JP2011516063A5 - - Google Patents
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- Publication number
- JP2011516063A5 JP2011516063A5 JP2011502991A JP2011502991A JP2011516063A5 JP 2011516063 A5 JP2011516063 A5 JP 2011516063A5 JP 2011502991 A JP2011502991 A JP 2011502991A JP 2011502991 A JP2011502991 A JP 2011502991A JP 2011516063 A5 JP2011516063 A5 JP 2011516063A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- myo
- inositol
- gene
- optionally
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 210000004027 cell Anatomy 0.000 claims 30
- 108090000623 proteins and genes Proteins 0.000 claims 15
- 239000002253 acid Substances 0.000 claims 13
- 108020004707 nucleic acids Proteins 0.000 claims 8
- 102000039446 nucleic acids Human genes 0.000 claims 8
- 150000007523 nucleic acids Chemical class 0.000 claims 8
- 102000010081 Inositol Oxygenase Human genes 0.000 claims 7
- 108010077393 Inositol oxygenase Proteins 0.000 claims 7
- 101710088194 Dehydrogenase Proteins 0.000 claims 6
- 102000018463 Myo-Inositol-1-Phosphate Synthase Human genes 0.000 claims 6
- 108091000020 Myo-Inositol-1-Phosphate Synthase Proteins 0.000 claims 6
- 238000004519 manufacturing process Methods 0.000 claims 3
- 238000010188 recombinant method Methods 0.000 claims 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
- 241000238631 Hexapoda Species 0.000 claims 2
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 2
- 230000001580 bacterial effect Effects 0.000 claims 2
- 238000012258 culturing Methods 0.000 claims 2
- 239000013604 expression vector Substances 0.000 claims 2
- 230000002538 fungal effect Effects 0.000 claims 2
- 230000003834 intracellular effect Effects 0.000 claims 2
- 238000003259 recombinant expression Methods 0.000 claims 2
- 210000005253 yeast cell Anatomy 0.000 claims 2
- 241000589155 Agrobacterium tumefaciens Species 0.000 claims 1
- 241000894006 Bacteria Species 0.000 claims 1
- 108010077805 Bacterial Proteins Proteins 0.000 claims 1
- 108020004705 Codon Proteins 0.000 claims 1
- 241000588724 Escherichia coli Species 0.000 claims 1
- 241000589776 Pseudomonas putida Species 0.000 claims 1
- 241000589615 Pseudomonas syringae Species 0.000 claims 1
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims 1
- 108700029229 Transcriptional Regulatory Elements Proteins 0.000 claims 1
- 108010015746 Uronate dehydrogenase Proteins 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 210000004102 animal cell Anatomy 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 210000003527 eukaryotic cell Anatomy 0.000 claims 1
- 210000004962 mammalian cell Anatomy 0.000 claims 1
- 230000037353 metabolic pathway Effects 0.000 claims 1
- 244000005700 microbiome Species 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 238000005457 optimization Methods 0.000 claims 1
- 239000013612 plasmid Substances 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 210000001236 prokaryotic cell Anatomy 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108700026220 vif Genes Proteins 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4250208P | 2008-04-04 | 2008-04-04 | |
| US61/042,502 | 2008-04-04 | ||
| PCT/US2009/002111 WO2009145838A2 (en) | 2008-04-04 | 2009-04-03 | Cellular production of glucaric acid |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016190435A Division JP2017018140A (ja) | 2008-04-04 | 2016-09-28 | グルカン酸の細胞での産生 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011516063A JP2011516063A (ja) | 2011-05-26 |
| JP2011516063A5 true JP2011516063A5 (enExample) | 2013-06-13 |
| JP6196016B2 JP6196016B2 (ja) | 2017-09-13 |
Family
ID=41377836
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011502991A Active JP6196016B2 (ja) | 2008-04-04 | 2009-04-03 | グルカン酸の細胞での産生 |
| JP2016190435A Pending JP2017018140A (ja) | 2008-04-04 | 2016-09-28 | グルカン酸の細胞での産生 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016190435A Pending JP2017018140A (ja) | 2008-04-04 | 2016-09-28 | グルカン酸の細胞での産生 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US8835147B2 (enExample) |
| EP (1) | EP2274417B1 (enExample) |
| JP (2) | JP6196016B2 (enExample) |
| KR (1) | KR101625443B1 (enExample) |
| CN (1) | CN102066552B (enExample) |
