JP2012019797A5 - - Google Patents
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- Publication number
- JP2012019797A5 JP2012019797A5 JP2011215672A JP2011215672A JP2012019797A5 JP 2012019797 A5 JP2012019797 A5 JP 2012019797A5 JP 2011215672 A JP2011215672 A JP 2011215672A JP 2011215672 A JP2011215672 A JP 2011215672A JP 2012019797 A5 JP2012019797 A5 JP 2012019797A5
- Authority
- JP
- Japan
- Prior art keywords
- probe
- detection
- capture
- nucleic acid
- target nucleic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000523 sample Substances 0.000 claims 137
- 238000001514 detection method Methods 0.000 claims 102
- 102000039446 nucleic acids Human genes 0.000 claims 65
- 108020004707 nucleic acids Proteins 0.000 claims 65
- 150000007523 nucleic acids Chemical class 0.000 claims 65
- 239000003446 ligand Substances 0.000 claims 37
- 102000004169 proteins and genes Human genes 0.000 claims 34
- 108090000623 proteins and genes Proteins 0.000 claims 34
- 125000006850 spacer group Chemical group 0.000 claims 29
- 239000002773 nucleotide Substances 0.000 claims 15
- 125000003729 nucleotide group Chemical group 0.000 claims 15
- 239000012488 sample solution Substances 0.000 claims 12
- 238000004587 chromatography analysis Methods 0.000 claims 8
- 238000000034 method Methods 0.000 claims 7
- 238000012360 testing method Methods 0.000 claims 7
- 239000011324 bead Substances 0.000 claims 4
- 239000007790 solid phase Substances 0.000 claims 3
- HYCSHFLKPSMPGO-UHFFFAOYSA-N 3-hydroxypropyl dihydrogen phosphate Chemical compound OCCCOP(O)(O)=O HYCSHFLKPSMPGO-UHFFFAOYSA-N 0.000 claims 2
- 229910019142 PO4 Inorganic materials 0.000 claims 2
- 102000009843 Thyroglobulin Human genes 0.000 claims 2
- 108010034949 Thyroglobulin Proteins 0.000 claims 2
- PTMCGHPIYOSATH-UHFFFAOYSA-N hexaethylene glycol monophosphate Chemical compound OCCOCCOCCOCCOCCOCCOP(O)(O)=O PTMCGHPIYOSATH-UHFFFAOYSA-N 0.000 claims 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 230000003100 immobilizing effect Effects 0.000 claims 2
- 230000003993 interaction Effects 0.000 claims 2
- 239000012528 membrane Substances 0.000 claims 2
- 239000010452 phosphate Substances 0.000 claims 2
- SXADIBFZNXBEGI-UHFFFAOYSA-N phosphoramidous acid Chemical group NP(O)O SXADIBFZNXBEGI-UHFFFAOYSA-N 0.000 claims 2
- 229960002175 thyroglobulin Drugs 0.000 claims 2
- 239000000020 Nitrocellulose Substances 0.000 claims 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
- -1 for example Proteins 0.000 claims 1
- 238000002372 labelling Methods 0.000 claims 1
- 229920001220 nitrocellulos Polymers 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0016836.9 | 2000-07-07 | ||
| GBGB0016836.9A GB0016836D0 (en) | 2000-07-07 | 2000-07-07 | Improved dipstick assays (1) |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002509524A Division JP5341291B2 (ja) | 2000-07-07 | 2001-07-06 | ディップスティック検定における改良型結合相互作用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012019797A JP2012019797A (ja) | 2012-02-02 |
| JP2012019797A5 true JP2012019797A5 (enExample) | 2012-12-13 |
Family
ID=9895306
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002509524A Expired - Lifetime JP5341291B2 (ja) | 2000-07-07 | 2001-07-06 | ディップスティック検定における改良型結合相互作用 |
| JP2011215672A Withdrawn JP2012019797A (ja) | 2000-07-07 | 2011-09-29 | ディップスティック検定における改良型結合相互作用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002509524A Expired - Lifetime JP5341291B2 (ja) | 2000-07-07 | 2001-07-06 | ディップスティック検定における改良型結合相互作用 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US8431336B2 (enExample) |
| EP (1) | EP1325151B1 (enExample) |
| JP (2) | JP5341291B2 (enExample) |
| CN (2) | CN101230393A (enExample) |
| AT (1) | ATE521714T1 (enExample) |
| AU (2) | AU6928501A (enExample) |
| ES (1) | ES2372477T3 (enExample) |
| GB (1) | GB0016836D0 (enExample) |
