JP2012510457A5 - - Google Patents
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- JP2012510457A5 JP2012510457A5 JP2011538050A JP2011538050A JP2012510457A5 JP 2012510457 A5 JP2012510457 A5 JP 2012510457A5 JP 2011538050 A JP2011538050 A JP 2011538050A JP 2011538050 A JP2011538050 A JP 2011538050A JP 2012510457 A5 JP2012510457 A5 JP 2012510457A5
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- 239000013566 allergen Substances 0.000 claims 18
- 238000000034 method Methods 0.000 claims 17
- 108090000765 processed proteins & peptides Proteins 0.000 claims 16
- 235000018102 proteins Nutrition 0.000 claims 12
- 102000004169 proteins and genes Human genes 0.000 claims 12
- 108090000623 proteins and genes Proteins 0.000 claims 12
- 241000196324 Embryophyta Species 0.000 claims 8
- 239000000427 antigen Substances 0.000 claims 5
- 108091007433 antigens Proteins 0.000 claims 5
- 102000036639 antigens Human genes 0.000 claims 5
- 239000000428 dust Substances 0.000 claims 4
- 102000004196 processed proteins & peptides Human genes 0.000 claims 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 3
- XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical group SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 claims 3
- 230000001363 autoimmune Effects 0.000 claims 3
- PJUIMOJAAPLTRJ-UHFFFAOYSA-N monothioglycerol Chemical compound OCC(O)CS PJUIMOJAAPLTRJ-UHFFFAOYSA-N 0.000 claims 3
- 229940035024 thioglycerol Drugs 0.000 claims 3
- WZXXZHONLFRKGG-UHFFFAOYSA-N 2,3,4,5-tetrachlorothiophene Chemical compound ClC=1SC(Cl)=C(Cl)C=1Cl WZXXZHONLFRKGG-UHFFFAOYSA-N 0.000 claims 2
- 208000026872 Addison Disease Diseases 0.000 claims 2
- 241000223602 Alternaria alternata Species 0.000 claims 2
- 235000003129 Ambrosia artemisiifolia var elatior Nutrition 0.000 claims 2
- 206010002556 Ankylosing Spondylitis Diseases 0.000 claims 2
- 208000003343 Antiphospholipid Syndrome Diseases 0.000 claims 2
- 208000032467 Aplastic anaemia Diseases 0.000 claims 2
- 235000017060 Arachis glabrata Nutrition 0.000 claims 2
- 244000105624 Arachis hypogaea Species 0.000 claims 2
- 235000010777 Arachis hypogaea Nutrition 0.000 claims 2
- 235000018262 Arachis monticola Nutrition 0.000 claims 2
- 235000003826 Artemisia Nutrition 0.000 claims 2
- 235000003261 Artemisia vulgaris Nutrition 0.000 claims 2
- 206010003827 Autoimmune hepatitis Diseases 0.000 claims 2
- 235000018185 Betula X alpestris Nutrition 0.000 claims 2
- 235000018212 Betula X uliginosa Nutrition 0.000 claims 2
- 208000008439 Biliary Liver Cirrhosis Diseases 0.000 claims 2
- 208000033222 Biliary cirrhosis primary Diseases 0.000 claims 2
- 241000238657 Blattella germanica Species 0.000 claims 2
- 101100025811 Caenorhabditis elegans hch-1 gene Proteins 0.000 claims 2
- 244000132059 Carica parviflora Species 0.000 claims 2
- 235000014653 Carica parviflora Nutrition 0.000 claims 2
- 108010078791 Carrier Proteins Proteins 0.000 claims 2
- 102000014914 Carrier Proteins Human genes 0.000 claims 2
- 101710163595 Chaperone protein DnaK Proteins 0.000 claims 2
- 244000281762 Chenopodium ambrosioides Species 0.000 claims 2
- 208000015943 Coeliac disease Diseases 0.000 claims 2
- 208000011231 Crohn disease Diseases 0.000 claims 2
- 108010055622 Dermatophagoides farinae antigen f 1 Proteins 0.000 claims 2
