JP2011503063A5 - - Google Patents
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- Publication number
- JP2011503063A5 JP2011503063A5 JP2010533098A JP2010533098A JP2011503063A5 JP 2011503063 A5 JP2011503063 A5 JP 2011503063A5 JP 2010533098 A JP2010533098 A JP 2010533098A JP 2010533098 A JP2010533098 A JP 2010533098A JP 2011503063 A5 JP2011503063 A5 JP 2011503063A5
- Authority
- JP
- Japan
- Prior art keywords
- medicament
- cancer
- compound
- pharmaceutically acceptable
- leukemia
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US258307P | 2007-11-08 | 2007-11-08 | |
| US61/002,583 | 2007-11-08 | ||
| US580307P | 2007-12-07 | 2007-12-07 | |
| US61/005,803 | 2007-12-07 | ||
| US9867608P | 2008-09-19 | 2008-09-19 | |
| US61/098,676 | 2008-09-19 | ||
| US11206008P | 2008-11-06 | 2008-11-06 | |
| US61/112,060 | 2008-11-06 | ||
| PCT/US2008/012539 WO2009061446A1 (en) | 2007-11-08 | 2008-11-07 | Methods of administering n-(5-tert-butyl-isoxazol-3-yl)-n'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea to treat proliferative disease |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014120238A Division JP2014221765A (ja) | 2007-11-08 | 2014-06-11 | 増殖性疾患を治療するための、Ｎ−（５−ｔｅｒｔ−ブチル−イソキサゾール−３−イル）−Ｎ’−｛４−［７−（２−モルホリン−４−イル−エトキシ）イミダゾ［２，ｌ−ｂ］［ｌ，３］ベンゾチアゾール−２−イル］フェニル｝尿素の投与方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011503063A JP2011503063A (ja) | 2011-01-27 |
| JP2011503063A5 true JP2011503063A5 (https=) | 2011-12-22 |
| JP5645667B2 JP5645667B2 (ja) | 2014-12-24 |
Family
ID=40262072
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010533098A Active JP5645667B2 (ja) | 2007-11-08 | 2008-11-07 | 増殖性疾患を治療するための、Ｎ−（５−ｔｅｒｔ−ブチル−イソキサゾール−３−イル）−Ｎ’−｛４−［７−（２−モルホリン−４−イル−エトキシ）イミダゾ［２，ｌ−ｂ］［ｌ，３］ベンゾチアゾール−２−イル］フェニル｝尿素の投与方法 |
| JP2014120238A Pending JP2014221765A (ja) | 2007-11-08 | 2014-06-11 | 増殖性疾患を治療するための、Ｎ−（５−ｔｅｒｔ−ブチル−イソキサゾール−３−イル）−Ｎ’−｛４−［７−（２−モルホリン−４−イル−エトキシ）イミダゾ［２，ｌ−ｂ］［ｌ，３］ベンゾチアゾール−２−イル］フェニル｝尿素の投与方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014120238A Pending JP2014221765A (ja) | 2007-11-08 | 2014-06-11 | 増殖性疾患を治療するための、Ｎ−（５−ｔｅｒｔ−ブチル−イソキサゾール−３−イル）−Ｎ’−｛４−［７−（２−モルホリン−４−イル−エトキシ）イミダゾ［２，ｌ−ｂ］［ｌ，３］ベンゾチアゾール−２−イル］フェニル｝尿素の投与方法 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US7968543B2 (https=) |
| EP (2) | EP2596795A1 (https=) |
| JP (2) | JP5645667B2 (https=) |
| KR (2) | KR101578481B1 (https=) |
| CN (1) | CN101835472A (https=) |
| AR (1) | AR069244A1 (https=) |
| AU (1) | AU2008325141B2 (https=) |
| CA (1) | CA2696807C (https=) |
| CY (1) | CY1114853T1 (https=) |
| DK (1) | DK2205244T3 (https=) |
| ES (1) | ES2436266T3 (https=) |
| HR (1) | HRP20131083T1 (https=) |
| MX (1) | MX2010002396A (https=) |
| PL (1) | PL2205244T3 (https=) |
| PT (1) | PT2205244E (https=) |
| SI (1) | SI2205244T1 (https=) |
| TW (1) | TW200924756A (https=) |
| WO (1) | WO2009061446A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2422890T3 (es) * | 2006-03-17 | 2013-09-16 | Ambit Biosciences Corporation | Compuestos de imidazolotiazol para el tratamiento de enfermedades proliferativas |
| CA2696776C (en) * | 2007-09-19 | 2015-12-15 | Ambit Biosciences Corporation | Solid forms comprising n-(5-tert-butyl-isoxazol-3-yl)-n'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea, compositions thereof, and uses therewith |
| CN102438588B (zh) | 2009-03-23 | 2015-04-01 | 埃姆比特生物科学公司 | 使用联合治疗法治疗疾病的方法 |
| SMT202000092T1 (it) * | 2009-05-14 | 2020-05-08 | Ambit Biosciences Corp | Formulazione essiccata a spruzzo o liofilizzata di ac220 |
| CN104447801A (zh) | 2009-11-05 | 2015-03-25 | 埃姆比特生物科学公司 | 用于制备咪唑并[2,1-b][1,3]苯并噻唑衍生物的方法 |
| US9109227B2 (en) | 2010-01-05 | 2015-08-18 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | FLT3 receptor antagonists for the treatment or the prevention of pain disorders |
