CA2686954A1 - Methods for diagnosing and treating prostate and lung cancer - Google Patents

Methods for diagnosing and treating prostate and lung cancer Download PDF

Info

Publication number
CA2686954A1
CA2686954A1 CA 2686954 CA2686954A CA2686954A1 CA 2686954 A1 CA2686954 A1 CA 2686954A1 CA 2686954 CA2686954 CA 2686954 CA 2686954 A CA2686954 A CA 2686954A CA 2686954 A1 CA2686954 A1 CA 2686954A1
Authority
CA
Canada
Prior art keywords
gpr110
antibody
prostate
sample
level
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2686954
Other languages
English (en)
French (fr)
Inventor
Bruce Wang
Matthias Wabl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Picobella LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2686954A1 publication Critical patent/CA2686954A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • G01N33/5752
    • G01N33/57555
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA 2686954 2007-05-08 2008-05-08 Methods for diagnosing and treating prostate and lung cancer Abandoned CA2686954A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US91671907P 2007-05-08 2007-05-08
US60/916,719 2007-05-08
PCT/US2008/005983 WO2008140774A2 (en) 2007-05-08 2008-05-08 Methods for diagnosing and treating prostate and lung cancer

Publications (1)

Publication Number Publication Date
CA2686954A1 true CA2686954A1 (en) 2008-11-20

Family

ID=40002842

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2686954 Abandoned CA2686954A1 (en) 2007-05-08 2008-05-08 Methods for diagnosing and treating prostate and lung cancer

Country Status (7)

Country Link
US (1) US20130224209A1 (enExample)
EP (1) EP2156184B1 (enExample)
JP (1) JP2010528261A (enExample)
CN (1) CN101918836B (enExample)
AU (1) AU2008251877A1 (enExample)
CA (1) CA2686954A1 (enExample)
WO (1) WO2008140774A2 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008137008A2 (en) 2007-05-04 2008-11-13 Claros Diagnostics, Inc. Fluidic connectors and microfluidic systems
US10236078B2 (en) 2008-11-17 2019-03-19 Veracyte, Inc. Methods for processing or analyzing a sample of thyroid tissue
US8669057B2 (en) 2009-05-07 2014-03-11 Veracyte, Inc. Methods and compositions for diagnosis of thyroid conditions
WO2011153397A2 (en) * 2010-06-04 2011-12-08 The Brigham And Women's Hospital, Inc. Treatment of inflammatory disorders
JP5909070B2 (ja) * 2010-10-28 2016-04-26 国立大学法人 東京大学 Gs共役受容体に対する医薬品候補化合物をスクリーニングする方法
PL3312749T3 (pl) 2012-03-05 2024-10-07 Oy Arctic Partners Ab Metody i aparaty do prognozowania ryzyka raka gruczołu krokowego i objętości gruczołu krokowego
CN102914658A (zh) * 2012-10-24 2013-02-06 高维强 Crisp3蛋白在前列腺癌诊断和治疗中的应用
US11976329B2 (en) 2013-03-15 2024-05-07 Veracyte, Inc. Methods and systems for detecting usual interstitial pneumonia
EP3094976B1 (en) 2014-01-17 2020-03-25 Minomic International Ltd. Cell surface prostate cancer antigen for diagnosis
CN104090103B (zh) * 2014-03-24 2016-08-31 福州市传染病医院 基于抗体修饰ZnSe纳米晶检测肝癌标志物GPC3的试剂盒
US12326453B2 (en) 2014-03-28 2025-06-10 Opko Diagnostics, Llc Compositions and methods for active surveillance of prostate cancer
PE20170298A1 (es) * 2014-03-28 2017-04-18 Opko Diagnostics Llc Composiciones y metodos relacionados con el diagnostico del cancer de prostata
EP2944652A1 (en) * 2014-05-13 2015-11-18 Technische Universität München Glypican-3-specific T-cell receptors and their uses for immunotherapy of hepatocellular carcinoma
US12297505B2 (en) 2014-07-14 2025-05-13 Veracyte, Inc. Algorithms for disease diagnostics
JP6775499B2 (ja) * 2014-07-14 2020-10-28 ベラサイト インコーポレイテッド 肺がん状態の評価方法
US20170335396A1 (en) 2014-11-05 2017-11-23 Veracyte, Inc. Systems and methods of diagnosing idiopathic pulmonary fibrosis on transbronchial biopsies using machine learning and high dimensional transcriptional data
WO2016100301A1 (en) 2014-12-15 2016-06-23 The Brigham And Women's Hospital, Inc. Use of cadherin-11 antagonists to treat obesity-associated conditions and other metabolic disorders
JP6749337B2 (ja) 2015-03-27 2020-09-02 オプコ・ダイアグノスティクス・リミテッド・ライアビリティ・カンパニーOpko Diagnostics,Llc 前立腺抗原標準およびその使用
CN112034185A (zh) * 2020-09-11 2020-12-04 上海市胸科医院 Gpr110、vegfr、cd34在鉴别肺腺癌亚型中的用途
KR102730255B1 (ko) * 2022-08-12 2024-11-15 (주)맥시온 암 진단용 다중 바이오마커 및 이의 용도

