|
US202587A
(en)
*
|
|
1878-04-16 |
|
Improvement in door-hangers |
|
US36107A
(en)
*
|
|
1862-08-05 |
|
Improvement in |
|
US12758A
(en)
*
|
|
1855-04-24 |
|
chane |
|
GB1268212A
(en)
*
|
1968-04-19 |
1972-03-22 |
Zaidan Hojin Biseibutsu |
Tripeptide derivatives
|
|
JPS6050743B2
(ja)
*
|
1976-06-02 |
1985-11-09 |
旭光学工業株式会社 |
アパタイト焼結体及びその製造方法
|
|
US4272398A
(en)
*
|
1978-08-17 |
1981-06-09 |
The United States Of America As Represented By The Secretary Of Agriculture |
Microencapsulation process
|
|
US4376110A
(en)
|
1980-08-04 |
1983-03-08 |
Hybritech, Incorporated |
Immunometric assays using monoclonal antibodies
|
|
US5155020A
(en)
|
1989-03-08 |
1992-10-13 |
Health Research Inc. |
Recombinant poxvirus host range selection system
|
|
US4769330A
(en)
|
1981-12-24 |
1988-09-06 |
Health Research, Incorporated |
Modified vaccinia virus and methods for making and using the same
|
|
CH652145A5
(de)
|
1982-01-22 |
1985-10-31 |
Sandoz Ag |
Verfahren zur in vitro-herstellung von hybridomen welche humane monoklonale antikoerper erzeugen.
|
|
US4650764A
(en)
|
1983-04-12 |
1987-03-17 |
Wisconsin Alumni Research Foundation |
Helper cell
|
|
US4634666A
(en)
*
|
1984-01-06 |
1987-01-06 |
The Board Of Trustees Of The Leland Stanford Junior University |
Human-murine hybridoma fusion partner
|
|
US5225539A
(en)
*
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US4861719A
(en)
*
|
1986-04-25 |
1989-08-29 |
Fred Hutchinson Cancer Research Center |
DNA constructs for retrovirus packaging cell lines
|
|
US4925673A
(en)
*
|
1986-08-18 |
1990-05-15 |
Clinical Technologies Associates, Inc. |
Delivery systems for pharmacological agents encapsulated with proteinoids
|
|
US5260203A
(en)
*
|
1986-09-02 |
1993-11-09 |
Enzon, Inc. |
Single polypeptide chain binding molecules
|
|
US4946778A
(en)
*
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
|
US4704692A
(en)
|
1986-09-02 |
1987-11-03 |
Ladner Robert C |
Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides
|
|
EP0832981A1
(en)
|
1987-02-17 |
1998-04-01 |
Pharming B.V. |
DNA sequences to target proteins to the mammary gland for efficient secretion
|
|
US4853871A
(en)
|
1987-04-06 |
1989-08-01 |
Genex Corporation |
Computer-based method for designing stablized proteins
|
|
US4980289A
(en)
*
|
1987-04-27 |
1990-12-25 |
Wisconsin Alumni Research Foundation |
Promoter deficient retroviral vector
|
|
US4861627A
(en)
*
|
1987-05-01 |
1989-08-29 |
Massachusetts Institute Of Technology |
Preparation of multiwall polymeric microcapsules
|
|
US5278056A
(en)
*
|
1988-02-05 |
1994-01-11 |
The Trustees Of Columbia University In The City Of New York |
Retroviral packaging cell lines and process of using same
|
|
US4891719A
(en)
*
|
1988-10-03 |
1990-01-02 |
Datatape Incorporated |
Fast closure method for a data signal channel
|
|
IL162181A
(en)
|
1988-12-28 |
2006-04-10 |
Pdl Biopharma Inc |
A method of producing humanized immunoglubulin, and polynucleotides encoding the same
|
|
US5530101A
(en)
*
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5124263A
(en)
*
|
1989-01-12 |
1992-06-23 |
Wisconsin Alumni Research Foundation |
Recombination resistant retroviral helper cell and products produced thereby
|
|
US5225336A
(en)
|
1989-03-08 |
1993-07-06 |
Health Research Incorporated |
Recombinant poxvirus host range selection system
|
|
US5175099A
(en)
|
1989-05-17 |
1992-12-29 |
Research Corporation Technologies, Inc. |
Retrovirus-mediated secretion of recombinant products
