CN102186845B - S1p受体调节剂以及它们的用途 - Google Patents
S1p受体调节剂以及它们的用途 Download PDFInfo
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- CN102186845B CN102186845B CN200980141188.9A CN200980141188A CN102186845B CN 102186845 B CN102186845 B CN 102186845B CN 200980141188 A CN200980141188 A CN 200980141188A CN 102186845 B CN102186845 B CN 102186845B
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- 0 *c1c(*)[o]c2ccccc12 Chemical compound *c1c(*)[o]c2ccccc12 0.000 description 8
- KKGQTZUTZRNORY-UHFFFAOYSA-N CCCCCCCCc1ccc(CCC(CO)(CO)N)cc1 Chemical compound CCCCCCCCc1ccc(CCC(CO)(CO)N)cc1 KKGQTZUTZRNORY-UHFFFAOYSA-N 0.000 description 1
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- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
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| EP2344446A4 (en) | 2008-10-17 | 2012-04-04 | Akaal Pharma Pty Ltd | S1P RECEPTOR MODULATORS |
| PE20120578A1 (es) * | 2009-02-10 | 2012-06-17 | Abbott Lab | Agonistas y antagonistas del receptor de s1p5, y metodos de uso de los mismos |
| JP6107660B2 (ja) * | 2010-11-30 | 2017-04-05 | 艾達索高新材料蕪湖有限公司 | 再加工可能なエポキシ樹脂のための新規薬剤 |
| CA2833305A1 (en) * | 2011-04-14 | 2012-10-18 | Allergan, Inc. | Phenyl bicyclic methyl azetidine derivatives as sphingosine-1 phosphate receptors modulators |
| CN102993027B (zh) * | 2011-09-08 | 2014-08-13 | 中化蓝天集团有限公司 | 4-氟-n-异丙基苯胺的定向单烷基化制备方法 |
| KR101889131B1 (ko) | 2011-12-23 | 2018-09-20 | 메이지 세이카 파루마 가부시키가이샤 | 신규 s1p 수용체 조정제 |
| WO2013169531A1 (en) * | 2012-05-09 | 2013-11-14 | Boehringer Ingelheim International Gmbh | Methods for making oxetan-3-ylmethanamines |
| EP2877180B1 (en) * | 2012-07-27 | 2018-01-03 | Biogen MA Inc. | Compounds that are s1p modulating agents and/or atx modulating agents |
| US8859598B2 (en) | 2012-10-04 | 2014-10-14 | Allergan, Inc. | 1, 2, 4-oxadiazoles azetidine derivatives as sphingosine-1 phosphate receptors modulators |
| WO2014063199A1 (en) * | 2012-10-26 | 2014-05-01 | Akaal Pharma Pty Ltd | Organic compounds |
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| JP2019508400A (ja) | 2016-02-09 | 2019-03-28 | ファーマケア,インク. | キノリノンリシルオキシダーゼ様2阻害剤とその使用 |
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| EP2344484A1 (en) | 2011-07-20 |
| US8592399B2 (en) | 2013-11-26 |
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| EP2344484A4 (en) | 2012-07-18 |
| US9193716B2 (en) | 2015-11-24 |
| JP2015057388A (ja) | 2015-03-26 |
| JP2012505836A (ja) | 2012-03-08 |
| CA2740484C (en) | 2021-09-21 |
| US20140066427A1 (en) | 2014-03-06 |
| CN102186845A (zh) | 2011-09-14 |
| US9707205B2 (en) | 2017-07-18 |
| EP2344484B1 (en) | 2016-06-08 |
| ES2590904T3 (es) | 2016-11-24 |
| WO2010043000A1 (en) | 2010-04-22 |
| US20160038455A1 (en) | 2016-02-11 |
| CA2740484A1 (en) | 2010-04-22 |
| NZ592748A (en) | 2013-01-25 |
| JP5963823B2 (ja) | 2016-08-03 |
| AU2009304598B2 (en) | 2015-01-29 |
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