LT2419104T - 5-ht4 receptoriaus agonistų ir acetilcholinesterazės inhibitorių deriniai, skirti pažinimo sutrikimų gydymui - Google Patents
5-ht4 receptoriaus agonistų ir acetilcholinesterazės inhibitorių deriniai, skirti pažinimo sutrikimų gydymuiInfo
- Publication number
- LT2419104T LT2419104T LTEP10713790.3T LT10713790T LT2419104T LT 2419104 T LT2419104 T LT 2419104T LT 10713790 T LT10713790 T LT 10713790T LT 2419104 T LT2419104 T LT 2419104T
- Authority
- LT
- Lithuania
- Prior art keywords
- combinations
- treatment
- receptor agonists
- cognitive disorders
- acetylcholinesterase inhibitors
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16874109P | 2009-04-13 | 2009-04-13 | |
| US29255910P | 2010-01-06 | 2010-01-06 | |
| PCT/US2010/030760 WO2010120695A2 (en) | 2009-04-13 | 2010-04-12 | 5-ht4 receptor agonist compounds for treatment of cognitive disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT2419104T true LT2419104T (lt) | 2018-02-12 |
Family
ID=42237213
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP10713790.3T LT2419104T (lt) | 2009-04-13 | 2010-04-12 | 5-ht4 receptoriaus agonistų ir acetilcholinesterazės inhibitorių deriniai, skirti pažinimo sutrikimų gydymui |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US8404711B2 (lt) |
| EP (1) | EP2419104B1 (lt) |
| JP (1) | JP2012523437A (lt) |
| KR (1) | KR20120017421A (lt) |
| CN (2) | CN105832735A (lt) |
| AU (1) | AU2010236734B2 (lt) |
| BR (1) | BRPI1013777A8 (lt) |
| CA (1) | CA2758321A1 (lt) |
| CY (1) | CY1119800T1 (lt) |
| DK (1) | DK2419104T3 (lt) |
| ES (1) | ES2654930T3 (lt) |
| HR (1) | HRP20180018T1 (lt) |
| HU (1) | HUE038141T2 (lt) |
| IL (1) | IL215660A0 (lt) |
| LT (1) | LT2419104T (lt) |
| MX (1) | MX2011010782A (lt) |
| NO (1) | NO2419104T3 (lt) |
| PL (1) | PL2419104T3 (lt) |
| PT (1) | PT2419104T (lt) |
| RU (1) | RU2569056C2 (lt) |
| SI (1) | SI2419104T1 (lt) |
| WO (1) | WO2010120695A2 (lt) |
| ZA (1) | ZA201107490B (lt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10164139A1 (de) | 2001-12-27 | 2003-07-10 | Bayer Ag | 2-Heteroarylcarbonsäureamide |
| EP2540297B1 (en) | 2008-11-19 | 2015-04-08 | Forum Pharmaceuticals Inc. | Treatment of Cognitive Disorders with (R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof |
| RU2011150248A (ru) * | 2009-05-11 | 2013-06-20 | Энвиво Фармасьютикалз, Инк. | Лечение когнитивных расстройств с определенными рецепторами альфа-7 никотиновой кислоты в комбинации с ингибиторами ацетилхолинэстеразы |
| CN105837566B (zh) | 2010-05-17 | 2018-02-06 | 富瑞姆制药公司 | (R)‑7‑氯‑N‑(奎宁环‑3‑基)苯并[b]噻吩‑2‑甲酰胺盐酸盐单水合物的晶型 |
| EP2846796A4 (en) | 2012-05-08 | 2015-10-21 | Forum Pharmaceuticals Inc | METHODS OF MAINTAINING, PROCESSING OR ENHANCING COGNITIVE FUNCTION |
| WO2014027864A1 (ko) | 2012-08-16 | 2014-02-20 | 경희대학교 산학협력단 | 노화 및 치매의 예방 및/또는 치료 활성을 갖는 유산균 |
| US10874701B2 (en) | 2012-08-16 | 2020-12-29 | University-Industry Cooperation Group Of Kyung Hee University | Lactic acid bacteria capable of preventing and/or treating senescence and dementia |
| PL3630098T3 (pl) | 2017-05-24 | 2021-09-06 | H. Lundbeck A/S | Połączenie antagonisty receptora 5-ht6 i inhibitora acetylocholinoesterazy do zastosowania w leczeniu choroby alzheimera w subpopulacji pacjentów posiadających allele apoe4 |