|
|
US5240846A
(en)
|
1989-08-22 |
1993-08-31 |
The Regents Of The University Of Michigan |
Gene therapy vector for cystic fibrosis
|
|
US5013556A
(en)
|
1989-10-20 |
1991-05-07 |
Liposome Technology, Inc. |
Liposomes with enhanced circulation time
|
|
US5633076A
(en)
*
|
1989-12-01 |
1997-05-27 |
Pharming Bv |
Method of producing a transgenic bovine or transgenic bovine embryo
|
|
DE69133566T2
(de)
|
1990-01-12 |
2007-12-06 |
Amgen Fremont Inc. |
Bildung von xenogenen Antikörpern
|
|
US5283173A
(en)
*
|
1990-01-24 |
1994-02-01 |
The Research Foundation Of State University Of New York |
System to detect protein-protein interactions
|
|
US5204243A
(en)
*
|
1990-02-14 |
1993-04-20 |
Health Research Incorporated |
Recombinant poxvirus internal cores
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
AU665190B2
(en)
|
1990-07-10 |
1995-12-21 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
|
KR100272077B1
(ko)
*
|
1990-08-29 |
2000-11-15 |
젠팜인터내셔날,인코포레이티드 |
이종 항체를 생산할 수 있는 전이유전자를 가진 인간이외의 동물
|
|
US5877397A
(en)
|
1990-08-29 |
1999-03-02 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5545806A
(en)
*
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5661016A
(en)
*
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5770429A
(en)
*
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5789650A
(en)
*
|
1990-08-29 |
1998-08-04 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5625126A
(en)
*
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5874299A
(en)
|
1990-08-29 |
1999-02-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5633425A
(en)
*
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
JP3507486B2
(ja)
|
1991-03-15 |
2004-03-15 |
アムジエン・インコーポレーテツド |
顆粒球コロニー刺激因子の肺内投与
|
|
DE69230142T2
(de)
*
|
1991-05-15 |
2000-03-09 |
Cambridge Antibody Technology Ltd. |
Verfahren zur herstellung von spezifischen bindungspaargliedern
|
|
US5858657A
(en)
|
1992-05-15 |
1999-01-12 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
|
US5120727A
(en)
|
1991-05-29 |
1992-06-09 |
American Home Products Corporation |
Rapamycin dimers
|
|
DE69228606T2
(de)
|
1991-07-03 |
1999-06-24 |
Kanebo, Ltd., Tokio/Tokyo |
Verfahren und vorrichtung zur herstellung eines thermoplastischen polyurethan-elastomers
|
|
US5202332A
(en)
|
1991-08-07 |
1993-04-13 |
American Home Products Corporation |
Rapamycin analog as immunosuppressant
|
|
US5162333A
(en)
*
|
1991-09-11 |
1992-11-10 |
American Home Products Corporation |
Aminodiesters of rapamycin
|
|
US5565332A
(en)
|
1991-09-23 |
1996-10-15 |
Medical Research Council |
Production of chimeric antibodies - a combinatorial approach
|
|
US5932448A
(en)
*
|
1991-11-29 |
1999-08-03 |
Protein Design Labs., Inc. |
Bispecific antibody heterodimers
|
|
US5733743A
(en)
*
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
|
NZ251628A
(en)
|
1992-03-30 |
1996-07-26 |
American Home Prod |
Aqueous insectable rapamycin solution; product containing concentrate and diluent solutions
|
|
US5489680A
(en)
|
1992-10-13 |
1996-02-06 |
American Home Products Corporation |
Carbamates of rapamycin
|
|
US5434260A
(en)
|
1992-10-13 |
1995-07-18 |
American Home Products Corporation |
Carbamates of rapamycin
|
|
EP0672142B1
(en)
|
1992-12-04 |
2001-02-28 |
Medical Research Council |
Multivalent and multispecific binding proteins, their manufacture and use
|
|
DE4301681C1
(de)
*
|
1993-01-22 |
1994-10-20 |
Deutsche Aerospace Airbus |
