JP2010528261A5 - - Google Patents
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- Publication number
- JP2010528261A5 JP2010528261A5 JP2010507474A JP2010507474A JP2010528261A5 JP 2010528261 A5 JP2010528261 A5 JP 2010528261A5 JP 2010507474 A JP2010507474 A JP 2010507474A JP 2010507474 A JP2010507474 A JP 2010507474A JP 2010528261 A5 JP2010528261 A5 JP 2010528261A5
- Authority
- JP
- Japan
- Prior art keywords
- gpr110
- antibody
- level
- sample
- epitope
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 101000718228 Homo sapiens Adhesion G-protein coupled receptor F1 Proteins 0.000 claims 43
- 102100026443 Adhesion G-protein coupled receptor F1 Human genes 0.000 claims 39
- 238000000034 method Methods 0.000 claims 22
- 206010060862 Prostate cancer Diseases 0.000 claims 15
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 15
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 12
- 201000005202 lung cancer Diseases 0.000 claims 12
- 208000020816 lung neoplasm Diseases 0.000 claims 12
- 210000002307 prostate Anatomy 0.000 claims 12
- 210000004072 lung Anatomy 0.000 claims 10
- 210000004369 blood Anatomy 0.000 claims 7
- 239000008280 blood Substances 0.000 claims 7
- 210000002966 serum Anatomy 0.000 claims 7
- 108010072866 Prostate-Specific Antigen Proteins 0.000 claims 6
- 102000007066 Prostate-Specific Antigen Human genes 0.000 claims 6
- 238000001514 detection method Methods 0.000 claims 6
- 210000001124 body fluid Anatomy 0.000 claims 5
- 239000010839 body fluid Substances 0.000 claims 4
- 239000012634 fragment Substances 0.000 claims 4
- 102000055600 human ADGRF1 Human genes 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 238000012216 screening Methods 0.000 claims 4
- 210000001519 tissue Anatomy 0.000 claims 4
- 239000003550 marker Substances 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 102000010956 Glypican Human genes 0.000 claims 2
- 108050001154 Glypican Proteins 0.000 claims 2
- 102100032530 Glypican-3 Human genes 0.000 claims 2
- 108050007237 Glypican-3 Proteins 0.000 claims 2
- 125000000539 amino acid group Chemical group 0.000 claims 2
- 238000003556 assay Methods 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 238000003018 immunoassay Methods 0.000 claims 2
- 238000005259 measurement Methods 0.000 claims 2
- 239000007790 solid phase Substances 0.000 claims 2
- 229940124597 therapeutic agent Drugs 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 102000023732 binding proteins Human genes 0.000 claims 1
- 108091008324 binding proteins Proteins 0.000 claims 1
- 239000000090 biomarker Substances 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 230000003013 cytotoxicity Effects 0.000 claims 1
- 231100000135 cytotoxicity Toxicity 0.000 claims 1
- 230000003247 decreasing effect Effects 0.000 claims 1
- 230000001419 dependent effect Effects 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 230000035899 viability Effects 0.000 claims 1
- 230000000007 visual effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91671907P | 2007-05-08 | 2007-05-08 | |
| PCT/US2008/005983 WO2008140774A2 (en) | 2007-05-08 | 2008-05-08 | Methods for diagnosing and treating prostate and lung cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010528261A JP2010528261A (ja) | 2010-08-19 |
| JP2010528261A5 true JP2010528261A5 (enExample) | 2011-08-25 |
Family
ID=40002842
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010507474A Pending JP2010528261A (ja) | 2007-05-08 | 2008-05-08 | 前立腺癌および肺癌の診断および治療方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20130224209A1 (enExample) |
| EP (1) | EP2156184B1 (enExample) |
| JP (1) | JP2010528261A (enExample) |
| CN (1) | CN101918836B (enExample) |
| AU (1) | AU2008251877A1 (enExample) |
| CA (1) | CA2686954A1 (enExample) |
| WO (1) | WO2008140774A2 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5305361B2 (ja) | 2007-05-04 | 2013-10-02 | オプコ・ダイアグノスティクス・リミテッド・ライアビリティ・カンパニー | 流体コネクタおよびマイクロ流体システム |
| US10236078B2 (en) | 2008-11-17 | 2019-03-19 | Veracyte, Inc. | Methods for processing or analyzing a sample of thyroid tissue |
| US8669057B2 (en) | 2009-05-07 | 2014-03-11 | Veracyte, Inc. | Methods and compositions for diagnosis of thyroid conditions |
| US20130209476A1 (en) * | 2010-06-04 | 2013-08-15 | The Brigham And Women's Hospital Inc. | Treatment of inflammatory disorders |
| JP5909070B2 (ja) * | 2010-10-28 | 2016-04-26 | 国立大学法人 東京大学 | Ｇｓ共役受容体に対する医薬品候補化合物をスクリーニングする方法 |