| RU2019135261A (ru) | 2017-06-01 | 2021-07-09 | Эйсай Ар Энд Ди Менеджмент Ко., Лтд. | Фармацевтическая композиция, содержащая ингибитор pde9 |
| JP7282028B2 (ja) | 2017-06-02 | 2023-05-26 | 富士フイルム富山化学株式会社 | 脳萎縮予防または治療剤 |
| EA202090416A1 (ru) | 2017-07-31 | 2020-05-25 | ТЕРЕВАНС БАЙОФАРМА Ар энд Ди АйПи, ЭлЭлСи | Способы лечения симптомов гастропареза с использованием велусетрага |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1311272E (pt) * | 2000-03-03 | 2007-02-28 | Eisai R&D Man Co Ltd | Novos métodos utilizando inibidores de colinesterase |
| TWI351282B (en) * | 2004-04-07 | 2011-11-01 | Theravance Inc | Quinolinone-carboxamide compounds as 5-ht4 recepto |
| US7598265B2 (en) | 2004-09-30 | 2009-10-06 | Epix Delaware, Inc. | Compositions and methods for treating CNS disorders |
| TWI377206B (en) | 2005-04-06 | 2012-11-21 | Theravance Inc | Crystalline form of a quinolinone-carboxamide compound |
| MY147756A (en) * | 2005-05-25 | 2013-01-15 | Theravance Inc | Benzimidazole-carboxamide compounds as 5-ht4 receptor agonists |
-
2010
- 2010-04-12 US US12/758,631 patent/US8404711B2/en active Active
- 2010-04-12 EP EP10713790.3A patent/EP2419104B1/en active Active
- 2010-04-12 NO NO10713790A patent/NO2419104T3/no unknown
- 2010-04-12 PL PL10713790T patent/PL2419104T3/pl unknown
- 2010-04-12 BR BRPI1013777A patent/BRPI1013777A8/pt not_active IP Right Cessation
- 2010-04-12 CN CN201610257689.5A patent/CN105832735A/zh active Pending
- 2010-04-12 HU HUE10713790A patent/HUE038141T2/hu unknown
- 2010-04-12 DK DK10713790.3T patent/DK2419104T3/en active
- 2010-04-12 AU AU2010236734A patent/AU2010236734B2/en not_active Ceased
- 2010-04-12 LT LTEP10713790.3T patent/LT2419104T/lt unknown
- 2010-04-12 RU RU2011146032/15A patent/RU2569056C2/ru not_active IP Right Cessation
- 2010-04-12 CA CA2758321A patent/CA2758321A1/en not_active Abandoned
- 2010-04-12 MX MX2011010782A patent/MX2011010782A/es active IP Right Grant
- 2010-04-12 PT PT107137903T patent/PT2419104T/pt unknown
- 2010-04-12 ES ES10713790.3T patent/ES2654930T3/es active Active
- 2010-04-12 JP JP2012504924A patent/JP2012523437A/ja active Pending
- 2010-04-12 KR KR1020117026729A patent/KR20120017421A/ko not_active Application Discontinuation
- 2010-04-12 WO PCT/US2010/030760 patent/WO2010120695A2/en active Application Filing
- 2010-04-12 CN CN2010800164976A patent/CN102395371A/zh active Pending
- 2010-04-12 SI SI201031632T patent/SI2419104T1/en unknown
-
2011
- 2011-10-10 IL IL215660A patent/IL215660A0/en unknown
- 2011-10-12 ZA ZA2011/07490A patent/ZA201107490B/en unknown
-
2013
- 2013-02-20 US US13/771,685 patent/US20140057939A1/en not_active Abandoned
-
2018
- 2018-01-05 HR HRP20180018TT patent/HRP20180018T1/hr unknown
- 2018-01-19 CY CY20181100069T patent/CY1119800T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US8404711B2 (en) | 2013-03-26 |
| CN105832735A (zh) | 2016-08-10 |
| WO2010120695A3 (en) | 2010-12-02 |
| RU2569056C2 (ru) | 2015-11-20 |
| RU2011146032A (ru) | 2013-05-20 |
| BRPI1013777A2 (pt) | 2016-04-05 |
| AU2010236734B2 (en) | 2015-06-11 |
