JP2011524858A5 - - Google Patents

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Publication number
JP2011524858A5
JP2011524858A5 JP2011509761A JP2011509761A JP2011524858A5 JP 2011524858 A5 JP2011524858 A5 JP 2011524858A5 JP 2011509761 A JP2011509761 A JP 2011509761A JP 2011509761 A JP2011509761 A JP 2011509761A JP 2011524858 A5 JP2011524858 A5 JP 2011524858A5
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JP
Japan
Prior art keywords
psgl
binding
human
selectin
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011509761A
Other languages
English (en)
Japanese (ja)
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JP2011524858A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2009/044188 external-priority patent/WO2009140623A2/en
Publication of JP2011524858A publication Critical patent/JP2011524858A/ja
Publication of JP2011524858A5 publication Critical patent/JP2011524858A5/ja
Pending legal-status Critical Current

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JP2011509761A 2008-05-15 2009-05-15 抗ｐｓｇｌ−１抗体並びにその同定及び使用方法 Pending JP2011524858A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12779108P 2008-05-15 2008-05-15
US61/127,791 2008-05-15
PCT/US2009/044188 WO2009140623A2 (en) 2008-05-15 2009-05-15 Anti-psgl-1 antibodies and methods of identification and use

Publications (2)

Publication Number Publication Date
JP2011524858A JP2011524858A (ja) 2011-09-08
JP2011524858A5 true JP2011524858A5 (https=) 2012-05-10

Family

ID=41316376

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011509761A Pending JP2011524858A (ja) 2008-05-15 2009-05-15 抗ｐｓｇｌ−１抗体並びにその同定及び使用方法

Country Status (6)

Country Link
US (2) US7833530B2 (https=)
EP (2) EP2291536A4 (https=)
JP (1) JP2011524858A (https=)
AU (1) AU2009246166B2 (https=)
CA (1) CA2724415C (https=)
WO (1) WO2009140623A2 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE041957T2 (hu) 2006-12-01 2019-06-28 Novartis Ag Anti-P-szelektin antitestek és eljárások azok alkalmazására gyulladásos betegségek kezelésére
US8945565B2 (en) 2006-12-01 2015-02-03 Selexys Pharmaceuticals Corporation Methods of treating inflammatory or thrombotic conditions with anti-P-selectin antibodies
EP2654781B1 (en) * 2010-12-21 2018-01-24 Selexys Pharmaceuticals Corporation Anti-p-selectin antibodies and methods of their use and identification
EP2718325A4 (en) * 2011-06-13 2015-03-11 ABGENOMICS COöPERATIEF U A ANTI-PSGL-1 ANTIBODIES AND USES THEREOF
JP6236255B2 (ja) * 2012-08-31 2017-11-22 旭化成メディカル株式会社 基材及びデバイス
KR20250159733A (ko) 2017-01-11 2025-11-11 브리스톨-마이어스 스큅 컴퍼니 Psgl-1 길항제 및 그의 용도
PE20250933A1 (es) 2017-03-14 2025-04-02 Five Prime Therapeutics Inc Anticuerpos de union a vista a ph acido
AU2018261637A1 (en) * 2017-05-03 2019-12-12 Biomarin Pharmaceutical Inc. Improved lentiviruses for transduction of hematopoietic stem cells.
BR112020019083A2 (pt) 2018-03-21 2020-12-29 Five Prime Therapeutics, Inc. Anticorpos, ácido nucleico, composições, célula e métodos para preparar um anticorpo, para tratar câncer, para tratar uma doença infecciosa, para tratar uma inflamação, para a identificação de um anticorpo, para melhorar a eficácia antitumoral de um anticorpo, para melhorar a farmacocinética de um anticorpo, para selecionar um anticorpo, para melhorar a eficácia de anticorpos, para isolar anticorpos, para detectar vista em uma amostra e para tratar câncer
EP3813881A4 (en) * 2018-06-29 2022-09-14 Verseau Therapeutics, Inc. COMPOSITIONS AND METHODS FOR MODULATION OF MONOCYTE AND MACROPHAGE INFLAMMATION PHENOTYPES AND IMMUNOTHERAPY USES THEREOF
PE20210687A1 (es) 2018-07-11 2021-04-08 Bristol Myers Squibb Co Anticuerpos de union a vista a ph acido
CN112740043A (zh) 2018-07-20 2021-04-30 皮埃尔法布雷医药公司 Vista受体
CA3141334A1 (en) * 2019-06-04 2020-12-10 Verseau Therapeutics, Inc. Anti-psgl-1 compositions and methods for modulating myeloid cell inflammatory phenotypes and uses thereof
KR102242285B1 (ko) * 2019-10-02 2021-04-20 코아스템(주) 중간엽줄기세포의 전신홍반루푸스 치료효과 예측용 바이오마커 조성물
CN113322223B (zh) * 2021-06-03 2023-09-12 重庆市畜牧科学院 富硒酵母基因工程菌及其表面展示系统及其构建方法
CN113667015B (zh) * 2021-08-20 2022-10-11 北京康特泊瑞生物医药科技股份公司 靶向psgl-1蛋白的抗体及其用途
AU2023343549A1 (en) * 2022-09-13 2025-03-20 Tetherex Pharmaceuticals Corporation Antibodies, compositions, and methods of treatment
WO2025191538A1 (en) * 2024-03-14 2025-09-18 Tetherex Pharmaceuticals Corporation Pharmaceutical compositions and methods of treatment

