|
US8835358B2
(en)
|
2009-12-15 |
2014-09-16 |
Cellular Research, Inc. |
Digital counting of individual molecules by stochastic attachment of diverse labels
|
|
US20190300945A1
(en)
|
2010-04-05 |
2019-10-03 |
Prognosys Biosciences, Inc. |
Spatially Encoded Biological Assays
|
|
US9371598B2
(en)
|
2010-04-05 |
2016-06-21 |
Prognosys Biosciences, Inc. |
Spatially encoded biological assays
|
|
US10787701B2
(en)
|
2010-04-05 |
2020-09-29 |
Prognosys Biosciences, Inc. |
Spatially encoded biological assays
|
|
WO2013130674A1
(en)
|
2012-02-27 |
2013-09-06 |
Cellular Research, Inc. |
Compositions and kits for molecular counting
|
|
US10400280B2
(en)
|
2012-08-14 |
2019-09-03 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
US9951386B2
(en)
|
2014-06-26 |
2018-04-24 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
US9701998B2
(en)
|
2012-12-14 |
2017-07-11 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
US10323279B2
(en)
|
2012-08-14 |
2019-06-18 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
EP3901273A1
(en)
|
2012-08-14 |
2021-10-27 |
10X Genomics, Inc. |
Microcapsule compositions and methods
|
|
US10273541B2
(en)
|
2012-08-14 |
2019-04-30 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
US11591637B2
(en)
|
2012-08-14 |
2023-02-28 |
10X Genomics, Inc. |
Compositions and methods for sample processing
|
|
US10752949B2
(en)
|
2012-08-14 |
2020-08-25 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
USRE50065E1
(en)
|
2012-10-17 |
2024-07-30 |
10X Genomics Sweden Ab |
Methods and product for optimising localised or spatial detection of gene expression in a tissue sample
|
|
WO2014093676A1
(en)
|
2012-12-14 |
2014-06-19 |
10X Technologies, Inc. |
Methods and systems for processing polynucleotides
|
|
US10533221B2
(en)
|
2012-12-14 |
2020-01-14 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
DK2954065T3
(da)
|
2013-02-08 |
2021-09-06 |
10X Genomics Inc |
Opdeling og bearbejdning af analytter og andre arter
|
|
CN105611914B
(zh)
|
2013-06-19 |
2020-09-08 |
加利福尼亚大学董事会 |
局部递送治疗剂的化学构造物
|
|
CN111500680B
(zh)
|
2013-06-25 |
2024-04-16 |
普罗格诺西斯生物科学公司 |
检测样品中生物靶标的空间分布的方法和系统
|
|
ES2711168T3
(es)
|
2013-08-28 |
2019-04-30 |
Becton Dickinson Co |
Análisis masivo en paralelo de células individuales
|
|
EP3116525B1
(en)
|
2014-03-14 |
2021-06-23 |
The Regents of the University of California |
Tco conjugates and methods for delivery of therapeutic agents
|
|
BR112016023625A2
(pt)
|
2014-04-10 |
2018-06-26 |
10X Genomics, Inc. |
dispositivos fluídicos, sistemas e métodos para encapsular e particionar reagentes, e aplicações dos mesmos
|
|
US9909167B2
(en)
|
2014-06-23 |
2018-03-06 |
The Board Of Trustees Of The Leland Stanford Junior University |
On-slide staining by primer extension
|
|
AU2015279548B2
(en)
|
2014-06-26 |
2020-02-27 |
10X Genomics, Inc. |
Methods of analyzing nucleic acids from individual cells or cell populations
|
|
MX2016016904A
(es)
|
2014-06-26 |
2017-03-27 |
10X Genomics Inc |
Analisis de secuencias de acidos nucleicos.
