JP2012511579A5 - - Google Patents
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- JP2012511579A5 JP2012511579A5 JP2011540854A JP2011540854A JP2012511579A5 JP 2012511579 A5 JP2012511579 A5 JP 2012511579A5 JP 2011540854 A JP2011540854 A JP 2011540854A JP 2011540854 A JP2011540854 A JP 2011540854A JP 2012511579 A5 JP2012511579 A5 JP 2012511579A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- rsv
- arginine
- vlp
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12112608P | 2008-12-09 | 2008-12-09 | |
| US61/121,126 | 2008-12-09 | ||
| US16907709P | 2009-04-14 | 2009-04-14 | |
| US61/169,077 | 2009-04-14 | ||
| US22478709P | 2009-07-10 | 2009-07-10 | |
| US61/224,787 | 2009-07-10 | ||
| PCT/US2009/067269 WO2010077717A1 (en) | 2008-12-09 | 2009-12-09 | Modified rsv f proteins and methods of their use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015124158A Division JP6162751B2 (ja) | 2008-12-09 | 2015-06-19 | 修飾ｒｓｖｆタンパク質及びその使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012511579A JP2012511579A (ja) | 2012-05-24 |
| JP2012511579A5 true JP2012511579A5 (https=) | 2013-01-17 |
| JP5813513B2 JP5813513B2 (ja) | 2015-11-17 |
Family
ID=42310119
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011540854A Active JP5813513B2 (ja) | 2008-12-09 | 2009-12-09 | 修飾ｒｓｖｆタンパク質及びその使用方法 |
| JP2015124158A Active JP6162751B2 (ja) | 2008-12-09 | 2015-06-19 | 修飾ｒｓｖｆタンパク質及びその使用方法 |
| JP2017118032A Active JP6462048B2 (ja) | 2008-12-09 | 2017-06-15 | 修飾ｒｓｖ ｆタンパク質及びその使用方法 |
| JP2018242108A Active JP6782289B2 (ja) | 2008-12-09 | 2018-12-26 | 修飾ｒｓｖ ｆタンパク質及びその使用方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015124158A Active JP6162751B2 (ja) | 2008-12-09 | 2015-06-19 | 修飾ｒｓｖｆタンパク質及びその使用方法 |
| JP2017118032A Active JP6462048B2 (ja) | 2008-12-09 | 2017-06-15 | 修飾ｒｓｖ ｆタンパク質及びその使用方法 |
| JP2018242108A Active JP6782289B2 (ja) | 2008-12-09 | 2018-12-26 | 修飾ｒｓｖ ｆタンパク質及びその使用方法 |
Country Status (23)
| Country | Link |
|---|---|
| US (7) | US8715692B2 (https=) |
| EP (3) | EP2370099B1 (https=) |
| JP (4) | JP5813513B2 (https=) |
| KR (2) | KR101691574B1 (https=) |
| CN (2) | CN106146671B (https=) |
| AU (1) | AU2009333484B2 (https=) |
| BR (1) | BRPI0922867B8 (https=) |
| CA (1) | CA2746228C (https=) |
| CY (2) | CY1117757T1 (https=) |
| DK (2) | DK2370099T3 (https=) |
| ES (3) | ES2582005T3 (https=) |
| HR (2) | HRP20160859T1 (https=) |
| HU (2) | HUE029037T2 (https=) |
| IL (2) | IL213450B (https=) |
| LT (1) | LT3067064T (https=) |
| MX (4) | MX345700B (https=) |
| PL (2) | PL2370099T3 (https=) |
| PT (2) | PT3067064T (https=) |
| RU (1) | RU2531510C2 (https=) |
| SG (2) | SG10201500161XA (https=) |
| SI (2) | SI2370099T1 (https=) |
| SM (1) | SMT202000411T1 (https=) |
| WO (1) | WO2010077717A1 (https=) |
Families Citing this family (67)
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| US20160000902A1 (en) * | 2003-07-11 | 2016-01-07 | Novavax, Inc. | Combination vaccine for respiratory syncytial virus and influenza |
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| US11446374B2 (en) | 2008-12-09 | 2022-09-20 | Novavax, Inc. | Modified RSV F proteins and methods of their use |
| CA2768186A1 (en) | 2009-07-15 | 2011-01-20 | Novartis Ag | Rsv f protein compositions and methods for making same |
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| KR101847908B1 (ko) * | 2010-11-05 | 2018-04-11 | 노바백스, 인코포레이티드 | 광견병 당단백질 바이러스-유사 입자(VLPs) |
| WO2012089231A1 (en) * | 2010-12-30 | 2012-07-05 | Okairòs Ag | Paramyxovirus vaccines |
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| CA2835644C (en) | 2011-05-13 | 2021-06-15 | Novartis Ag | Pre-fusion rsv f antigens |
| WO2013019800A1 (en) * | 2011-08-01 | 2013-02-07 | Emory University | Vlps containing ligands and methods related thereto |
| JP6085886B2 (ja) | 2011-08-29 | 2017-03-01 | 国立大学法人徳島大学 | Ｒｓｖ粘膜ワクチン |
