JP2012506389A5 - - Google Patents

Download PDF

Info

Publication number
JP2012506389A5
JP2012506389A5 JP2011532512A JP2011532512A JP2012506389A5 JP 2012506389 A5 JP2012506389 A5 JP 2012506389A5 JP 2011532512 A JP2011532512 A JP 2011532512A JP 2011532512 A JP2011532512 A JP 2011532512A JP 2012506389 A5 JP2012506389 A5 JP 2012506389A5
Authority
JP
Japan
Prior art keywords
het
conh
hal
atoms
mono
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2011532512A
Other languages
English (en)
Japanese (ja)
Other versions
JP5662325B2 (ja
JP2012506389A (ja
Filing date
Publication date
Priority claimed from DE102008052943A external-priority patent/DE102008052943A1/de
Application filed filed Critical
Publication of JP2012506389A publication Critical patent/JP2012506389A/ja
Publication of JP2012506389A5 publication Critical patent/JP2012506389A5/ja
Application granted granted Critical
Publication of JP5662325B2 publication Critical patent/JP5662325B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2011532512A 2008-10-23 2009-09-24 アザインドール誘導体 Expired - Fee Related JP5662325B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102008052943.5 2008-10-23
DE102008052943A DE102008052943A1 (de) 2008-10-23 2008-10-23 Azaindolderivate
PCT/EP2009/006911 WO2010046013A1 (de) 2008-10-23 2009-09-24 Azaindolderivate

Publications (3)

Publication Number Publication Date
JP2012506389A JP2012506389A (ja) 2012-03-15
JP2012506389A5 true JP2012506389A5 (enExample) 2012-11-08
JP5662325B2 JP5662325B2 (ja) 2015-01-28

Family

ID=41268294

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011532512A Expired - Fee Related JP5662325B2 (ja) 2008-10-23 2009-09-24 アザインドール誘導体

Country Status (9)

Country Link
US (1) US20110207732A1 (enExample)
EP (1) EP2342202B1 (enExample)
JP (1) JP5662325B2 (enExample)
AU (1) AU2009306795B2 (enExample)
CA (1) CA2741428C (enExample)
DE (1) DE102008052943A1 (enExample)
ES (1) ES2559427T3 (enExample)
IL (1) IL212285A0 (enExample)
WO (1) WO2010046013A1 (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5596364B2 (ja) * 2009-02-19 2014-09-24 住友化学株式会社 含窒素有機化合物及びそれを用いた有機エレクトロルミネッセンス素子
WO2011075613A1 (en) * 2009-12-18 2011-06-23 Sanofi Azaindole derivatives, their preparation and their therapeutic application
DE102010050558A1 (de) * 2010-11-05 2012-05-10 Merck Patent Gmbh 1H-Pyrrolo[2,3-b]pyridinderivate
JP5902293B2 (ja) 2011-04-25 2016-04-13 アッシャー・サード・イニシアティブ・インコーポレイテッド ピラゾロピリダジンおよび網膜変性疾患およびアッシャー症候群に伴う聴覚損失を治療するための方法
CN103958495B (zh) * 2011-06-09 2018-06-22 理森制药股份公司 作为gpr-119的调节剂的化合物
GB201217285D0 (en) * 2012-09-27 2012-11-14 Univ Central Lancashire Indole derivatives
US9227976B2 (en) 2012-10-25 2016-01-05 Usher Iii Initiative, Inc. Pyrazolopyridazines and methods for treating retinal-degenerative diseases and hearing loss associated with usher syndrome
US9738637B2 (en) * 2013-03-12 2017-08-22 Celgene Quantical Research, Inc. Histone demethylase inhibitors
US9499551B2 (en) 2014-01-24 2016-11-22 Confluence Life Sciences, Inc. Substituted pyrrolo[2,3-b]pyridines for treating cancer or inflammatory diseases
UY36122A (es) 2014-05-15 2016-01-08 Iteos Therapeutics ?derivados de pirrolidina-2,5-diona, composiciones farmacéuticas y métodos para usar como inhibidores ido1?
TW201630907A (zh) * 2014-12-22 2016-09-01 必治妥美雅史谷比公司 ＴＧＦβＲ拮抗劑
US9695200B2 (en) 2015-01-23 2017-07-04 Confluence Life Sciences, Inc. Heterocyclic ITK inhibitors for treating inflammation and cancer
EP3271354A1 (en) 2015-03-17 2018-01-24 Pfizer Inc Novel 3-indol substituted derivatives, pharmaceutical compositions and methods for use
CA2994917A1 (en) 2015-08-10 2017-02-16 Pfizer Inc. 3-indol substituted derivatives, pharmaceutical compositions and methods for use
EP3423443B1 (en) * 2016-03-01 2020-08-19 Novartis AG Cyano-substituted indole compounds and uses thereof as lsd1 inhibitors
KR102444835B1 (ko) * 2016-05-26 2022-09-19 리커리엄 아이피 홀딩스, 엘엘씨 Egfr 억제제 화합물
CN110582488A (zh) * 2016-09-30 2019-12-17 诺华股份有限公司 具有增强功效的免疫效应细胞疗法
WO2018210660A1 (en) 2017-05-15 2018-11-22 Basf Se Heteroaryl compounds as agrochemical fungicides
WO2018210658A1 (en) 2017-05-15 2018-11-22 Basf Se Heteroaryl compounds as agrochemical fungicides
WO2018210659A1 (en) 2017-05-15 2018-11-22 Basf Se Heteroaryl compounds as agrochemical fungicides
WO2018210661A1 (en) 2017-05-15 2018-11-22 Basf Se Heteroaryl compounds as agrochemical fungicides
WO2019057660A1 (en) 2017-09-25 2019-03-28 Basf Se INDOLE AND AZAINDOLE COMPOUNDS HAVING 6-CHANNEL SUBSTITUTED ARYL AND HETEROARYL CYCLES AS AGROCHEMICAL FUNGICIDES
EP3730489A1 (en) 2019-04-25 2020-10-28 Basf Se Heteroaryl compounds as agrochemical fungicides
KR102513463B1 (ko) * 2020-11-26 2023-03-29 주식회사 에스앤케이테라퓨틱스 엔도솜 톨-유사 수용체를 제어하는 신규 소분자 화합물 및 이를 이용한 자가면역질환 치료제
CN116332940B (zh) * 2023-02-14 2024-09-13 广西民族大学 一种7-脱氮嘌呤衍生物及其制备方法和应用
CN121263414A (zh) * 2023-05-26 2026-01-02 上海艾力斯医药科技股份有限公司 杂芳环类化合物、其药物组合物及其应用