|
|
US12312640B2
(en)
|
2014-06-26 |
2025-05-27 |
10X Genomics, Inc. |
Analysis of nucleic acid sequences
|
|
SG11201705615UA
(en)
|
2015-01-12 |
2017-08-30 |
10X Genomics Inc |
Processes and systems for preparing nucleic acid sequencing libraries and libraries prepared using same
|
|
US10697000B2
(en)
|
2015-02-24 |
2020-06-30 |
10X Genomics, Inc. |
Partition processing methods and systems
|
|
EP3262192B1
(en)
|
2015-02-27 |
2020-09-16 |
Becton, Dickinson and Company |
Spatially addressable molecular barcoding
|
|
CN107406888A
(zh)
|
2015-03-30 |
2017-11-28 |
赛卢拉研究公司 |
用于组合条形编码的方法和组合物
|
|
US10774374B2
(en)
|
2015-04-10 |
2020-09-15 |
Spatial Transcriptomics AB and Illumina, Inc. |
Spatially distinguished, multiplex nucleic acid analysis of biological specimens
|
|
US11390914B2
(en)
|
2015-04-23 |
2022-07-19 |
Becton, Dickinson And Company |
Methods and compositions for whole transcriptome amplification
|
|
US10640816B2
(en)
*
|
2015-07-17 |
2020-05-05 |
Nanostring Technologies, Inc. |
Simultaneous quantification of gene expression in a user-defined region of a cross-sectioned tissue
|
|
EP3325649B1
(en)
|
2015-07-17 |
2024-01-03 |
Nanostring Technologies, Inc. |
Simultaneous quantification of a plurality of proteins in a user-defined region of a cross-sectioned tissue
|
|
US10828373B2
(en)
|
2015-09-10 |
2020-11-10 |
Tambo, Inc. |
Bioorthogonal compositions
|
|
WO2017044574A1
(en)
|
2015-09-11 |
2017-03-16 |
Cellular Research, Inc. |
Methods and compositions for nucleic acid library normalization
|
|
US11371094B2
(en)
|
2015-11-19 |
2022-06-28 |
10X Genomics, Inc. |
Systems and methods for nucleic acid processing using degenerate nucleotides
|
|
EP3384048B1
(en)
|
2015-12-04 |
2021-03-24 |
10X Genomics, Inc. |
Methods and compositions for nucleic acid analysis
|
|
JP6920334B2
(ja)
*
|
2016-03-25 |
2021-08-18 |
ザ ジェネラル ホスピタル コーポレイション |
偏光に基づく蛍光核酸検出
|
|
US10301677B2
(en)
|
2016-05-25 |
2019-05-28 |
Cellular Research, Inc. |
Normalization of nucleic acid libraries
|
|
US10202641B2
(en)
|
2016-05-31 |
2019-02-12 |
Cellular Research, Inc. |
Error correction in amplification of samples
|
|
US10640763B2
(en)
|
2016-05-31 |
2020-05-05 |
Cellular Research, Inc. |
Molecular indexing of internal sequences
|
|
WO2018004309A1
(ko)
*
|
2016-06-30 |
2018-01-04 |
김성천 |
이중가닥 핵산 신호 프로브 및 이를 이용한 표적분자의 검출방법
|
|
CN110100010B
(zh)
*
|
2016-07-18 |
2024-03-08 |
耶鲁大学 |
单细胞中细胞内或表面分子靶标的多重检测
|
|
EP4641166A3
(en)
*
|
2016-07-27 |
2025-11-19 |
The Board of Trustees of the Leland Stanford Junior University |
Highly-multiplexed fluorescent imaging
|
|
IL265478B2
(en)
*
|
2016-09-26 |
2024-10-01 |
Becton Dickinson Co |
Measurement of protein expression using reagents with barcoded oligonucleotide sequences
|
|
ES2870639T3
(es)
|
2016-10-24 |
2021-10-27 |
Geneinfosec Inc |
Ocultación de información presente en los ácidos nucleicos
|
|
CN110121364A
(zh)
*
|
2016-12-19 |
2019-08-13 |
文塔纳医疗系统公司 |
肽核酸缀合物
|
|
US10550429B2
(en)
|
