JP2012506389A5 - - Google Patents

Download PDF

Info

Publication number
JP2012506389A5
JP2012506389A5 JP2011532512A JP2011532512A JP2012506389A5 JP 2012506389 A5 JP2012506389 A5 JP 2012506389A5 JP 2011532512 A JP2011532512 A JP 2011532512A JP 2011532512 A JP2011532512 A JP 2011532512A JP 2012506389 A5 JP2012506389 A5 JP 2012506389A5
Authority
JP
Japan
Prior art keywords
het
conh
hal
atoms
mono
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2011532512A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012506389A (ja
JP5662325B2 (ja
Filing date
Publication date
Priority claimed from DE102008052943A external-priority patent/DE102008052943A1/de
Application filed filed Critical
Publication of JP2012506389A publication Critical patent/JP2012506389A/ja
Publication of JP2012506389A5 publication Critical patent/JP2012506389A5/ja
Application granted granted Critical
Publication of JP5662325B2 publication Critical patent/JP5662325B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2011532512A 2008-10-23 2009-09-24 アザインドール誘導体 Expired - Fee Related JP5662325B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102008052943.5 2008-10-23
DE102008052943A DE102008052943A1 (de) 2008-10-23 2008-10-23 Azaindolderivate
PCT/EP2009/006911 WO2010046013A1 (de) 2008-10-23 2009-09-24 Azaindolderivate

Publications (3)

Publication Number Publication Date
JP2012506389A JP2012506389A (ja) 2012-03-15
JP2012506389A5 true JP2012506389A5 (enExample) 2012-11-08
JP5662325B2 JP5662325B2 (ja) 2015-01-28

Family

ID=41268294

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011532512A Expired - Fee Related JP5662325B2 (ja) 2008-10-23 2009-09-24 アザインドール誘導体

Country Status (9)

Country Link
US (1) US20110207732A1 (enExample)
EP (1) EP2342202B1 (enExample)
JP (1) JP5662325B2 (enExample)
AU (1) AU2009306795B2 (enExample)
CA (1) CA2741428C (enExample)
DE (1) DE102008052943A1 (enExample)
ES (1) ES2559427T3 (enExample)
IL (1) IL212285A0 (enExample)
WO (1) WO2010046013A1 (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5596364B2 (ja) * 2009-02-19 2014-09-24 住友化学株式会社 含窒素有機化合物及びそれを用いた有機エレクトロルミネッセンス素子
WO2011075613A1 (en) * 2009-12-18 2011-06-23 Sanofi Azaindole derivatives, their preparation and their therapeutic application
DE102010050558A1 (de) * 2010-11-05 2012-05-10 Merck Patent Gmbh 1H-Pyrrolo[2,3-b]pyridinderivate
CA2834049C (en) 2011-04-25 2018-05-22 Usher Iii Initiative, Inc. Pyrazolopyridazines and methods for treating retinal-degenerative diseases and hearing loss associated with usher syndrome
AU2012267556B9 (en) * 2011-06-09 2017-05-11 Rhizen Pharmaceuticals Sa Novel compounds as modulators of GPR-119
GB201217285D0 (en) * 2012-09-27 2012-11-14 Univ Central Lancashire Indole derivatives
US9227976B2 (en) 2012-10-25 2016-01-05 Usher Iii Initiative, Inc. Pyrazolopyridazines and methods for treating retinal-degenerative diseases and hearing loss associated with usher syndrome
US9738637B2 (en) * 2013-03-12 2017-08-22 Celgene Quantical Research, Inc. Histone demethylase inhibitors
CA2936551A1 (en) 2014-01-24 2015-07-30 Confluence Life Sciences, Inc. Substituted pyrrolopyridines and pyrrolopyrazines for treating cancer or inflammatory diseases
TN2016000501A1 (en) 2014-05-15 2018-04-04 Iteos Therapeutics Pyrrolidine-2,5-dione derivatives, pharmaceutical compositions and methods for use as ido1 inhibitors.
AR103232A1 (es) 2014-12-22 2017-04-26 Bristol Myers Squibb Co ANTAGONISTAS DE TGFbR
HK1245677A1 (zh) 2015-01-23 2018-08-31 Aclaris Therapeutics, Inc. 用於治疗炎症和癌症的杂环itk抑制剂
US9873690B2 (en) 2015-03-17 2018-01-23 Pfizer Inc 3-indol substituted derivatives, pharmaceutical compositions and methods for use
US10544095B2 (en) 2015-08-10 2020-01-28 Pfizer Inc. 3-indol substituted derivatives, pharmaceutical compositions and methods for use
CN110267945A (zh) * 2016-03-01 2019-09-20 诺华股份有限公司 氰基取代的吲哚化合物及其作为lsd1抑制剂的用途
AU2017269335B2 (en) * 2016-05-26 2021-07-01 Recurium Ip Holdings, Llc EGFR inhibitor compounds
US20190298715A1 (en) * 2016-09-30 2019-10-03 Novartis Ag Immune effector cell therapies with enhanced efficacy
WO2018210660A1 (en) 2017-05-15 2018-11-22 Basf Se Heteroaryl compounds as agrochemical fungicides
WO2018210658A1 (en) 2017-05-15 2018-11-22 Basf Se Heteroaryl compounds as agrochemical fungicides
WO2018210661A1 (en) 2017-05-15 2018-11-22 Basf Se Heteroaryl compounds as agrochemical fungicides
WO2018210659A1 (en) 2017-05-15 2018-11-22 Basf Se Heteroaryl compounds as agrochemical fungicides
WO2019057660A1 (en) 2017-09-25 2019-03-28 Basf Se INDOLE AND AZAINDOLE COMPOUNDS HAVING 6-CHANNEL SUBSTITUTED ARYL AND HETEROARYL CYCLES AS AGROCHEMICAL FUNGICIDES
EP3730489A1 (en) 2019-04-25 2020-10-28 Basf Se Heteroaryl compounds as agrochemical fungicides
WO2022011091A1 (en) 2020-07-09 2022-01-13 Usher Iii Initiative, Inc. Treatment of cancer, inflammatory diseases and autoimmune diseases
KR102513463B1 (ko) 2020-11-26 2023-03-29 주식회사 에스앤케이테라퓨틱스 엔도솜 톨-유사 수용체를 제어하는 신규 소분자 화합물 및 이를 이용한 자가면역질환 치료제
JP2024536858A (ja) * 2021-09-23 2024-10-08 ３エイチ ファーマシューティカルズ カンパニー リミテッド Ｆｇｆｒ阻害剤及びその使用方法
CN116332940B (zh) * 2023-02-14 2024-09-13 广西民族大学 一种7-脱氮嘌呤衍生物及其制备方法和应用
WO2024245193A1 (zh) * 2023-05-26 2024-12-05 上海艾力斯医药科技股份有限公司 杂芳环类化合物、其药物组合物及其应用

