LT2419104T - 5-ht4 receptoriaus agonistų ir acetilcholinesterazės inhibitorių deriniai, skirti pažinimo sutrikimų gydymui - Google Patents
5-ht4 receptoriaus agonistų ir acetilcholinesterazės inhibitorių deriniai, skirti pažinimo sutrikimų gydymuiInfo
- Publication number
- LT2419104T LT2419104T LTEP10713790.3T LT10713790T LT2419104T LT 2419104 T LT2419104 T LT 2419104T LT 10713790 T LT10713790 T LT 10713790T LT 2419104 T LT2419104 T LT 2419104T
- Authority
- LT
- Lithuania
- Prior art keywords
- combinations
- treatment
- receptor agonists
- cognitive disorders
- acetylcholinesterase inhibitors
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16874109P | 2009-04-13 | 2009-04-13 | |
| US29255910P | 2010-01-06 | 2010-01-06 | |
| PCT/US2010/030760 WO2010120695A2 (en) | 2009-04-13 | 2010-04-12 | 5-ht4 receptor agonist compounds for treatment of cognitive disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT2419104T true LT2419104T (lt) | 2018-02-12 |
Family
ID=42237213
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP10713790.3T LT2419104T (lt) | 2009-04-13 | 2010-04-12 | 5-ht4 receptoriaus agonistų ir acetilcholinesterazės inhibitorių deriniai, skirti pažinimo sutrikimų gydymui |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US8404711B2 (lt) |
| EP (1) | EP2419104B1 (lt) |
| JP (1) | JP2012523437A (lt) |
| KR (1) | KR20120017421A (lt) |
| CN (2) | CN102395371A (lt) |
| AU (1) | AU2010236734B2 (lt) |
| BR (1) | BRPI1013777A8 (lt) |
| CA (1) | CA2758321A1 (lt) |
| CY (1) | CY1119800T1 (lt) |
| DK (1) | DK2419104T3 (lt) |
| ES (1) | ES2654930T3 (lt) |
| HR (1) | HRP20180018T1 (lt) |
| HU (1) | HUE038141T2 (lt) |
| IL (1) | IL215660A0 (lt) |
| LT (1) | LT2419104T (lt) |
| MX (1) | MX2011010782A (lt) |
| NO (1) | NO2419104T3 (lt) |
| PL (1) | PL2419104T3 (lt) |
| PT (1) | PT2419104T (lt) |
| RU (1) | RU2569056C2 (lt) |
| SI (1) | SI2419104T1 (lt) |
| WO (1) | WO2010120695A2 (lt) |
| ZA (1) | ZA201107490B (lt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10164139A1 (de) | 2001-12-27 | 2003-07-10 | Bayer Ag | 2-Heteroarylcarbonsäureamide |
| PL2889033T3 (pl) | 2008-11-19 | 2018-10-31 | Forum Pharmaceuticals Inc. | Leczenie negatywnych objawów schizofrenii za pomocą (R)-7-chloro-N-(chinuklidyn-3-ylo)benzo[b]tiofeno-2-karboksyamidu i jego farmaceutycznie dopuszczalnych soli |
| WO2010132423A1 (en) * | 2009-05-11 | 2010-11-18 | Envivo Pharmaceuticals, Inc. | Treatment of cognitive disorders with certain alpha-7 nicotinic acid receptors in combination with acetylcholinesterase inhibitors |
| MX2012013345A (es) | 2010-05-17 | 2013-02-11 | Envivo Pharmaceuticals Inc | Una forma cristalina de clorhidrato de (r)-7-cloro-n-(quinuclidin- 3-il)benzo[b]tiofeno-2-carboxamida monohidratado. |
| CA2872005A1 (en) | 2012-05-08 | 2013-11-14 | Forum Pharmaceuticals, Inc. | Methods of maintaining, treating or improving cognitive function |
| CN104781390B (zh) | 2012-08-16 | 2017-07-28 | 庆熙大学校产学协力团 | 具有对衰老及痴呆的预防和/或治疗活性的乳酸菌 |
| US10874701B2 (en) | 2012-08-16 | 2020-12-29 | University-Industry Cooperation Group Of Kyung Hee University | Lactic acid bacteria capable of preventing and/or treating senescence and dementia |
| PT3630098T (pt) | 2017-05-24 | 2021-04-21 | H Lundbeck As | Combinação de um antagonista do receptor 5-ht6 e de um inibidor de acetilcolinesterase para utilização no tratamento da doença de alzheimer numa subpopulação de pacientes portadores de alelos apoe4 |
| EP3630113A4 (en) | 2017-06-01 | 2021-02-24 | Eisai R&D Management Co., Ltd. | PHARMACEUTICAL COMPOSITION, INCLUDING PDE9 INHIBITOR |
| EP3632431A4 (en) | 2017-06-02 | 2020-06-03 | FUJIFILM Toyama Chemical Co., Ltd. | AGENTS FOR PREVENTING OR TREATING BRAIN ATROPHY |
