JP2011507929A5 - - Google Patents

Download PDF

Info

Publication number
JP2011507929A5
JP2011507929A5 JP2010540098A JP2010540098A JP2011507929A5 JP 2011507929 A5 JP2011507929 A5 JP 2011507929A5 JP 2010540098 A JP2010540098 A JP 2010540098A JP 2010540098 A JP2010540098 A JP 2010540098A JP 2011507929 A5 JP2011507929 A5 JP 2011507929A5
Authority
JP
Japan
Prior art keywords
group
alkyl
same
different
iii
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010540098A
Other languages
English (en)
Japanese (ja)
Other versions
JP5698985B2 (ja
JP2011507929A (ja
Filing date
Publication date
Priority claimed from EP07425830A external-priority patent/EP2078711A1/en
Application filed filed Critical
Publication of JP2011507929A publication Critical patent/JP2011507929A/ja
Publication of JP2011507929A5 publication Critical patent/JP2011507929A5/ja
Application granted granted Critical
Publication of JP5698985B2 publication Critical patent/JP5698985B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2010540098A 2007-12-28 2008-12-16 ５位置換アザインドール誘導体，それを含む医薬組成物，中間化合物及びその製造方法 Expired - Fee Related JP5698985B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07425830.2 2007-12-28
EP07425830A EP2078711A1 (en) 2007-12-28 2007-12-28 (Aza)indole derivative substituted in position 5, pharmaceutical composition comprising it, intermediate compounds and preparation process therefor
PCT/EP2008/067622 WO2009083436A1 (en) 2007-12-28 2008-12-16 (aza)indole derivative substituted in position 5, pharmaceutical composition comprising it, intermediate compounds and preparation process therefor

Publications (3)

Publication Number Publication Date
JP2011507929A JP2011507929A (ja) 2011-03-10
JP2011507929A5 true JP2011507929A5 (enExample) 2014-01-23
JP5698985B2 JP5698985B2 (ja) 2015-04-08

Family

ID=39167787

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010540098A Expired - Fee Related JP5698985B2 (ja) 2007-12-28 2008-12-16 ５位置換アザインドール誘導体，それを含む医薬組成物，中間化合物及びその製造方法

Country Status (20)

