JP2011509081A5 - - Google Patents
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- Publication number
- JP2011509081A5 JP2011509081A5 JP2010541103A JP2010541103A JP2011509081A5 JP 2011509081 A5 JP2011509081 A5 JP 2011509081A5 JP 2010541103 A JP2010541103 A JP 2010541103A JP 2010541103 A JP2010541103 A JP 2010541103A JP 2011509081 A5 JP2011509081 A5 JP 2011509081A5
- Authority
- JP
- Japan
- Prior art keywords
- rna
- gene
- sequence
- comoviridae
- mutated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000623 proteins and genes Proteins 0.000 claims 49
- 230000014509 gene expression Effects 0.000 claims 25
- 102000004169 proteins and genes Human genes 0.000 claims 25
- 241000723655 Cowpea mosaic virus Species 0.000 claims 19
- 241000961587 Secoviridae Species 0.000 claims 17
- 108700028146 Genetic Enhancer Elements Proteins 0.000 claims 11
- 238000000034 method Methods 0.000 claims 9
- 241000700605 Viruses Species 0.000 claims 7
- 241001493065 dsRNA viruses Species 0.000 claims 7
- 241000196324 Embryophyta Species 0.000 claims 6
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 6
- 239000002773 nucleotide Substances 0.000 claims 6
- 125000003729 nucleotide group Chemical group 0.000 claims 6
- 101150084101 RNA2 gene Proteins 0.000 claims 4
- 101100353432 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) PRP2 gene Proteins 0.000 claims 4
- 108020005345 3' Untranslated Regions Proteins 0.000 claims 3
- 241000723607 Comovirus Species 0.000 claims 3
- 230000003612 virological effect Effects 0.000 claims 3
- LMKYZBGVKHTLTN-NKWVEPMBSA-N D-nopaline Chemical compound NC(=N)NCCC[C@@H](C(O)=O)N[C@@H](C(O)=O)CCC(O)=O LMKYZBGVKHTLTN-NKWVEPMBSA-N 0.000 claims 2
- 108700026244 Open Reading Frames Proteins 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 230000030279 gene silencing Effects 0.000 claims 2
- 238000012226 gene silencing method Methods 0.000 claims 2
- 238000003786 synthesis reaction Methods 0.000 claims 2
- 238000011144 upstream manufacturing Methods 0.000 claims 2
- 108020004414 DNA Proteins 0.000 claims 1
- 241000238631 Hexapoda Species 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 230000002708 enhancing effect Effects 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0800272.7 | 2008-01-08 | ||
| GBGB0800272.7A GB0800272D0 (en) | 2008-01-08 | 2008-01-08 | Protein expression systems |
| PCT/GB2009/000060 WO2009087391A1 (en) | 2008-01-08 | 2009-01-08 | Protein expression systems |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011509081A JP2011509081A (ja) | 2011-03-24 |
| JP2011509081A5 true JP2011509081A5 (enExample) | 2012-02-23 |
| JP5745857B2 JP5745857B2 (ja) | 2015-07-08 |
Family
ID=39111256
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010541103A Expired - Fee Related JP5745857B2 (ja) | 2008-01-08 | 2009-01-08 | タンパク質発現系 |
Country Status (18)
| Country | Link |
|---|---|
| US (5) | US8674084B2 (enExample) |
| EP (1) | EP2240589B1 (enExample) |
| JP (1) | JP5745857B2 (enExample) |
| KR (1) | KR101602972B1 (enExample) |
| CN (1) | CN101952446B (enExample) |
| AU (1) | AU2009203608B2 (enExample) |
| BR (1) | BRPI0906509A2 (enExample) |
| CA (1) | CA2711895C (enExample) |
| DK (1) | DK2240589T3 (enExample) |
| ES (1) | ES2537198T3 (enExample) |
| GB (1) | GB0800272D0 (enExample) |
| IL (1) | IL206606A (enExample) |
| MX (1) | MX2010007336A (enExample) |
