JP2010528261A - 前立腺癌および肺癌の診断および治療方法 - Google Patents

前立腺癌および肺癌の診断および治療方法 Download PDF

Info

Publication number
JP2010528261A
JP2010528261A JP2010507474A JP2010507474A JP2010528261A JP 2010528261 A JP2010528261 A JP 2010528261A JP 2010507474 A JP2010507474 A JP 2010507474A JP 2010507474 A JP2010507474 A JP 2010507474A JP 2010528261 A JP2010528261 A JP 2010528261A
Authority
JP
Japan
Prior art keywords
gpr110
antibody
level
subject
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010507474A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010528261A5 (enExample
Inventor
ブルース・ワン
マティアス・ウォブル
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Picobella LLC
Original Assignee
Picobella LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Picobella LLC filed Critical Picobella LLC
Publication of JP2010528261A publication Critical patent/JP2010528261A/ja
Publication of JP2010528261A5 publication Critical patent/JP2010528261A5/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57423Specifically defined cancers of lung
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57434Specifically defined cancers of prostate
    • G01N33/5752
    • G01N33/57555
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2010507474A 2007-05-08 2008-05-08 前立腺癌および肺癌の診断および治療方法 Pending JP2010528261A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91671907P 2007-05-08 2007-05-08
PCT/US2008/005983 WO2008140774A2 (en) 2007-05-08 2008-05-08 Methods for diagnosing and treating prostate and lung cancer

Publications (2)

Publication Number Publication Date
JP2010528261A true JP2010528261A (ja) 2010-08-19
JP2010528261A5 JP2010528261A5 (enExample) 2011-08-25

Family

ID=40002842

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010507474A Pending JP2010528261A (ja) 2007-05-08 2008-05-08 前立腺癌および肺癌の診断および治療方法

Country Status (7)

Country Link
US (1) US20130224209A1 (enExample)
EP (1) EP2156184B1 (enExample)
JP (1) JP2010528261A (enExample)
CN (1) CN101918836B (enExample)
AU (1) AU2008251877A1 (enExample)
CA (1) CA2686954A1 (enExample)
WO (1) WO2008140774A2 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012105640A (ja) * 2010-10-28 2012-06-07 Univ Of Tokyo Gs共役受容体に対する医薬品候補化合物をスクリーニングする方法
JP2015512050A (ja) * 2012-03-05 2015-04-23 オサケユキテュア・アークティック・パートナーズ・アクチボラゲットOy Arctic Partnersab 前立腺癌のリスク及び前立腺容積を予測する方法及び装置
JP2025526815A (ja) * 2022-08-12 2025-08-15 マキシオン コーポレーション 癌診断用多重バイオマーカー及びその用途

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101754812B (zh) 2007-05-04 2013-06-26 克拉洛诊断仪器公司 流体连接器和微流体系统
US10236078B2 (en) 2008-11-17 2019-03-19 Veracyte, Inc. Methods for processing or analyzing a sample of thyroid tissue
US8669057B2 (en) 2009-05-07 2014-03-11 Veracyte, Inc. Methods and compositions for diagnosis of thyroid conditions
JP2013528622A (ja) * 2010-06-04 2013-07-11 ザ・ブリガーム・アンド・ウーメンズ・ホスピタル・インコーポレーテッド 炎症性障害の処置
CN102914658A (zh) * 2012-10-24 2013-02-06 高维强 Crisp3蛋白在前列腺癌诊断和治疗中的应用
US11976329B2 (en) 2013-03-15 2024-05-07 Veracyte, Inc. Methods and systems for detecting usual interstitial pneumonia
EP3094976B1 (en) 2014-01-17 2020-03-25 Minomic International Ltd. Cell surface prostate cancer antigen for diagnosis
CN104090103B (zh) * 2014-03-24 2016-08-31 福州市传染病医院 基于抗体修饰ZnSe纳米晶检测肝癌标志物GPC3的试剂盒
US12326453B2 (en) 2014-03-28 2025-06-10 Opko Diagnostics, Llc Compositions and methods for active surveillance of prostate cancer
WO2015148979A1 (en) * 2014-03-28 2015-10-01 Opko Diagnostics, Llc Compositons and methods related to diagnosis of prostate cancer
EP2944652A1 (en) * 2014-05-13 2015-11-18 Technische Universität München Glypican-3-specific T-cell receptors and their uses for immunotherapy of hepatocellular carcinoma
CN114807368A (zh) 2014-07-14 2022-07-29 威拉赛特公司 用于评估肺癌状态的方法
US12297505B2 (en) 2014-07-14 2025-05-13 Veracyte, Inc. Algorithms for disease diagnostics
WO2016073768A1 (en) 2014-11-05 2016-05-12 Veracyte, Inc. Systems and methods of diagnosing idiopathic pulmonary fibrosis on transbronchial biopsies using machine learning and high dimensional transcriptional data
US11097005B2 (en) 2014-12-15 2021-08-24 The Brigham And Women's Hospital, Inc. Use of cadherin-11 antagonists to treat metabolic disorders and/or increase insulin sensitivity
JP6749337B2 (ja) 2015-03-27 2020-09-02 オプコ・ダイアグノスティクス・リミテッド・ライアビリティ・カンパニーOpko Diagnostics,Llc 前立腺抗原標準およびその使用
CN112034185A (zh) * 2020-09-11 2020-12-04 上海市胸科医院 Gpr110、vegfr、cd34在鉴别肺腺癌亚型中的用途

