EP0475255A3
(en)
*
|
1990-09-12 |
1993-04-14 |
F. Hoffmann-La Roche Ag |
Process for the preparation of optically pure (s)-alpha-((tert-butylsulfonyl)methyl)hydro cinnamic acid
|
PL194025B1
(pl)
|
1996-10-18 |
2007-04-30 |
Vertex Pharma |
Inhibitory proteaz serynowych, a zwłaszcza proteazy wirusa NS3 zapalenia wątroby C, kompozycja farmaceutyczna i zastosowanie inhibitorów proteaz serynowych
|
EP1003775B1
(de)
|
1997-08-11 |
2005-03-16 |
Boehringer Ingelheim (Canada) Ltd. |
Hepatitis c inhibitor peptide
|
WO1999007734A2
(en)
|
1997-08-11 |
1999-02-18 |
Boehringer Ingelheim (Canada) Ltd. |
Hepatitis c inhibitor peptide analogues
|
US6323180B1
(en)
|
1998-08-10 |
2001-11-27 |
Boehringer Ingelheim (Canada) Ltd |
Hepatitis C inhibitor tri-peptides
|
AR022061A1
(es)
|
1998-08-10 |
2002-09-04 |
Boehringer Ingelheim Ca Ltd |
Peptidos inhibidores de la hepatitis c, una composicion farmaceutica que los contiene, el uso de los mismos para preparar una composicion farmaceutica, el uso de un producto intermedio para la preparacion de estos peptidos y un procedimiento para la preparacion de un peptido analogo de los mismos.
|
UA74546C2
(en)
|
1999-04-06 |
2006-01-16 |
Boehringer Ingelheim Ca Ltd |
Macrocyclic peptides having activity relative to hepatitis c virus, a pharmaceutical composition and use of the pharmaceutical composition
|
KR100939155B1
(ko)
|
2000-07-21 |
2010-01-28 |
쉐링 코포레이션 |
C형 간염 바이러스의 ns3-세린 프로테아제 억제제로서의신규한 펩티드
|
US7244721B2
(en)
|
2000-07-21 |
2007-07-17 |
Schering Corporation |
Peptides as NS3-serine protease inhibitors of hepatitis C virus
|
EP1337550B1
(de)
|
2000-11-20 |
2006-05-24 |
Bristol-Myers Squibb Company |
Hepatitis c tripeptid inhibitoren
|
US6867185B2
(en)
|
2001-12-20 |
2005-03-15 |
Bristol-Myers Squibb Company |
Inhibitors of hepatitis C virus
|
CA2369711A1
(en)
|
2002-01-30 |
2003-07-30 |
Boehringer Ingelheim (Canada) Ltd. |
Macrocyclic peptides active against the hepatitis c virus
|
CA2369970A1
(en)
|
2002-02-01 |
2003-08-01 |
Boehringer Ingelheim (Canada) Ltd. |
Hepatitis c inhibitor tri-peptides
|
CA2370396A1
(en)
|
2002-02-01 |
2003-08-01 |
Boehringer Ingelheim (Canada) Ltd. |
Hepatitis c inhibitor tri-peptides
|
US6828301B2
(en)
|
2002-02-07 |
2004-12-07 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical compositions for hepatitis C viral protease inhibitors
|
AU2003248535A1
(en)
|
2002-05-20 |
2003-12-12 |
Bristol-Myers Squibb Company |
Heterocyclicsulfonamide hepatitis c virus inhibitors
|
WO2004043339A2
(en)
|
2002-05-20 |
2004-05-27 |
Bristol-Myers Squibb Company |
Substituted cycloalkyl p1' hepatitis c virus inhibitors
|
MY140680A
(en)
|
2002-05-20 |
2010-01-15 |
Bristol Myers Squibb Co |
Hepatitis c virus inhibitors
|
DE60336550D1
(de)
|
2002-05-20 |
2011-05-12 |
Bristol Myers Squibb Co |
Inhibitoren des hepatitis-c-virus
|
US20060199773A1
(en)
*
|
2002-05-20 |
2006-09-07 |
Sausker Justin B |
Crystalline forms of (1R,2S)-N-[(1,1-dimethylethoxy)carbonyl]-3-methyl-L-valyl-(4R)-4-[(6-methoxy-1-isoquinolinyl)oxy]-L-prolyl-1-amino-N-(cyclopropylsulfonyl)-2-ethenyl-cyclopropanecarboxamide, monopotassium salt
|
US20040033959A1
(en)
|
2002-07-19 |
2004-02-19 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Pharmaceutical compositions for hepatitis C viral protease inhibitors
|
US20050075279A1
(en)
|
2002-10-25 |
2005-04-07 |
Boehringer Ingelheim International Gmbh |