Rohrverzweigung zwischen einer Luftleitung und einer Luftdusche
|
|
US5387680A
(en)
|
1993-08-10 |
1995-02-07 |
American Home Products Corporation |
C-22 ring stabilized rapamycin derivatives
|
|
EP0735893B1
(en)
|
1993-09-14 |
2008-11-26 |
Pharmexa Inc. |
Pan dr-binding peptides for enhancement of the immune response
|
|
AU689153B2
(en)
|
1993-11-08 |
1998-03-26 |
Cressy, Wayne Malcolm |
Head restraining device
|
|
US5385908A
(en)
*
|
1993-11-22 |
1995-01-31 |
American Home Products Corporation |
Hindered esters of rapamycin
|
|
SG64372A1
(en)
|
1993-12-17 |
1999-04-27 |
Novartis Ag |
Rapamycin derivatives
|
|
US5827690A
(en)
|
1993-12-20 |
1998-10-27 |
Genzyme Transgenics Corporatiion |
Transgenic production of antibodies in milk
|
|
US5877218A
(en)
*
|
1994-01-10 |
1999-03-02 |
Teva Pharmaceutical Industries, Ltd. |
Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives
|
|
US5362735A
(en)
|
1994-02-23 |
1994-11-08 |
Smithkline Beecham Corporation |
Rapamycin derivatives
|
|
US5451569A
(en)
*
|
1994-04-19 |
1995-09-19 |
Hong Kong University Of Science And Technology R & D Corporation Limited |
Pulmonary drug delivery system
|
|
US5731168A
(en)
*
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
EP1281718A3
(en)
|
1995-11-10 |
2005-01-19 |
ELAN CORPORATION, Plc |
Peptides which enhance transport across tissues
|
|
US5780462A
(en)
*
|
1995-12-27 |
1998-07-14 |
American Home Products Corporation |
Water soluble rapamycin esters
|
|
DE69707033T2
(de)
*
|
1996-03-05 |
2002-02-14 |
Hitachi, Ltd. |
Verfahren zur Behandlung von Gasen die Organohalogenzusammensetzungen enthalten
|
|
AUPO390396A0
(en)
|
1996-11-29 |
1996-12-19 |
Csl Limited |
Novel promiscuous T helper cell epitopes
|
|
US5989591A
(en)
|
1997-03-14 |
1999-11-23 |
American Home Products Corporation |
Rapamycin formulations for oral administration
|
|
US6982323B1
(en)
*
|
1997-12-23 |
2006-01-03 |
Alexion Pharmaceuticals, Inc. |
Chimeric proteins for diagnosis and treatment of diabetes
|
|
IL139686A0
(en)
|
1998-06-02 |
2002-02-10 |
Genentech Inc |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
GB9814640D0
(en)
|
1998-07-06 |
1998-09-02 |
Fujisawa Pharmaceutical Co |
New use
|
|
US6015809A
(en)
|
1998-08-17 |
2000-01-18 |
American Home Products Corporation |
Photocyclized rapamycin
|
|
CA2341142A1
(en)
|
1998-09-02 |
2000-03-09 |
Diadexus Llc |
A novel method of diagnosing, monitoring, staging, imaging and treating various cancers
|
|
US6468546B1
(en)
|
1998-12-17 |
2002-10-22 |
Corixa Corporation |
Compositions and methods for therapy and diagnosis of ovarian cancer
|
|
US6962980B2
(en)
|
1999-09-24 |
2005-11-08 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US7109292B2
(en)
|
1999-03-08 |
2006-09-19 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
WO2001001137A1
(en)
*
|
1999-06-30 |
2001-01-04 |
Children's Medical Center Corporation |
Fusion protein and uses thereof
|
|
DE19937656A1
(de)
*
|
1999-08-13 |
2001-02-15 |
Aventis Behring Gmbh |
Verwendung von Antithrombin III zur Prophylaxe und Therapie von Erkrankungen
|
|
AU2001273194A1
(en)
|
2000-06-30 |
2002-01-14 |
Amgen Inc. |
B7-Like Molecules and Uses Thereof
|
|
US6537968B1
(en)
*
|
2000-07-24 |
2003-03-25 |
Alphamed Pharmaceuticals Corp |
Treatment of lupus erythematosus
|
|
WO2002010187A1
(en)
*
|
2000-07-27 |
2002-02-07 |
Mayo Foundation For Medical Education And Research |
B7-h3 and b7-h4, novel immunoregulatory molecules
|
|
US7975021B2
(en)
*
|
2000-10-23 |
2011-07-05 |