| CA (1) | CA2720526C (enExample) |
| DK (1) | DK2274417T3 (enExample) |
| WO (1) | WO2009145838A2 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI20086236A0 (fi) * | 2008-12-23 | 2008-12-23 | Valtion Teknillinen | Heksuronihapon konversio heksarihapoksi |
| KR101740848B1 (ko) | 2011-11-14 | 2017-05-26 | 아사히 가세이 케미칼즈 가부시키가이샤 | 미오이노시톨 및 미오이노시톨 유도체의 제조 방법 |
| EP2818552B1 (en) * | 2012-02-24 | 2017-12-27 | Asahi Kasei Kabushiki Kaisha | Method for producing glucaric acid |
| US9803209B2 (en) | 2012-05-18 | 2017-10-31 | Novozymes A/S | Bacterial mutants with improved transformation efficiency |
| CN105026548B (zh) * | 2012-06-04 | 2019-06-18 | 盐水港精糖株式会社 | D-葡萄糖二酸生产菌及d-葡萄糖二酸的制造方法 |
| BR112015006255A2 (pt) * | 2012-09-21 | 2017-08-22 | Synthetic Genomics Inc | Métodos para a produção de produtos químicos e derivados dos mesmos |
| US9528133B2 (en) | 2012-09-21 | 2016-12-27 | Synthetic Genomics, Inc. | Compositions and methods for producing chemicals and derivatives thereof |
| CN106414753A (zh) * | 2014-03-21 | 2017-02-15 | 合成基因组股份有限公司 | 用于生产化学品及其衍生物的组合物和方法 |
| US20170130210A1 (en) * | 2014-06-09 | 2017-05-11 | Massachusetts Institute Of Technology | Dynamic knockdown of central metabolism for redirecting glucose-6-phosphate fluxes |
| CN104312934A (zh) * | 2014-10-22 | 2015-01-28 | 江南大学 | 一种构建重组酵母生物合成葡萄糖醛酸的方法 |
| CN104312935B (zh) * | 2014-10-22 | 2018-07-06 | 江南大学 | 一种构建重组酵母发酵生产葡萄糖二酸的方法 |
| EP3480305A4 (en) | 2016-06-30 | 2020-01-22 | Cj Cheiljedang Corporation | METHOD FOR THE ENZYMATIC PRODUCTION OF HIGHLY CONCENTRATED MYO-INOSITOL |
| CN106148292B (zh) * | 2016-07-06 | 2019-05-17 | 江南大学 | 一种肌醇加氧酶突变体及其应用 |
| EP3519567A4 (en) * | 2016-10-03 | 2020-06-03 | The Regents of The University of California | MANIPULATED MICROORGANISMS FOR THE PRODUCTION OF CHEMICAL BASIC MATERIALS AND CELL BIOMASS |
| FR3067350B1 (fr) | 2017-06-12 | 2020-12-11 | Seprosys | Procede d'obtention d'une solution d'acide glucarique libre et solution obtenue |
| HUE061086T2 (hu) | 2017-06-22 | 2023-05-28 | Archer Daniels Midland Co | Eljárás furándikarbonsav-észterek elõállítására |
| CN107365806B (zh) * | 2017-08-02 | 2020-04-03 | 南京师范大学 | 一种葡萄糖二酸的制备方法及其制备中的糖醛酸脱氢酶-nadh氧化酶和应用 |
| CA3138481A1 (en) * | 2019-05-17 | 2020-11-26 | The Governing Council Of The University Of Toronto | Enzymatic production of glucaric acid from glucuronic acid |
| CN110846436B (zh) * | 2019-12-25 | 2021-09-28 | 江南大学 | 一种快速鉴别Ale和Lager型啤酒酵母的方法 |
| CN111019852B (zh) * | 2019-12-31 | 2021-11-23 | 江南大学 | 一种提高酿酒酵母工程菌株合成葡萄糖二酸效率的方法 |
| CN110951794B (zh) * | 2019-12-31 | 2022-03-25 | 江南大学 | 一种提高酿酒酵母工程菌生产葡萄糖二酸的发酵方法 |
| KR102649855B1 (ko) * | 2020-09-15 | 2024-03-22 | 경북대학교 산학협력단 | 갈락투론산을 발효하여 뮤식산을 생산하는 신규 효모 균주 |
| WO2022204246A1 (en) * | 2021-03-26 | 2022-09-29 | Archer-Daniels-Midland Company | Thermostable d-glucarate dehydratase that is resistant to inhibition by tartrate sequence submission |
| KR102626750B1 (ko) * | 2021-12-27 | 2024-01-19 | 한국프라임제약주식회사 | 키로이노시톨 생성능이 우수한 락티카제이 바실러스 카제이 WiKim0135 균주 및 이의 혈당강하 용도 |
| CN115820761A (zh) * | 2022-11-28 | 2023-03-21 | 南京工业大学 | 一种生物法催化合成d-葡萄糖醛酸的方法 |
| WO2024217529A1 (zh) * | 2023-04-21 | 2024-10-24 | 西湖大学 | 一种新型的葡萄糖二酸生物合成路径及发酵生产葡萄糖二酸的方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| DE19604798A1 (de) * | 1996-02-09 | 1997-08-14 | Herbstreith & Fox Kg Pektin Fa | Herstellung von L-Ascorbinsäure |
| JP2004536577A (ja) | 2001-03-19 | 2004-12-09 | カーギル，インコーポレーテッド | ミオイノシトールオキシゲナーゼ |
-
2009
- 2009-04-03 WO PCT/US2009/002111 patent/WO2009145838A2/en not_active Ceased
- 2009-04-03 JP JP2011502991A patent/JP6196016B2/ja active Active
- 2009-04-03 KR KR1020107024705A patent/KR101625443B1/ko active Active
- 2009-04-03 CN CN200980120747.8A patent/CN102066552B/zh active Active
- 2009-04-03 DK DK09755201.2T patent/DK2274417T3/da active
- 2009-04-03 CA CA2720526A patent/CA2720526C/en active Active
- 2009-04-03 EP EP09755201.2A patent/EP2274417B1/en active Active
- 2009-04-03 US US12/935,983 patent/US8835147B2/en active Active
-
2014
- 2014-08-05 US US14/452,066 patent/US20150093794A1/en not_active Abandoned
-
2016
- 2016-09-28 JP JP2016190435A patent/JP2017018140A/ja active Pending
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