JP2012505836A5 - - Google Patents

Download PDF

Info

Publication number
JP2012505836A5
JP2012505836A5 JP2011531305A JP2011531305A JP2012505836A5 JP 2012505836 A5 JP2012505836 A5 JP 2012505836A5 JP 2011531305 A JP2011531305 A JP 2011531305A JP 2011531305 A JP2011531305 A JP 2011531305A JP 2012505836 A5 JP2012505836 A5 JP 2012505836A5
Authority
JP
Japan
Prior art keywords
amino
benzofuran
oxadiazol
diol
propane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011531305A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012505836A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/AU2009/001371 external-priority patent/WO2010043000A1/en
Publication of JP2012505836A publication Critical patent/JP2012505836A/ja
Publication of JP2012505836A5 publication Critical patent/JP2012505836A5/ja
Pending legal-status Critical Current

Links

JP2011531305A 2008-10-17 2009-10-19 Ｓ１ｐ受容体モジュレーターおよびそれらの使用 Pending JP2012505836A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AU2008905369A AU2008905369A0 (en) 2008-10-17 S1P Receptors Modulators and Their use Thereof
AU2008905369 2008-10-17
AU2009903644A AU2009903644A0 (en) 2009-08-05 S1P Receptors Modulators and their use Thereof
AU2009903644 2009-08-05
PCT/AU2009/001371 WO2010043000A1 (en) 2008-10-17 2009-10-19 S1p receptors modulators and their use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014192502A Division JP5963823B2 (ja) 2008-10-17 2014-09-22 Ｓ１ｐ受容体モジュレーターおよびそれらの使用

Publications (2)

Publication Number Publication Date
JP2012505836A JP2012505836A (ja) 2012-03-08
JP2012505836A5 true JP2012505836A5 (OSRAM) 2013-02-07

Family

ID=42106136

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2011531305A Pending JP2012505836A (ja) 2008-10-17 2009-10-19 Ｓ１ｐ受容体モジュレーターおよびそれらの使用
JP2014192502A Active JP5963823B2 (ja) 2008-10-17 2014-09-22 Ｓ１ｐ受容体モジュレーターおよびそれらの使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2014192502A Active JP5963823B2 (ja) 2008-10-17 2014-09-22 Ｓ１ｐ受容体モジュレーターおよびそれらの使用

Country Status (9)