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3009A (en) * 1843-03-21 Lard-lamp
US7004A (en) * 1850-01-08 Connecting ctjttees to shafts of boeing instetjments
US3022A (en) * 1843-03-30 Machine for bending stibrups for paddle-wheels of steam and other
GB9624482D0 (en) 1995-12-18 1997-01-15 Zeneca Phaema S A Chemical compounds
DE69720965T2 (de) 1996-02-13 2004-02-05 Astrazeneca Ab Chinazolinderivate und deren verwendung als vegf hemmer
PT885198E (pt) 1996-03-05 2002-06-28 Astrazeneca Ab Derivados de 4-anilinoquinazolina
GB9718972D0 (en) 1996-09-25 1997-11-12 Zeneca Ltd Chemical compounds
PT948495E (pt) * 1996-11-19 2004-08-31 Amgen Inc Agentes anti-inflamatorios de pirrolo fundido substituidos em arilo e heteroarilo
GB9714249D0 (en) 1997-07-08 1997-09-10 Angiogene Pharm Ltd Vascular damaging agents
PL340412A1 (en) 1997-10-20 2001-01-29 Hoffmann La Roche Bicyclic kinase inhibitors
US6187777B1 (en) * 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
GB9900334D0 (en) 1999-01-07 1999-02-24 Angiogene Pharm Ltd Tricylic vascular damaging agents
GB9900752D0 (en) 1999-01-15 1999-03-03 Angiogene Pharm Ltd Benzimidazole vascular damaging agents
DE19951360A1 (de) * 1999-10-26 2001-05-03 Aventis Pharma Gmbh Substituierte Indole
JP2001122855A (ja) * 1999-10-27 2001-05-08 Japan Tobacco Inc インドール化合物及びその医薬用途
CA2406979A1 (en) 2000-05-31 2001-12-06 Astrazeneca Ab Indole derivatives with vascular damaging activity
CZ200331A3 (cs) 2000-07-07 2003-04-16 Angiogene Pharmaceuticals Limited Deriváty kolchinolu jako inhibitory angiogeneze, způsob jejich přípravy a farmaceutická kompozice, která je obsahuje
IL153484A0 (en) 2000-07-07 2003-07-06 Angiogene Pharm Ltd Colchinol derivatives as angiogenesis inhibitors
AUPR283801A0 (en) * 2001-02-01 2001-03-01 Australian National University, The Chemical compounds and methods
SE0202463D0 (sv) 2002-08-14 2002-08-14 Astrazeneca Ab Novel compounds
US7393851B2 (en) 2002-10-09 2008-07-01 Scios, Inc. Azaindole derivatives as inhibitors of p38 kinase
WO2004078756A2 (en) 2003-03-06 2004-09-16 Eisai Co., Ltd. Jnk inhibitors
PT1696920E (pt) 2003-12-19 2015-01-14 Plexxikon Inc Compostos e métodos para o desenvolvimento de moduladores de ret
GB0405055D0 (en) 2004-03-05 2004-04-07 Eisai London Res Lab Ltd JNK inhibitors
KR101298967B1 (ko) 2004-03-30 2013-09-02 버텍스 파마슈티칼스 인코포레이티드 Ｊａｋ 및 기타 단백질 키나제의 억제제로서 유용한 아자인돌
AU2005260689B2 (en) 2004-06-30 2012-05-10 Vertex Pharmaceuticals Incorporated Azaindoles useful as inhibitors of protein kinases
CA2575808A1 (en) 2004-08-02 2006-02-16 Osi Pharmaceuticals, Inc. Aryl-amino substituted pyrrolopyrimidine multi-kinase inhibiting compounds
WO2006112828A1 (en) 2005-04-15 2006-10-26 Scios, Inc. Azaindole derivatives as inhibitors of p38 kinase
FR2884821B1 (fr) 2005-04-26 2007-07-06 Aventis Pharma Sa Pyrrolopyridines substitues, compositions les contenant, procede de fabrication et utilisation
KR20080016659A (ko) 2005-05-20 2008-02-21 버텍스 파마슈티칼스 인코포레이티드 단백질 키나제의 억제제로서 유용한 피롤로피리딘
PL1893612T3 (pl) 2005-06-22 2012-01-31 Plexxikon Inc Pochodne pirolo-[2,3-b]pirydyny jako inhibitory kinazy białkowej
CN102127078A (zh) 2005-07-14 2011-07-20 安斯泰来制药株式会社 Janus激酶3的杂环类抑制剂
JP5071374B2 (ja) 2005-07-14 2012-11-14 アステラス製薬株式会社 ヘテロ環ヤヌスキナーゼ３阻害剤
US8119655B2 (en) 2005-10-07 2012-02-21 Takeda Pharmaceutical Company Limited Kinase inhibitors
EP1963320A1 (en) 2005-12-07 2008-09-03 OSI Pharmaceuticals, Inc. Pyrrolopyridine kinase inhibiting compounds
WO2007076320A2 (en) 2005-12-22 2007-07-05 Smithkline Beecham Corporation Compounds
ES2408318T3 (es) 2005-12-23 2013-06-20 Glaxosmithkline Llc Inhibidores de azaindol de las cinasas Aurora
EP2029593A1 (en) 2006-05-22 2009-03-04 AstraZeneca AB Indole derivatives
WO2008014249A2 (en) 2006-07-24 2008-01-31 Sanofi-Aventis Improved preparations of 2 -substituted pyrrolo [2, 3-b] pyrazine ( 4, 7 -diazaindole ) compounds
GB0708141D0 (en) * 2007-04-26 2007-06-06 Syngenta Participations Ag Improvements in or relating to organic compounds

