|
US3854480A
(en)
|
1969-04-01 |
1974-12-17 |
Alza Corp |
Drug-delivery system
|
|
US4675189A
(en)
|
1980-11-18 |
1987-06-23 |
Syntex (U.S.A.) Inc. |
Microencapsulation of water soluble active polypeptides
|
|
EP0073856A1
(en)
*
|
1981-08-28 |
1983-03-16 |
Gist-Brocades N.V. |
Infectious-bronchitis vaccines for poultry, combined infectious-bronchitis vaccines, process for preparing such vaccines, process for preventing infectious bronchitis and infectious-bronchitis virus strain
|
|
US4436727A
(en)
|
1982-05-26 |
1984-03-13 |
Ribi Immunochem Research, Inc. |
Refined detoxified endotoxin product
|
|
US4452775A
(en)
|
1982-12-03 |
1984-06-05 |
Syntex (U.S.A.) Inc. |
Cholesterol matrix delivery system for sustained release of macromolecules
|
|
NL8301996A
(nl)
*
|
1983-06-06 |
1985-01-02 |
Duphar Int Res |
Werkwijze ter bereiding van geadjuveerde levende vaccins en aldus verkregen geadjuveerde levende vaccins.
|
|
US4596556A
(en)
|
1985-03-25 |
1986-06-24 |
Bioject, Inc. |
Hypodermic injection apparatus
|
|
US5075109A
(en)
|
1986-10-24 |
1991-12-24 |
Southern Research Institute |
Method of potentiating an immune response
|
|
CA1331443C
(en)
|
1987-05-29 |
1994-08-16 |
Charlotte A. Kensil |
Saponin adjuvant
|
|
US5057540A
(en)
*
|
1987-05-29 |
1991-10-15 |
Cambridge Biotech Corporation |
Saponin adjuvant
|
|
US4895452A
(en)
*
|
1988-03-03 |
1990-01-23 |
Micro-Pak, Inc. |
Method and apparatus for producing lipid vesicles
|
|
US5133974A
(en)
|
1989-05-05 |
1992-07-28 |
Kv Pharmaceutical Company |
Extended release pharmaceutical formulations
|
|
US5103497A
(en)
|
1989-11-14 |
1992-04-07 |
Hicks John W |
Flying spot endoscope
|
|
EP0468520A3
(en)
|
1990-07-27 |
1992-07-01 |
Mitsui Toatsu Chemicals, Inc. |
Immunostimulatory remedies containing palindromic dna sequences
|
|
US5389369A
(en)
|
1991-02-21 |
1995-02-14 |
Exoxemis, Inc. |
Halo peroxidase containing compositions for killing yeast and sporular microorganisms
|
|
JP3507486B2
(ja)
|
1991-03-15 |
2004-03-15 |
アムジエン・インコーポレーテツド |
顆粒球コロニー刺激因子の肺内投与
|
|
IL101715A
(en)
|
1991-05-02 |
2005-06-19 |
Amgen Inc |
Recombinant dna-derived cholera toxin subunit analogs
|
|
IT1247472B
(it)
|
1991-05-31 |
1994-12-17 |
Fidia Spa |
Processo per la preparazione di microsfere contenenti componenti biologicamente attivi.
|
|
DK0597960T3
(da)
|
1991-08-10 |
1999-09-13 |
Medical Res Council |
Behandling af cellepopulationer
|
|
US5565332A
(en)
|
1991-09-23 |
1996-10-15 |
Medical Research Council |
Production of chimeric antibodies - a combinatorial approach
|
|
US6350784B1
(en)
*
|
1996-02-12 |
2002-02-26 |
Meryl J. Squires |
Antimicrobial prevention and treatment of human immunedeficiency virus and other infectious diseases
|
|
US5407686A
(en)
|
1991-11-27 |
1995-04-18 |
Sidmak Laboratories, Inc. |
Sustained release composition for oral administration of active ingredient
|
|
CA2085827C
(en)
|
1991-12-23 |
2003-10-14 |
Lucas A. T. Hilgers |
Adjuvant composition containing synthetic hydrophobic lipopolysaccharide
|
|
IT1253009B
(it)
|
1991-12-31 |
1995-07-10 |
Sclavo Ricerca S R L |
Mutanti immunogenici detossificati della tossina colerica e della tossina lt, loro preparazione ed uso per la preparazione di vaccini
|
|
EP0761231B1
(en)
|
1992-06-25 |
2000-01-12 |
SMITHKLINE BEECHAM BIOLOGICALS s.a. |
Vaccine composition containing adjuvants
|
|
EP0672142B1
(en)
|
1992-12-04 |
2001-02-28 |
Medical Research Council |
Multivalent and multispecific binding proteins, their manufacture and use
|
|
DK17093D0
(da)
*
|
1993-02-15 |
1993-02-15 |
Lyfjathroun H F |
Farmaceutisk praeparat til topisk administrering af antigener og/eller vacciner til pattedyr via slimhinder
|
|
ES2162139T5
(es)
|
1993-03-23 |
2008-05-16 |
Smithkline Beecham Biologicals S.A. |
Composiciones de vacuna que contienen monofosforil-lipido a 3-o-desacilado.