Country Link
US (3) US8592399B2 (OSRAM)
EP (1) EP2344484B1 (OSRAM)
JP (2) JP2012505836A (OSRAM)
CN (1) CN102186845B (OSRAM)
AU (1) AU2009304598B2 (OSRAM)
CA (1) CA2740484C (OSRAM)
ES (1) ES2590904T3 (OSRAM)
NZ (1) NZ592748A (OSRAM)
WO (1) WO2010043000A1 (OSRAM)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010043000A1 (en) 2008-10-17 2010-04-22 Akaal Pharma Pty Ltd S1p receptors modulators and their use thereof
WO2010042998A1 (en) 2008-10-17 2010-04-22 Akaal Pharma Pty Ltd S1p receptors modulators
PE20120578A1 (es) * 2009-02-10 2012-06-17 Abbott Lab Agonistas y antagonistas del receptor de s1p5, y metodos de uso de los mismos
CN103249712B (zh) * 2010-11-30 2016-03-02 艾达索高新材料无锡有限公司 用于合成可重复利用环氧树脂的化合物
EP2697195A1 (en) * 2011-04-14 2014-02-19 Allergan, Inc. Phenyl bicyclic methyl azetidine derivatives as sphingosine-1 phosphate receptors modulators
CN102993027B (zh) * 2011-09-08 2014-08-13 中化蓝天集团有限公司 4-氟-n-异丙基苯胺的定向单烷基化制备方法
JP6033791B2 (ja) 2011-12-23 2016-11-30 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 新規ｓ１ｐ受容体調整薬
EP2847177B1 (en) 2012-05-09 2017-10-11 Boehringer Ingelheim International GmbH Methods for making oxetan-3-ylmethanamines
NZ703851A (en) 2012-07-27 2017-01-27 Biogen Ma Inc Compounds that are s1p modulating agents and/or atx modulating agents
US8859598B2 (en) * 2012-10-04 2014-10-14 Allergan, Inc. 1, 2, 4-oxadiazoles azetidine derivatives as sphingosine-1 phosphate receptors modulators
WO2014063199A1 (en) * 2012-10-26 2014-05-01 Akaal Pharma Pty Ltd Organic compounds
ES2755772T3 (es) 2012-11-07 2020-04-23 Nerviano Medical Sciences Srl Pirimidinil y piridinilpirrolopiridinonas sustituidas, proceso para su preparación y su uso como inhibidores de cinasas
US8735433B1 (en) * 2012-11-14 2014-05-27 Allergan, Inc. Aryl oxadiazole derivatives as sphingosine 1-phosphate (S1P) receptor modulators
CN103304499B (zh) * 2013-06-02 2015-03-04 张远强 抗糖尿病化合物、其制备方法和用途
CN103304503B (zh) * 2013-06-02 2015-03-04 张远强 抗糖尿病化合物、其制备方法和用途
US20150051186A1 (en) * 2013-08-15 2015-02-19 Allergan, Inc. Aryl azetidine derivatives as sphingosine-1 phosphate receptors modulators
WO2015129859A1 (ja) * 2014-02-28 2015-09-03 キッセイ薬品工業株式会社 新規なアニリン誘導体、それを含有する医薬組成物およびそれらの用途
KR20170124602A (ko) 2015-03-13 2017-11-10 포르마 세라퓨틱스 인크. Hdac8 억제제로서의 알파-신나미드 화합물 및 조성물
US20180228778A1 (en) * 2015-08-11 2018-08-16 Akaal Pharma Pty Ltd Compositions comprising s1p receptor modulators
CA3013917A1 (en) 2016-02-09 2017-08-17 Pharmakea, Inc. Quinolinone lysyl oxidase-like 2 inhibitors and uses thereof
WO2018118782A2 (en) * 2016-12-20 2018-06-28 Oligomerix, Inc. Novel benzofuran, benzothiophene, and indole analogs that inhibit the formation of tau oligomers and their method of use
EP3558950B1 (en) 2016-12-20 2023-05-10 Oligomerix, Inc. Novel quinazolinones that inhibit the formation of tau oligomers and their method of use
IL271149B2 (en) 2017-06-14 2024-05-01 Trevena Inc Compounds for modulating s1p1 activity and methods of using the same
KR102017324B1 (ko) * 2018-04-30 2019-09-02 경북대학교 산학협력단 신규한 asm 활성 직접 억제 화합물 2-아미노-2-(1,2,3-트리아졸-4-일)프로판-1,3-디올 유도체 및 이의 용도
EP3863633A4 (en) 2018-10-09 2022-10-26 Duke University COMPOSITIONS AND METHODS FOR THE ADJUVANT TREATMENT OF CANCER
WO2020114477A1 (zh) * 2018-12-06 2020-06-11 上海济煜医药科技有限公司 作为免疫调节剂的化合物及其制备方法和应用
CN109824685B (zh) * 2019-04-03 2021-03-23 辽宁中医药大学 马齿苋中化合物oleracone G及其提取分离方法与应用
BR112022003959A2 (pt) * 2019-09-05 2022-05-24 Trevena Inc Métodos para tratamento de epilepsia
CN114727977A (zh) 2019-11-19 2022-07-08 特维娜有限公司 化合物和化合物s1p1调节剂的制备方法
US20230094545A1 (en) * 2020-02-28 2023-03-30 Akaal Pharma Pty Ltd S1p receptor modulators
US12036286B2 (en) 2021-03-18 2024-07-16 Seagen Inc. Selective drug release from internalized conjugates of biologically active compounds
TW202430031A (zh) 2022-09-30 2024-08-01 瑞士商先正達農作物保護股份公司 殺微生物之吡唑衍生物
TW202430514A (zh) 2022-09-30 2024-08-01 瑞士商先正達農作物保護股份公司 殺微生物之吡唑衍生物
WO2024115512A1 (en) 2022-11-30 2024-06-06 Syngenta Crop Protection Ag Microbiocidal tetrahydroisoquinoline derivatives
WO2025114167A1 (en) 2023-11-28 2025-06-05 Syngenta Crop Protection Ag Microbiocidal pyrazole derivatives
WO2025191053A1 (en) 2024-03-14 2025-09-18 Syngenta Crop Protection Ag Microbiocidal pyrazole derivatives
WO2025210096A1 (en) 2024-04-03 2025-10-09 Syngenta Crop Protection Ag Fungicidal compositions
WO2025210095A1 (en) 2024-04-03 2025-10-09 Syngenta Crop Protection Ag Microbiocidal tetrahydroisoquinoline compounds
CN118878551A (zh) * 2024-07-08 2024-11-01 安徽大学 一种4-溴噻吩并[2,3-c]吡啶-2-羧酸乙酯的制备方法

