JP2006528147A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2006528147A5 JP2006528147A5 JP2006520762A JP2006520762A JP2006528147A5 JP 2006528147 A5 JP2006528147 A5 JP 2006528147A5 JP 2006520762 A JP2006520762 A JP 2006520762A JP 2006520762 A JP2006520762 A JP 2006520762A JP 2006528147 A5 JP2006528147 A5 JP 2006528147A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- formula
- group
- compound
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0316893A GB0316893D0 (en) | 2003-07-18 | 2003-07-18 | Novel compounds |
| GB0411167A GB0411167D0 (en) | 2004-05-19 | 2004-05-19 | Novel compounds |
| PCT/EP2004/008061 WO2005014571A1 (en) | 2003-07-18 | 2004-07-16 | Substituted piperidines as histamine h3 receptor ligands |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006528147A JP2006528147A (ja) | 2006-12-14 |
| JP2006528147A5 true JP2006528147A5 (https=) | 2007-07-19 |
Family
ID=34137741
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006520762A Pending JP2006528147A (ja) | 2003-07-18 | 2004-07-16 | ヒスタミンｈ３受容体リガンドとしての置換ピペリジン |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20060247227A1 (https=) |
| EP (1) | EP1646620B1 (https=) |
| JP (1) | JP2006528147A (https=) |
| AR (1) | AR045999A1 (https=) |
| AT (1) | ATE370135T1 (https=) |
| DE (1) | DE602004008291T2 (https=) |
| ES (1) | ES2291913T3 (https=) |
| TW (1) | TW200514781A (https=) |
| WO (1) | WO2005014571A1 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007010350A1 (en) * | 2005-07-19 | 2007-01-25 | Pfizer Products Inc. | Synthesis of therapeutic diphenyl ethers |
| US7851474B2 (en) | 2005-08-02 | 2010-12-14 | Neurogen Corporation | Dipiperazinyl ketones and related analogues |
| CA2687931C (en) | 2007-05-31 | 2016-05-24 | Boehringer Ingelheim International Gmbh | Ccr2 receptor antagonists and uses thereof |
| CN101878209A (zh) * | 2007-09-28 | 2010-11-03 | 先灵公司 | 作为组胺受体拮抗剂的氧哌啶衍生物 |
| HUE025547T2 (en) | 2008-12-19 | 2016-02-29 | Boehringer Ingelheim Int | Cyclic pyrimidine-4-carboxamides as CCR2 receptor antagonists for the treatment of inflammation, asthma and COPD |
| ES2674275T3 (es) | 2009-12-17 | 2018-06-28 | Centrexion Therapeutics Corporation | Antagonistas del receptor CCR2 y usos de los mismos |
| EP2569298B1 (en) | 2010-05-12 | 2015-11-25 | Boehringer Ingelheim International GmbH | Novel ccr2 receptor antagonists, method for producing the same, and use thereof as medicaments |
| WO2011141477A1 (en) | 2010-05-12 | 2011-11-17 | Boehringer Ingelheim International Gmbh | New ccr2 receptor antagonists, method for producing the same, and use thereof as medicaments |
| WO2011144501A1 (en) | 2010-05-17 | 2011-11-24 | Boehringer Ingelheim International Gmbh | Ccr2 antagonists and uses thereof |
| CN102260277B (zh) | 2010-05-24 | 2013-07-24 | 中国科学院上海药物研究所 | 新型苯并噁嗪噁唑烷酮类化合物及其制备方法和用途 |
| EP2576542B1 (en) | 2010-05-25 | 2015-04-22 | Boehringer Ingelheim International GmbH | Cyclic amide derivatives of pyridazine-3-carboxylic acids and their use in the treatment of pulmonary, pain, immune related and cardiovascular diseases |
| EP2576538B1 (en) | 2010-06-01 | 2015-10-28 | Boehringer Ingelheim International GmbH | New CCR2 antagonists |
| BR112013002112B1 (pt) | 2010-07-29 | 2021-04-06 | Rigel Pharmaceuticals, Inc. | Composto, composição farmacêutica, e, uso de um composto, ou de um respectivo sal farmaceuticamente aceitável, ou de uma composição |
| EP2731941B1 (en) | 2011-07-15 | 2019-05-08 | Boehringer Ingelheim International GmbH | Novel and selective ccr2 antagonists |