- 108010082995 Dermatophagoides farinae antigen f 2 Proteins 0.000 claims 2
- 108010082990 Dermatophagoides farinae antigen f 7 Proteins 0.000 claims 2
- 108010061629 Dermatophagoides pteronyssinus antigen p 1 Proteins 0.000 claims 2
- 108010061608 Dermatophagoides pteronyssinus antigen p 2 Proteins 0.000 claims 2
- 108010061638 Dermatophagoides pteronyssinus antigen p 7 Proteins 0.000 claims 2
- 241000282324 Felis Species 0.000 claims 2
- 208000007465 Giant cell arteritis Diseases 0.000 claims 2
- 208000024869 Goodpasture syndrome Diseases 0.000 claims 2
- 206010072579 Granulomatosis with polyangiitis Diseases 0.000 claims 2
- 208000015023 Graves' disease Diseases 0.000 claims 2
- 208000035895 Guillain-Barré syndrome Diseases 0.000 claims 2
- 208000001204 Hashimoto Disease Diseases 0.000 claims 2
- 208000030836 Hashimoto thyroiditis Diseases 0.000 claims 2
- 101710178376 Heat shock 70 kDa protein Proteins 0.000 claims 2
- 101710152018 Heat shock cognate 70 kDa protein Proteins 0.000 claims 2
- 241000238631 Hexapoda Species 0.000 claims 2
- 101001124017 Homo sapiens Nuclear transport factor 2 Proteins 0.000 claims 2
- 206010021245 Idiopathic thrombocytopenic purpura Diseases 0.000 claims 2
- 208000011200 Kawasaki disease Diseases 0.000 claims 2
- 241001465754 Metazoa Species 0.000 claims 2
- 206010049567 Miller Fisher syndrome Diseases 0.000 claims 2
- 102100028418 Nuclear transport factor 2 Human genes 0.000 claims 2
- 208000005225 Opsoclonus-Myoclonus Syndrome Diseases 0.000 claims 2
- 208000003435 Optic Neuritis Diseases 0.000 claims 2
- 206010034277 Pemphigoid Diseases 0.000 claims 2
- 241000721454 Pemphigus Species 0.000 claims 2
- 208000031845 Pernicious anaemia Diseases 0.000 claims 2
- 102000012288 Phosphopyruvate Hydratase Human genes 0.000 claims 2
- 108010022181 Phosphopyruvate Hydratase Proteins 0.000 claims 2
- 206010036030 Polyarthritis Diseases 0.000 claims 2
- 208000012654 Primary biliary cholangitis Diseases 0.000 claims 2
- 102000011195 Profilin Human genes 0.000 claims 2
- 108050001408 Profilin Proteins 0.000 claims 2
- 101710171134 Protein Bet Proteins 0.000 claims 2
- 108010029485 Protein Isoforms Proteins 0.000 claims 2
- 102000001708 Protein Isoforms Human genes 0.000 claims 2
- 208000033464 Reiter syndrome Diseases 0.000 claims 2
- 244000124765 Salsola kali Species 0.000 claims 2
- 235000007658 Salsola kali Nutrition 0.000 claims 2
- 208000021386 Sjogren Syndrome Diseases 0.000 claims 2
- 210000001744 T-lymphocyte Anatomy 0.000 claims 2
- 208000001106 Takayasu Arteritis Diseases 0.000 claims 2
- 208000031981 Thrombocytopenic Idiopathic Purpura Diseases 0.000 claims 2
- 102100029887 Translationally-controlled tumor protein Human genes 0.000 claims 2
- 101710157927 Translationally-controlled tumor protein Proteins 0.000 claims 2
- 101710175870 Translationally-controlled tumor protein homolog Proteins 0.000 claims 2
- 102000004142 Trypsin Human genes 0.000 claims 2
- 108090000631 Trypsin Proteins 0.000 claims 2
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 claims 2
- 208000002552 acute disseminated encephalomyelitis Diseases 0.000 claims 2
- 230000000961 alloantigen Effects 0.000 claims 2
- 235000001014 amino acid Nutrition 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 235000003484 annual ragweed Nutrition 0.000 claims 2