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3022A (en) * 1843-03-30 Machine for bending stibrups for paddle-wheels of steam and other
US7004A (en) * 1850-01-08 Connecting ctjttees to shafts of boeing instetjments
US3009A (en) * 1843-03-21 Lard-lamp
GB9624482D0 (en) 1995-12-18 1997-01-15 Zeneca Phaema S A Chemical compounds
WO1997030035A1 (en) 1996-02-13 1997-08-21 Zeneca Limited Quinazoline derivatives as vegf inhibitors
ES2169355T3 (es) 1996-03-05 2002-07-01 Astrazeneca Ab Derivados de 4-anilinoquinazolina.
GB9718972D0 (en) 1996-09-25 1997-11-12 Zeneca Ltd Chemical compounds
DE69728688T2 (de) * 1996-11-19 2004-08-19 Amgen Inc., Thousand Oaks Aryl und heteroaryl substituierte kondensierte pyrrole als entzündunghemmende mittel
GB9714249D0 (en) 1997-07-08 1997-09-10 Angiogene Pharm Ltd Vascular damaging agents
CA2306870A1 (en) * 1997-10-20 1999-04-29 David Michael Goldstein Bicyclic kinase inhibitors
US6187777B1 (en) * 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
GB9900334D0 (en) 1999-01-07 1999-02-24 Angiogene Pharm Ltd Tricylic vascular damaging agents
GB9900752D0 (en) 1999-01-15 1999-03-03 Angiogene Pharm Ltd Benzimidazole vascular damaging agents
DE19951360A1 (de) * 1999-10-26 2001-05-03 Aventis Pharma Gmbh Substituierte Indole
JP2001122855A (ja) * 1999-10-27 2001-05-08 Japan Tobacco Inc インドール化合物及びその医薬用途
IL152682A0 (en) 2000-05-31 2003-06-24 Astrazeneca Ab Indole derivatives with vascular damaging activity
BR0112224A (pt) 2000-07-07 2003-06-10 Angiogene Pharm Ltd Composto, composição farmacêutica, uso de um composto ou de um sal, solvato ou pró-droga farmaceuticamente aceitável do mesmo, e, processo para preparar um composto
HUP0301742A3 (en) 2000-07-07 2005-08-29 Angiogene Pharm Ltd Colchinol derivatives as angiogenesis inhibitors, process for producing them, pharmaceutical compositions containing them and their use
AUPR283801A0 (en) * 2001-02-01 2001-03-01 Australian National University, The Chemical compounds and methods
SE0202463D0 (sv) 2002-08-14 2002-08-14 Astrazeneca Ab Novel compounds
NZ539390A (en) 2002-10-09 2007-05-31 Scios Inc Azaindole derivatives as inhibitors of p38 kinase
EP1599475A2 (en) 2003-03-06 2005-11-30 Eisai Co., Ltd. Jnk inhibitors
PL1696920T3 (pl) 2003-12-19 2015-03-31 Plexxikon Inc Związki i sposoby opracowywania modulatorów Ret
GB0405055D0 (en) 2004-03-05 2004-04-07 Eisai London Res Lab Ltd JNK inhibitors
US7507826B2 (en) 2004-03-30 2009-03-24 Vertex Pharmaceuticals Incorporated Azaindoles useful as inhibitors of JAK and other protein kinases
WO2006004984A1 (en) 2004-06-30 2006-01-12 Vertex Pharmaceuticals Incorporated Azaindoles useful as inhibitors of protein kinases
US7465726B2 (en) 2004-08-02 2008-12-16 Osi Pharmaceuticals, Inc. Substituted pyrrolo[2.3-B]pyridines
WO2006112828A1 (en) 2005-04-15 2006-10-26 Scios, Inc. Azaindole derivatives as inhibitors of p38 kinase
FR2884821B1 (fr) 2005-04-26 2007-07-06 Aventis Pharma Sa Pyrrolopyridines substitues, compositions les contenant, procede de fabrication et utilisation
KR20080016659A (ko) 2005-05-20 2008-02-21 버텍스 파마슈티칼스 인코포레이티드 단백질 키나제의 억제제로서 유용한 피롤로피리딘
DK2395004T3 (en) 2005-06-22 2016-03-21 Plexxikon Inc Pyrrolo [2,3-b] pyridine derivatives as protein kinase inhibitors
KR20080026654A (ko) 2005-07-14 2008-03-25 아스텔라스세이야쿠 가부시키가이샤 헤테로시클릭 야누스 키나제 3 억제제
CN102127078A (zh) 2005-07-14 2011-07-20 安斯泰来制药株式会社 Janus激酶3的杂环类抑制剂
US8119655B2 (en) 2005-10-07 2012-02-21 Takeda Pharmaceutical Company Limited Kinase inhibitors
WO2007067537A1 (en) 2005-12-07 2007-06-14 Osi Pharmaceuticals, Inc. Pyrrolopyridine kinase inhibiting compounds
EP1962851A2 (en) 2005-12-22 2008-09-03 SmithKline Beecham Corporation Compounds
ES2408318T3 (es) 2005-12-23 2013-06-20 Glaxosmithkline Llc Inhibidores de azaindol de las cinasas Aurora
US20090306126A1 (en) 2006-05-22 2009-12-10 Astrazeneca Ab Indole Derivatives
WO2008014249A2 (en) 2006-07-24 2008-01-31 Sanofi-Aventis Improved preparations of 2 -substituted pyrrolo [2, 3-b] pyrazine ( 4, 7 -diazaindole ) compounds
GB0708141D0 (en) * 2007-04-26 2007-06-06 Syngenta Participations Ag Improvements in or relating to organic compounds

