JP2012529281A - 抗ＥｐＣＡＭ抗体 - Google Patents
抗ＥｐＣＡＭ抗体 Download PDFInfo
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/734—Complement-dependent cytotoxicity [CDC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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- General Chemical & Material Sciences (AREA)
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- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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| US18538709P | 2009-06-09 | 2009-06-09 | |
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| US61/185,387 | 2009-06-09 | ||
| PCT/GB2010/050969 WO2010142990A1 (en) | 2009-06-09 | 2010-06-09 | ANTI-EpCAM ANTIBODIES |
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| EP (1) | EP2440580A1 (enExample) |
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Cited By (3)
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| JP2020515262A (ja) * | 2017-03-29 | 2020-05-28 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | 共刺激ｔｎｆ受容体のための二重特異性抗原結合分子 |
| JP2022506072A (ja) * | 2018-10-26 | 2022-01-17 | イミュノジェン， インコーポレイテッド | ＥｐＣＡＭ抗体、活性化可能抗体、および免疫複合体、ならびにそれらの使用 |
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| EP2436397B1 (en) | 2009-05-29 | 2017-05-10 | Chugai Seiyaku Kabushiki Kaisha | Pharmaceutical composition containing antagonist of egf family ligand as component |
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- 2010-06-09 WO PCT/GB2010/050969 patent/WO2010142990A1/en not_active Ceased
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- 2010-06-09 BR BRPI1011005A patent/BRPI1011005A2/pt not_active IP Right Cessation
- 2010-06-09 CN CN2010800351667A patent/CN102549017A/zh active Pending
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016510755A (ja) * | 2013-03-06 | 2016-04-11 | メリマック ファーマシューティカルズ インコーポレーティッド | 抗Ｃ−ＭＥＴタンデムＦｃ二重特異性抗体 |
| JP2020515262A (ja) * | 2017-03-29 | 2020-05-28 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | 共刺激ｔｎｆ受容体のための二重特異性抗原結合分子 |
| JP7196094B2 (ja) | 2017-03-29 | 2022-12-26 | エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト | 共刺激ｔｎｆ受容体のための二重特異性抗原結合分子 |
| US11639394B2 (en) | 2017-03-29 | 2023-05-02 | Hoffmann-La Roche Inc. | Bispecific antigen binding molecule for a costimulatory TNF receptor |
| JP2022506072A (ja) * | 2018-10-26 | 2022-01-17 | イミュノジェン， インコーポレイテッド | ＥｐＣＡＭ抗体、活性化可能抗体、および免疫複合体、ならびにそれらの使用 |
| JP7592009B2 (ja) | 2018-10-26 | 2024-11-29 | イミュノジェン， インコーポレイテッド | ＥｐＣＡＭ抗体、活性化可能抗体、および免疫複合体、ならびにそれらの使用 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102549017A (zh) | 2012-07-04 |
| EP2440580A1 (en) | 2012-04-18 |
| GB0909904D0 (en) | 2009-07-22 |
| US8637017B2 (en) | 2014-01-28 |
| EA201171463A1 (ru) | 2012-07-30 |
| US20100310463A1 (en) | 2010-12-09 |
| WO2010142990A1 (en) | 2010-12-16 |
| BRPI1011005A2 (pt) | 2018-03-06 |
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