2016-12-22 |
2020-02-04 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
US10815525B2
(en)
|
2016-12-22 |
2020-10-27 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
US10011872B1
(en)
|
2016-12-22 |
2018-07-03 |
10X Genomics, Inc. |
Methods and systems for processing polynucleotides
|
|
EP4310183B1
(en)
|
2017-01-30 |
2025-07-09 |
10X Genomics, Inc. |
Methods and systems for droplet-based single cell barcoding
|
|
WO2018144240A1
(en)
|
2017-02-01 |
2018-08-09 |
Cellular Research, Inc. |
Selective amplification using blocking oligonucleotides
|
|
US10995333B2
(en)
|
2017-02-06 |
2021-05-04 |
10X Genomics, Inc. |
Systems and methods for nucleic acid preparation
|
|
CN110520541B
(zh)
|
2017-02-13 |
2024-03-26 |
耶鲁大学 |
高通量单细胞多组学
|
|
AU2018250312C1
(en)
|
2017-04-07 |
2024-08-22 |
Tambo, Inc. |
Bioorthogonal compositions
|
|
EP3620529A4
(en)
*
|
2017-05-02 |
2021-02-24 |
The University of Tokyo |
METHOD FOR MONITORING DYNAMIC CHANGES IN CELLS OR SUBSTANCES DERIVED FROM CELLS AND METHODS FOR CLASSIFYING THE CELL THEREOF
|
|
US10844372B2
(en)
|
2017-05-26 |
2020-11-24 |
10X Genomics, Inc. |
Single cell analysis of transposase accessible chromatin
|
|
CN109526228B
(zh)
|
2017-05-26 |
2022-11-25 |
10X基因组学有限公司 |
转座酶可接近性染色质的单细胞分析
|
|
CN110719959B
(zh)
|
2017-06-05 |
2021-08-06 |
贝克顿迪金森公司 |
针对单细胞的样品索引
|
|
JP7361700B2
(ja)
|
2017-09-25 |
2023-10-16 |
プレキシウム インコーポレイテッド |
オリゴヌクレオチドにコードされた化学ライブラリ
|
|
US20200256862A1
(en)
*
|
2017-10-23 |
2020-08-13 |
Massachusetts Institute Of Technology |
Functionalized solid support
|
|
SG11201913654QA
(en)
|
2017-11-15 |
2020-01-30 |
10X Genomics Inc |
Functionalized gel beads
|
|
US10829815B2
(en)
|
2017-11-17 |
2020-11-10 |
10X Genomics, Inc. |
Methods and systems for associating physical and genetic properties of biological particles
|
|
CN118818037A
(zh)
*
|
2017-12-12 |
2024-10-22 |
10X基因组学有限公司 |
用于单细胞处理的系统和方法
|
|
JP7727385B2
(ja)
|
2017-12-18 |
2025-08-21 |
ヴェンタナ メディカル システムズ, インク. |
ペプチド核酸コンジュゲート
|
|
JP7158642B2
(ja)
*
|
2018-01-16 |
2022-10-24 |
国立大学法人山梨大学 |
質量分析装置及び質量分析システム
|
|
KR101911859B1
(ko)
*
|
2018-02-02 |
2018-12-28 |
주식회사 바이오이즈 |
이중가닥 핵산 신호 프로브 및 이를 이용한 표적분자의 검출방법
|
|
CA3090699A1
(en)
|
2018-02-12 |
2019-08-15 |
Nanostring Technologies, Inc. |
Biomolecular probes and methods of detecting gene and protein expression
|
|
WO2019157529A1
(en)
|
2018-02-12 |
2019-08-15 |
10X Genomics, Inc. |
Methods characterizing multiple analytes from individual cells or cell populations
|
|
CN112262218B
(zh)
|
2018-04-06 |
2024-11-08 |
10X基因组学有限公司 |
用于单细胞处理中的质量控制的系统和方法
|
|
WO2019213294A1
(en)
|
2018-05-03 |
2019-11-07 |
Becton, Dickinson And Company |
High throughput multiomics sample analysis
|
|
US11365409B2
(en)
|
2018-05-03 |
2022-06-21 |
Becton, Dickinson And Company |
Molecular barcoding on opposite transcript ends
|
|
CN110456034B
(zh)
*
|
2018-05-07 |
2022-07-22 |
上海市第十人民医院 |
一种循环肿瘤细胞的检测方法
|
|
WO2019217758A1
(en)
|
2018-05-10 |
2019-11-14 |
10X Genomics, Inc. |