| RU2014117068A (ru) * | 2011-09-30 | 2015-11-10 | Новавакс, Инк. | Вакцина на основе рекомбинантных наночастиц f из rsv против респираторно-синцитиального вируса |
| CN103239734B (zh) * | 2012-02-10 | 2016-02-24 | 北京艾棣维欣生物技术有限公司 | 用于预防和/或治疗呼吸道合胞病毒感染的疫苗 |
| KR102435054B1 (ko) | 2012-08-01 | 2022-08-22 | 버베리안 노딕 에이/에스 | 재조합 변형된 백시니아 바이러스 앙카라(ankara) (mva) 호흡기 신시티알 바이러스(rsv) 백신 |
| EP2922570A1 (en) | 2012-11-20 | 2015-09-30 | GlaxoSmithKline Biologicals SA | Rsv f prefusion trimers |
| KR20150138184A (ko) * | 2013-02-11 | 2015-12-09 | 노바백스, 인코포레이티드 | 호흡기 세포 융합 바이러스 및 인플루엔자를 위한 조합 백신 |
| EP3798310A1 (en) * | 2013-03-14 | 2021-03-31 | Emory University | Recombinant rsv with silent mutations, vaccines, and methods related thereto |
| DE102013004595A1 (de) * | 2013-03-15 | 2014-09-18 | Emergent Product Development Germany Gmbh | RSV-Impfstoffe |
| BR112016006122B1 (pt) | 2013-09-19 | 2023-11-14 | Novavax, Inc | COMPOSIÇÃO IMUNOGÊNICA COMPREENDENDO UMA NANOPARTÍCULA DO CORONAVÍRUS DA SÍNDROME RESPIRATÓRIA DO ORIENTE MÉDIO (MERS-CoV) |
| EP2974739A1 (en) | 2014-07-15 | 2016-01-20 | Novartis AG | RSVF trimerization domains |
| WO2015195961A1 (en) * | 2014-06-18 | 2015-12-23 | Georgia State University And Research Foundation, Inc. | Recombinant rsv reporter virus |
| US9969986B2 (en) * | 2014-08-08 | 2018-05-15 | Vlp Therapeutics, Llc | Virus like particle comprising modified envelope protein E3 |
| US9630994B2 (en) | 2014-11-03 | 2017-04-25 | University Of Washington | Polypeptides for use in self-assembling protein nanostructures |
| EA039065B1 (ru) | 2015-07-07 | 2021-11-29 | Янссен Вэксинс Энд Превеншн Б.В. | Вакцина против rsv |
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| RU2723039C2 (ru) | 2015-12-23 | 2020-06-08 | Пфайзер Инк. | Мутанты белка f rsv |
| JP7233928B2 (ja) | 2016-04-05 | 2023-03-07 | ヤンセン ファッシンズ アンド プリベンション ベーフェー | Ｒｓｖに対するワクチン |
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| CN109311946A (zh) | 2016-05-30 | 2019-02-05 | 扬森疫苗与预防公司 | 稳定化的融合前rsv f蛋白 |
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| EP3746090A4 (en) | 2018-01-29 | 2021-11-17 | ModernaTX, Inc. | RSV RNA Vaccines |
| WO2019169120A1 (en) | 2018-02-28 | 2019-09-06 | University Of Washington | Self-asssembling nanostructure vaccines |
| CN120227451A (zh) | 2018-03-19 | 2025-07-01 | 诺瓦瓦克斯股份有限公司 | 多价流感纳米颗粒疫苗 |
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| JP7614841B2 (ja) | 2018-04-03 | 2025-01-16 | サノフイ | 抗原性呼吸器合胞体ウイルスポリペプチド |
| EP3873517A4 (en) | 2018-10-29 | 2022-09-28 | Emory University | RSV VIRUS-LIKE PARTICLES AND METHODS OF PRODUCTION THEREOF |
| KR102725189B1 (ko) * | 2018-11-01 | 2024-10-31 | 에스케이바이오사이언스(주) | 재조합 호흡기 세포융합 바이러스 f 단백질 및 이를 포함하는 백신 조성물 |
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| EP3923983A4 (en) * | 2019-02-11 | 2023-02-22 | Emory University | CHIMERIC RSV AND HMPV F PROTEINS, IMMUNOGENIC COMPOSITIONS AND METHODS OF USE |
| EP3932424A4 (en) | 2019-02-28 | 2022-10-12 | KM Biologics Co., Ltd. | Rsv f/g chimeric vaccine |
| US10953089B1 (en) | 2020-01-27 | 2021-03-23 | Novavax, Inc. | Coronavirus vaccine formulations |
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| RU2531235C2 (ru) | 2013-02-15 | 2014-10-20 | Общество с ограниченной ответственностью "Универсальные БиоСистемы" (ООО "УБС") | Поливалентная вакцина против гриппа на основе гибридного белка |
| KR102236497B1 (ko) | 2013-04-25 | 2021-04-06 | 얀센 백신스 앤드 프리벤션 비.브이. | 안정화된 가용성 예비융합 ｒｓｖ ｆ 폴리펩타이드 |
| AU2014100888A4 (en) | 2014-08-07 | 2014-09-11 | Novartis Ag | Virus clearance and protein purification methods |
| WO2017000105A1 (zh) * | 2015-06-29 | 2017-01-05 | 尚平 | 便携式加湿器 |
| CA2996007A1 (en) | 2015-09-03 | 2017-03-09 | Novavax, Inc. | Vaccine compositions having improved stability and immunogenicity |
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