| UY33472A (es) | 2010-06-30 | 2012-01-31 | Novartis Ag | ?composiciones farmacéuticas que comprenden monohidrato de lactato de 4-amino-5-fluoro-3-[6-(4-metil-piperazin-1-il)-1hbencimidazol-2-il]-1h-quinolin-2-ona?. |
| CN103172648B (zh) * | 2011-12-20 | 2016-05-25 | 上海迪诺医药科技有限公司 | 三杂环衍生物、制备方法及应用 |
| JP6116847B2 (ja) * | 2012-10-01 | 2017-04-19 | アムビト バイオサイエンシス コーポレーションＡｍｂｉｔ Ｂｉｏｓｃｉｅｎｃｅｓ Ｃｏｒｐｏｒａｔｉｏｎ | シクロデキストリンとの混合体を含有する錠剤 |
| CN104513252B (zh) * | 2013-09-26 | 2017-11-10 | 广东东阳光药业有限公司 | 取代脲衍生物及其在药物中的应用 |
| CN107001283B (zh) | 2014-07-31 | 2021-05-25 | 国家健康与医学研究院 | Flt3受体拮抗剂 |
| KR20250025516A (ko) | 2014-12-22 | 2025-02-21 | 젠자임 코포레이션 | 포유류 세포의 배양 방법 |
| JP6564449B2 (ja) | 2015-02-20 | 2019-08-21 | 第一三共株式会社 | がんの併用治療法 |
| EP3269367B1 (en) * | 2015-03-11 | 2020-10-07 | Riken | Therapeutic agent for intractable leukemia |
| EP3254698A1 (en) | 2016-06-08 | 2017-12-13 | Universite De Montpellier | Flt3 receptor inhibitor at low dosage for the treatment of neuropathic pain |
| WO2018211018A1 (en) | 2017-05-17 | 2018-11-22 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Flt3 inhibitors for improving pain treatments by opioids |
| WO2021138391A1 (en) | 2019-12-30 | 2021-07-08 | Tyra Biosciences, Inc. | Indazole compounds |
| WO2021180008A1 (zh) * | 2020-03-11 | 2021-09-16 | 暨南大学 | 含脲结构的三芳环化合物及其应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US233906A (en) * | 1880-11-02 | Combined stirrer and thermometer | ||
| US233903A (en) * | 1880-11-02 | Velocipede | ||
| US994635A (en) * | 1911-01-10 | 1911-06-06 | Harry C Buhoup | Car-truck. |
| US4328245A (en) | 1981-02-13 | 1982-05-04 | Syntex (U.S.A.) Inc. | Carbonate diester solutions of PGE-type compounds |
| US4410545A (en) | 1981-02-13 | 1983-10-18 | Syntex (U.S.A.) Inc. | Carbonate diester solutions of PGE-type compounds |
| US4409239A (en) | 1982-01-21 | 1983-10-11 | Syntex (U.S.A.) Inc. | Propylene glycol diester solutions of PGE-type compounds |
| US6267985B1 (en) * | 1999-06-30 | 2001-07-31 | Lipocine Inc. | Clear oil-containing pharmaceutical compositions |
| ES2422890T3 (es) | 2006-03-17 | 2013-09-16 | Ambit Biosciences Corporation | Compuestos de imidazolotiazol para el tratamiento de enfermedades proliferativas |
| CA2696776C (en) * | 2007-09-19 | 2015-12-15 | Ambit Biosciences Corporation | Solid forms comprising n-(5-tert-butyl-isoxazol-3-yl)-n'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea, compositions thereof, and uses therewith |
-
2008
- 2008-11-07 CA CA2696807A patent/CA2696807C/en active Active
- 2008-11-07 KR KR1020107006419A patent/KR101578481B1/ko active Active
- 2008-11-07 PT PT88471131T patent/PT2205244E/pt unknown
- 2008-11-07 EP EP12197285.5A patent/EP2596795A1/en not_active Withdrawn
- 2008-11-07 SI SI200831093T patent/SI2205244T1/sl unknown
- 2008-11-07 HR HRP20131083AT patent/HRP20131083T1/hr unknown
- 2008-11-07 MX MX2010002396A patent/MX2010002396A/es active IP Right Grant
- 2008-11-07 KR KR1020157024194A patent/KR20150105494A/ko not_active Ceased
- 2008-11-07 PL PL08847113T patent/PL2205244T3/pl unknown
- 2008-11-07 TW TW097143281A patent/TW200924756A/zh unknown
- 2008-11-07 AR ARP080104899A patent/AR069244A1/es unknown
- 2008-11-07 DK DK08847113.1T patent/DK2205244T3/da active
- 2008-11-07 CN CN200880112433A patent/CN101835472A/zh active Pending
- 2008-11-07 WO PCT/US2008/012539 patent/WO2009061446A1/en not_active Ceased
- 2008-11-07 US US12/267,321 patent/US7968543B2/en active Active
- 2008-11-07 ES ES08847113T patent/ES2436266T3/es active Active
- 2008-11-07 JP JP2010533098A patent/JP5645667B2/ja active Active
- 2008-11-07 AU AU2008325141A patent/AU2008325141B2/en active Active
- 2008-11-07 EP EP08847113.1A patent/EP2205244B1/en active Active
-
2013
- 2013-11-21 CY CY20131101036T patent/CY1114853T1/el unknown
-
2014
- 2014-06-11 JP JP2014120238A patent/JP2014221765A/ja active Pending
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