| EP2804853A4 (en) * | 2012-01-16 | 2015-09-23 | Glaxosmithkline Ip Dev Ltd | THERAPEUTIC USES |
| CN104114538B (zh) * | 2012-01-16 | 2016-04-13 | 葛兰素史克知识产权发展有限公司 | 治疗用途 |
| WO2013151982A1 (en) | 2012-04-03 | 2013-10-10 | Arena Pharmaceuticals, Inc. | Methods and compounds useful in treating pruritus, and methods for identifying such compounds |
| EP2647377A1 (en) | 2012-04-06 | 2013-10-09 | Sanofi | Use of an h3 receptor antagonist for the treatment of alzheimer's disease |
| MX383744B (es) | 2015-07-02 | 2025-03-14 | Centrexion Therapeutics Corp | Citrato de (4-((3r,4r)-3-metoxitetrahidro-piran-4-ilamino)piperidin-1-il) (5-metil-6-(((2r, 6s)-6-(p-tolil)tetrahidro-2h-piran-2-il) metilamino) pirimidin-4-il) metanona. |
| EP3383853B1 (en) | 2015-12-01 | 2020-11-04 | Merck Sharp & Dohme Corp. | Homobispiperidinyl derivatives as liver x receptor (lxr) beta agonists for treating e.g. alzheimer's disease |
| AU2023247609A1 (en) * | 2022-03-31 | 2024-10-17 | Bebetter Med Inc. | 1,4-diheterocyclic substituted aromatic ring or aromatic heterocyclic compound and use thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20020507A1 (es) * | 2000-10-17 | 2002-06-25 | Schering Corp | Compuestos no-imidazoles como antagonistas del receptor histamina h3 |
| AU2002253929A1 (en) * | 2001-02-08 | 2002-09-24 | Schering Corporation | Use of dual h3/m2 antagonists with a bipiperidinic structure in the treatment of cognition deficit disorders |
| EP2243776A1 (en) * | 2001-10-12 | 2010-10-27 | High Point Pharmaceuticals, LLC | Substituted piperidines and their use for the treatment of diseases related to the histamine H3 receptor |
| AU2003242252A1 (en) * | 2002-06-07 | 2003-12-22 | Kyowa Hakko Kogyo Co., Ltd. | Bicyclic pyrimidine derivatives |
-
2004
- 2004-07-16 WO PCT/EP2004/008061 patent/WO2005014571A1/en not_active Ceased
- 2004-07-16 JP JP2006520762A patent/JP2006528147A/ja active Pending
- 2004-07-16 EP EP04763339A patent/EP1646620B1/en not_active Expired - Lifetime
- 2004-07-16 DE DE602004008291T patent/DE602004008291T2/de not_active Expired - Fee Related
- 2004-07-16 US US10/564,931 patent/US20060247227A1/en not_active Abandoned
- 2004-07-16 AR ARP040102526A patent/AR045999A1/es unknown
- 2004-07-16 AT AT04763339T patent/ATE370135T1/de not_active IP Right Cessation
- 2004-07-16 TW TW093121228A patent/TW200514781A/zh unknown
- 2004-07-16 ES ES04763339T patent/ES2291913T3/es not_active Expired - Lifetime
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2006528147A5 (https=) | ||
| JP6978507B2 (ja) | Ｃｆｔｒ増強物質としてのピロロピリミジン | |
| JP6704398B2 (ja) | ４Ｈ−ピロロ［３，２−ｃ］ピリジン−４−オン誘導体 | |
| CN104125957B (zh) | 取代的苄基吡唑 | |
| JP6387360B2 (ja) | 変異ｉｄｈの阻害薬としての３−ピリミジン−４−イル−オキサゾリジン−２−オン | |
| KR101985050B1 (ko) | 피라진카르복사미드 화합물 | |
| WO2012000304A1 (zh) | 杂环炔苯类化合物及其药用组合物和应用 | |
| JP2009541311A5 (https=) | ||
| JP2017525757A5 (https=) | ||
| JP2013539777A5 (https=) | ||
| JP2011515462A5 (https=) | ||
| JP2014526549A5 (https=) | ||
| UA111754C2 (uk) | Заміщені бензиліндазоли для застосування як інгібіторів bub1-кінази для лікування гіперпроліферативних захворювань | |
| JP2008513514A5 (https=) | ||
| WO2011093501A1 (ja) | Ｇｐｒ１１９作動薬 | |
| TW202106683A (zh) | 4H-吡咯并[3,2-c]吡啶-4-酮化合物 | |
| JP2006508935A5 (https=) | ||
| JP2006506380A5 (https=) | ||
| WO2012117996A1 (ja) | Ｇｐｒ１１９作動薬 | |
| WO2015152367A1 (ja) | オキソ複素環誘導体 | |
| JP2021523177A5 (https=) | ||
| JP2019511466A (ja) | オレキシン受容体調節因子としてのハロ置換ピペリジン | |
| US20090149469A1 (en) | Phenyl-[4-(3-phenyl-1h-pyrazol-4-yl)-pyrimidin-2-yl]-amine derivatives as igf-ir inhibitors | |
| JP2009501745A5 (https=) | ||
| JP2009537606A5 (https=) |