JP2011519891A5 - - Google Patents
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- Publication number
- JP2011519891A5 JP2011519891A5 JP2011507892A JP2011507892A JP2011519891A5 JP 2011519891 A5 JP2011519891 A5 JP 2011519891A5 JP 2011507892 A JP2011507892 A JP 2011507892A JP 2011507892 A JP2011507892 A JP 2011507892A JP 2011519891 A5 JP2011519891 A5 JP 2011519891A5
- Authority
- JP
- Japan
- Prior art keywords
- cyclobutyl
- carbonyl
- azetidin
- oxy
- diazepane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 *OC(**#N)=O Chemical compound *OC(**#N)=O 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08155915.5 | 2008-05-08 | ||
| EP08155915 | 2008-05-08 | ||
| US13946108P | 2008-12-19 | 2008-12-19 | |
| US61/139,461 | 2008-12-19 | ||
| PCT/EP2009/055418 WO2009135842A1 (en) | 2008-05-08 | 2009-05-05 | Azetidines and cyclobutanes as histamine h3 receptor antagonists |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011519891A JP2011519891A (ja) | 2011-07-14 |
| JP2011519891A5 true JP2011519891A5 (https=) | 2012-05-10 |
| JP5780954B2 JP5780954B2 (ja) | 2015-09-16 |
Family
ID=39720542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011507892A Expired - Fee Related JP5780954B2 (ja) | 2008-05-08 | 2009-05-05 | ヒスタミンｈ３受容体アンタゴニストとしてのアゼチジン類及びシクロブタン類 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8691804B2 (https=) |
| EP (1) | EP2300422B1 (https=) |
| JP (1) | JP5780954B2 (https=) |
| CN (1) | CN102015636B (https=) |
| BR (1) | BRPI0913057A2 (https=) |
| CA (1) | CA2721303C (https=) |
| IL (1) | IL208613A (https=) |
| TW (1) | TWI454468B (https=) |
| WO (1) | WO2009135842A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SA08290520B1 (ar) | 2007-08-22 | 2012-02-22 | استرازينيكا ايه بي | مشتقات سيكلو بروبيل أميد وتركيبات صيدلية تحتوي عليها لعلاج حالة مرضية سببها مستقبلات هيستامين h3 |
| WO2010086403A1 (en) | 2009-02-02 | 2010-08-05 | Evotec Neurosciences Gmbh | Azetidines as histamine h3 receptor antagonists |
| TW201039825A (en) | 2009-02-20 | 2010-11-16 | Astrazeneca Ab | Cyclopropyl amide derivatives 983 |
| US20120189546A1 (en) * | 2009-07-11 | 2012-07-26 | Bayer Pharma Aktiengesellschaft | Radiolabelling Method Using Cycloalkyl Groups |
| RU2012139082A (ru) * | 2010-02-18 | 2014-03-27 | Астразенека Аб | Способы получения производных циклопропиламида и связанных с ними промежуточных соединений |
| SA111320581B1 (ar) * | 2010-07-06 | 2014-06-17 | استرازينيكا ايه بي | مركبات (3-(4-(أمينو ميثيل ) فينوكسي أو فينيل ثيو) أزيتيدين -1- يل) (5- فينيل -1، 3، 4- أوكسا ديازول -2- يل) ميثانون |
| EP2694492B1 (en) | 2011-02-23 | 2015-07-29 | Suven Life Sciences Limited | Novel compounds as histamine h3 receptor ligands |
| UY34194A (es) | 2011-07-15 | 2013-02-28 | Astrazeneca Ab | ?(3-(4-(espiroheterocíclico)metil)fenoxi)azetidin-1-il)(5-(fenil)-1,3,4-oxadiazol-2-il)metanona en el tratamiento de la obesidad? |
| WO2013151982A1 (en) | 2012-04-03 | 2013-10-10 | Arena Pharmaceuticals, Inc. | Methods and compounds useful in treating pruritus, and methods for identifying such compounds |