Country Link
US (2) US8399477B2 (enExample)
EP (3) EP2078711A1 (enExample)
JP (1) JP5698985B2 (enExample)
KR (2) KR101671874B1 (enExample)
CN (1) CN101910127B (enExample)
AR (1) AR069961A1 (enExample)
AU (1) AU2008342705B2 (enExample)
BR (1) BRPI0821450A2 (enExample)
CA (1) CA2707339C (enExample)
DK (2) DK2234968T3 (enExample)
EA (1) EA020373B1 (enExample)
ES (2) ES2523167T3 (enExample)
GE (1) GEP20125547B (enExample)
IL (1) IL206062A (enExample)
PL (2) PL2444392T3 (enExample)
PT (2) PT2234968E (enExample)
SG (1) SG187400A1 (enExample)
SI (2) SI2444392T1 (enExample)
UA (1) UA100867C2 (enExample)
WO (1) WO2009083436A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101365824B1 (ko) 2010-10-22 2014-02-20 엘지디스플레이 주식회사 유기전계발광소자
SI3102576T1 (sl) 2014-02-03 2019-08-30 Vitae Pharmaceuticals, Llc Inhibitorji dihidropirolopiridina ROR-gama
CN105636951B (zh) * 2014-04-14 2018-05-15 上海恒瑞医药有限公司 酰胺类衍生物及其可药用盐、其制备方法及其在医药上的应用
US9663515B2 (en) 2014-11-05 2017-05-30 Vitae Pharmaceuticals, Inc. Dihydropyrrolopyridine inhibitors of ROR-gamma
ES2856931T3 (es) * 2015-08-05 2021-09-28 Vitae Pharmaceuticals Llc Moduladores de ROR-gamma
WO2017087608A1 (en) 2015-11-20 2017-05-26 Vitae Pharmaceuticals, Inc. Modulators of ror-gamma
TWI757266B (zh) 2016-01-29 2022-03-11 美商維它藥物有限責任公司 ＲＯＲ－γ調節劑
CN107033026A (zh) * 2017-06-07 2017-08-11 李博强 一种对硝基苯肼盐酸盐的制备方法
WO2019018975A1 (en) 2017-07-24 2019-01-31 Vitae Pharmaceuticals, Inc. INHIBITORS OF ROR GAMMA
KR20200053481A (ko) 2017-07-24 2020-05-18 비타이 파마슈티컬즈, 엘엘씨 RORγ의 억제제
WO2021040393A1 (ko) * 2019-08-26 2021-03-04 국제약품 주식회사 인돌 카복사미드 유도체 및 그를 포함하는 약제학적 조성물
CN114605303A (zh) * 2022-03-14 2022-06-10 武汉工程大学 一种地拉韦啶及其中间体的合成方法
CN119019389A (zh) * 2024-06-05 2024-11-26 四川大学 7-氮杂吲哚类化合物及其合成方法和用途
CN119101040B (zh) * 2024-11-08 2025-03-21 杭州澳赛诺医药技术有限公司 一种通过去对称化合成芳基取代的手性四氢吡喃环的方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2354766A1 (fr) * 1976-06-17 1978-01-13 Labaz Derives n-aminoalkyles d'indole et procedes pour les preparer
US6114532A (en) * 1998-02-03 2000-09-05 Boehringer Ingelheim Pharma Kg Bicyclic heterocycles, the preparation thereof, and their use as pharmaceuticals
AU2720199A (en) * 1998-02-03 1999-08-23 Boehringer Ingelheim Pharma Kg Five-membered, benzo-condensed heterocycles used as antithrombotic agents
DE19834751A1 (de) * 1998-08-01 2000-02-03 Boehringer Ingelheim Pharma Disubstituierte bicyclische Heterocyclen, ihre Herstellung und ihre Verwendung als Arzneimittel
WO2001070743A1 (en) * 2000-03-20 2001-09-27 Axys Pharmaceuticals, Inc. Non-amidine containing protease inhibitors
US20020052373A1 (en) * 2000-10-26 2002-05-02 Zorn Stevin H. Combination treatment for dementia or cognitive deficits associated with alzheimer's disease and parkinson's disease
IL140096A0 (en) * 2000-12-05 2002-02-10 Internat Specialty Products Is Process for preparation of zafirlukast
DE10147672A1 (de) * 2001-09-27 2003-04-10 Bayer Ag Substituierte 2,5-Diamidoindole und ihre Verwendung
EP1578418A2 (en) * 2002-12-20 2005-09-28 Bayer HealthCare AG Use of substituted 2,5-diamidoindoles for the treatment of urological diseases
SE0300908D0 (sv) * 2003-03-31 2003-03-31 Astrazeneca Ab Azaindole derivatives, preparations thereof, uses thereof and compositions containing them
CN101087787A (zh) 2004-12-23 2007-12-12 霍夫曼-拉罗奇有限公司 苯甲酰胺衍生物，它们的制备及作为药剂的应用
JP2009511559A (ja) * 2005-10-12 2009-03-19 バイオリポックス エービー 炎症の治療に有用なベンゾオキサゾール類
NZ596889A (en) * 2006-04-07 2013-06-28 Vertex Pharma Use of amide indole derivatives as modulators of ATP-binding cassette transporters
JP2008006663A (ja) * 2006-06-28 2008-01-17 Pilot Ink Co Ltd 出没式筆記具
ITMI20061368A1 (it) * 2006-07-14 2008-01-15 Acraf Composto 2-arilindolico sostituito in posizione 5, composizione farmaceutica che lo comprende nonche' composti intermedi e procedimento per prepararlo

Similar Documents

Publication Publication Date Title
JP2011507929A5 (enExample)
WO2008115098A3 (fr) 2,3,4,5-tétrahydro-1h-pyrido[4,3-b]indoles substitués ainsi que procédés de leur fabrication et leur utilisation
NO20072371L (no) Kinuklidinderivater og deres anvendelse som muskarine M3-reseptorantagonister
JP2006528621A5 (enExample)
NO20080738L (no) Fremgangsmater for neurobeskyttelse
NZ231631A (en) Heterocyclically-substituted piperazine and diazepine derivatives and anxiolytic compositions
JP2008530099A5 (enExample)
WO2008035381A3 (en) Process for the preparation of amine derivatives as calcimimetics
NZ561747A (en) (Pyrrol-2-ylmethyl)-indol-1-yl-acetic acid derivatives with PGD2 antagonist activity
JP2010540593A5 (enExample)
MX2008000115A (es) Derivados de piperidina utiles como antagonistas de histamina h3.
PL164480B1 (pl) Sposób wytwarzania nowych pochodnych aminofenolu PL
JP2005505618A5 (enExample)
MX2009003927A (es) Derivado espirocetal de tioglucosa y uso del mismo como un agente terapeutico para la diabetes.
WO2008101935A3 (fr) Nouveaux composés dérivés d'indole et compositions pharmaceutiques les contenant
WO2004020430A3 (fr) Derives de dioxane-2-alkylcarbamates, leur preparation et leur application en therapeutique
JP2008546770A5 (enExample)
JP2009525312A5 (enExample)
MX2011009700A (es) Derivado de amida.
WO2007042912A3 (en) Heterocyclic compounds as pstat3/il-6 inhibitors
JP2006511498A5 (enExample)
JPH01268679A (ja) １―シクロプロピル―キノロンカルボン酸及びその誘導体の製造方法
CZ265994A3 (en) Derivatives of 1-/2h-1-benzopyran-2-on-8-yl/piperazine, process of their preparation pharmaceutical compositions containing thereof as active components and their use
NO20063330L (no) Amidderivater med en syklopropylaminokarbonylsubstituent som er nyttige som cytokininhibitorer
JP2011510026A5 (enExample)