| WO (1) | WO2002004671A2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0016813D0 (en) * | 2000-07-07 | 2000-08-30 | Lee Helen | Improved dipstick assays (4) |
| GB0016836D0 (en) | 2000-07-07 | 2000-08-30 | Lee Helen | Improved dipstick assays (1) |
| GB0025245D0 (en) | 2000-10-14 | 2000-11-29 | Lee Helen | Multiple target detection |
| DE10154291B4 (de) * | 2001-11-05 | 2005-05-19 | Hain Lifescience Gmbh | Verfahren zum Nachweis von Nukleinsäuren in Form eines Trockenschnelltestes |
| US8669052B2 (en) * | 2008-06-10 | 2014-03-11 | Rapid Pathogen Screening, Inc. | Lateral flow nucleic acid detector |
| GB0701253D0 (en) | 2007-01-23 | 2007-02-28 | Diagnostics For The Real World | Nucleic acid amplification and testing |
| US20110086359A1 (en) | 2008-06-10 | 2011-04-14 | Rapid Pathogen Screening, Inc. | Lateral flow assays |
| JP2012503170A (ja) * | 2008-07-15 | 2012-02-02 | ラピッド パトゲン スクリーニング，インク． | 側方流動イムノアッセイにおけるインサイツでの細胞の溶解 |
| CA2764315A1 (en) * | 2009-06-02 | 2010-12-09 | Monoquant Pty Ltd | A method of nucleic acid amplification |
| SG190377A1 (en) | 2010-11-24 | 2013-06-28 | Kaneka Corp | Amplified nucleic acid detection method and detection device |
| JP2013198482A (ja) * | 2012-02-22 | 2013-10-03 | Nippon Meat Packers Inc | 核酸の検出方法 |
| WO2014007289A1 (ja) * | 2012-07-05 | 2014-01-09 | 日本碍子株式会社 | 核酸クロマトグラフィー法、核酸クロマトグラフィー用組成物及びこれを含むキット |
| EP2986359B1 (en) | 2014-03-11 | 2024-08-14 | Bio-Rad Laboratories, Inc. | Dip-stick western blot |
| JP6734011B2 (ja) * | 2014-06-06 | 2020-08-05 | 古河電気工業株式会社 | 生体分子検出用試験キット、及びこれを用いた生体分子の検出方法、並びにこれらに用いられる生体分子検出用試験片及び生体分子検出用標識試薬 |
| CN108026581A (zh) | 2015-06-19 | 2018-05-11 | 剑桥企业有限公司 | 感染性疾病的诊断与治疗 |
| WO2018180987A1 (ja) * | 2017-03-29 | 2018-10-04 | 東洋紡株式会社 | 核酸の検出方法 |
| US20220348606A1 (en) * | 2019-06-26 | 2022-11-03 | Nanjing GenScript Biotech Co., Ltd. | Oligonucleotide containing blocker |
| MX2020006374A (es) * | 2020-07-13 | 2022-01-14 | Univ Mexico Nac Autonoma | Metodo de hibridacion para la deteccion de acidos nucleicos empleando particulas magneticas funcionalizadas. |
Family Cites Families (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1223222A (en) * | 1984-02-22 | 1987-06-23 | Nanibhushan Dattagupta | Immobilized nucleic acid-containing probes |
| CA1253777A (en) * | 1984-06-01 | 1989-05-09 | Robert J. Carrico | Nucleic acid hybridization assay employing immobilized rna probes |
| ATE40572T1 (de) * | 1985-01-10 | 1989-02-15 | Molecular Diagnostics Inc | Photochemisches verfahren zum markieren von nucleinsaeuren zum nachweis in hybridisationsproben. |
| GB8509367D0 (en) | 1985-04-12 | 1985-05-15 | Amersham Int Plc | Nucleic acid hybridisation |
| US4751177A (en) * | 1985-06-13 | 1988-06-14 | Amgen | Methods and kits for performing nucleic acid hybridization assays |
| US4868105A (en) * | 1985-12-11 | 1989-09-19 | Chiron Corporation | Solution phase nucleic acid sandwich assay |
| US4822731A (en) * | 1986-01-09 | 1989-04-18 | Cetus Corporation | Process for labeling single-stranded nucleic acids and hybridizaiton probes |
| US5317098A (en) * | 1986-03-17 | 1994-05-31 | Hiroaki Shizuya | Non-radioisotope tagging of fragments |
| US5310650A (en) * | 1986-09-29 | 1994-05-10 | Abbott Laboratoires | Method and device for improved reaction kinetics in nucleic acid hybridizations |
| US5283174A (en) * | 1987-09-21 | 1994-02-01 | Gen-Probe, Incorporated | Homogenous protection assay |
| WO1989004375A1 (en) | 1987-10-23 | 1989-05-18 | Siska Diagnostics, Inc. | Lanthanide chelate-tagged nucleic acid probes |
| WO1990001564A1 (en) * | 1988-08-09 | 1990-02-22 | Microprobe Corporation | Methods for multiple target analyses through nucleic acid hybridization |
| GB8822228D0 (en) * | 1988-09-21 | 1988-10-26 | Southern E M | Support-bound oligonucleotides |
