド | 造影剤としてのｎ−アルコキシアミド抱合体 |
| WO2011005322A2 (en) | 2009-07-08 | 2011-01-13 | Lantheus Medical Imaging, Inc. | N-alkoxyamide conjugates as imaging agents |
-
2010
- 2010-07-08 WO PCT/US2010/001926 patent/WO2011005322A2/en not_active Ceased
- 2010-07-08 US US13/382,689 patent/US8877157B2/en active Active
- 2010-07-08 AU AU2010271097A patent/AU2010271097B2/en not_active Ceased
- 2010-07-08 JP JP2012519544A patent/JP5676600B2/ja not_active Expired - Fee Related
- 2010-07-08 EP EP10797455.2A patent/EP2451776B1/en active Active
- 2010-07-08 CN CN201080040596.8A patent/CN102781909B/zh not_active Expired - Fee Related
- 2010-07-08 CA CA2803520A patent/CA2803520C/en not_active Expired - Fee Related
-
2014
- 2014-09-22 US US14/492,896 patent/US9393329B2/en active Active
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