JP2021523177A5 - - Google Patents
Info
- Publication number
- JP2021523177A5 JP2021523177A5 JP2020563691A JP2020563691A JP2021523177A5 JP 2021523177 A5 JP2021523177 A5 JP 2021523177A5 JP 2020563691 A JP2020563691 A JP 2020563691A JP 2020563691 A JP2020563691 A JP 2020563691A JP 2021523177 A5 JP2021523177 A5 JP 2021523177A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- pyrimidine
- triazolo
- trimethyl
- pyrrolidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862670075P | 2018-05-11 | 2018-05-11 | |
| US62/670,075 | 2018-05-11 | ||
| PCT/EP2019/062020 WO2019215316A1 (en) | 2018-05-11 | 2019-05-10 | Triazolopyrimidine compounds and their use in treating cancer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021523177A JP2021523177A (ja) | 2021-09-02 |
| JP2021523177A5 true JP2021523177A5 (https=) | 2022-05-16 |
| JP7418353B2 JP7418353B2 (ja) | 2024-01-19 |
Family
ID=66484070
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020563691A Active JP7418353B2 (ja) | 2018-05-11 | 2019-05-10 | トリアゾロピリミジン化合物およびがんの処置におけるそれらの使用 |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US11084827B2 (https=) |
| EP (2) | EP3790879B1 (https=) |
| JP (1) | JP7418353B2 (https=) |
| KR (1) | KR102863374B1 (https=) |
| CN (3) | CN115028636A (https=) |
| AR (1) | AR115384A1 (https=) |
| AU (1) | AU2019264826B2 (https=) |
| BR (1) | BR112020023068A2 (https=) |
| CA (1) | CA3099579A1 (https=) |
| DK (1) | DK3790879T3 (https=) |
| ES (1) | ES2927244T3 (https=) |
| MX (1) | MX2020012058A (https=) |
| PT (1) | PT3790879T (https=) |
| TW (1) | TWI823932B (https=) |
| UY (1) | UY38228A (https=) |
| WO (1) | WO2019215316A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI823932B (zh) * | 2018-05-11 | 2023-12-01 | 中國大陸商迪哲（江蘇）醫藥有限公司 | 三唑并嘧啶化合物及其在治療癌症中之用途 |
| MX2022010634A (es) * | 2020-02-28 | 2023-01-19 | Remix Therapeutics Inc | Derivados de piridazina para modular el empalme de acidos nucleicos. |
| WO2021236893A1 (en) * | 2020-05-21 | 2021-11-25 | Teon Therapeutics, Inc. | Monocarboxylic acid transporter 4 (mct4) modulators and uses thereof |
| WO2021249969A1 (en) * | 2020-06-10 | 2021-12-16 | Merck Patent Gmbh | Combination product for the treatment of cancer diseases |
| AU2021372815A1 (en) | 2020-11-02 | 2023-06-22 | Ares Trading S.A. | Combination treatment of cancer |
| WO2022243574A1 (en) | 2021-05-21 | 2022-11-24 | Cemm - Forschungszentrum Für Molekulare Medizin Gmbh | 3-(phthalazin-1-yl)benzenesulfonamide-based slc16a3 inhibitors and their therapeutic use |
| WO2022243573A1 (en) | 2021-05-21 | 2022-11-24 | Cemm - Forschungszentrum Für Molekulare Medizin Gmbh | 1,2,4-triazolo[1,5-a]pyrimidine-based slc16a3 inhibitors and their therapeutic use |
| CN120699024A (zh) * | 2024-03-25 | 2025-09-26 | 北京福元医药股份有限公司 | Mct4抑制剂及其药物组合物和用途 |
| CN121735952A (zh) * | 2026-02-26 | 2026-03-27 | 山东齐都药业有限公司 | 维立西呱的制备方法及其中间产物 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040072746A1 (en) * | 2001-10-16 | 2004-04-15 | Michael Sullivan | Inhibitors of monocarboxylate transport |
| SE0300119D0 (sv) | 2003-01-17 | 2003-01-17 | Astrazeneca Ab | Novel compounds |
| DE102005034905A1 (de) | 2005-07-26 | 2007-02-01 | Federal-Mogul Nürnberg GmbH | Verfahren zur Herstellung eines Kolbens für einen Verbrennungsmotor sowie Kolben für einen Verbrennungsmotor |
| WO2010089580A1 (en) | 2009-02-06 | 2010-08-12 | Astrazeneca Ab | Use of a mct1 inhibitor in the treatment of cancers expressing mct1 over mct4 |
| WO2011114148A1 (en) | 2010-03-17 | 2011-09-22 | Astrazeneca Ab | 4h- [1, 2, 4] triazolo [5, 1 -b] pyrimidin-7 -one derivatives as ccr2b receptor antagonists |
