DK2274417T3 - Cellulær produktion af glucarsyre - Google Patents

Cellulær produktion af glucarsyre

Info

Publication number
DK2274417T3
DK2274417T3 DK09755201.2T DK09755201T DK2274417T3 DK 2274417 T3 DK2274417 T3 DK 2274417T3 DK 09755201 T DK09755201 T DK 09755201T DK 2274417 T3 DK2274417 T3 DK 2274417T3
Authority
DK
Denmark
Prior art keywords
cellular production
glucuric acid
glucuric
acid
cellular
Prior art date
Application number
DK09755201.2T
Other languages
English (en)
Inventor
Sang-Hwal Yoon
Tae Seok Moon
Kristala Lanett Jones Prather
Original Assignee
Massachusetts Inst Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Inst Technology filed Critical Massachusetts Inst Technology
Application granted granted Critical
Publication of DK2274417T3 publication Critical patent/DK2274417T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/58—Aldonic, ketoaldonic or saccharic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8245—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified carbohydrate or sugar alcohol metabolism, e.g. starch biosynthesis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0069—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/02—Monosaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01203—Uronate dehydrogenase (1.1.1.203)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y113/00—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13)
    • C12Y113/99—Miscellaneous (1.13.99)
    • C12Y113/99001—Inositol oxygenase (1.13.99.1), i.e. myo-inositol oxygenase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y505/00—Intramolecular lyases (5.5)
    • C12Y505/01—Intramolecular lyases (5.5.1)
    • C12Y505/01004—Inositol-3-phosphate synthase (5.5.1.4)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
DK09755201.2T 2008-04-04 2009-04-03 Cellulær produktion af glucarsyre DK2274417T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4250208P 2008-04-04 2008-04-04
PCT/US2009/002111 WO2009145838A2 (en) 2008-04-04 2009-04-03 Cellular production of glucaric acid

Publications (1)

Publication Number Publication Date
DK2274417T3 true DK2274417T3 (da) 2013-10-28

Family

ID=41377836

Family Applications (1)

Application Number Title Priority Date Filing Date
DK09755201.2T DK2274417T3 (da) 2008-04-04 2009-04-03 Cellulær produktion af glucarsyre

Country Status (8)