Family Cites Families (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2550646A (en) 1947-08-21 1951-04-24 Commercial Solvents Corp Polyamino alcohols and method for preparing them
DK1130017T3 (da) * 1990-11-30 2005-10-10 Otsuka Pharma Co Ltd Azolderivater og deres anvendelse som superoxidradikalinhibitorer
CA2150345A1 (en) * 1993-09-28 1995-04-06 Makoto Komatsu Quinoxaline derivative as antidiabetic agent
FR2719044B1 (fr) 1994-04-26 1996-05-31 Cird Galderma Nouveaux composés bi-aromatiques acétylénés à groupement adamantyle, compositions pharmaceutiques et cosmétiques les contenant et utilisations.
US5883106A (en) * 1994-10-18 1999-03-16 Pfizer Inc. 5-lipoxygenase inhibitors
JP3964478B2 (ja) * 1995-06-30 2007-08-22 エーザイ・アール・アンド・ディー・マネジメント株式会社 ヘテロ環含有カルボン酸誘導体及びそれを含有する医薬
US6221865B1 (en) * 1995-11-06 2001-04-24 University Of Pittsburgh Inhibitors of protein isoprenyl transferases
FR2741876B1 (fr) * 1995-12-01 1998-01-09 Cird Galderma Composes biaromatiques portant un groupement adamantyl en para, compositions pharmaceutiques et cosmetiques les contenant et utilisations
JPH10158192A (ja) 1996-10-03 1998-06-16 Eisai Co Ltd 移植片対宿主疾患（ｇｖｈｄ）の治療および臓器移植時の移植片拒絶反応抑制のための医薬組成物
US6228868B1 (en) * 1998-07-27 2001-05-08 Abbott Laboratories Oxazoline antiproliferative agents
CA2355694A1 (en) 1998-12-18 2000-06-29 Yuhko Aoki Novel bicyclic compounds
MXPA02005982A (es) 1999-12-17 2003-01-28 Abbott Lab Inhibodres de expresion del gen de interleucina 5.
JP4612990B2 (ja) * 2001-03-16 2011-01-12 アボット・ラボラトリーズ ヒスタミン−３受容体リガンドとしての新規アミンおよびそれらの治療的適用
US20040106794A1 (en) * 2001-04-16 2004-06-03 Schering Corporation 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
TW200304375A (en) * 2001-12-06 2003-10-01 Maxia Pharmaceuticals Inc 2-Substituted thiazolidinone and oxazolidinone derivatives for the inhibition of phosphatases and the treatment of cancer
WO2004047724A2 (en) 2002-05-16 2004-06-10 Genelabs Technologies, Inc Aryl and heteroaryl compounds as antibacterial and antifungal agents
AU2003301226A1 (en) 2002-12-20 2004-07-22 Pharmacia Corp Acyclic pyrazole compounds for the inhibition of mitogen activated protein kinase-activated protein kinase-2
WO2004074297A1 (ja) * 2003-02-18 2004-09-02 Kyorin Pharmaceutical Co., Ltd. アミノホスホン酸誘導体とその付加塩及びs1p受容体調節剤
ATE537825T1 (de) * 2003-05-19 2012-01-15 Irm Llc Immunosuppressive verbindungen und zusammensetzungen
ES2754221T3 (es) 2003-08-29 2020-04-16 Ono Pharmaceutical Co Compuesto capaz de unirse al receptor de S1P y uso farmacéutico del mismo
ATE396973T1 (de) 2003-10-03 2008-06-15 Merck & Co Inc Benzylether- und benzylamino-beta-sekretase- hemmer zur behandlung von alzheimer-krankheit
TW200538433A (en) * 2004-02-24 2005-12-01 Irm Llc Immunosuppressant compounds and compositiions
CN101006053A (zh) 2004-06-18 2007-07-25 比奥里波克斯公司 用于治疗炎症的吲哚
US20060223866A1 (en) * 2004-08-13 2006-10-05 Praecis Pharmaceuticals, Inc. Methods and compositions for modulating sphingosine-1-phosphate (S1P) receptor activity
WO2006022442A1 (ja) * 2004-08-24 2006-03-02 Santen Pharmaceutical Co., Ltd. ジヒドロオロテートデヒドロゲナーゼ阻害活性を有する新規複素環アミド誘導体
CA2587566A1 (en) * 2004-11-18 2006-05-26 The Institutes For Pharmaceutical Discovery, Llc Heterocyclylbiphenyl derivates as protein tyrosine phosphatase inhibitors
