HUE038141T2 - 5-HT4 receptor agonisták és acetilkolinészteráz inhibitorok kombinációi kognitív rendellenességek kezelésére - Google Patents
5-HT4 receptor agonisták és acetilkolinészteráz inhibitorok kombinációi kognitív rendellenességek kezeléséreInfo
- Publication number
- HUE038141T2 HUE038141T2 HUE10713790A HUE10713790A HUE038141T2 HU E038141 T2 HUE038141 T2 HU E038141T2 HU E10713790 A HUE10713790 A HU E10713790A HU E10713790 A HUE10713790 A HU E10713790A HU E038141 T2 HUE038141 T2 HU E038141T2
- Authority
- HU
- Hungary
- Prior art keywords
- combinations
- treatment
- receptor agonists
- cognitive disorders
- acetylcholinesterase inhibitors
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16874109P | 2009-04-13 | 2009-04-13 | |
| US29255910P | 2010-01-06 | 2010-01-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE038141T2 true HUE038141T2 (hu) | 2018-10-29 |
Family
ID=42237213
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE10713790A HUE038141T2 (hu) | 2009-04-13 | 2010-04-12 | 5-HT4 receptor agonisták és acetilkolinészteráz inhibitorok kombinációi kognitív rendellenességek kezelésére |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US8404711B2 (hu) |
| EP (1) | EP2419104B1 (hu) |
| JP (1) | JP2012523437A (hu) |
| KR (1) | KR20120017421A (hu) |
| CN (2) | CN102395371A (hu) |
| AU (1) | AU2010236734B2 (hu) |
| BR (1) | BRPI1013777A8 (hu) |
| CA (1) | CA2758321A1 (hu) |
| CY (1) | CY1119800T1 (hu) |
| DK (1) | DK2419104T3 (hu) |
| ES (1) | ES2654930T3 (hu) |
| HR (1) | HRP20180018T1 (hu) |
| HU (1) | HUE038141T2 (hu) |
| IL (1) | IL215660A0 (hu) |
| LT (1) | LT2419104T (hu) |
| MX (1) | MX2011010782A (hu) |
| NO (1) | NO2419104T3 (hu) |
| PL (1) | PL2419104T3 (hu) |
| PT (1) | PT2419104T (hu) |
| RU (1) | RU2569056C2 (hu) |
| SI (1) | SI2419104T1 (hu) |
| WO (1) | WO2010120695A2 (hu) |
| ZA (1) | ZA201107490B (hu) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10164139A1 (de) | 2001-12-27 | 2003-07-10 | Bayer Ag | 2-Heteroarylcarbonsäureamide |
| CN105687190A (zh) | 2008-11-19 | 2016-06-22 | 福拉姆医药股份有限公司 | 用(R)-7-氯-N-(奎宁环-3-基)苯并[b]噻吩-2-甲酰胺及其可药用盐治疗认知障碍 |
| RU2011150248A (ru) * | 2009-05-11 | 2013-06-20 | Энвиво Фармасьютикалз, Инк. | Лечение когнитивных расстройств с определенными рецепторами альфа-7 никотиновой кислоты в комбинации с ингибиторами ацетилхолинэстеразы |
| AU2011256287B2 (en) | 2010-05-17 | 2016-11-10 | Envivo Pharmaceuticals, Inc. | A crystalline form of (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide hydrochloride monohydrate |
| RU2017136693A (ru) | 2012-05-08 | 2019-02-08 | Форум Фармасьютикалз, Инк. | Способы поддержания, лечения или улучшения когнитивной функции |
| WO2014027864A1 (ko) | 2012-08-16 | 2014-02-20 | 경희대학교 산학협력단 | 노화 및 치매의 예방 및/또는 치료 활성을 갖는 유산균 |
| US10874701B2 (en) | 2012-08-16 | 2020-12-29 | University-Industry Cooperation Group Of Kyung Hee University | Lactic acid bacteria capable of preventing and/or treating senescence and dementia |
| SI3630098T1 (sl) | 2017-05-24 | 2021-07-30 | H. Lundbeck A/S | Kombinacija antagonista receptorja 5-HT6 in zaviralca acetilholinesteraze za uporabo pri zdravljenju Alzheimerjeve bolezni pri podpulaciji pacientov, ki nosijo alele ApoE4 |
| US11484502B2 (en) | 2017-06-01 | 2022-11-01 | Eisai R&D Management Co., Ltd. | Pharmaceutical composition comprising PDE9 inhibitor |
| CN116473962A (zh) | 2017-06-02 | 2023-07-25 | 富士胶片富山化学株式会社 | 脑萎缩预防或治疗剂 |