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08101198A (ja) * 1986-07-30 1996-04-16 Shinotesuto:Kk 免疫的測定方法及び装置
US20030108963A1 (en) * 2001-07-25 2003-06-12 Millennium Pharmaceuticals, Inc. Novel genes, compositions, kit, and methods for identification, assessment, prevention and therapy of prostate cancer
WO2004038420A1 (ja) * 2002-09-04 2004-05-06 Perseus Proteomics Inc. Gpc3の検出による癌の診断方法
JP2004279157A (ja) * 2003-03-14 2004-10-07 Rohto Pharmaceut Co Ltd 癌病巣判定のためのキット並びに方法
WO2005085292A2 (fr) * 2004-03-03 2005-09-15 Biomerieux Procede de detection de la forme libre activable du psa et son utilisation pour le diagnostic des pathologies benignes de la prostate et de l'adenocarcinome de la prostate
WO2006060653A2 (en) * 2004-11-30 2006-06-08 Veridex Llc Lung cancer prognostics
JP2006320324A (ja) * 1998-08-10 2006-11-30 Agensys Inc Bpc−1:前立腺および膀胱の癌細胞によって発現および分泌がなされる分泌型の脳特異的蛋白質
JP2007075072A (ja) * 2005-09-16 2007-03-29 Satoshi Takahashi プロサイモシンαの機能抑制用組成物を含む抗癌剤、およびプロサイモシンα遺伝子の発現抑制用組成物に含有される核酸

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001297556A1 (en) * 2000-11-08 2002-10-03 Millennium Pharmaceuticals, Inc. 38650, 28472, 5495, 65507, 81588 and 14354 methods and compositions of human proteins and uses thereof
JP2005527180A (ja) * 2001-04-18 2005-09-15 プロテイン デザイン ラブス, インコーポレイテッド 肺がんの診断方法、肺がんの修飾因子の組成及びスクリーニングの方法
WO2006086578A1 (en) * 2002-10-02 2006-08-17 Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California Internal biochemical sensing device
US20060094046A1 (en) * 2004-02-11 2006-05-04 Arie Abo Compositions and methods relating to angiogenesis and tumorigenesis
US20060211059A1 (en) * 2005-03-18 2006-09-21 Taneja Samir S Methods of improving screening, diagnosis and staging of prostate cancer using serum testosterone
WO2007047796A2 (en) * 2005-10-17 2007-04-26 Institute For Systems Biology Tissue-and serum-derived glycoproteins and methods of their use