JP4874958B2 (ja) 2005-03-30 2012-02-15 エーザイ・アール・アンド・ディー・マネジメント株式会社 ピリジン誘導体を含有する抗真菌剤
CA2605594A1 (en) 2005-04-22 2006-11-02 Daiichi Sankyo Company, Limited Heterocyclic compound
FR2887882B1 (fr) * 2005-07-01 2007-09-07 Sanofi Aventis Sa Derives de pyrido[2,3-d] pyrimidine, leur preparation, leur application en therapeutique
RU2008110949A (ru) * 2005-08-23 2009-09-27 Айрм Ллк (Bm) Соединения и композиции-иммуносупрессанты
JP2007169194A (ja) 2005-12-21 2007-07-05 Kyorin Pharmaceut Co Ltd ジオキサフォスフォリナン誘導体とその付加塩及びスフィンゴシン−１−リン酸（ｓ１ｐ１，ｓ１ｐ４）受容体作動薬
WO2007076055A2 (en) 2005-12-22 2007-07-05 Entremed, Inc. Compositions and methods comprising proteinase activated receptor antagonists
SI1962830T1 (sl) * 2005-12-23 2013-07-31 Glaxosmithkline Llc Azaindolni inhibitorji kinaz Aurora
JP2009526073A (ja) 2006-02-09 2009-07-16 ユニバーシティ オブ バージニア パテント ファンデーション 二環式スフィンゴシン−１−リン酸受容体アナログ
AU2007236707C1 (en) * 2006-04-03 2012-05-24 Astellas Pharma Inc. Hetero compound
MX2008013583A (es) * 2006-04-26 2008-10-31 Genentech Inc Compuestos del inhibidor de fosfoinositido 3-cinasa y composiciones farmaceuticas que los contienen.
TW200823182A (en) * 2006-08-01 2008-06-01 Praecis Pharm Inc Chemical compounds
EP2056807B1 (en) 2006-08-17 2012-09-26 University Of Chicago Treatment of inflammatory diseases
JP2009269819A (ja) * 2006-08-25 2009-11-19 Asahi Kasei Pharma Kk アミン化合物
WO2008064320A2 (en) 2006-11-21 2008-05-29 University Of Virginia Patent Foundation Hydrindane analogs having sphingosine 1-phosphate receptor agonist activity
WO2008073785A2 (en) 2006-12-07 2008-06-19 Genentech, Inc. Phosphoinositide 3-kinase inhibitor compounds and methods of use
AR064155A1 (es) * 2006-12-07 2009-03-18 Piramed Ltd Compuestos de inhibidores de fosfoinositido-3 quinasa y metodos de uso
US8486979B2 (en) * 2006-12-12 2013-07-16 Abbvie Inc. 1,2,4 oxadiazole compounds and methods of use thereof
US20080167286A1 (en) 2006-12-12 2008-07-10 Abbott Laboratories Pharmaceutical compositions and their methods of use
AU2007338700A1 (en) 2006-12-21 2008-07-03 Abbott Laboratories Sphingosine-1 -phosphate receptor agonist and antagonist compounds
JP5198293B2 (ja) 2007-02-13 2013-05-15 杏林製薬株式会社 アミノアルコール誘導体を有効成分とする脱髄性疾患の治療剤又は予防剤
BRPI0807813A2 (pt) 2007-02-15 2014-08-05 Hoffmann La Roche 2-amino-oxazolinas como ligantes de taar1
EP2014653A1 (en) 2007-06-15 2009-01-14 Bioprojet Novel dicarboxylic acid derivatives as S1P1 receptor agonists
US20090118349A1 (en) * 2007-08-16 2009-05-07 Onco-Pharmakon Incorporated Bis-alkylating agents and their use in cancer therapy
US8217028B2 (en) 2008-06-20 2012-07-10 Glaxo Group Limited 1,2,4-oxadiazole indole compounds
WO2010042998A1 (en) 2008-10-17 2010-04-22 Akaal Pharma Pty Ltd S1p receptors modulators
WO2010043000A1 (en) * 2008-10-17 2010-04-22 Akaal Pharma Pty Ltd S1p receptors modulators and their use thereof
EP2370438A1 (en) * 2008-12-04 2011-10-05 Exelixis, Inc. Imidazo [1,2a]pyridine derivatives, their use as s1p1 agonists and methods for their production
EA201170828A1 (ru) 2008-12-18 2011-12-30 Мерк Сероно С.А. Конденсированные гетероциклические производные оксадиазола, подходящие для лечения рассеянного склероза
WO2014063199A1 (en) * 2012-10-26 2014-05-01 Akaal Pharma Pty Ltd Organic compounds