Methods and systems for molecular library generation
|
|
EP3797171B1
(en)
*
|
2018-05-21 |
2025-08-27 |
The Regents of The University of California |
Single cell mapping and transcriptome analysis
|
|
US20200020419A1
(en)
*
|
2018-07-16 |
2020-01-16 |
Flagship Pioneering Innovations Vi, Llc. |
Methods of analyzing cells
|
|
US20200032335A1
(en)
|
2018-07-27 |
2020-01-30 |
10X Genomics, Inc. |
Systems and methods for metabolome analysis
|
|
EP4471156A3
(en)
|
2018-10-01 |
2025-02-26 |
Becton, Dickinson and Company |
Determining 5' transcript sequences
|
|
CN112969789A
(zh)
|
2018-11-08 |
2021-06-15 |
贝克顿迪金森公司 |
使用随机引发的单细胞全转录组分析
|
|
US12529094B2
(en)
|
2018-12-10 |
2026-01-20 |
10X Genomics, Inc. |
Imaging system hardware
|
|
US11459607B1
(en)
|
2018-12-10 |
2022-10-04 |
10X Genomics, Inc. |
Systems and methods for processing-nucleic acid molecules from a single cell using sequential co-partitioning and composite barcodes
|
|
WO2020123319A2
(en)
|
2018-12-10 |
2020-06-18 |
10X Genomics, Inc. |
Methods of using master / copy arrays for spatial detection
|
|
WO2020123384A1
(en)
|
2018-12-13 |
2020-06-18 |
Cellular Research, Inc. |
Selective extension in single cell whole transcriptome analysis
|
|
US11649485B2
(en)
|
2019-01-06 |
2023-05-16 |
10X Genomics, Inc. |
Generating capture probes for spatial analysis
|
|
US11926867B2
(en)
|
2019-01-06 |
2024-03-12 |
10X Genomics, Inc. |
Generating capture probes for spatial analysis
|
|
US11845983B1
(en)
|
2019-01-09 |
2023-12-19 |
10X Genomics, Inc. |
Methods and systems for multiplexing of droplet based assays
|
|
EP4242322B1
(en)
|
2019-01-23 |
2024-08-21 |
Becton, Dickinson and Company |
Oligonucleotides associated with antibodies
|
|
WO2020185312A2
(en)
|
2019-01-25 |
2020-09-17 |
President And Fellows Of Harvard College |
Compositions and method for synthesizing nucleic acids
|
|
US11851683B1
(en)
|
2019-02-12 |
2023-12-26 |
10X Genomics, Inc. |
Methods and systems for selective analysis of cellular samples
|
|
WO2020167920A1
(en)
|
2019-02-14 |
2020-08-20 |
Cellular Research, Inc. |
Hybrid targeted and whole transcriptome amplification
|
|
CN114174531A
(zh)
|
2019-02-28 |
2022-03-11 |
10X基因组学有限公司 |
用空间条码化寡核苷酸阵列对生物分析物进行概况分析
|
|
WO2020190509A1
(en)
|
2019-03-15 |
2020-09-24 |
10X Genomics, Inc. |
Methods for using spatial arrays for single cell sequencing
|
|
WO2020198071A1
(en)
|
2019-03-22 |
2020-10-01 |
10X Genomics, Inc. |
Three-dimensional spatial analysis
|
|
JP7183899B2
(ja)
*
|
2019-03-25 |
2022-12-06 |
株式会社Jvcケンウッド |
分析装置及び分析方法
|
|
CA3134973A1
(en)
*
|
2019-03-27 |
2020-10-01 |
Fluidigm Canada Inc. |
Lyophilized antibody panel
|
|
US11965208B2
(en)
|
2019-04-19 |
2024-04-23 |
Becton, Dickinson And Company |
Methods of associating phenotypical data and single cell sequencing data
|
|
WO2020243579A1
(en)
|
2019-05-30 |
2020-12-03 |
10X Genomics, Inc. |
Methods of detecting spatial heterogeneity of a biological sample
|
|
WO2021016239A1
(en)
|
2019-07-22 |