Similar Documents

Publication Publication Date Title
JP2014520767A5 (enExample)
JP2012532899A5 (enExample)
JP2012092103A5 (enExample)
HRP20200648T1 (hr) Derivati sulfamoilpirolamida i njihova uporaba kao lijekova za liječenje hepatitisa b
MX375261B (es) Compuestos aromaticos sustituidos para el tratamiento de la fibrosis pulmonar, la fibrosis hepatica, la fibrosis de la piel y la fibrosis cardiaca.
JP2011105738A5 (enExample)
JP2013532687A5 (enExample)
JP2015536947A5 (enExample)
JP2018533593A5 (enExample)
JP2012532901A5 (enExample)
AR082728A1 (es) Imidazolonilquinolinas utiles para tratar el cancer, composiciones farmaceuticas que las contienen, proceso de sintesis, intermediarios de dicha sintesis y procedimiento para prepararlos
JP2013521295A5 (enExample)
HRP20161103T1 (hr) Kemijski spojevi
JP2010095546A5 (enExample)
FI3738434T3 (fi) Välituotteita substituoitujen bentsaldehydiyhdisteiden saamiseksi ja menetelmiä niiden käyttöön kudosten hapetuksen lisäämiseksi
JP2016006118A5 (enExample)
JP2013537203A5 (enExample)
JP2012111953A5 (enExample)
JP2016505614A5 (enExample)
JP2013501047A5 (enExample)
JP2013544860A5 (enExample)
JP2011518833A5 (enExample)
JP2015517532A5 (enExample)
EP3412668A3 (en) A selective inhibitor of phosphatidylinositol 3-kinase-gamma
JP2011513410A5 (enExample)