| JP7431721B2 (ja) | 2017-07-31 | 2024-02-15 | セラヴァンス バイオファーマ アール＆ディー アイピー， エルエルシー | ベルセトラグを用いて胃不全麻痺の症状を治療する方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003525903A (ja) * | 2000-03-03 | 2003-09-02 | エーザイ株式会社 | コリンエステラーゼ阻害剤の新規使用法 |
| TWI351282B (en) * | 2004-04-07 | 2011-11-01 | Theravance Inc | Quinolinone-carboxamide compounds as 5-ht4 recepto |
| US7598265B2 (en) | 2004-09-30 | 2009-10-06 | Epix Delaware, Inc. | Compositions and methods for treating CNS disorders |
| TWI377206B (en) * | 2005-04-06 | 2012-11-21 | Theravance Inc | Crystalline form of a quinolinone-carboxamide compound |
| MY147756A (en) * | 2005-05-25 | 2013-01-15 | Theravance Inc | Benzimidazole-carboxamide compounds as 5-ht4 receptor agonists |
-
2010
- 2010-04-12 HU HUE10713790A patent/HUE038141T2/hu unknown
- 2010-04-12 KR KR1020117026729A patent/KR20120017421A/ko not_active Application Discontinuation
- 2010-04-12 MX MX2011010782A patent/MX2011010782A/es active IP Right Grant
- 2010-04-12 AU AU2010236734A patent/AU2010236734B2/en not_active Ceased
- 2010-04-12 DK DK10713790.3T patent/DK2419104T3/en active
- 2010-04-12 LT LTEP10713790.3T patent/LT2419104T/lt unknown
- 2010-04-12 ES ES10713790.3T patent/ES2654930T3/es active Active
- 2010-04-12 BR BRPI1013777A patent/BRPI1013777A8/pt not_active IP Right Cessation
- 2010-04-12 JP JP2012504924A patent/JP2012523437A/ja active Pending
- 2010-04-12 PT PT107137903T patent/PT2419104T/pt unknown
- 2010-04-12 CN CN2010800164976A patent/CN102395371A/zh active Pending
- 2010-04-12 CN CN201610257689.5A patent/CN105832735A/zh active Pending
- 2010-04-12 NO NO10713790A patent/NO2419104T3/no unknown
- 2010-04-12 PL PL10713790T patent/PL2419104T3/pl unknown
- 2010-04-12 RU RU2011146032/15A patent/RU2569056C2/ru not_active IP Right Cessation
- 2010-04-12 CA CA2758321A patent/CA2758321A1/en not_active Abandoned
- 2010-04-12 EP EP10713790.3A patent/EP2419104B1/en active Active
- 2010-04-12 SI SI201031632T patent/SI2419104T1/en unknown
- 2010-04-12 WO PCT/US2010/030760 patent/WO2010120695A2/en active Application Filing
- 2010-04-12 US US12/758,631 patent/US8404711B2/en active Active
-
2011
- 2011-10-10 IL IL215660A patent/IL215660A0/en unknown
- 2011-10-12 ZA ZA2011/07490A patent/ZA201107490B/en unknown
-
2013
- 2013-02-20 US US13/771,685 patent/US20140057939A1/en not_active Abandoned
-
2018
- 2018-01-05 HR HRP20180018TT patent/HRP20180018T1/hr unknown
- 2018-01-19 CY CY20181100069T patent/CY1119800T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI1013777A8 (pt) | 2017-09-19 |
| KR20120017421A (ko) | 2012-02-28 |
| PT2419104T (pt) | 2018-01-31 |
| US20140057939A1 (en) | 2014-02-27 |
| AU2010236734A8 (en) | 2012-02-16 |
| US20100261752A1 (en) | 2010-10-14 |
| LT2419104T (lt) | 2018-02-12 |
| JP2012523437A (ja) | 2012-10-04 |
| NO2419104T3 (hu) | 2018-04-07 |
| ZA201107490B (en) | 2012-06-27 |
| WO2010120695A3 (en) | 2010-12-02 |
| CN102395371A (zh) | 2012-03-28 |
| CA2758321A1 (en) | 2010-10-21 |
| SI2419104T1 (en) | 2018-03-30 |
| US8404711B2 (en) | 2013-03-26 |
| DK2419104T3 (en) | 2018-02-05 |
| RU2011146032A (ru) | 2013-05-20 |
| AU2010236734A1 (en) | 2011-11-03 |
| EP2419104B1 (en) | 2017-11-08 |
| ES2654930T3 (es) | 2018-02-15 |
| CY1119800T1 (el) | 2018-06-27 |
| WO2010120695A2 (en) | 2010-10-21 |
| RU2569056C2 (ru) | 2015-11-20 |
| IL215660A0 (en) | 2012-01-31 |
| EP2419104A2 (en) | 2012-02-22 |
| BRPI1013777A2 (pt) | 2016-04-05 |
| MX2011010782A (es) | 2012-01-20 |
| CN105832735A (zh) | 2016-08-10 |
| PL2419104T3 (pl) | 2018-04-30 |
| HRP20180018T1 (hr) | 2018-02-09 |
| AU2010236734B2 (en) | 2015-06-11 |
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