| WO2016118823A1 (en) * | 2015-01-22 | 2016-07-28 | The Scripps Research Institute | Pteridine dione monocarboxylate transporter inhibitors |
| CA2974697A1 (en) * | 2015-01-22 | 2016-07-28 | The Scripps Research Institute | Pyrimidine-2,4-(1h,3h)-dione derivatives and pharmaceutical compositions thereof and their use as inhibitors of monocarboxylate transporters |
| EP3942934A1 (en) * | 2015-06-12 | 2022-01-26 | Vettore, LLC | Mct4 inhibitors for treating disease |
| US20190135747A1 (en) * | 2016-05-12 | 2019-05-09 | Regents Of The University Of Minnesota | Indole and indazole cyanocinnamate compounds and therapeutic uses thereof |
| TWI823932B (zh) * | 2018-05-11 | 2023-12-01 | 中國大陸商迪哲（江蘇）醫藥有限公司 | 三唑并嘧啶化合物及其在治療癌症中之用途 |
-
2019
- 2019-05-07 TW TW108115719A patent/TWI823932B/zh active
- 2019-05-10 AU AU2019264826A patent/AU2019264826B2/en active Active
- 2019-05-10 EP EP19723404.0A patent/EP3790879B1/en active Active
- 2019-05-10 CA CA3099579A patent/CA3099579A1/en active Pending
- 2019-05-10 MX MX2020012058A patent/MX2020012058A/es unknown
- 2019-05-10 PT PT197234040T patent/PT3790879T/pt unknown
- 2019-05-10 WO PCT/EP2019/062020 patent/WO2019215316A1/en not_active Ceased
- 2019-05-10 KR KR1020207035470A patent/KR102863374B1/ko active Active
- 2019-05-10 CN CN202210528891.2A patent/CN115028636A/zh active Pending
- 2019-05-10 UY UY38228A patent/UY38228A/es not_active Application Discontinuation
- 2019-05-10 JP JP2020563691A patent/JP7418353B2/ja active Active
- 2019-05-10 CN CN202210528893.1A patent/CN115028637B/zh active Active
- 2019-05-10 DK DK19723404.0T patent/DK3790879T3/da active
- 2019-05-10 AR ARP190101254A patent/AR115384A1/es unknown
- 2019-05-10 ES ES19723404T patent/ES2927244T3/es active Active
- 2019-05-10 CN CN201980046079.2A patent/CN112469721B/zh active Active
- 2019-05-10 BR BR112020023068-5A patent/BR112020023068A2/pt active IP Right Grant
- 2019-05-10 EP EP22181542.6A patent/EP4134368A1/en active Pending
-
2020
- 2020-11-11 US US17/095,729 patent/US11084827B2/en active Active
-
2021
- 2021-07-05 US US17/367,450 patent/US11851432B2/en active Active
-
2023
- 2023-11-14 US US18/508,257 patent/US12503473B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021523177A5 (https=) | ||
| JP2022531801A5 (https=) | ||
| US10766902B2 (en) | Wee-1 inhibiting pyrazolopyrimidinone compounds | |
| US20230146795A1 (en) | Enhancement of anti-tumor activity of shp2 inhibitor pyrimidinone in combination with novel cancer medicines in cancers | |
| EP3183247B1 (en) | Aminopyrimidinyl compounds as jak inhibitors | |
| US20250122222A1 (en) | Heterocyclic compounds and methods of use | |
| RU2473549C2 (ru) | Пиримидиновые соединения, композиции и способы применения | |
| US20230192709A1 (en) | Fgfr inhibitors and methods of use thereof | |
| JP6435323B2 (ja) | 炎症性障害の治療のための新規化合物及びその医薬組成物 | |
| WO2024076670A2 (en) | Tethered heterocyclic inhibitors of kras g12c mutant proteins and uses thereof | |
| US8791125B2 (en) | Dihydropyrazolopyrimidinone derivatives | |
| ES2727376T3 (es) | Derivados de aminotriazina útiles como compuestos inhibidores de quinasa de unión TANK | |
| JP2012501312A5 (https=) | ||
| US20230406860A1 (en) | Heterocyclic spiro compounds and methods of use | |
| JP2022552324A5 (https=) | ||
| JP2012525395A5 (https=) | ||
| JP2013523884A5 (https=) | ||
| JP2020505454A (ja) | 化合物 | |
| JP2010510319A5 (https=) | ||
| JP2019514878A5 (https=) | ||
| JP2019535689A5 (https=) | ||
| JP2011511034A5 (https=) | ||
| CN105732637B (zh) | 杂芳化合物及其在药物中的应用 | |
| RU2012113593A (ru) | Ингибиторы jak | |
| US11529350B2 (en) | Tyrosine kinase non-receptor 1 (TNK1) inhibitors and uses thereof |