| DE3842700A1 (de) * | 1988-12-19 | 1990-06-21 | Boehringer Mannheim Gmbh | Verfahren zur proteinimmobilisierung an einer festphase, so hergestellte protein tragende festphase sowie deren verwendung |
| DE69031318D1 (de) | 1989-03-17 | 1997-10-02 | Abbott Lab | Verfahren und Vorrichtung zur Hybridisierung von Nukleinsäure mit verbesserter Reaktionskinetik |
| DE69032847T2 (de) * | 1989-06-30 | 1999-05-12 | Chiron Corp., Emeryville, Calif. | Hydrophobe Nukleinsäure-Sonde |
| US5232829A (en) | 1989-09-29 | 1993-08-03 | Hoffmann-La Roche Inc. | Detection of chlamydia trachomatis by polymerase chain reaction using biotin labelled lina primers and capture probes |
| WO1991008307A1 (en) | 1989-12-04 | 1991-06-13 | Microprobe Corporation | Enhanced capture of target nucleic acid by the use of oligonucleotides covalently attached to polymers |
| CA2031659A1 (en) * | 1990-01-26 | 1991-07-27 | John B. Findlay | Water-insoluble reagent, nucleic acid probe, test kit and diagnostic and purification methods |
| US5695926A (en) * | 1990-06-11 | 1997-12-09 | Bio Merieux | Sandwich hybridization assays using very short capture probes noncovalently bound to a hydrophobic support |
| FR2663040B1 (fr) * | 1990-06-11 | 1995-09-15 | Bio Merieux | Procede de detection d'une sequence nucleotidique selon la technique d'hybridation sandwich. |
| US5210015A (en) * | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| US5663318A (en) * | 1991-03-01 | 1997-09-02 | Pegg; Randall Kevin | Assay preparation containing capture and detection polynucleotides covalently bound to substrates with a heterobifunctional crosslinking agent |
| US5976789A (en) * | 1991-07-17 | 1999-11-02 | Bio Merieux | System of probes enabling HLA-DR typing to be performed, and typing method using said probes |
| FR2679252B1 (fr) * | 1991-07-17 | 1993-12-10 | Bio Merieux | Systeme de sondes permettant d'effectuer le typage hla dr, et procede de typage utilisant lesdites sondes. |
| FR2679255B1 (fr) * | 1991-07-17 | 1993-10-22 | Bio Merieux | Procede d'immobilisation d'un fragment nucleique par fixation passive sur un support solide, support solide ainsi obtenu et son utilisation. |
| US5747244A (en) | 1991-12-23 | 1998-05-05 | Chiron Corporation | Nucleic acid probes immobilized on polystyrene surfaces |
| WO1994000600A1 (en) | 1992-06-25 | 1994-01-06 | Microprobe Corporation | Solid supports for nucleic acid hybridization assays |
| WO1994002634A1 (en) * | 1992-07-24 | 1994-02-03 | University Of South Australia | Amplification and detection process |
| US5438131A (en) | 1992-09-16 | 1995-08-01 | Bergstrom; Donald E. | 3-nitropyrrole nucleoside |
| AU4925993A (en) | 1992-09-18 | 1994-04-12 | Abbott Laboratories | Multiple assay test strip devices |
| ES2133529T3 (es) | 1992-11-27 | 1999-09-16 | Innogenetics Nv | Procedimiento para tipificar aislamientos de hcv. |
| WO1994023299A1 (en) | 1993-03-31 | 1994-10-13 | Quidel Corporation | Multiple assay device |
| US5496934A (en) * | 1993-04-14 | 1996-03-05 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Nucleic acids encoding a cellulose binding domain |
| EP0705426A4 (en) | 1993-06-09 | 1998-07-08 | Quidel Corp | SPECIFIC ONE-STEP TITRATIONS OF AN ANTIGEN |
| US5635602A (en) * | 1993-08-13 | 1997-06-03 | The Regents Of The University Of California | Design and synthesis of bispecific DNA-antibody conjugates |
| EP0669928A1 (en) | 1993-08-18 | 1995-09-06 | Chromagen, Inc. | Applications of fluorescent n-nucleosides and fluorescent structural analogs of n-nucleosides |
| US5789167A (en) * | 1993-09-10 | 1998-08-04 | Genevue, Inc. | Optical detection of position of oligonucleotides on large DNA molecules |
| US5925517A (en) * | 1993-11-12 | 1999-07-20 | The Public Health Research Institute Of The City Of New York, Inc. | Detectably labeled dual conformation oligonucleotide probes, assays and kits |