2021-01-28 |
Becton, Dickinson And Company |
Single cell chromatin immunoprecipitation sequencing assay
|
|
KR102406463B1
(ko)
*
|
2019-09-03 |
2022-06-10 |
재단법인 오송첨단의료산업진흥재단 |
단백질 생산성 향상을 위한 개별 바코딩 시스템 도입한 시그널 펩타이드 초고속 선별방법
|
|
US12235262B1
(en)
|
2019-09-09 |
2025-02-25 |
10X Genomics, Inc. |
Methods and systems for single cell protein analysis
|
|
EP4055185A1
(en)
|
2019-11-08 |
2022-09-14 |
10X Genomics, Inc. |
Spatially-tagged analyte capture agents for analyte multiplexing
|
|
US11773436B2
(en)
|
2019-11-08 |
2023-10-03 |
Becton, Dickinson And Company |
Using random priming to obtain full-length V(D)J information for immune repertoire sequencing
|
|
EP4058598B1
(en)
|
2019-11-13 |
2025-04-23 |
10X Genomics, Inc. |
Generating capture probes for spatial analysis
|
|
JP2023506176A
(ja)
|
2019-12-12 |
2023-02-15 |
プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ |
光誘導型生体分子バーコーディングのための組成物および方法
|
|
CN115244184A
(zh)
|
2020-01-13 |
2022-10-25 |
贝克顿迪金森公司 |
用于定量蛋白和rna的方法和组合物
|
|
CN115335520A
(zh)
|
2020-01-29 |
2022-11-11 |
贝克顿迪金森公司 |
用于通过测序对单细胞进行空间映射的条形码化的孔
|
|
JP7647736B2
(ja)
*
|
2020-02-14 |
2025-03-18 |
ソニーグループ株式会社 |
分析方法、分析システム、及び分析用表面
|
|
US12281357B1
(en)
|
2020-02-14 |
2025-04-22 |
10X Genomics, Inc. |
In situ spatial barcoding
|
|
US12399123B1
(en)
|
2020-02-14 |
2025-08-26 |
10X Genomics, Inc. |
Spatial targeting of analytes
|
|
WO2021173719A1
(en)
|
2020-02-25 |
2021-09-02 |
Becton, Dickinson And Company |
Bi-specific probes to enable the use of single-cell samples as single color compensation control
|
|
US20240018607A1
(en)
*
|
2020-03-31 |
2024-01-18 |
Logicink Corporation |
Molecular beacons
|
|
US20230235379A1
(en)
|
2020-04-30 |
2023-07-27 |
Dimensiongen |
Devices and methods for macromolecular manipulation
|
|
WO2021231779A1
(en)
|
2020-05-14 |
2021-11-18 |
Becton, Dickinson And Company |
Primers for immune repertoire profiling
|
|
US20230212647A1
(en)
*
|
2020-05-29 |
2023-07-06 |
Seer, Inc. |
Systems and methods for rapid identification of proteins
|
|
EP4407030B1
(en)
|
2020-06-02 |
2025-12-17 |
Becton, Dickinson and Company |
Oligonucleotides and beads for 5 prime gene expression assay
|
|
EP4162074B1
(en)
|
2020-06-08 |
2024-04-24 |
10X Genomics, Inc. |
Methods of determining a surgical margin and methods of use thereof
|
|
US11981960B1
(en)
|
2020-07-06 |
2024-05-14 |
10X Genomics, Inc. |
Spatial analysis utilizing degradable hydrogels
|
|
US11932901B2
(en)
|
2020-07-13 |
2024-03-19 |
Becton, Dickinson And Company |
Target enrichment using nucleic acid probes for scRNAseq
|
|
EP4189112A1
(en)
|
2020-07-31 |
2023-06-07 |
Becton Dickinson and Company |
Single cell assay for transposase-accessible chromatin
|
|
US11739443B2
(en)
|
2020-11-20 |
2023-08-29 |
Becton, Dickinson And Company |
Profiling of highly expressed and lowly expressed proteins
|
|
EP4239335A4
(en)
*
|
2020-12-01 |
2024-09-25 |
Kyushu University, National University Corporation |