| MX2020001217A (es) | 2017-07-31 | 2020-03-24 | Theravance Biopharma R&D Ip Llc | Metodos de tratamiento de sintomas de gastroparesia usando velusetrag. |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE345803T1 (de) * | 2000-03-03 | 2006-12-15 | Eisai Co Ltd | Neue methoden unter verwendung von cholinesteraseinhibitoren |
| TWI351282B (en) * | 2004-04-07 | 2011-11-01 | Theravance Inc | Quinolinone-carboxamide compounds as 5-ht4 recepto |
| US7598265B2 (en) | 2004-09-30 | 2009-10-06 | Epix Delaware, Inc. | Compositions and methods for treating CNS disorders |
| TWI377206B (en) * | 2005-04-06 | 2012-11-21 | Theravance Inc | Crystalline form of a quinolinone-carboxamide compound |
| MY147756A (en) * | 2005-05-25 | 2013-01-15 | Theravance Inc | Benzimidazole-carboxamide compounds as 5-ht4 receptor agonists |
-
2010
- 2010-04-12 WO PCT/US2010/030760 patent/WO2010120695A2/en active Application Filing
- 2010-04-12 RU RU2011146032/15A patent/RU2569056C2/ru not_active IP Right Cessation
- 2010-04-12 KR KR1020117026729A patent/KR20120017421A/ko not_active Application Discontinuation
- 2010-04-12 PL PL10713790T patent/PL2419104T3/pl unknown
- 2010-04-12 EP EP10713790.3A patent/EP2419104B1/en active Active
- 2010-04-12 BR BRPI1013777A patent/BRPI1013777A8/pt not_active IP Right Cessation
- 2010-04-12 MX MX2011010782A patent/MX2011010782A/es active IP Right Grant
- 2010-04-12 SI SI201031632T patent/SI2419104T1/en unknown
- 2010-04-12 CN CN2010800164976A patent/CN102395371A/zh active Pending
- 2010-04-12 US US12/758,631 patent/US8404711B2/en active Active
- 2010-04-12 DK DK10713790.3T patent/DK2419104T3/en active
- 2010-04-12 CA CA2758321A patent/CA2758321A1/en not_active Abandoned
- 2010-04-12 NO NO10713790A patent/NO2419104T3/no unknown
- 2010-04-12 HU HUE10713790A patent/HUE038141T2/hu unknown
- 2010-04-12 LT LTEP10713790.3T patent/LT2419104T/lt unknown
- 2010-04-12 PT PT107137903T patent/PT2419104T/pt unknown
- 2010-04-12 CN CN201610257689.5A patent/CN105832735A/zh active Pending
- 2010-04-12 AU AU2010236734A patent/AU2010236734B2/en not_active Ceased
- 2010-04-12 JP JP2012504924A patent/JP2012523437A/ja active Pending
- 2010-04-12 ES ES10713790.3T patent/ES2654930T3/es active Active
-
2011
- 2011-10-10 IL IL215660A patent/IL215660A0/en unknown
- 2011-10-12 ZA ZA2011/07490A patent/ZA201107490B/en unknown
-
2013
- 2013-02-20 US US13/771,685 patent/US20140057939A1/en not_active Abandoned
-
2018
- 2018-01-05 HR HRP20180018TT patent/HRP20180018T1/hr unknown
- 2018-01-19 CY CY20181100069T patent/CY1119800T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US8404711B2 (en) | 2013-03-26 |
| NO2419104T3 (lt) | 2018-04-07 |
| PT2419104T (pt) | 2018-01-31 |
| SI2419104T1 (en) | 2018-03-30 |
| BRPI1013777A8 (pt) | 2017-09-19 |
| HUE038141T2 (hu) | 2018-10-29 |
| US20140057939A1 (en) | 2014-02-27 |
| CN105832735A (zh) | 2016-08-10 |
| CN102395371A (zh) | 2012-03-28 |
| US20100261752A1 (en) | 2010-10-14 |
| CY1119800T1 (el) | 2018-06-27 |
| WO2010120695A3 (en) | 2010-12-02 |
| ZA201107490B (en) | 2012-06-27 |
| MX2011010782A (es) | 2012-01-20 |
| JP2012523437A (ja) | 2012-10-04 |
| KR20120017421A (ko) | 2012-02-28 |
| CA2758321A1 (en) | 2010-10-21 |
| DK2419104T3 (en) | 2018-02-05 |
| EP2419104A2 (en) | 2012-02-22 |
| PL2419104T3 (pl) | 2018-04-30 |
| AU2010236734A1 (en) | 2011-11-03 |
| ES2654930T3 (es) | 2018-02-15 |
| IL215660A0 (en) | 2012-01-31 |
| RU2569056C2 (ru) | 2015-11-20 |
| BRPI1013777A2 (pt) | 2016-04-05 |
| HRP20180018T1 (hr) | 2018-02-09 |
| EP2419104B1 (en) | 2017-11-08 |
| WO2010120695A2 (en) | 2010-10-21 |
| RU2011146032A (ru) | 2013-05-20 |
| AU2010236734A8 (en) | 2012-02-16 |
| AU2010236734B2 (en) | 2015-06-11 |
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