CN102301006B - 生物标志 - Google Patents

生物标志 Download PDF

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Publication number
CN102301006B
CN102301006B CN200980155785.7A CN200980155785A CN102301006B CN 102301006 B CN102301006 B CN 102301006B CN 200980155785 A CN200980155785 A CN 200980155785A CN 102301006 B CN102301006 B CN 102301006B
Authority
CN
China
Prior art keywords
biological marker
patient
cancer
seq
purposes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN200980155785.7A
Other languages
English (en)
Chinese (zh)
Other versions
CN102301006A (zh
Inventor
R.摩根
H.S.潘达
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Surrey
Original Assignee
University of Surrey
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Surrey filed Critical University of Surrey
Publication of CN102301006A publication Critical patent/CN102301006A/zh
Application granted granted Critical
Publication of CN102301006B publication Critical patent/CN102301006B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
CN200980155785.7A 2008-12-23 2009-12-21 生物标志 Expired - Fee Related CN102301006B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0823445.2A GB0823445D0 (en) 2008-12-23 2008-12-23 Biomarker
GB0823445.2 2008-12-23
PCT/GB2009/002926 WO2010073001A1 (en) 2008-12-23 2009-12-21 Biomarker

Publications (2)

Publication Number Publication Date
CN102301006A CN102301006A (zh) 2011-12-28
CN102301006B true CN102301006B (zh) 2015-07-15

Family

ID=40344114

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200980155785.7A Expired - Fee Related CN102301006B (zh) 2008-12-23 2009-12-21 生物标志

Country Status (15)

Country Link
US (1) US9624548B2 (enExample)
EP (1) EP2382327B1 (enExample)
JP (1) JP5947040B2 (enExample)
CN (1) CN102301006B (enExample)
AU (1) AU2009332712B2 (enExample)
BR (1) BRPI0923525A2 (enExample)
CA (1) CA2747760C (enExample)
ES (1) ES2725150T3 (enExample)
GB (1) GB0823445D0 (enExample)
IL (1) IL213510A (enExample)
MX (1) MX343251B (enExample)
NZ (1) NZ593392A (enExample)
RU (1) RU2573925C2 (enExample)
WO (1) WO2010073001A1 (enExample)
ZA (1) ZA201105184B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2472856B (en) 2009-08-21 2012-07-11 Cantargia Ab IL1-RAP modulators and uses thereof
ES2714716T3 (es) 2011-01-19 2019-05-29 Cantargia Ab Anticuerpos anti-IL1RAP y su uso para el tratamiento de tumores sólidos
US11371941B2 (en) * 2016-07-04 2022-06-28 Celltool Gmbh Device and method for the determination of transfection
KR101777085B1 (ko) * 2017-02-23 2017-09-11 주식회사 성균바이오텍 En2 단백질의 면역원성 단편 펩타이드 또는 이를 특이적으로 인식하는 항체 조성물
KR101923199B1 (ko) 2018-04-25 2018-11-28 주식회사 무진메디 펩스타틴 a를 함유하는 소변 내 en2 진단용 조성물
EP4043583A4 (en) 2019-10-02 2023-11-08 Kyushu University, National University Corporation Biomarker, method, kit and array for predicting therapeutic effects of bcg intravesical infusion therapy in treating bladder cancer

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008075056A1 (en) * 2006-12-19 2008-06-26 The University Of Surrey Cancer biomarkers

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2469089A1 (en) 2003-07-08 2005-01-08 Institut De Recherches Cliniques De Montreal En-2 gene, disgnostic and therapeutic uses thereof
EP2011885B1 (en) * 2005-02-10 2015-04-22 Oncotherapy Science, Inc. Method of diagnosing bladder cancer
SI2258871T1 (sl) * 2007-01-19 2014-09-30 Epigenomics Ag Intellectual Property Postopki in nukleinske kisline za analize celičnih proliferativnih motenj
AU2008334901A1 (en) 2007-12-11 2009-06-18 Epigenomics Ag Methods and nucleic acids for analyses of lung carcinoma

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008075056A1 (en) * 2006-12-19 2008-06-26 The University Of Surrey Cancer biomarkers

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
EN2 is a candidate oncogene in human breast cancer;Nicole L Martin;《Oncogene》;20050620;第24卷;6890–6901 *
Homeobox gene methylation in lung cancer studied by genome-wide analysis with a microarray-based methylated CpG island recovery assay;Tibor Rauch;《PNAS》;20070331;第104卷(第13期);5527–5532 *

Also Published As

Publication number Publication date
JP5947040B2 (ja) 2016-07-06
AU2009332712B2 (en) 2015-05-28
US9624548B2 (en) 2017-04-18
RU2011130795A (ru) 2013-01-27
WO2010073001A1 (en) 2010-07-01
MX343251B (es) 2016-10-31
NZ593392A (en) 2013-05-31
CA2747760C (en) 2020-01-21
JP2012513584A (ja) 2012-06-14
IL213510A (en) 2016-04-21
CN102301006A (zh) 2011-12-28
EP2382327B1 (en) 2019-02-13
RU2573925C2 (ru) 2016-01-27
ZA201105184B (en) 2012-02-29
EP2382327A1 (en) 2011-11-02
AU2009332712A1 (en) 2011-07-07
MX2011006773A (es) 2011-08-03
GB0823445D0 (en) 2009-01-28
CA2747760A1 (en) 2010-07-01
BRPI0923525A2 (pt) 2020-08-11
US20120020888A1 (en) 2012-01-26
IL213510A0 (en) 2011-07-31
ES2725150T3 (es) 2019-09-19

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Legal Events

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C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20150715