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7016A (en) * 1850-01-15 Mill for grinding
US4179337A (en) 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
US4036945A (en) 1976-05-03 1977-07-19 The Massachusetts General Hospital Composition and method for determining the size and location of myocardial infarcts
JPS6023084B2 (ja) 1979-07-11 1985-06-05 味の素株式会社 代用血液
US4331647A (en) 1980-03-03 1982-05-25 Goldenberg Milton David Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers
JPS5896026A (ja) 1981-10-30 1983-06-07 Nippon Chemiphar Co Ltd 新規ウロキナ−ゼ誘導体およびその製造法ならびにそれを含有する血栓溶解剤
US4640835A (en) 1981-10-30 1987-02-03 Nippon Chemiphar Company, Ltd. Plasminogen activator derivatives
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4496689A (en) 1983-12-27 1985-01-29 Miles Laboratories, Inc. Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
EP0206448B1 (en) 1985-06-19 1990-11-14 Ajinomoto Co., Inc. Hemoglobin combined with a poly(alkylene oxide)
US4766106A (en) 1985-06-26 1988-08-23 Cetus Corporation Solubilization of proteins for pharmaceutical compositions using polymer conjugation
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
US4791192A (en) 1986-06-26 1988-12-13 Takeda Chemical Industries, Ltd. Chemically modified protein with polyethyleneglycol
JP3101690B2 (ja) 1987-03-18 2000-10-23 エス・ビィ・２・インコーポレイテッド 変性抗体の、または変性抗体に関する改良
US5667988A (en) 1992-01-27 1997-09-16 The Scripps Research Institute Methods for producing antibody libraries using universal or randomized immunoglobulin light chains
US6277975B1 (en) * 1992-10-23 2001-08-21 Genetics Institute, Inc. Fusions of P-selectin ligand protein and polynucleotides encoding same
US6551795B1 (en) 1998-02-18 2003-04-22 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to pseudomonas aeruginosa for diagnostics and therapeutics
US7223845B2 (en) 1998-06-16 2007-05-29 The Board Of Regents Of The University Of Oklahoma Synthetic glycosulfopeptides and methods of synthesis thereof
US20090087878A9 (en) 1999-05-06 2009-04-02 La Rosa Thomas J Nucleic acid molecules associated with plants
US7605238B2 (en) * 1999-08-24 2009-10-20 Medarex, Inc. Human CTLA-4 antibodies and their uses
DE60118362T2 (de) * 2000-05-19 2007-05-24 The Center for Blood Research, Inc., Boston VERFAHREN ZUR BEHANDLUNG VON HÄMOSTATISCHEN STÖRUNGEN DURCH LöSLICHES P-SELECTIN
US20040002450A1 (en) * 2000-12-29 2004-01-01 Janette Lazarovits Y17 - isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof
US20040001839A1 (en) * 2000-12-29 2004-01-01 Avigdor Levanon Multimers - isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof
US7744888B2 (en) * 2001-08-03 2010-06-29 Abgenomics Cooperatief U.A. Methods of modulating T cell or natural killer cell activity with anti-P-selectin glycoprotein ligand 1 antibodies
US20040072796A1 (en) * 2002-04-18 2004-04-15 Embury Stephen H. Method and composition for preventing pain in sickle cell patients
JP2007501021A (ja) * 2003-05-30 2007-01-25 アレクシオン ファーマシューティカルズ， インコーポレイテッド 遺伝子操作された定常領域を含む、抗体および融合タンパク質
US20050069955A1 (en) * 2003-06-30 2005-03-31 Daniel Plaksin Antibodies and uses thereof
WO2006124269A2 (en) * 2005-05-16 2006-11-23 Amgen Fremont Inc. Human monoclonal antibodies that bind to very late antigen-1 for the treatment of inflammation and other disorders
US20070160601A1 (en) * 2005-12-09 2007-07-12 Angela Widom Neutralizing antibodies against primate psgl-1 and uses therefor
US20070298034A9 (en) * 2005-12-09 2007-12-27 Angela Widom Sulfotyrosine specific antibodies and uses therefor
US7744879B2 (en) 2006-06-07 2010-06-29 Wisconsin Alumni Research Foundation Blood-brain barrier targeting antibodies

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