- 239000003242 anti bacterial agent Substances 0.000 claims 2
- 229940088710 antibiotic agent Drugs 0.000 claims 2
- 244000030166 artemisia Species 0.000 claims 2
- 235000009052 artemisia Nutrition 0.000 claims 2
- 206010003246 arthritis Diseases 0.000 claims 2
- 201000003710 autoimmune thrombocytopenic purpura Diseases 0.000 claims 2
- 235000006263 bur ragweed Nutrition 0.000 claims 2
- 235000014633 carbohydrates Nutrition 0.000 claims 2
- 150000001720 carbohydrates Chemical class 0.000 claims 2
- 208000025302 chronic primary adrenal insufficiency Diseases 0.000 claims 2
- 235000003488 common ragweed Nutrition 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 230000007613 environmental effect Effects 0.000 claims 2
- 239000013568 food allergen Substances 0.000 claims 2
- 239000013569 fungal allergen Substances 0.000 claims 2
- 210000000265 leukocyte Anatomy 0.000 claims 2
- 150000002632 lipids Chemical class 0.000 claims 2
- 206010025135 lupus erythematosus Diseases 0.000 claims 2
- 208000001725 mucocutaneous lymph node syndrome Diseases 0.000 claims 2
- 201000006417 multiple sclerosis Diseases 0.000 claims 2
- 206010028417 myasthenia gravis Diseases 0.000 claims 2
- 201000003631 narcolepsy Diseases 0.000 claims 2
- 235000020232 peanut Nutrition 0.000 claims 2
- 208000030428 polyarticular arthritis Diseases 0.000 claims 2
- 235000009736 ragweed Nutrition 0.000 claims 2
- 208000002574 reactive arthritis Diseases 0.000 claims 2
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 2
- 206010043207 temporal arteritis Diseases 0.000 claims 2
- 206010043778 thyroiditis Diseases 0.000 claims 2
- 239000003053 toxin Substances 0.000 claims 2
- 231100000765 toxin Toxicity 0.000 claims 2
- 108700012359 toxins Proteins 0.000 claims 2
- 239000012588 trypsin Substances 0.000 claims 2
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 claims 1
- 208000023328 Basedow disease Diseases 0.000 claims 1
- 241000282465 Canis Species 0.000 claims 1
- 241000282472 Canis lupus familiaris Species 0.000 claims 1
- 208000003807 Graves Disease Diseases 0.000 claims 1
- 206010018910 Haemolysis Diseases 0.000 claims 1
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 claims 1
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims 1
- 230000005784 autoimmunity Effects 0.000 claims 1
- 208000035623 congenital anemia Diseases 0.000 claims 1
- 125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 claims 1
- 210000004392 genitalia Anatomy 0.000 claims 1
- 230000008588 hemolysis Effects 0.000 claims 1
- 208000007475 hemolytic anemia Diseases 0.000 claims 1
- 230000003053 immunization Effects 0.000 claims 1
- 238000002649 immunization Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000035935 pregnancy Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0821806.7A GB0821806D0 (en) | 2008-11-28 | 2008-11-28 | Compositions with reduced dimer formation |
| GB0821806.7 | 2008-11-28 | ||
| PCT/GB2009/002767 WO2010061193A2 (en) | 2008-11-28 | 2009-11-27 | Compositions with reduced dimer formation |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014180264A Division JP5905942B2 (ja) | 2008-11-28 | 2014-09-04 | 二量体形成の減少した組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012510457A JP2012510457A (ja) | 2012-05-10 |