| NZ (1) | NZ586939A (enExample) |
| PT (1) | PT2240589E (enExample) |
| RU (1) | RU2539793C2 (enExample) |
| WO (1) | WO2009087391A1 (enExample) |
| ZA (1) | ZA201005245B (enExample) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2615372A1 (en) | 2007-07-13 | 2009-01-13 | Marc-Andre D'aoust | Influenza virus-like particles (vlps) comprising hemagglutinin |
| CN103122354B (zh) | 2007-11-27 | 2018-03-23 | 麦迪卡格公司 | 表达血凝素之转基因植物中生产的重组流感病毒样颗粒(vlp) |
| GB0800272D0 (en) | 2008-01-08 | 2008-02-13 | Plant Bioscience Ltd | Protein expression systems |
| US8771703B2 (en) | 2008-07-08 | 2014-07-08 | Medicago Inc. | Soluble recombinant influenza antigens |
| CA2762042C (en) | 2009-06-24 | 2012-11-20 | Medicago Inc. | Chimeric influenza virus-like particles comprising hemagglutinin |
| GB201002434D0 (en) * | 2010-02-12 | 2010-03-31 | Plant Bioscience Ltd | Non-infectious RNA source |
| US20130295609A1 (en) | 2010-11-04 | 2013-11-07 | Medicago Inc. | Plant expression system |
| WO2012098111A1 (en) | 2011-01-17 | 2012-07-26 | Philip Morris Products S.A. | Vectors for nucleic acid expression in plants |
| CA2824152C (en) | 2011-01-17 | 2022-12-13 | Philip Morris Products S.A. | Method and system for producing a heterologous polypeptide in a nicotiana tabacum plant |
| US11390878B2 (en) | 2011-09-30 | 2022-07-19 | Medicago Inc. | Increasing protein yield in plants |
| SI2760882T1 (sl) | 2011-09-30 | 2023-10-30 | Medicago Inc. | Povečanje količine virusom podobnih delcev v rastlinah |
| CN104010655B (zh) * | 2011-11-11 | 2018-06-22 | 菲利普莫里斯生产公司 | 普通烟草中产生的包含血凝素的流感病毒样颗粒(vlp) |
| AU2013312971B2 (en) | 2012-09-05 | 2019-04-18 | Medicago Inc. | Picornavirus-like particle production in plants |
| KR101449155B1 (ko) * | 2012-12-06 | 2014-10-13 | 주식회사 바이오앱 | 식물체에서 목적 단백질의 번역 효율을 증진시키기 위한 염기서열 |
| US12467058B2 (en) | 2013-03-28 | 2025-11-11 | Aramis Biotechnologies Inc. | Influenza virus-like particle production in plants |
| JP2016516415A (ja) | 2013-03-28 | 2016-06-09 | メディカゴ インコーポレイテッド | 植物におけるインフルエンザウイルス様粒子の生成 |
| EP3092309B1 (en) | 2014-01-10 | 2021-02-24 | Medicago Inc. | Cpmv enhancer elements |
| WO2015143567A1 (en) | 2014-03-27 | 2015-10-01 | Medicago Inc. | Modified cpmv enhancer elements |
| JP6788582B2 (ja) | 2014-07-11 | 2020-11-25 | メディカゴ インコーポレイテッド | 植物におけるタンパク質生産の改変 |
| EA201791683A1 (ru) | 2015-01-23 | 2017-12-29 | Медикаго Инк. | Получение ротавирусоподобных частиц в растениях |
| CN107920487A (zh) | 2015-07-02 | 2018-04-17 | 莫迪卡戈公司 | 茉莉酸通路激活剂 |
| WO2018144831A1 (en) * | 2017-02-02 | 2018-08-09 | Duke University | Compositions and methods for controlling gene expression |
| GB201721600D0 (en) | 2017-12-21 | 2018-02-07 | Plant Bioscience Ltd | Metabolic engineering |
| AU2019233860B2 (en) | 2018-03-14 | 2025-02-13 | Aramis Biotechnologies Inc. | Plant expression enhancer |
| GB201808617D0 (en) | 2018-05-25 | 2018-07-11 | Plant Bioscience Ltd | Scaffold modification |
| WO2020033416A1 (en) * | 2018-08-06 | 2020-02-13 | Northwestern University | Combined transcription and translation platform derived from plant chloroplasts |
| MX2021010974A (es) | 2019-03-14 | 2021-10-13 | Mitsubishi Tanabe Pharma Corp | Potenciador de la expresion de plantas endogenas. |
| GB201908431D0 (en) | 2019-06-12 | 2019-07-24 | Plant Bioscience Ltd | Biosynthetic genes and polypeptides |
