JP2012523437A5 - - Google Patents

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Publication number
JP2012523437A5
JP2012523437A5 JP2012504924A JP2012504924A JP2012523437A5 JP 2012523437 A5 JP2012523437 A5 JP 2012523437A5 JP 2012504924 A JP2012504924 A JP 2012504924A JP 2012504924 A JP2012504924 A JP 2012504924A JP 2012523437 A5 JP2012523437 A5 JP 2012523437A5
Authority
JP
Japan
Prior art keywords
methyl
isopropyl
amino
carboxylic acid
receptor agonist
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2012504924A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012523437A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2010/030760 external-priority patent/WO2010120695A2/en
Publication of JP2012523437A publication Critical patent/JP2012523437A/ja
Publication of JP2012523437A5 publication Critical patent/JP2012523437A5/ja
Pending legal-status Critical Current

Links

JP2012504924A 2009-04-13 2010-04-12 認知障害の治療のための5−ht4受容体アゴニスト化合物 Pending JP2012523437A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US16874109P 2009-04-13 2009-04-13
US61/168,741 2009-04-13
US29255910P 2010-01-06 2010-01-06
US61/292,559 2010-01-06
PCT/US2010/030760 WO2010120695A2 (en) 2009-04-13 2010-04-12 5-ht4 receptor agonist compounds for treatment of cognitive disorders

Publications (2)

Publication Number Publication Date
JP2012523437A JP2012523437A (ja) 2012-10-04
JP2012523437A5 true JP2012523437A5 (enExample) 2013-04-11

Family

ID=42237213

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012504924A Pending JP2012523437A (ja) 2009-04-13 2010-04-12 認知障害の治療のための5−ht4受容体アゴニスト化合物

Country Status (24)

Country Link
US (2) US8404711B2 (enExample)
EP (1) EP2419104B1 (enExample)
JP (1) JP2012523437A (enExample)
KR (1) KR20120017421A (enExample)
CN (2) CN102395371A (enExample)
AU (1) AU2010236734B2 (enExample)
BR (1) BRPI1013777A8 (enExample)
CA (1) CA2758321A1 (enExample)
CY (1) CY1119800T1 (enExample)
DK (1) DK2419104T3 (enExample)
ES (1) ES2654930T3 (enExample)
HR (1) HRP20180018T1 (enExample)
HU (1) HUE038141T2 (enExample)
IL (1) IL215660A0 (enExample)
LT (1) LT2419104T (enExample)
MX (1) MX2011010782A (enExample)
NO (1) NO2419104T3 (enExample)
PL (1) PL2419104T3 (enExample)
PT (1) PT2419104T (enExample)
RU (1) RU2569056C2 (enExample)
SI (1) SI2419104T1 (enExample)
SM (1) SMT201800036T1 (enExample)
WO (1) WO2010120695A2 (enExample)
ZA (1) ZA201107490B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10164139A1 (de) 2001-12-27 2003-07-10 Bayer Ag 2-Heteroarylcarbonsäureamide
AU2009316557B2 (en) 2008-11-19 2015-08-27 Envivo Pharmaceuticals, Inc. Treatment of cognitive disorders with (R)-7-chloro-N-(quinuclidin-3-yl) benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof
BRPI1014793A2 (pt) * 2009-05-11 2016-04-05 Envivo Pharmaceuticals Inc tratamento de distúrbios de cognição com determinados receptores de ácido alfa-7-nicotínico em combinação com inibidores de acetil-colinesterase
CA2799744C (en) 2010-05-17 2020-01-28 Envivo Pharmaceuticals, Inc. A crystalline form of (r)-7-chloro-n-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide hydrochloride monohydrate
US9585877B2 (en) 2012-05-08 2017-03-07 Forum Pharmaceuticals, Inc. Methods of maintaining, treating or improving cognitive function
US10874701B2 (en) 2012-08-16 2020-12-29 University-Industry Cooperation Group Of Kyung Hee University Lactic acid bacteria capable of preventing and/or treating senescence and dementia
CN104781390B (zh) 2012-08-16 2017-07-28 庆熙大学校产学协力团 具有对衰老及痴呆的预防和/或治疗活性的乳酸菌
PT3630098T (pt) 2017-05-24 2021-04-21 H Lundbeck As Combinação de um antagonista do receptor 5-ht6 e de um inibidor de acetilcolinesterase para utilização no tratamento da doença de alzheimer numa subpopulação de pacientes portadores de alelos apoe4
RU2019135261A (ru) 2017-06-01 2021-07-09 Эйсай Ар Энд Ди Менеджмент Ко., Лтд. Фармацевтическая композиция, содержащая ингибитор pde9
MX393052B (es) 2017-06-02 2025-03-24 Fujifilm Toyama Chemical Co Ltd Agente para prevenir o tratar atrofia cerebral.
CA3069989C (en) 2017-07-31 2025-05-06 Alfasigma S.P.A. METHODS FOR TREATING GASTROPARESIA SYMPTOMS USING VELUSETRAG

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003525903A (ja) * 2000-03-03 2003-09-02 エーザイ株式会社 コリンエステラーゼ阻害剤の新規使用法
TWI351282B (en) * 2004-04-07 2011-11-01 Theravance Inc Quinolinone-carboxamide compounds as 5-ht4 recepto
US7598265B2 (en) 2004-09-30 2009-10-06 Epix Delaware, Inc. Compositions and methods for treating CNS disorders
TWI377206B (en) * 2005-04-06 2012-11-21 Theravance Inc Crystalline form of a quinolinone-carboxamide compound
MY147756A (en) 2005-05-25 2013-01-15 Theravance Inc Benzimidazole-carboxamide compounds as 5-ht4 receptor agonists

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