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08101198A (ja) * 1986-07-30 1996-04-16 Shinotesuto:Kk 免疫的測定方法及び装置
JP2006320324A (ja) * 1998-08-10 2006-11-30 Agensys Inc Bpc−1:前立腺および膀胱の癌細胞によって発現および分泌がなされる分泌型の脳特異的蛋白質
US20030108963A1 (en) * 2001-07-25 2003-06-12 Millennium Pharmaceuticals, Inc. Novel genes, compositions, kit, and methods for identification, assessment, prevention and therapy of prostate cancer
WO2004038420A1 (ja) * 2002-09-04 2004-05-06 Perseus Proteomics Inc. Gpc3の検出による癌の診断方法
JP2004279157A (ja) * 2003-03-14 2004-10-07 Rohto Pharmaceut Co Ltd 癌病巣判定のためのキット並びに方法
WO2005085292A2 (fr) * 2004-03-03 2005-09-15 Biomerieux Procede de detection de la forme libre activable du psa et son utilisation pour le diagnostic des pathologies benignes de la prostate et de l'adenocarcinome de la prostate
WO2006060653A2 (en) * 2004-11-30 2006-06-08 Veridex Llc Lung cancer prognostics
JP2007075072A (ja) * 2005-09-16 2007-03-29 Satoshi Takahashi プロサイモシンαの機能抑制用組成物を含む抗癌剤、およびプロサイモシンα遺伝子の発現抑制用組成物に含有される核酸

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012105640A (ja) * 2010-10-28 2012-06-07 Univ Of Tokyo Gs共役受容体に対する医薬品候補化合物をスクリーニングする方法
JP2015512050A (ja) * 2012-03-05 2015-04-23 オサケユキテュア・アークティック・パートナーズ・アクチボラゲットOy Arctic Partnersab 前立腺癌のリスク及び前立腺容積を予測する方法及び装置
JP2025526815A (ja) * 2022-08-12 2025-08-15 マキシオン コーポレーション 癌診断用多重バイオマーカー及びその用途

Also Published As

Publication number Publication date
AU2008251877A1 (en) 2008-11-20
WO2008140774A9 (en) 2010-02-11
US20130224209A1 (en) 2013-08-29
CN101918836A (zh) 2010-12-15
EP2156184A4 (en) 2010-07-21
CA2686954A1 (en) 2008-11-20
EP2156184B1 (en) 2013-11-27
WO2008140774A2 (en) 2008-11-20
EP2156184A2 (en) 2010-02-24
AU2008251877A2 (en) 2010-02-04
CN101918836B (zh) 2014-04-30
AU2008251877A9 (en) 2010-01-21
WO2008140774A3 (en) 2009-01-15

Similar Documents

Publication Publication Date Title
CN101918836B (zh) 诊断和治疗前列腺癌和肺癌的方法
JP3844366B2 (ja) 前立腺ガンの免疫診断のための化合物およびそれらの使用方法
US8071324B2 (en) Methods for diagnosing and treating kidney cancer
US20100041126A1 (en) Methods for diagnosing and treating prostate cancer
US20090258358A1 (en) Methods for Diagnosing and Treating Kidney and Colorectal Cancer
AU2011250588C1 (en) Method for the diagnosis of epithelial cancers by the detection of EpICD polypeptide
JP2010508855A (ja) 前立腺癌マーカーとしてのspink1およびその使用
JP2012103264A (ja) 癌診断用抗体
AU2007271232A1 (en) Prostate specific transcripts and the use thereof for prostate cancer therapeutics and diagnostics
KR100819395B1 (ko) 포유류에서의 전-종양 및/또는 종양 상태의 확인법
US9625461B2 (en) Method of detecting cancer using delta-catenin
US7910316B2 (en) Kit and method for detecting urothelial cancer
JP2004532390A (ja) 前立腺癌のマーカとしてのpin1
WO2008028066A2 (en) Boris isoforms and methods of detecting and treating disease
WO2003097872A2 (en) G - protein coupled receptor marker molecules associated with colorectal lesions
KR101219979B1 (ko) 갑상선 유두암종의 림프절 전이 진단 방법
JP2004511758A (ja) 大腸癌の診断、モニタリング、ステージング、イメージングおよび処置の方法
JP2008263840A (ja) 胃ガンの診断又は検出のための組成物及び方法
JP2005527196A (ja) アンドロゲン調節性核酸分子およびコード化タンパク質

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20110509

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110707

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20130807

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20130820

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20131115

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20131122

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20140120

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20140507