| JP7517704B2 (ja) * | 2019-06-21 | 2024-07-17 | 国立大学法人大阪大学 | 外来遺伝子を安定的に保持する人工組換えｒｎａウイルスの作製方法 |
| GB201909104D0 (en) * | 2019-06-25 | 2019-08-07 | Plant Bioscience Ltd | Transferase enzymes |
| CN110468129B (zh) * | 2019-08-08 | 2023-03-24 | 四川农业大学 | 一种基于cmv rna2的体外干扰黄瓜花叶病的制剂、其制备方法与应用 |
| CN111777670B (zh) * | 2020-06-19 | 2021-07-30 | 东北农业大学 | 一种pH调节自组装抗菌肽及制备方法和应用 |
| EP4351320A1 (en) | 2021-06-09 | 2024-04-17 | ImmunityBio, Inc. | Methods and systems for producing a protein of interest in a plant |
| CN114181969B (zh) * | 2021-12-09 | 2024-05-28 | 苏州大学 | 一种制备包裹外源蛋白的多角体的方法 |
| GB202209501D0 (en) | 2022-06-29 | 2022-08-10 | Plant Bioscience Ltd | Biosynthetic enzymes |
| KR20250167005A (ko) | 2023-04-03 | 2025-11-28 | 스위프트파마 비브이 | 식물에서 고효율 이종성 유전자 발현을 위한 트랜스-상보성 벡터 시스템 |
| KR20250082120A (ko) * | 2023-11-29 | 2025-06-09 | 서강대학교산학협력단 | 검은눈콩 모자이크 바이러스의 바이러스 유사 입자의 제조방법 및 이의 활용 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19701141C1 (de) * | 1997-01-16 | 1998-04-09 | Hoechst Ag | Genkonstrukte für durch Proteasen aktivierbare Wirksubstanzen |
| WO2001096569A1 (en) | 2000-06-13 | 2001-12-20 | The University Of Queensland | Expression modulating sequences |
| WO2007135480A1 (en) | 2006-05-22 | 2007-11-29 | Plant Bioscience Limited | Bipartite system, method and composition for the constitutive and inducible expression of high levels of foreign proteins in plants |
| GB0800272D0 (en) | 2008-01-08 | 2008-02-13 | Plant Bioscience Ltd | Protein expression systems |
| EP3092309B1 (en) | 2014-01-10 | 2021-02-24 | Medicago Inc. | Cpmv enhancer elements |
| WO2015143567A1 (en) | 2014-03-27 | 2015-10-01 | Medicago Inc. | Modified cpmv enhancer elements |
-
2008
- 2008-01-08 GB GBGB0800272.7A patent/GB0800272D0/en not_active Ceased
-
2009
- 2009-01-08 JP JP2010541103A patent/JP5745857B2/ja not_active Expired - Fee Related
- 2009-01-08 BR BRPI0906509A patent/BRPI0906509A2/pt not_active Application Discontinuation
- 2009-01-08 WO PCT/GB2009/000060 patent/WO2009087391A1/en not_active Ceased
- 2009-01-08 CA CA2711895A patent/CA2711895C/en active Active
- 2009-01-08 AU AU2009203608A patent/AU2009203608B2/en not_active Ceased
- 2009-01-08 NZ NZ586939A patent/NZ586939A/xx not_active IP Right Cessation
- 2009-01-08 EP EP09700649.8A patent/EP2240589B1/en active Active
- 2009-01-08 US US12/812,165 patent/US8674084B2/en active Active
- 2009-01-08 MX MX2010007336A patent/MX2010007336A/es active IP Right Grant
- 2009-01-08 ES ES09700649.8T patent/ES2537198T3/es active Active
- 2009-01-08 CN CN200980105869.XA patent/CN101952446B/zh active Active
- 2009-01-08 KR KR1020107017609A patent/KR101602972B1/ko not_active Expired - Fee Related
- 2009-01-08 PT PT97006498T patent/PT2240589E/pt unknown
- 2009-01-08 RU RU2010133217/10A patent/RU2539793C2/ru not_active Application Discontinuation
- 2009-01-08 DK DK09700649T patent/DK2240589T3/en active
-
2010
- 2010-06-24 IL IL206606A patent/IL206606A/en active IP Right Grant
- 2010-07-22 ZA ZA2010/05245A patent/ZA201005245B/en unknown
-
2014
- 2014-02-04 US US14/172,301 patent/US20140250549A1/en not_active Abandoned
-
2017
- 2017-08-11 US US15/674,881 patent/US10822613B2/en not_active Expired - Fee Related
-
2020
- 2020-08-31 US US17/007,242 patent/US10947549B2/en active Active
- 2020-09-09 US US17/016,191 patent/US20210155947A1/en not_active Abandoned
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