|
|
US5951988A
(en)
*
|
1993-03-30 |
1999-09-14 |
University Of Saskatchewan |
Adjuvant formulation with enhanced immunogenic activity, and related compositions and methods
|
|
US5576016A
(en)
*
|
1993-05-18 |
1996-11-19 |
Pharmos Corporation |
Solid fat nanoemulsions as drug delivery vehicles
|
|
US7223410B1
(en)
*
|
1994-08-05 |
2007-05-29 |
Sanofi Pasteur Limited |
Inactivated respiratory syncytial viral vaccines
|
|
US5961970A
(en)
*
|
1993-10-29 |
1999-10-05 |
Pharmos Corporation |
Submicron emulsions as vaccine adjuvants
|
|
CN1055093C
(zh)
|
1993-11-17 |
2000-08-02 |
实验室奥姆公司 |
葡糖胺二糖类、其制备方法和用途、以及含有这些二糖的药物组合物
|
|
GB9326253D0
(en)
|
1993-12-23 |
1994-02-23 |
Smithkline Beecham Biolog |
Vaccines
|
|
US5451569A
(en)
|
1994-04-19 |
1995-09-19 |
Hong Kong University Of Science And Technology R & D Corporation Limited |
Pulmonary drug delivery system
|
|
DE69527624T2
(de)
*
|
1994-05-20 |
2003-04-03 |
Novavax, Inc. |
Antimikrobielle öl-in-wasser-emulsionen
|
|
US5549901A
(en)
|
1994-05-20 |
1996-08-27 |
Novavax, Inc. |
Antimicrobial oil-in-water emulsions
|
|
US5547677A
(en)
*
|
1994-05-20 |
1996-08-20 |
Novavax, Inc. |
Antimicrobial oil-in-water emulsions
|
|
EP0772619B2
(en)
|
1994-07-15 |
2010-12-08 |
The University of Iowa Research Foundation |
Immunomodulatory oligonucleotides
|
|
AUPM873294A0
(en)
|
1994-10-12 |
1994-11-03 |
Csl Limited |
Saponin preparations and use thereof in iscoms
|
|
KR100201352B1
(ko)
*
|
1995-03-16 |
1999-06-15 |
성재갑 |
단일주사 백신 제형
|
|
UA56132C2
(uk)
|
1995-04-25 |
2003-05-15 |
Смітклайн Бічем Байолоджікалс С.А. |
Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини
|
|
US5736152A
(en)
|
1995-10-27 |
1998-04-07 |
Atrix Laboratories, Inc. |
Non-polymeric sustained release delivery system
|
|
US5662957A
(en)
*
|
1996-05-03 |
1997-09-02 |
Novavax, Inc. |
Oil containing lipid vesicles with marine applications
|
|
US5700679A
(en)
*
|
1996-06-07 |
1997-12-23 |
Novavax, Inc. |
Lipid vesicles having a bilayer containing a surfactant with anti-viral and spermicidal activity
|
|
DE69719761T2
(de)
|
1996-06-18 |
2003-12-18 |
Alza Corp., Palo Alto |
Vorrichtung zur verbesserung der transdermalen verabreichung von medikamenten oder der abnahme von körperflüssigkeiten
|
|
ATE292980T1
(de)
|
1996-10-11 |
2005-04-15 |
Univ California |
Immunostimulierende oligonucleotidekonjugate
|
|
US5980898A
(en)
|
1996-11-14 |
1999-11-09 |
The United States Of America As Represented By The U.S. Army Medical Research & Material Command |
Adjuvant for transcutaneous immunization
|
|
DK0957972T3
(da)
|
1996-12-20 |
2003-07-21 |
Alza Corp |
Anordning og fremgangsmåde til at forøge transdermal middelflux
|
|
US6627198B2
(en)
*
|
1997-03-13 |
2003-09-30 |
Corixa Corporation |
Fusion proteins of Mycobacterium tuberculosis antigens and their uses
|
|
US6491919B2
(en)
*
|
1997-04-01 |
2002-12-10 |
Corixa Corporation |
Aqueous immunologic adjuvant compostions of monophosphoryl lipid A
|
|
US5993412A
(en)
|
1997-05-19 |
1999-11-30 |
Bioject, Inc. |
Injection apparatus
|
|
GB9711990D0
(en)
|
1997-06-11 |
1997-08-06 |
Smithkline Beecham Biolog |
Vaccine
|
|
EP1009429B1
(en)
|
1997-08-29 |
2009-07-08 |
Antigenics Inc. |
Compositions comprising the adjuvant qs-21 and polysorbate or cyclodextrin as excipient
|
|
GB9718901D0
(en)
|
1997-09-05 |
1997-11-12 |
Smithkline Beecham Biolog |
Vaccine
|
|
DE69838992T2
(de)
|
1997-09-05 |
2008-12-24 |
Glaxosmithkline Biologicals S.A., Rixensart |
Öl-in-Wasser Emulsionen mit Saponinen
|
|
EP1035867A1
(en)
|
1997-12-02 |
2000-09-20 |
Powderject Vaccines, Inc. |
Transdermal delivery of particulate vaccine compositions
|
|
US6015832A
(en)
|
1997-12-31 |
2000-01-18 |
The Regents Of The University Of Michigan |