| US5681697A (en) * | 1993-12-08 | 1997-10-28 | Chiron Corporation | Solution phase nucleic acid sandwich assays having reduced background noise and kits therefor |
| DE4406524A1 (de) * | 1994-02-28 | 1995-08-31 | Boehringer Mannheim Gmbh | 3'-RNA-Markierung mit Terminaler Transferase |
| WO1995027081A1 (en) * | 1994-03-31 | 1995-10-12 | E.I. Du Pont De Nemours And Company | A method for detection of nucleic acid fragments |
| US5747248A (en) * | 1994-12-05 | 1998-05-05 | Chiron Corporation | Discontinuous probe design using hybritope mapping |
| DE69629403T2 (de) | 1995-05-09 | 2004-06-24 | Kreatech Biotechnology B.V. | Verfahren zur herstellung von linkern zwischen markierungsgruppen und bio-organischen molekülen auf der basis von platin für die markierung von bio-organischen molekülen zur entdeckung interessanter biologischer substanzen |
| DE19537952A1 (de) * | 1995-10-12 | 1997-04-17 | Boehringer Mannheim Gmbh | Verfahren zum Nachweis eines Analyten |
| US5874216A (en) * | 1996-02-23 | 1999-02-23 | Ensys Environmental Products, Inc. | Indirect label assay device for detecting small molecules and method of use thereof |
| AU726692B2 (en) | 1996-10-08 | 2000-11-16 | Leica Biosystems Newcastle Ltd | Methods for labeling nucleotides, labeled nucleotides and useful intermediates |
| EP1068356B8 (en) * | 1998-04-03 | 2007-01-03 | Adnexus Therapeutics, Inc. | Addressable protein arrays |
| US20020012913A1 (en) * | 1998-09-15 | 2002-01-31 | Kevin L. Gunderson | Nucleic acid analysis using complete n-mer arrays |
| KR20010101092A (ko) | 1998-12-10 | 2001-11-14 | 오미야 히사시 | 운반체상에 ｄｎａ를 고정화시키는 방법 |
| DE19901761A1 (de) | 1999-01-18 | 1999-07-01 | Gerhard Dr Hartwich | Verfahren zur elektrochemischen Detektion von Nukleinsäure-Oligomer-Hybridisierungsereignissen |
| DE19910761A1 (de) * | 1999-03-11 | 2000-09-14 | Tellmann Wilfried | Magnetmotor |
| AU4058100A (en) | 1999-04-09 | 2000-11-14 | Arcturus Engineering, Inc. | Generic cdna or protein array for customized assays |
| GB0016814D0 (en) | 2000-07-07 | 2000-08-30 | Lee Helen | Improved dipstick assays (3) |
| GB0016836D0 (en) | 2000-07-07 | 2000-08-30 | Lee Helen | Improved dipstick assays (1) |
| GB0016833D0 (en) | 2000-07-07 | 2000-08-30 | Lee Helen | Improved dipstick assays (2) |
| GB0025245D0 (en) | 2000-10-14 | 2000-11-29 | Lee Helen | Multiple target detection |
| GB0029154D0 (en) | 2000-11-30 | 2001-01-17 | Lee Helen | Signal enhancement with multiple labelled-antibodies |
| GB0130947D0 (en) | 2001-12-24 | 2002-02-13 | Lee Helen | Improved sample preparation for the detection of infectious agents |
| GB0217390D0 (en) | 2002-07-26 | 2002-09-04 | Lee Helen | Liquid sampler and method |
-
2000
- 2000-07-07 GB GBGB0016836.9A patent/GB0016836D0/en not_active Ceased
-
2001
- 2001-07-06 WO PCT/GB2001/003039 patent/WO2002004671A2/en not_active Ceased
- 2001-07-06 EP EP01947639A patent/EP1325151B1/en not_active Expired - Lifetime
- 2001-07-06 US US10/332,142 patent/US8431336B2/en not_active Expired - Fee Related
- 2001-07-06 AU AU6928501A patent/AU6928501A/xx active Pending
- 2001-07-06 ES ES01947639T patent/ES2372477T3/es not_active Expired - Lifetime
- 2001-07-06 AT AT01947639T patent/ATE521714T1/de not_active IP Right Cessation
- 2001-07-06 AU AU2001269285A patent/AU2001269285B2/en not_active Expired
- 2001-07-06 CN CNA2007101849913A patent/CN101230393A/zh active Pending
- 2001-07-06 JP JP2002509524A patent/JP5341291B2/ja not_active Expired - Lifetime
- 2001-07-06 CN CNB018153097A patent/CN100355905C/zh not_active Expired - Lifetime
-
2011
- 2011-09-29 JP JP2011215672A patent/JP2012019797A/ja not_active Withdrawn
-
2013
- 2013-04-19 US US13/866,891 patent/US20140106347A1/en not_active Abandoned
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