Macrocyclic peptides active against the hepatitis C virus
|
US7601709B2
(en)
*
|
2003-02-07 |
2009-10-13 |
Enanta Pharmaceuticals, Inc. |
Macrocyclic hepatitis C serine protease inhibitors
|
CA2515216A1
(en)
|
2003-02-07 |
2004-08-26 |
Enanta Pharmaceuticals, Inc. |
Macrocyclic hepatitis c serine protease inhibitors
|
CA2516018C
(en)
|
2003-03-05 |
2011-08-23 |
Boehringer Ingelheim International Gmbh |
Hepatitis c inhibitor peptide analogs
|
WO2004101605A1
(en)
|
2003-03-05 |
2004-11-25 |
Boehringer Ingelheim International Gmbh |
Hepatitis c inhibiting compounds
|
JP2006522017A
(ja)
|
2003-04-02 |
2006-09-28 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
C型肝炎ウイルスプロテアーゼインヒビターのための医薬組成物
|
ATE422895T1
(de)
|
2003-04-16 |
2009-03-15 |
Bristol Myers Squibb Co |
Makrocyclische isochinolinpeptidinhibitoren des hepatitis-c-virus
|
CA2522561C
(en)
|
2003-04-18 |
2012-07-17 |
Enanta Pharmaceuticals, Inc. |
Quinoxalinyl macrocyclic hepatitis c serine protease inhibitors
|
BRPI0410456B8
(pt)
|
2003-05-21 |
2021-05-25 |
Boehringer Ingelheim Int |
compostos inibidores de hepatite c, composição farmacêutica, uso dos mesmos, bem como artigo de fabricação
|
WO2004113365A2
(en)
|
2003-06-05 |
2004-12-29 |
Enanta Pharmaceuticals, Inc. |
Hepatitis c serine protease tri-peptide inhibitors
|
US7125845B2
(en)
|
2003-07-03 |
2006-10-24 |
Enanta Pharmaceuticals, Inc. |
Aza-peptide macrocyclic hepatitis C serine protease inhibitors
|
ATE500264T1
(de)
|
2003-09-22 |
2011-03-15 |
Boehringer Ingelheim Int |
Makrozyklische peptide mit wirkung gegen das hepatitis-c-virus
|
EP2361925A1
(de)
|
2003-10-10 |
2011-08-31 |
Vertex Pharmaceuticals Incorporated |
Inhibitoren der Serinproteasen, insbesondere der HCV-NS3-NS4A-Protease
|
WO2005037214A2
(en)
|
2003-10-14 |
2005-04-28 |
Intermune, Inc. |
Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of hcv replication
|
US7132504B2
(en)
|
2003-11-12 |
2006-11-07 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US7309708B2
(en)
|
2003-11-20 |
2007-12-18 |
Birstol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
WO2005051980A1
(en)
|
2003-11-20 |
2005-06-09 |
Schering Corporation |
Depeptidized inhibitors of hepatitis c virus ns3 protease
|
US7135462B2
(en)
|
2003-11-20 |
2006-11-14 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
JP4682155B2
(ja)
|
2004-01-21 |
2011-05-11 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
C型肝炎ウイルスに対して活性な大環状ペプチド
|
US7671032B2
(en)
|
2004-01-30 |
2010-03-02 |
Medivir Ab |
HCV NS-3 serine protease inhibitors
|
JP4654239B2
(ja)
*
|
2004-03-15 |
2011-03-16 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
C型肝炎ウィルス感染症の治療に適した大環状ジペプチドの調製方法
|
JP4950026B2
(ja)
|
2004-03-30 |
2012-06-13 |
インターミューン・インコーポレーテッド |
ウイルス複製阻害剤としての大環状化合物
|
WO2006016930A2
(en)
|
2004-05-14 |
2006-02-16 |
Intermune, Inc. |
Methods for treating hcv infection
|
CA2568008C
(en)
|
2004-05-25 |
2014-01-28 |
Boehringer Ingelheim International Gmbh |
Process for preparing acyclic hcv protease inhibitors
|
EP1763531A4
(de)
|
2004-06-28 |
2009-07-01 |
Boehringer Ingelheim Int |
Analoga von hepatitis-c inhibierenden peptiden
|
PL382845A1
(pl)
|
2004-07-16 |
2008-01-21 |
Gilead Sciences, Inc. |
Związki przeciwwirusowe
|
ES2366478T3
(es)
|
2004-07-20 |
2011-10-20 |
Boehringer Ingelheim International Gmbh |
Análogos peptídicos inhibidores de la hepatitis c.