| JP2012510457A5 true JP2012510457A5 (enExample) | 2013-01-24 |
| JP5612592B2 JP5612592B2 (ja) | 2014-10-22 |
Family
ID=40262373
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011538050A Expired - Fee Related JP5612592B2 (ja) | 2008-11-28 | 2009-11-27 | 二量体形成の減少した組成物 |
| JP2014180264A Expired - Fee Related JP5905942B2 (ja) | 2008-11-28 | 2014-09-04 | 二量体形成の減少した組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014180264A Expired - Fee Related JP5905942B2 (ja) | 2008-11-28 | 2014-09-04 | 二量体形成の減少した組成物 |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US9180098B2 (enExample) |
| EP (2) | EP2649990A1 (enExample) |
| JP (2) | JP5612592B2 (enExample) |
| KR (1) | KR101669693B1 (enExample) |
| CN (1) | CN102227214B (enExample) |
| AU (1) | AU2009321358B2 (enExample) |
| BR (1) | BRPI0921541A2 (enExample) |
| CA (1) | CA2744587C (enExample) |
| DK (1) | DK2373293T3 (enExample) |
| EA (1) | EA019923B1 (enExample) |
| ES (1) | ES2427855T5 (enExample) |
| GB (2) | GB0821806D0 (enExample) |
| HR (1) | HRP20130933T1 (enExample) |
| IL (1) | IL213088A (enExample) |
| MX (1) | MX2011005530A (enExample) |
| NZ (1) | NZ593145A (enExample) |
| PL (1) | PL2373293T3 (enExample) |
| SG (1) | SG171438A1 (enExample) |
| SI (1) | SI2373293T1 (enExample) |
| WO (1) | WO2010061193A2 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0821806D0 (en) | 2008-11-28 | 2009-01-07 | Circassia Ltd | Compositions with reduced dimer formation |
| WO2013092985A1 (en) * | 2011-12-23 | 2013-06-27 | Novartis Ag | Stable compositions for immunising against staphylococcus aureus |
| GB201208293D0 (en) * | 2012-05-11 | 2012-06-20 | Circassia Ltd | Hydrochlorice salt of peptide |
| GB201209862D0 (en) * | 2012-06-01 | 2012-07-18 | Circassia Ltd | Cladosporium peptides |
| GB201209868D0 (en) * | 2012-06-01 | 2012-07-18 | Circassia Ltd | Alternaria peptides |
| EP2698162A1 (en) * | 2012-08-15 | 2014-02-19 | Credentis AG | Method for producing a composition for treating a tooth lesion |
| DK2914286T3 (da) | 2012-10-30 | 2021-11-08 | Aravax Pty Ltd | Hidtil ukendte immunterapeutiske molekyler og anvendelser deraf |
| GB201301457D0 (en) | 2013-01-28 | 2013-03-13 | Fluorogenics Ltd | Freeze-dried composition |
| CN103040769A (zh) * | 2013-02-05 | 2013-04-17 | 南京碧迪可医药科技有限公司 | 一种稳定的诺卡沙星粉针冻干剂 |
| KR20160075532A (ko) | 2013-09-25 | 2016-06-29 | 아라백스 피티와이 엘티디 | 신규한 면역치료제 조성물 및 이의 용도 |
| CN103656635B (zh) * | 2013-12-05 | 2016-05-18 | 安徽润敏江生物科技有限公司 | 一种德国小蠊过敏原制剂的制备方法 |
| DK3129001T3 (da) * | 2014-04-10 | 2020-01-20 | Asit Biotech S A | Hsp-fri fremstilling af allergen |
| CN107207622B (zh) * | 2015-02-04 | 2021-09-28 | 苏黎世大学 | Hla-b27同二聚体用于癌症治疗的用途 |
| EP3373870A4 (en) | 2015-11-12 | 2019-07-10 | University Of Virginia Patent Foundation | COMPOSITIONS AND METHODS FOR VAS OCCLUSAL CONSUMER PREVENTION AND THEIR REVERSAL |
| US10925969B2 (en) | 2015-11-13 | 2021-02-23 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Service | Anti-BCMA polypeptides and proteins |
| WO2017153438A1 (en) | 2016-03-08 | 2017-09-14 | Universität Zürich | Hla-b57 open conformers |
| JP7010439B2 (ja) | 2016-08-10 | 2022-01-26 | ウニヴェルズィテート チューリッヒ | ＭＨＣクラスＩａオープンコンフォーマー |
| CN110381854A (zh) | 2017-01-05 | 2019-10-25 | 考恩特兰有限公司 | 用于植入和逆转刺激响应性植入物的方法 |
| US12383421B2 (en) | 2017-01-05 | 2025-08-12 | Contraline, Inc. | Contraceptive devices |
