JP2012513584A5 - - Google Patents

Info

Publication number

JP2012513584A5

JP2012513584A5 JP2011541583A JP2011541583A JP2012513584A5 JP 2012513584 A5 JP2012513584 A5 JP 2012513584A5 JP 2011541583 A JP2011541583 A JP 2011541583A JP 2011541583 A JP2011541583 A JP 2011541583A JP 2012513584 A5 JP2012513584 A5 JP 2012513584A5

Authority

JP

Japan

Prior art keywords

cancer

acid sequence

patient

fragment

biomarker

Prior art date

2009-12-21

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
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• 239000000090 biomarker Substances 0.000 claims 44
• 206010028980 Neoplasm Diseases 0.000 claims 30
• 201000011510 cancer Diseases 0.000 claims 30
• 239000012634 fragment Substances 0.000 claims 22
• 238000000034 method Methods 0.000 claims 19
• 150000007523 nucleic acids Chemical group 0.000 claims 18
• 108091028043 Nucleic acid sequence Proteins 0.000 claims 16
• 239000000523 sample Substances 0.000 claims 15
• 206010005003 Bladder cancer Diseases 0.000 claims 10
• 208000007097 Urinary Bladder Neoplasms Diseases 0.000 claims 10
• 125000003275 alpha amino acid group Chemical group 0.000 claims 10
• 239000000203 mixture Substances 0.000 claims 10
• 201000005112 urinary bladder cancer Diseases 0.000 claims 10
• 206010058467 Lung neoplasm malignant Diseases 0.000 claims 9
• 201000005202 lung cancer Diseases 0.000 claims 9
• 208000020816 lung neoplasm Diseases 0.000 claims 9
• 210000001124 body fluid Anatomy 0.000 claims 8
• 239000010839 body fluid Substances 0.000 claims 8
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 6
• 150000001413 amino acids Chemical class 0.000 claims 6
• 238000001514 detection method Methods 0.000 claims 6
• 238000000338 in vitro Methods 0.000 claims 6
• 238000012544 monitoring process Methods 0.000 claims 6
• 201000010099 disease Diseases 0.000 claims 4
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
• 239000003550 marker Substances 0.000 claims 3
• 230000000295 complement effect Effects 0.000 claims 2
• 229940127089 cytotoxic agent Drugs 0.000 claims 2
• 239000002254 cytotoxic agent Substances 0.000 claims 2
• 231100000599 cytotoxic agent Toxicity 0.000 claims 2
• 239000003814 drug Substances 0.000 claims 2
• 238000003384 imaging method Methods 0.000 claims 2
• 239000003446 ligand Substances 0.000 claims 2
• 238000004519 manufacturing process Methods 0.000 claims 2
• 108020004707 nucleic acids Proteins 0.000 claims 2
• 102000039446 nucleic acids Human genes 0.000 claims 2
• 239000013610 patient sample Substances 0.000 claims 2
• 239000008194 pharmaceutical composition Substances 0.000 claims 2
• 229940022399 cancer vaccine Drugs 0.000 claims 1
• 238000009566 cancer vaccine Methods 0.000 claims 1
• 229940031724 lung cancer vaccine Drugs 0.000 claims 1
• 210000003296 saliva Anatomy 0.000 claims 1
• 210000002700 urine Anatomy 0.000 claims 1