|
UY29016A1
(es)
|
2004-07-20 |
2006-02-24 |
Boehringer Ingelheim Int |
Analogos de dipeptidos inhibidores de la hepatitis c
|
CN101068828A
(zh)
|
2004-08-27 |
2007-11-07 |
先灵公司 |
用作丙型肝炎病毒ns3丝氨酸蛋白酶抑制剂的酰基磺酰胺化合物
|
JP2008513454A
(ja)
|
2004-09-17 |
2008-05-01 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
大環状hcvプロテアーゼインヒビターの調製方法
|
WO2007001406A2
(en)
|
2004-10-05 |
2007-01-04 |
Chiron Corporation |
Aryl-containing macrocyclic compounds
|
CA2583152A1
(en)
|
2004-10-21 |
2006-04-27 |
Pfizer Inc. |
Inhibitors of hepatitis c virus protease, and compositions and treatments using the same
|
US7323447B2
(en)
|
2005-02-08 |
2008-01-29 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
KR101514953B1
(ko)
|
2005-03-08 |
2015-04-24 |
베링거 인겔하임 인터내셔날 게엠베하 |
매크로사이클릭 화합물의 제조방법
|
JP4705164B2
(ja)
|
2005-05-02 |
2011-06-22 |
メルク・シャープ・エンド・ドーム・コーポレイション |
Hcvns3プロテアーゼ阻害剤
|
US7592336B2
(en)
|
2005-05-10 |
2009-09-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
EP1891089B1
(de)
|
2005-06-02 |
2014-11-05 |
Merck Sharp & Dohme Corp. |
HCV Proteasehemmer in Kombination mit Nahrungsmitteln
|
AR055198A1
(es)
|
2005-06-02 |
2007-08-08 |
Schering Corp |
Formulaciones farmaceuticas y metodos de tratamiento que las utilizan
|
WO2006130666A2
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Medicaments and methods combining a hcv protease inhibitor and an akr competitor
|
US20060281689A1
(en)
|
2005-06-02 |
2006-12-14 |
Schering Corporation |
Method for modulating activity of HCV protease through use of a novel HCV protease inhibitor to reduce duration of treatment period
|
WO2006130688A2
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Compounds for inhibiting cathepsin activity
|
US20060276406A1
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Methods of treating hepatitis C virus
|
WO2006130553A2
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Hcv protease inhibitors
|
US20060276407A1
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Methods of treating hepatitis C virus
|
US20070021351A1
(en)
|
2005-06-02 |
2007-01-25 |
Schering Corporation |
Liver/plasma concentration ratio for dosing hepatitis C virus protease inhibitor
|
WO2006130627A2
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Methods for treating hepatitis c
|
JP2008545748A
(ja)
|
2005-06-02 |
2008-12-18 |
シェーリング コーポレイション |
C型肝炎ウイルスに関連する障害を処置するために有用な徐放処方物
|
US7601686B2
(en)
|
2005-07-11 |
2009-10-13 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
TW200738742A
(en)
*
|
2005-07-14 |
2007-10-16 |
Gilead Sciences Inc |
Antiviral compounds
|
TWI389908B
(zh)
|
2005-07-14 |
2013-03-21 |
Gilead Sciences Inc |
抗病毒化合物類
|
WO2007009227A1
(en)
|
2005-07-20 |
2007-01-25 |
Boehringer Ingelheim International Gmbh |
Hepatitis c inhibitor peptide analogs
|
AR057456A1
(es)
|
2005-07-20 |
2007-12-05 |
Merck & Co Inc |
Inhibidores de la proteasa ns3 del vhc
|
MX2008001166A
(es)
|
2005-07-25 |
2008-03-18 |
Intermune Inc |
Nuevos inhibidores macrociclicos de la replicacion del virus de hepatitis c.