Methods of inactivating bacteria including bacterial spores
|
|
US6814968B1
(en)
*
|
1998-06-04 |
2004-11-09 |
Vanderbilt University |
Inhibition of viral infection and spread with viral and RhoA-derived peptides
|
|
CZ301212B6
(cs)
*
|
1998-10-16 |
2009-12-09 |
Smithkline Beecham Biologicals S. A. |
Vakcinacní prostredek
|
|
DE69942774D1
(de)
*
|
1999-02-26 |
2010-10-28 |
Novartis Vaccines & Diagnostic |
Verwendung von bioadhaesiven und adjuvantien für die mukosale anwendung von antigenen
|
|
JP2002537102A
(ja)
*
|
1999-02-26 |
2002-11-05 |
カイロン コーポレイション |
吸着された高分子および微粒子を有するミクロエマルジョン
|
|
GB9909077D0
(en)
*
|
1999-04-20 |
1999-06-16 |
Smithkline Beecham Biolog |
Novel compositions
|
|
US6506803B1
(en)
*
|
1999-04-28 |
2003-01-14 |
Regents Of The University Of Michigan |
Methods of preventing and treating microbial infections
|
|
US6559189B2
(en)
|
1999-04-28 |
2003-05-06 |
Regents Of The University Of Michigan |
Non-toxic antimicrobial compositions and methods of use
|
|
US6635676B2
(en)
*
|
1999-04-28 |
2003-10-21 |
Regents Of The University Of Michigan |
Non-toxic antimicrobial compositions and methods of use
|
|
US7767216B2
(en)
|
1999-04-28 |
2010-08-03 |
The Regents Of The University Of Michigan |
Antimicrobial compositions and methods of use
|
|
US6558695B2
(en)
*
|
1999-12-16 |
2003-05-06 |
Dermatrends, Inc. |
Topical and transdermal administration of peptidyl drugs using hydroxide releasing agents as permeation enhancers
|
|
KR100732110B1
(ko)
*
|
1999-12-30 |
2007-06-27 |
킴벌리-클라크 월드와이드, 인크. |
항균성 흡수용품, 및 그의 제조 및 사용 방법
|
|
US6651655B1
(en)
|
2000-01-18 |
2003-11-25 |
Quadrant Technologies Limited |
Inhaled vaccines
|
|
US20020155084A1
(en)
*
|
2000-06-02 |
2002-10-24 |
The Regents Of The University Of The Michigan |
Nanoemulsion formulations
|
|
US6565873B1
(en)
*
|
2000-10-25 |
2003-05-20 |
Salvona Llc |
Biodegradable bioadhesive controlled release system of nano-particles for oral care products
|
|
JP2006512401A
(ja)
*
|
2001-06-05 |
2006-04-13 |
ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン |
ナノエマルジョンワクチン
|
|
CA2471968C
(en)
*
|
2001-10-06 |
2013-07-23 |
Merial Limited |
Immunostimulatory nucleic acids and use thereof
|
|
US20050208083A1
(en)
*
|
2003-06-04 |
2005-09-22 |
Nanobio Corporation |
Compositions for inactivating pathogenic microorganisms, methods of making the compositons, and methods of use thereof
|
|
JP2006528647A
(ja)
*
|
2003-07-24 |
2006-12-21 |
メリアル リミテッド |
新規ワクチン製剤
|
|
US20060286124A1
(en)
*
|
2004-06-30 |
2006-12-21 |
Id Biomedical Corporation Of Quebec |
Vaccine compositions and methods of treating coronavirus infection
|
|
WO2006121464A2
(en)
*
|
2004-11-05 |
2006-11-16 |
Intradigm Corporation |
Compositions for treating respiratory viral infections and their use
|
|
US20060204469A1
(en)
*
|
2005-03-09 |
2006-09-14 |
Eric Spengler |
Stable mixed emulsions
|
|
CA2618974C
(en)
*
|
2005-08-09 |
2014-01-28 |
Nanobio Corporation |
Nanoemulsion compositions having anti-inflammatory activity
|
|
US20070292688A1
(en)
*
|
2005-08-18 |
2007-12-20 |
Eastman Kodak Company |
Silylamine modified nanoparticulate carriers
|
|
US20080039295A1
(en)
*
|
2006-08-14 |
2008-02-14 |
Zeev Steinmetz |
Method and device to enable and assist the elderly and females to exercise their abdominal and lower back muscles
|
|
WO2008137747A1
(en)
*
|
2007-05-02 |
2008-11-13 |
The Regents Of The University Of Michigan |
Nanoemulsion therapeutic compositions and methods of using the same
|
|
AU2009293595A1
(en)
*
|
2008-05-23 |
2010-03-25 |
The Regents Of The University Of Michigan |
Nanoemulsion adjuvants
|
|
EP2293813A4
(en)
*
|
2008-05-23 |
2012-07-11 |
Univ Michigan |
NANO EMULSION VACCINES
|