| KR102646145B1 (ko) | 2018-05-31 | 2024-03-11 | 주식회사 엑소코바이오 | 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 모공 축소용 조성물 |
| KR102058961B1 (ko) | 2018-07-28 | 2019-12-24 | 주식회사 엑소코바이오 | 엑소좀의 동결건조 방법 |
| KR102163806B1 (ko) | 2018-07-30 | 2020-10-07 | 주식회사 엑소코바이오 | 줄기세포 유래의 엑소좀을 유효성분으로 포함하는 피지분비 감소용 조성물 |
| CA3117577A1 (en) | 2018-11-13 | 2020-05-22 | Contraline, Inc. | Systems and methods for delivering biomaterials |
| US20240060082A1 (en) * | 2021-01-22 | 2024-02-22 | Syngenta Crop Protection Ag | Soybean Engineered Resistance |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0044532B1 (en) * | 1980-07-18 | 1986-04-23 | E.I. Du Pont De Nemours And Company | Monothioglycerol as thiol-protector in lyophilized materials |
| US4442212A (en) | 1980-11-10 | 1984-04-10 | E. I. Du Pont De Nemours & Company | Monothioglycerol as thiol-protector in lyophilized materials |
| JPS6197229A (ja) | 1984-10-18 | 1986-05-15 | Chugai Pharmaceut Co Ltd | 安定なエリトロポエチン製剤 |
| US4855407A (en) | 1985-04-11 | 1989-08-08 | Alpha-1 Biomedicals, Inc. | Solid phase process for synthesizing peptides |
| JP2787162B2 (ja) * | 1989-08-24 | 1998-08-13 | フマキラー株式会社 | 精製ダニアレルゲン |
| AU650249B2 (en) * | 1989-11-03 | 1994-06-16 | Immulogic Pharmaceutical Corporation | A human T cell reactive feline protein (TRFP) isolated from house dust and uses therefor |
| EP0623168B1 (en) | 1991-10-16 | 2009-09-30 | Merck Patent GmbH | T cell epitopes of the major allergens from dermatophagoides (house dust mite) |
| EP0770681A3 (en) | 1992-04-09 | 1997-06-04 | Immulogic Pharmaceutical Corporation | T cell epitopes of the major allergens from ambrosia artemisiifolia |
| US5480972A (en) | 1992-10-30 | 1996-01-02 | The University Of Melbourne | Allergenic proteins from Johnson grass pollen |
| US5939283A (en) | 1992-12-31 | 1999-08-17 | Immulogic Pharmaceutical Corporation | Allergenic proteins and peptides from dog dander and uses therefor |
| JPH10505356A (ja) | 1994-09-02 | 1998-05-26 | イミユロジク・フアーマシユーチカル・コーポレーシヨン | ヒトへの投与のための組成物および方法、抗原特異的免疫応答のダウンレギュレーションを行うことが可能なペプチド |
| DE19508192A1 (de) | 1995-03-09 | 1996-09-12 | Behringwerke Ag | Stabile Transglutaminasepräparate und Verfahren zu ihrer Herstellung |
| CN1283997A (zh) | 1997-12-22 | 2001-02-14 | 人类基因组科学公司 | 角质形成细胞生长因子－2制剂 |
| JP2002500198A (ja) * | 1998-01-09 | 2002-01-08 | サーカシア リミテッド | 脱感作のための方法及び組成物 |
| WO2002017956A2 (en) | 2000-08-31 | 2002-03-07 | Chiron Corporation | Stabilized fgf formulations containing reducing agents |
| EP2322165A1 (en) | 2001-11-13 | 2011-05-18 | Genentech, Inc. | Apo2 ligand/TRAIL formulations |
| JP4874522B2 (ja) | 2001-12-05 | 2012-02-15 | サーカッシア リミテッド | 免疫療法および系 |
| JP2005526084A (ja) * | 2002-03-15 | 2005-09-02 | ナットイムネ・アクティーゼルスカブ | マンノース結合レクチンを含む医薬組成物 |
| WO2003093299A2 (en) | 2002-05-06 | 2003-11-13 | Thomas Jefferson University | Insulin-associated peptides with effects on cerebral health |
| CA2545458A1 (en) | 2003-11-10 | 2005-05-26 | Arriva-Prometic Inc. | Dry recombinant human alpha 1-antitrypsin formulation |
| US7842661B2 (en) | 2003-11-24 | 2010-11-30 | Novo Nordisk A/S | Glycopegylated erythropoietin formulations |
| DE602004005564T2 (de) | 2003-12-31 | 2007-12-13 | Orthologic Corp., Tempe | Pharmazeutische Zusammensetzung für Thrombinpeptidderivaten |