Country Link
US (2) US8835147B2 (da)
EP (1) EP2274417B1 (da)
JP (2) JP6196016B2 (da)
KR (1) KR101625443B1 (da)
CN (1) CN102066552B (da)
CA (1) CA2720526C (da)
DK (1) DK2274417T3 (da)
WO (1) WO2009145838A2 (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI20086236A0 (fi) 2008-12-23 2008-12-23 Valtion Teknillinen Heksuronihapon konversio heksarihapoksi
EP2781600B1 (en) 2011-11-14 2019-08-28 Asahi Kasei Kabushiki Kaisha Method for producing myo-inositol and myo-inositol derivative
WO2013125509A1 (ja) 2012-02-24 2013-08-29 旭化成ケミカルズ株式会社 グルカル酸の製造方法
EP2850180A1 (en) * 2012-05-18 2015-03-25 Novozymes A/S Bacterial mutants with improved transformation efficiency
WO2013183610A1 (ja) 2012-06-04 2013-12-12 塩水港精糖株式会社 Ｄ－グルカル酸生産菌およびｄ－グルカル酸の製造方法
US9506090B2 (en) 2012-09-21 2016-11-29 Synthetic Genomics, Inc. Method for synthesizing FDCA and derivates thereof
US9528133B2 (en) 2012-09-21 2016-12-27 Synthetic Genomics, Inc. Compositions and methods for producing chemicals and derivatives thereof
EP3119899A4 (en) * 2014-03-21 2017-11-29 Synthetic Genomics, Inc. Compositions and methods for producing chemicals and derivatives thereof
US20170130210A1 (en) * 2014-06-09 2017-05-11 Massachusetts Institute Of Technology Dynamic knockdown of central metabolism for redirecting glucose-6-phosphate fluxes
CN104312934A (zh) * 2014-10-22 2015-01-28 江南大学 一种构建重组酵母生物合成葡萄糖醛酸的方法
CN104312935B (zh) * 2014-10-22 2018-07-06 江南大学 一种构建重组酵母发酵生产葡萄糖二酸的方法
WO2018004307A1 (ko) 2016-06-30 2018-01-04 씨제이제일제당 (주) 고농도 마이오-이노시톨의 효소적 제조방법
CN106148292B (zh) * 2016-07-06 2019-05-17 江南大学 一种肌醇加氧酶突变体及其应用
US11332723B2 (en) 2016-10-03 2022-05-17 The Regents Of The University Of California Engineered microorganisms for production of commodity chemicals and cellular biomass
FR3067350B1 (fr) 2017-06-12 2020-12-11 Seprosys Procede d'obtention d'une solution d'acide glucarique libre et solution obtenue
EP4071142B1 (en) 2017-06-22 2023-10-04 Archer Daniels Midland Company Process for making esters of 2,5-furandicarboxylic acid
CN107365806B (zh) * 2017-08-02 2020-04-03 南京师范大学 一种葡萄糖二酸的制备方法及其制备中的糖醛酸脱氢酶-nadh氧化酶和应用
CA3138481A1 (en) * 2019-05-17 2020-11-26 The Governing Council Of The University Of Toronto Enzymatic production of glucaric acid from glucuronic acid
CN110846436B (zh) * 2019-12-25 2021-09-28 江南大学 一种快速鉴别Ale和Lager型啤酒酵母的方法
CN110951794B (zh) * 2019-12-31 2022-03-25 江南大学 一种提高酿酒酵母工程菌生产葡萄糖二酸的发酵方法
CN111019852B (zh) * 2019-12-31 2021-11-23 江南大学 一种提高酿酒酵母工程菌株合成葡萄糖二酸效率的方法
KR102649855B1 (ko) * 2020-09-15 2024-03-22 경북대학교 산학협력단 갈락투론산을 발효하여 뮤식산을 생산하는 신규 효모 균주
BR112023019608A2 (pt) * 2021-03-26 2023-12-19 Archer Daniels Midland Co Método para produzir ácido 5-ceto-4-deoxi glucárico (kdg), método de produção de ácido furano dicarboxílico (fdca), enzima glucarato desidratase, método para obter uma glucarato desidratase mutante, e variante de glucarato desidratase
KR102626750B1 (ko) * 2021-12-27 2024-01-19 한국프라임제약주식회사 키로이노시톨 생성능이 우수한 락티카제이 바실러스 카제이 WiKim0135 균주 및 이의 혈당강하 용도

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US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5859205A (en) 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
DE19604798A1 (de) * 1996-02-09 1997-08-14 Herbstreith & Fox Kg Pektin Fa Herstellung von L-Ascorbinsäure
AU2002306764A1 (en) * 2001-03-19 2002-10-03 Cargill Incorporated Myo-inositol oxygenases

Also Published As

Publication number Publication date
CN102066552A (zh) 2011-05-18
JP6196016B2 (ja) 2017-09-13
EP2274417A2 (en) 2011-01-19
CA2720526C (en) 2017-11-28
EP2274417B1 (en) 2013-07-24
CN102066552B (zh) 2014-03-12
KR101625443B1 (ko) 2016-05-30
US20110124065A1 (en) 2011-05-26
WO2009145838A3 (en) 2010-02-18
EP2274417A4 (en) 2012-05-02
WO2009145838A2 (en) 2009-12-03
JP2017018140A (ja) 2017-01-26
US20150093794A1 (en) 2015-04-02
KR20110027652A (ko) 2011-03-16
JP2011516063A (ja) 2011-05-26
CA2720526A1 (en) 2009-12-03
BRPI0911171A2 (pt) 2015-08-04
US8835147B2 (en) 2014-09-16

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