Similar Documents

Publication Publication Date Title
JP2012506389A5 (enExample)
JP2014520767A5 (enExample)
JP2012532899A5 (enExample)
JP2012092103A5 (enExample)
HRP20200648T1 (hr) Derivati sulfamoilpirolamida i njihova uporaba kao lijekova za liječenje hepatitisa b
MX375261B (es) Compuestos aromaticos sustituidos para el tratamiento de la fibrosis pulmonar, la fibrosis hepatica, la fibrosis de la piel y la fibrosis cardiaca.
JP2016514159A5 (enExample)
JP2015536947A5 (enExample)
JP2012532901A5 (enExample)
AR082728A1 (es) Imidazolonilquinolinas utiles para tratar el cancer, composiciones farmaceuticas que las contienen, proceso de sintesis, intermediarios de dicha sintesis y procedimiento para prepararlos
JP2013521295A5 (enExample)
HRP20161103T1 (hr) Kemijski spojevi
JP2010095546A5 (enExample)
FI3738434T3 (fi) Välituotteita substituoitujen bentsaldehydiyhdisteiden saamiseksi ja menetelmiä niiden käyttöön kudosten hapetuksen lisäämiseksi
JP2016006118A5 (enExample)
ES2538364T3 (es) Sales y polimorfos de un compuesto de tetraciclina
JP2013532687A5 (enExample)
JP2012111953A5 (enExample)
JP2016505614A5 (enExample)
JP2013032389A5 (enExample)
JP2018533593A5 (enExample)
JP2013544860A5 (enExample)
JP2011518833A5 (enExample)
JP2015517532A5 (enExample)
EP3412668A3 (en) A selective inhibitor of phosphatidylinositol 3-kinase-gamma