Biomolecule structure detection probe, biomolecule structure detection kit, and method for detecting biomolecule structure
|
|
EP4263859A1
(en)
|
2020-12-15 |
2023-10-25 |
Becton, Dickinson and Company |
Single cell secretome analysis
|
|
WO2022140028A1
(en)
|
2020-12-21 |
2022-06-30 |
10X Genomics, Inc. |
Methods, compositions, and systems for capturing probes and/or barcodes
|
|
US20240076723A1
(en)
|
2020-12-30 |
2024-03-07 |
10X Genomics, Inc. |
Cleavage of capture probes for spatial analysis
|
|
ES3008686T3
(en)
|
2021-03-18 |
2025-03-24 |
10X Genomics Inc |
Multiplex capture of gene and protein expression from a biological sample
|
|
EP4341847A1
(en)
*
|
2021-05-19 |
2024-03-27 |
Leica Microsystems CMS GmbH |
Marker, method and device for analyzing a biological sample
|
|
JP2024521683A
(ja)
*
|
2021-05-19 |
2024-06-04 |
ライカ マイクロシステムズ シーエムエス ゲゼルシャフト ミット ベシュレンクテル ハフツング |
生体試料を分析するためのマーカー、方法および装置
|
|
WO2022256503A1
(en)
|
2021-06-03 |
2022-12-08 |
10X Genomics, Inc. |
Methods, compositions, kits, and systems for enhancing analyte capture for spatial analysis
|
|
EP4396581A1
(en)
*
|
2021-08-31 |
2024-07-10 |
Becton, Dickinson and Company |
Multiplexed proteomics analysis using oligonucleotide-conjugated antibodies
|
|
WO2023102118A2
(en)
|
2021-12-01 |
2023-06-08 |
10X Genomics, Inc. |
Methods, compositions, and systems for improved in situ detection of analytes and spatial analysis
|
|
US20250144110A1
(en)
*
|
2022-01-28 |
2025-05-08 |
Washington University |
Compositions of autophagy modulating agents and uses thereof
|
|
WO2023250077A1
(en)
|
2022-06-22 |
2023-12-28 |
10X Genomics, Inc. |
Methods, compositions, and systems for capturing probes and/or barcodes
|
|
EP4343326B1
(en)
*
|
2022-09-20 |
2025-03-12 |
Miltenyi Biotec B.V. & Co. KG |
Biological conjugates having an photogenerated acidic or basic releasable detection moiety on top of biological tissues
|
|
WO2024064866A2
(en)
*
|
2022-09-22 |
2024-03-28 |
Astrin Biosciences, Inc. |
Tumor cell profiling-based therapeutic targeting of cancer
|
|
WO2024073524A2
(en)
*
|
2022-09-28 |
2024-04-04 |
Massachusetts Institute Of Technology |
High throughput stochastic bio-molecular sensor
|
|
EP4624590A3
(en)
|
2022-12-30 |
2025-12-24 |
10X Genomics, Inc. |
Methods, compositions, and kits for multiple barcoding and/or high-density spatial barcoding
|
|
KR102869006B1
(ko)
*
|
2023-03-14 |
2025-10-14 |
재단법인 아산사회복지재단 |
다중면역형광염색을 이용한 세포 시료에서 표적 단백질을 검출하는 방법
|
|
WO2025049491A1
(en)
*
|
2023-08-29 |
2025-03-06 |
Genopheno, Llc. |
Novel sampling and genetic comparison and analysis of cannabis components for commercial differentiation
|
|
WO2025188805A1
(en)
*
|
2024-03-04 |
2025-09-12 |
University Of Denver |
Blood based rapid diagnostic system for brain hemorrhage detection and associated methods
|
|
US20250329467A1
(en)
*
|
2024-04-23 |
2025-10-23 |
Delfi Diagnostics, Inc. |
Workflows for discovery and deployment of diagnostic assays combining proteomic and genomic information
|