Similar Documents

Publication Publication Date Title
JP2012505836A5 (OSRAM)
ES2660831T3 (es) Derivados de imidazol condensados útiles como inhibidores de IDO
JP2013508279A5 (OSRAM)
JP2019526596A5 (OSRAM)
NZ592748A (en) 2-Amino-(oxadiazol-3-yl)-benzofuran derivatives and their use as S1P receptor modulators
JP2010523522A5 (OSRAM)
JP2014505107A5 (OSRAM)
JP2010138190A5 (OSRAM)
JP2012525393A5 (OSRAM)
JP2015505296A5 (OSRAM)
JP2014511892A5 (OSRAM)
JP2013545730A5 (OSRAM)
JP2009504763A5 (OSRAM)
RU2017105470A (ru) Способы лечения парамиксовирусов
JP2019520344A5 (OSRAM)
JP2017531038A5 (OSRAM)
JP2008539268A5 (OSRAM)
JP2014505096A5 (OSRAM)
JP2014500265A5 (OSRAM)
JP2015516427A5 (OSRAM)
JP2019505529A5 (OSRAM)
JP2016522254A5 (OSRAM)
JP2013508282A (ja) ウイルス感染のための併用療法処置
JP2015536974A5 (OSRAM)
RU2013130878A (ru) Гидроксилированные производные аминотриазола в качестве агонистов рецептора alx