| JP2007277094A (ja) * | 2004-06-29 | 2007-10-25 | Chemo Sero Therapeut Res Inst | 改変ダニ主要アレルゲン含有医薬組成物 |
| US20060029551A1 (en) | 2004-08-05 | 2006-02-09 | Kui Liu | Stable particle formulations of erythropoietin receptor agonists |
| KR20070100832A (ko) * | 2005-02-01 | 2007-10-11 | 아테뉴온, 엘엘씨 | 항혈관신생 ｐｈｓｃｎ 펩티드를 함유하는 조성물 |
| EP2007421A2 (en) | 2005-03-04 | 2008-12-31 | Dynavax Technologies Corporation | Vaccines comprising oligonucleotides having immunostimulatory sequences (iss) wherein the iss are conjugated to antigens and stabilized by buffer conditions and further excipients. |
| RU2008117396A (ru) * | 2005-10-04 | 2009-11-10 | Альк-Абелло А/С (Dk) | Твердая вакцинная композиция |
| EP1958645A1 (en) | 2007-02-13 | 2008-08-20 | Biomay AG | Peptides derived from the major allergen of ragweed (Ambrosia artemisiifolia) and uses thereof |
| US8148105B2 (en) | 2007-03-16 | 2012-04-03 | The Board Of Trustees Of The Leland Stanford Junior University | Scaleable manufacturing process for cysteine endoprotease B, isoform 2 |
| GB0710529D0 (en) | 2007-06-01 | 2007-07-11 | Circassia Ltd | Vaccine |
| ES2402956T3 (es) | 2007-08-15 | 2013-05-10 | Circassia Limited | Péptido con formación de dímeros reducida |
| GB0821806D0 (en) | 2008-11-28 | 2009-01-07 | Circassia Ltd | Compositions with reduced dimer formation |
-
2008
- 2008-11-28 GB GBGB0821806.7A patent/GB0821806D0/en not_active Ceased
-
2009
- 2009-11-27 HR HRP20130933AT patent/HRP20130933T1/hr unknown
- 2009-11-27 GB GB1114575.2A patent/GB2479515B/en not_active Expired - Fee Related
- 2009-11-27 US US13/131,505 patent/US9180098B2/en not_active Expired - Fee Related
- 2009-11-27 PL PL09760560T patent/PL2373293T3/pl unknown
- 2009-11-27 DK DK09760560.4T patent/DK2373293T3/da active
- 2009-11-27 EP EP13176176.9A patent/EP2649990A1/en not_active Withdrawn
- 2009-11-27 BR BRPI0921541A patent/BRPI0921541A2/pt not_active IP Right Cessation
- 2009-11-27 MX MX2011005530A patent/MX2011005530A/es active IP Right Grant
- 2009-11-27 CA CA2744587A patent/CA2744587C/en not_active Expired - Fee Related
- 2009-11-27 EP EP09760560.4A patent/EP2373293B2/en not_active Not-in-force
- 2009-11-27 EA EA201100865A patent/EA019923B1/ru not_active IP Right Cessation
- 2009-11-27 KR KR1020117014702A patent/KR101669693B1/ko not_active Expired - Fee Related
- 2009-11-27 ES ES09760560.4T patent/ES2427855T5/es active Active
- 2009-11-27 AU AU2009321358A patent/AU2009321358B2/en not_active Ceased
- 2009-11-27 CN CN200980147921.8A patent/CN102227214B/zh not_active Expired - Fee Related
- 2009-11-27 SG SG2011038718A patent/SG171438A1/en unknown
- 2009-11-27 JP JP2011538050A patent/JP5612592B2/ja not_active Expired - Fee Related
- 2009-11-27 SI SI200930730T patent/SI2373293T1/sl unknown
- 2009-11-27 WO PCT/GB2009/002767 patent/WO2010061193A2/en not_active Ceased
- 2009-11-27 NZ NZ593145A patent/NZ593145A/xx not_active IP Right Cessation
-
2011
- 2011-05-24 IL IL213088A patent/IL213088A/en not_active IP Right Cessation
-
2014
- 2014-09-04 JP JP2014180264A patent/JP5905942B2/ja not_active Expired - Fee Related
-
2015
- 2015-10-06 US US14/876,548 patent/US9375470B2/en not_active Expired - Fee Related
-
2016
- 2016-05-24 US US15/163,211 patent/US20160367660A1/en not_active Abandoned
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