|
JP5230416B2
(ja)
|
2005-07-29 |
2013-07-10 |
テイボテク・フアーマシユーチカルズ |
C型肝炎ウイルスの大員環状阻害剤
|
EP1919899B1
(de)
|
2005-07-29 |
2011-01-19 |
Tibotec Pharmaceuticals |
Makrocyclische inhibitoren des hepatitis-c-virus
|
RU2441870C2
(ru)
|
2005-07-29 |
2012-02-10 |
Тиботек Фармасьютикалз Лтд. |
Макроциклические ингибиторы вируса гепатита с
|
PE20070210A1
(es)
|
2005-07-29 |
2007-04-16 |
Tibotec Pharm Ltd |
Compuestos macrociclicos como inhibidores del virus de hepatitis c
|
US8012939B2
(en)
|
2005-07-29 |
2011-09-06 |
Tibotec Pharmaceuticals Ltd. Co |
Macrocyclic inhibitors of hepatitis C virus
|
PE20070343A1
(es)
|
2005-07-29 |
2007-05-12 |
Medivir Ab |
Inhibidores macrociclicos del virus de la hepatitis c
|
SI1919898T1
(sl)
|
2005-07-29 |
2011-05-31 |
Tibotec Pharm Ltd |
Makrociklični inhibitorji virusa hepatitisa C
|
CN101273038A
(zh)
|
2005-07-29 |
2008-09-24 |
美迪维尔公司 |
丙型肝炎病毒的大环化合物抑制剂
|
PE20070211A1
(es)
|
2005-07-29 |
2007-05-12 |
Medivir Ab |
Compuestos macrociclicos como inhibidores del virus de hepatitis c
|
ATE524475T1
(de)
|
2005-07-29 |
2011-09-15 |
Tibotec Pharm Ltd |
Makrocyclische inhibitoren des hepatitis-c-virus
|
JO2768B1
(en)
|
2005-07-29 |
2014-03-15 |
تيبوتيك فارماسيوتيكالز ليمتد |
Large cyclic inhibitors of hepatitis C virus
|
JP2009503084A
(ja)
|
2005-08-01 |
2009-01-29 |
フェノミックス コーポレーション |
C型肝炎セリンプロテアーゼ阻害剤およびその使用
|
MX2008001588A
(es)
|
2005-08-01 |
2008-02-19 |
Merck & Co Inc |
Inhibidores de proteasa ns3 del vhc.
|
AR055395A1
(es)
|
2005-08-26 |
2007-08-22 |
Vertex Pharma |
Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c
|
EA200801050A1
(ru)
|
2005-10-11 |
2008-12-30 |
Интермьюн, Инк. |
Соединения и способы ингибирования репликации вирусного гепатита с
|
US7772183B2
(en)
|
2005-10-12 |
2010-08-10 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US8268776B2
(en)
*
|
2006-06-06 |
2012-09-18 |
Enanta Pharmaceuticals, Inc. |
Macrocylic oximyl hepatitis C protease inhibitors
|
GB0612423D0
(en)
*
|
2006-06-23 |
2006-08-02 |
Angeletti P Ist Richerche Bio |
Therapeutic agents
|
US7635683B2
(en)
*
|
2006-08-04 |
2009-12-22 |
Enanta Pharmaceuticals, Inc. |
Quinoxalinyl tripeptide hepatitis C virus inhibitors
|
US7605126B2
(en)
*
|
2006-08-11 |
2009-10-20 |
Enanta Pharmaceuticals, Inc. |
Acylaminoheteroaryl hepatitis C virus protease inhibitors
|
US7582605B2
(en)
*
|
2006-08-11 |
2009-09-01 |
Enanta Pharmaceuticals, Inc. |
Phosphorus-containing hepatitis C serine protease inhibitors
|
US8309540B2
(en)
*
|
2006-10-24 |
2012-11-13 |
Merck Sharp & Dohme Corp. |
HCV NS3 protease inhibitors
|
CA2667031C
(en)
*
|
2006-10-27 |
2013-01-22 |
Merck & Co., Inc. |
Hcv ns3 protease inhibitors
|
US7888464B2
(en)
*
|
2006-11-16 |
2011-02-15 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US20080279821A1
(en)
*
|
2007-04-26 |
2008-11-13 |
Deqiang Niu |
Arylpiperidinyl and arylpyrrolidinyl macrocyclic hepatitis c serine protease inhibitors
|
CN102015652A
(zh)
*
|
2008-03-20 |
2011-04-13 |
益安药业 |
作为丙型肝炎病毒抑制剂的氟化大环化合物
|
US7964560B2
(en)
*
|
2008-05-29 |
2011-06-21 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US20100080770A1
(en)
*
|
2008-09-29 |
2010-04-01 |
Bristol-Myers Squibb Company |
Hepatitis C Virus Inhibitors
|