Clearplay, Inc. |
Method and user interface for downloading audio and video content filters to a media player
|
|
US6911311B2
(en)
*
|
2001-01-04 |
2005-06-28 |
Myriad Genetics, Inc. |
Method of detecting protein-protein interactions
|
|
JP2004519233A
(ja)
*
|
2001-02-19 |
2004-07-02 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング |
免疫原性の低減された修飾された抗egfr抗体
|
|
US20050215727A1
(en)
*
|
2001-05-01 |
2005-09-29 |
Corium |
Water-absorbent adhesive compositions and associated methods of manufacture and use
|
|
IL150013A
(en)
*
|
2002-06-04 |
2007-06-17 |
Gil Hecht |
Swivel cutting tool
|
|
EP1539218A4
(en)
*
|
2002-06-20 |
2007-08-22 |
Univ California |
COMPOSITIONS AND METHODS FOR MODULATING LYMPHOCYTE ACTIVITY
|
|
US20040152105A1
(en)
*
|
2002-09-06 |
2004-08-05 |
Cytos Biotechnology Ag. |
Immune modulatory compounds and methods
|
|
US7449300B2
(en)
*
|
2002-11-21 |
2008-11-11 |
Mayo Foundation For Medical Education And Research |
Detection of antibodies specific for B7-H1 in subjects with diseases or pathological conditions mediated by activated T cells
|
|
US20050163772A1
(en)
*
|
2003-06-16 |
2005-07-28 |
University Of Washington |
B7S1: an immune modulator
|
|
US7334413B2
(en)
*
|
2004-05-07 |
2008-02-26 |
Rosemount Aerospace Inc. |
Apparatus, system and method for observing combustion conditions in a gas turbine engine
|
|
DE102004060403A1
(de)
*
|
2004-12-14 |
2006-07-06 |
Trützschler GmbH & Co KG |
Vorrichtung in der Spinnereivorbereitung zur Speisung einer Mehrzahl von Füllschächten, insbesondere Mischer, mit Fasermaterial
|
|
US7694100B2
(en)
*
|
2004-12-20 |
2010-04-06 |
Intel Corporation |
Managing system memory resident device management queues
|
|
BRPI0607579A2
(pt)
*
|
2005-03-23 |
2009-09-15 |
Pfizer Prod Inc |
uso de anticorpo anti-ctla4 e indolinona para a preparação de medicamentos para o tratamento de cáncer
|
|
EP3130350A1
(en)
*
|
2005-06-08 |
2017-02-15 |
Dana-Farber Cancer Institute, Inc. |
Methods and compositions for the treatment of persistent infections and cancer by inhibiting the programmed cell death 1 (pd-1)pathway
|
|
US20070039150A1
(en)
*
|
2005-08-08 |
2007-02-22 |
Thomas David L |
Convertible furniture system comprised of modular convertible box frames and methods of forming various furniture configurations therefrom
|
|
KR100779170B1
(ko)
*
|
2005-08-16 |
2007-11-23 |
학교법인 포항공과대학교 |
광양자테 홀 발광소자의 버트 커플링 방법
|
|
JP4730263B2
(ja)
*
|
2005-09-21 |
2011-07-20 |
富士ゼロックス株式会社 |
画像処理装置の保守システム
|
|
US8241621B2
(en)
*
|
2006-12-18 |
2012-08-14 |
Medistem Laboratories |
Stem cell mediated treg activation/expansion for therapeutic immune modulation
|
|
US20090142342A1
(en)
|
2006-12-27 |
2009-06-04 |
Johns Hopkins University |
B7-h4 receptor agonist compositions and methods for treating inflammation and auto-immune diseases
|
|
US7989173B2
(en)
*
|
2006-12-27 |
2011-08-02 |
The Johns Hopkins University |
Detection and diagnosis of inflammatory disorders
|
|
CA2673659A1
(en)
|
2006-12-27 |
2008-07-10 |
The Johns Hopkins University |
Methods of detecting and diagnosing inflamatory responses and disorders by determining the level of soluble b7-h4
|
|
CN101399708B
(zh)
*
|
2007-09-28 |
2012-04-04 |
华为技术有限公司 |
一种建立网络性能模型的方法和设备
|
|
JP2011503104A
(ja)
*
|
2007-11-09 |
2011-01-27 |
カリフォルニア インスティテュート オブ テクノロジー |
免疫調節化合物ならびに関連組成物および方法
|
|
US9005616B2
(en)
*
|
2009-08-31 |
2015-04-14 |
Amplimmune, Inc. |
Methods and compositions for the inhibition of transplant rejection
|