| KR101933752B1 (ko) | 2012-03-05 | 2018-12-28 | 오와이 아크틱 파트너스 에이비 | 전립선 암의 위험성 및 전립선 부피를 예측하는 방법 및 장치 |
| CN102914658A (zh) * | 2012-10-24 | 2013-02-06 | 高维强 | Crisp3蛋白在前列腺癌诊断和治疗中的应用 |
| US11976329B2 (en) | 2013-03-15 | 2024-05-07 | Veracyte, Inc. | Methods and systems for detecting usual interstitial pneumonia |
| WO2015106311A1 (en) | 2014-01-17 | 2015-07-23 | Minomic International Ltd. | Cell surface prostate cancer antigen for diagnosis |
| CN104090103B (zh) * | 2014-03-24 | 2016-08-31 | 福州市传染病医院 | 基于抗体修饰ZnSe纳米晶检测肝癌标志物GPC3的试剂盒 |
| ES2964706T3 (es) | 2014-03-28 | 2024-04-09 | Opko Diagnostics Llc | Composiciones y métodos relacionados con el diagnóstico de cáncer de próstata |
| US12326453B2 (en) | 2014-03-28 | 2025-06-10 | Opko Diagnostics, Llc | Compositions and methods for active surveillance of prostate cancer |
| EP2944652A1 (en) * | 2014-05-13 | 2015-11-18 | Technische Universität München | Glypican-3-specific T-cell receptors and their uses for immunotherapy of hepatocellular carcinoma |
| JP6775499B2 (ja) * | 2014-07-14 | 2020-10-28 | ベラサイト インコーポレイテッド | 肺がん状態の評価方法 |
| US12297505B2 (en) | 2014-07-14 | 2025-05-13 | Veracyte, Inc. | Algorithms for disease diagnostics |
| JP7356788B2 (ja) | 2014-11-05 | 2023-10-05 | ベラサイト インコーポレイテッド | 機械学習および高次元転写データを使用して経気管支生検における特発性肺線維症を診断するシステムおよび方法 |
| US11097005B2 (en) | 2014-12-15 | 2021-08-24 | The Brigham And Women's Hospital, Inc. | Use of cadherin-11 antagonists to treat metabolic disorders and/or increase insulin sensitivity |
| HUE055020T2 (hu) | 2015-03-27 | 2021-11-29 | Opko Diagnostics Llc | Prosztata-antigén szabványok és azok felhasználása |
| CN112034185A (zh) * | 2020-09-11 | 2020-12-04 | 上海市胸科医院 | Gpr110、vegfr、cd34在鉴别肺腺癌亚型中的用途 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2795403B2 (ja) * | 1986-07-30 | 1998-09-10 | 株式会社 シノテスト | 免疫的測定方法及び装置 |
| IL141061A0 (en) * | 1998-08-10 | 2002-02-10 | Urogenesys Inc | Bpc-1 a secreted brain specific protein expressed and sectreted by prostate and bladder cancer cells |
| WO2002077233A2 (en) * | 2000-11-08 | 2002-10-03 | Millennium Pharmaceuticals, Inc. | 38650, 28472, 5495, 65507, 81588 and 14354 METHODS AND COMPOSITIONS OF HUMAN PROTEINS AND USES THEREOF |
| EP1463928A2 (en) | 2001-04-18 | 2004-10-06 | Protein Design Labs | Methods of diagnosis of lung cancer, compositions and methods of screening for modulators of lung cancer |
| AU2002337657A1 (en) * | 2001-07-25 | 2003-02-17 | Millennium Pharmaceuticals, Inc. | Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of prostate cancer |
| WO2004023145A1 (ja) * | 2002-09-04 | 2004-03-18 | Perseus Proteomics Inc. | Ｇｐｃ3の検出による癌の診断方法 |
| US20070010726A1 (en) * | 2002-10-02 | 2007-01-11 | Alfred E. Mann Inst. For Biomedical Engineering At The University Of Southern California | Internal biochemical sensing device |
| JP2004279157A (ja) * | 2003-03-14 | 2004-10-07 | Rohto Pharmaceut Co Ltd | 癌病巣判定のためのキット並びに方法 |
| US20060094046A1 (en) * | 2004-02-11 | 2006-05-04 | Arie Abo | Compositions and methods relating to angiogenesis and tumorigenesis |
| US20070254317A1 (en) * | 2004-03-03 | 2007-11-01 | Biomerieux | Method for Detecting the Activatable Free Form of Psa and the Use Thereof for Diagnosing Benign Pathologies of the Prostate and Adenocarcinoma of the Prostate |
| EP1831684A4 (en) * | 2004-11-30 | 2009-03-11 | Veridex Llc | LUNGENKREBSPROGNOSTIK |
| US20060211059A1 (en) * | 2005-03-18 | 2006-09-21 | Taneja Samir S | Methods of improving screening, diagnosis and staging of prostate cancer using serum testosterone |
| JP2007075072A (ja) * | 2005-09-16 | 2007-03-29 | Satoshi Takahashi | プロサイモシンαの機能抑制用組成物を含む抗癌剤、およびプロサイモシンα遺伝子の発現抑制用組成物に含有される核酸 |
| WO2007047796A2 (en) | 2005-10-17 | 2007-04-26 | Institute For Systems Biology | Tissue-and serum-derived glycoproteins and methods of their use |
-
2008
- 2008-05-08 CN CN200880023852.5A patent/CN101918836B/zh not_active Expired - Fee Related
- 2008-05-08 CA CA 2686954 patent/CA2686954A1/en not_active Abandoned
- 2008-05-08 WO PCT/US2008/005983 patent/WO2008140774A2/en not_active Ceased
- 2008-05-08 JP JP2010507474A patent/JP2010528261A/ja active Pending
- 2008-05-08 AU AU2008251877A patent/AU2008251877A1/en not_active Abandoned
- 2008-05-08 EP EP20080754314 patent/EP2156184B1/en not_active Not-in-force
-
2013
- 2013-01-21 US US13/746,180 patent/US20130224209A1/en not_active Abandoned
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