| CA2878217C (en) | 2012-08-23 | 2016-05-17 | Suven Life Sciences Limited | Acrylamide compounds as histamine h3 receptor ligands |
| CN104603104B (zh) * | 2012-09-05 | 2016-12-07 | 浙江海正药业股份有限公司 | 氮杂环丁烷酮化合物的晶型及其制备方法 |
| US20230130739A1 (en) | 2020-03-26 | 2023-04-27 | Cyclerion Therapeutics, Inc. | DEUTERATED sGC STIMULATORS |
| CN112279809A (zh) * | 2020-09-23 | 2021-01-29 | 山东省海洋化工科学研究院 | 一种2-氰基-4-氟吡啶的制备方法 |
| CN115073276A (zh) * | 2022-07-15 | 2022-09-20 | 济南大学 | 一种泊沙康唑主环杂质的制备及控制方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA861210B (en) * | 1985-02-28 | 1987-10-28 | Robins Co Inc A H | 3-aryloxyazetidinecarboxamides as anticonvulsants and antiepileptics |
| US4956359A (en) | 1985-02-28 | 1990-09-11 | A. H. Robins Company, Inc. | 3-aryloxy and 3-arylthioazetidinecarboxamides as anticonvulsants and antiepileptics |
| US6559140B2 (en) | 2000-03-09 | 2003-05-06 | Abbott Laboratories | Cyclic and bicyclic diamino histamine-3 receptor antagonists |
| EP1421071B1 (en) * | 2001-07-02 | 2009-11-18 | High Point Pharmaceuticals, LLC | Substituted piperazine and diazepane derivaives as histamine h3 receptor modulators |
| DE10150310A1 (de) * | 2001-10-11 | 2003-04-24 | Bayer Ag | Substituierte Piperazincyclohexancarbonsäureamide und ihre Verwendung |
| EP1802307B1 (en) | 2004-10-15 | 2008-02-27 | Glaxo Group Limited | Pyrrolidine derivatives as histamine receptors ligands |
| JP2008543923A (ja) | 2005-06-22 | 2008-12-04 | ファイザー・プロダクツ・インク | ヒスタミン−３受容体アンタゴニスト |
| US8158673B2 (en) * | 2005-10-27 | 2012-04-17 | Pfizer Inc. | Histamine-3 receptor antagonists |
| US20070142369A1 (en) | 2005-12-21 | 2007-06-21 | Margaret Van Heek | Combination of an H3 antagonist/inverse agonist and an appetite suppressant |
| AU2007204426A1 (en) | 2006-01-13 | 2007-07-19 | F. Hoffmann-La Roche Ag | Cyclohexyl piperazinyl methanone derivatives and their use as histamine H3 receptor modulators |
| US8106208B2 (en) | 2006-05-18 | 2012-01-31 | Albireo Ab | Benzamide compounds that act as NK receptor antagonists |
| EA018582B1 (ru) | 2007-11-20 | 2013-09-30 | Янссен Фармацевтика Н.В. | Соединения циклоалкилокси- и гетероциклоалкилоксипиридина как модуляторы гистаминового рецептора н |
-
2009
- 2009-05-05 BR BRPI0913057A patent/BRPI0913057A2/pt not_active Application Discontinuation
- 2009-05-05 EP EP09742060.8A patent/EP2300422B1/en active Active
- 2009-05-05 JP JP2011507892A patent/JP5780954B2/ja not_active Expired - Fee Related
- 2009-05-05 US US12/991,225 patent/US8691804B2/en active Active
- 2009-05-05 CA CA2721303A patent/CA2721303C/en active Active
- 2009-05-05 WO PCT/EP2009/055418 patent/WO2009135842A1/en not_active Ceased
- 2009-05-05 CN CN200980117615.XA patent/CN102015636B/zh not_active Expired - Fee Related
- 2009-05-07 TW TW098115068A patent/TWI454468B/zh not_active IP Right Cessation
-
2010
- 2010-10-11 IL IL208613A patent/IL208613A/en active IP Right Grant
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