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2795403B2 (ja) * 1986-07-30 1998-09-10 株式会社 シノテスト 免疫的測定方法及び装置
EP1104462B1 (en) * 1998-08-10 2007-01-03 Agensys, Inc. Bpc-1: a secreted brain specific protein expressed and secreted by prostate and bladder cancer cells
EP1364012A2 (en) 2000-11-08 2003-11-26 Millennium Pharmaceuticals, Inc. 38650, 28472, 5495, 65507, 81588 and 14354 methods and compositions of human proteins and uses thereof
EP1463928A2 (en) * 2001-04-18 2004-10-06 Protein Design Labs Methods of diagnosis of lung cancer, compositions and methods of screening for modulators of lung cancer
WO2003009814A2 (en) * 2001-07-25 2003-02-06 Millennium Pharmaceuticals, Inc. Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of prostate cancer
WO2004023145A1 (ja) * 2002-09-04 2004-03-18 Perseus Proteomics Inc. Gpc3の検出による癌の診断方法
US20070010726A1 (en) * 2002-10-02 2007-01-11 Alfred E. Mann Inst. For Biomedical Engineering At The University Of Southern California Internal biochemical sensing device
JP2004279157A (ja) * 2003-03-14 2004-10-07 Rohto Pharmaceut Co Ltd 癌病巣判定のためのキット並びに方法
US20060094046A1 (en) * 2004-02-11 2006-05-04 Arie Abo Compositions and methods relating to angiogenesis and tumorigenesis
CN1926433A (zh) * 2004-03-03 2007-03-07 拜奥默里克斯公司 用于检测psa的可活化游离形式的方法及其用于诊断前列腺的良性病理学和前列腺的腺癌的用途
CA2589782A1 (en) * 2004-11-30 2006-06-08 Veridex Llc Lung cancer prognostics
US20060211059A1 (en) * 2005-03-18 2006-09-21 Taneja Samir S Methods of improving screening, diagnosis and staging of prostate cancer using serum testosterone
JP2007075072A (ja) * 2005-09-16 2007-03-29 Satoshi Takahashi プロサイモシンαの機能抑制用組成物を含む抗癌剤、およびプロサイモシンα遺伝子の発現抑制用組成物に含有される核酸
EP1938104A2 (en) * 2005-10-17 2008-07-02 Institute for Systems Biology Tissue-and serum-derived glycoproteins and methods of their use

Also Published As

Publication number Publication date
CN101918836A (zh) 2010-12-15
US20130224209A1 (en) 2013-08-29
EP2156184B1 (en) 2013-11-27
EP2156184A4 (en) 2010-07-21
WO2008140774A9 (en) 2010-02-11
EP2156184A2 (en) 2010-02-24
AU2008251877A1 (en) 2008-11-20
JP2010528261A (ja) 2010-08-19
WO2008140774A3 (en) 2009-01-15
AU2008251877A2 (en) 2010-02-04
WO2008140774A2 (en) 2008-11-20
AU2008251877A9 (en) 2010-01-21
CN101918836B (zh) 2014-04-30

Similar Documents

Publication Publication Date Title
US20130224209A1 (en) Methods for diagnosing and treating prostate and lung cancer
US8071324B2 (en) Methods for diagnosing and treating kidney cancer
US20100041126A1 (en) Methods for diagnosing and treating prostate cancer
US20090258358A1 (en) Methods for Diagnosing and Treating Kidney and Colorectal Cancer
AU2011250588C1 (en) Method for the diagnosis of epithelial cancers by the detection of EpICD polypeptide
KR100819395B1 (ko) 포유류에서의 전-종양 및/또는 종양 상태의 확인법
US9625461B2 (en) Method of detecting cancer using delta-catenin
CA2662012C (en) Boris isoforms and methods of detecting and treating disease
US7910316B2 (en) Kit and method for detecting urothelial cancer
WO2003097872A2 (en) G - protein coupled receptor marker molecules associated with colorectal lesions
JP2009168669A (ja) 胃癌の診断又は検出のための組成物及び方法
US7785814B2 (en) Method of detecting cancer based on immune reaction to BORIS
WO2002016939A2 (en) Methods of diagnosis of cancer and screening for cancer modulators
JP2009195243A (ja) Tbx21の変更された発現に関連する癌における新規組成物および方法
KR101219979B1 (ko) 갑상선 유두암종의 림프절 전이 진단 방법
JP3524536B2 (ja) 癌の診断、モニタリング、ステージング、イメージングおよび処置のための新規方法
US6379893B1 (en) Evaluation of adenocarcinoma of the prostate and breast using anti-dystroglycan antibodies
US20030087245A1 (en) Uses of PBH1 in the diagnosis and therapeutic treatment of prostate cancer
US8313917B2 (en) Methods of diagnosing latent and active malignancies
JP2008263840A (ja) 胃ガンの診断又は検出のための組成物及び方法

Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20140508

FZDE Discontinued

Effective date: 20140508