| US20100261752A1 (en) | 2010-10-14 |
| CY1119800T1 (el) | 2018-06-27 |
| US20140057939A1 (en) | 2014-02-27 |
| EP2419104A2 (en) | 2012-02-22 |
| AU2010236734A8 (en) | 2012-02-16 |
| CA2758321A1 (en) | 2010-10-21 |
| EP2419104B1 (en) | 2017-11-08 |
| HRP20180018T1 (hr) | 2018-02-09 |
| ES2654930T3 (es) | 2018-02-15 |
| DK2419104T3 (en) | 2018-02-05 |
| WO2010120695A2 (en) | 2010-10-21 |
| KR20120017421A (ko) | 2012-02-28 |
| SI2419104T1 (en) | 2018-03-30 |
| MX2011010782A (es) | 2012-01-20 |
| ZA201107490B (en) | 2012-06-27 |
| NO2419104T3 (lt) | 2018-04-07 |
| JP2012523437A (ja) | 2012-10-04 |
| BRPI1013777A8 (pt) | 2017-09-19 |
| PL2419104T3 (pl) | 2018-04-30 |
| AU2010236734A1 (en) | 2011-11-03 |
| PT2419104T (pt) | 2018-01-31 |
| HUE038141T2 (hu) | 2018-10-29 |
| CN102395371A (zh) | 2012-03-28 |
| IL215660A0 (en) | 2012-01-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HUE038141T2 (hu) | 5-HT4 receptor agonisták és acetilkolinészteráz inhibitorok kombinációi kognitív rendellenességek kezelésére | |
| EP2467372A4 (en) | TREATMENT OF BDNF ASSOCIATED DISEASES WITH LAQUINIMOD | |
| EP2293800A4 (en) | COMPOSITIONS AND METHODS FOR THE TREATMENT OF EARLIER DISEASES | |
| IL216140A0 (en) | Egfr inhibitors and methods of treating disorders | |
| EP2379559A4 (en) | PYRIMIDO DIAZEPINONE KINASE FERTILIZERS AND METHOD FOR THE TREATMENT OF ILLNESSES | |
| HK1199058A1 (en) | Use of toll-like receptor and agonist for treating cancer toll- | |
| ZA201001193B (en) | 2-anilinopurin-8-ones as inhibitors of TTK/MPS1 for the treatment of proliferative disorders | |
| EP2411001A4 (en) | P2X3 RECEPTOR ANTAGONISTS FOR PAIN TREATMENT | |
| EP2456868A4 (en) | METHOD AND COMPOSITIONS FOR TREATING SUFFERING OF SUFFERING THROUGH MUSCARIN RECEPTOR ACTIVATION | |
| EP2410858A4 (en) | P2X3 RECEPTOR ANTAGONISTS FOR PAIN TREATMENT | |
| EP2410857A4 (en) | ANTAGONISTS OF THE P2X3 RECEPTOR FOR THE TREATMENT OF PAIN | |
| HK1169804A1 (zh) | 治療疼痛的方法 | |
| IL216281A0 (en) | Treatment of cognitive disorders with certain alpha-7 nicotinic acid receptors in combination with acetylcholinesterase inhibitors | |
| EP2488025A4 (en) | SEPIAPTERIC INTREDUCTASE INHIBITION FOR PAIN TREATMENT | |
| HK1254745A1 (zh) | Gpr119受體調節劑和對與其相關的障礙的治療 | |
| EP2640395A4 (en) | TREATMENT OF DISEASES ASSOCIATED WITH SEARCH AND PULSE CONTROL BY PDE7 INHIBITORS | |
| EP2509596A4 (en) | COMPOUNDS AND METHOD FOR THE TREATMENT OF EYE DISEASES | |
| IL214455A0 (en) | Methods and compositions for treatment of neovascularization | |
| EP2393787A4 (en) | CADHERINE 11 INHIBITORS AND METHOD FOR THEIR USE | |
| ZA201106076B (en) | Treatment of insulin-resistant disorders | |
| EP2475390A4 (en) | METHODS AND COMPOSITIONS FOR THE TREATMENT OF TYROSINE KINASE RECEPTOR MEDIATION DISEASES OR DISORDERS | |
| EP2424885A4 (en) | COMPOSITIONS AND METHODS OF TREATING DISEASES RELATED TO EPITHELIAL CELL APOPTOSIS | |
| EP2533780A4 (en) | 5-HT4 RECEPTOR AGONISTS FOR THE TREATMENT OF DEMENTIA | |
| IL214291A0 (en) | Use of deferiprone for treatment and prevention of iron-related eye disorders | |
| ZA201202379B (en) | Antagonists of dsgs2 for treatment of cancer |