JP2011201907A5 - - Google Patents

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Publication number
JP2011201907A5
JP2011201907A5 JP2011119894A JP2011119894A JP2011201907A5 JP 2011201907 A5 JP2011201907 A5 JP 2011201907A5 JP 2011119894 A JP2011119894 A JP 2011119894A JP 2011119894 A JP2011119894 A JP 2011119894A JP 2011201907 A5 JP2011201907 A5 JP 2011201907A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
composition according
trinol
interphenylene
methano
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011119894A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011201907A (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2011201907A publication Critical patent/JP2011201907A/ja
Publication of JP2011201907A5 publication Critical patent/JP2011201907A5/ja
Pending legal-status Critical Current

Links

JP2011119894A 1999-03-18 2011-05-30 ベンゾインデンプロスタグランジンの吸入送達法 Pending JP2011201907A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12499999P 1999-03-18 1999-03-18
US60/124,999 1999-03-18

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2000604834A Division JP4819224B2 (ja) 1999-03-18 2000-03-17 ベンゾインデンプロスタグランジンの吸入送達法

Publications (2)

Publication Number Publication Date
JP2011201907A JP2011201907A (ja) 2011-10-13
JP2011201907A5 true JP2011201907A5 (enExample) 2012-08-16

Family

ID=22417774

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2000604834A Expired - Lifetime JP4819224B2 (ja) 1999-03-18 2000-03-17 ベンゾインデンプロスタグランジンの吸入送達法
JP2011119894A Pending JP2011201907A (ja) 1999-03-18 2011-05-30 ベンゾインデンプロスタグランジンの吸入送達法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2000604834A Expired - Lifetime JP4819224B2 (ja) 1999-03-18 2000-03-17 ベンゾインデンプロスタグランジンの吸入送達法

Country Status (13)

Country Link
US (2) US6521212B1 (enExample)
EP (1) EP1161234B1 (enExample)
JP (2) JP4819224B2 (enExample)
KR (1) KR100750384B1 (enExample)
CN (1) CN1196479C (enExample)
AT (1) ATE245979T1 (enExample)
AU (1) AU4082700A (enExample)
CA (1) CA2365890C (enExample)
DE (1) DE60004181T2 (enExample)
DK (1) DK1161234T3 (enExample)
ES (1) ES2203449T3 (enExample)
PT (1) PT1161234E (enExample)
WO (1) WO2000054758A2 (enExample)

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US20080280986A1 (en) 2007-02-09 2008-11-13 United Therapeutics Corporation Treprostinil treatment for interstitial lung disease and asthma
EP2252570B1 (en) 2007-12-17 2017-04-05 United Therapeutics Corporation An improved process to prepare treprostinil, the active ingredient in remodulin ®
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CN103193627B (zh) 2012-01-10 2016-04-20 上海天伟生物制药有限公司 一种前列腺素类似物的晶型及其制备方法和用途
CN103193626B (zh) 2012-01-10 2016-05-11 上海天伟生物制药有限公司 一种前列腺素类似物的晶型及其制备方法和用途
US9387214B2 (en) 2012-01-13 2016-07-12 United Therapeutics Corporation Method of identifying therapies for pulmonary hypertension
CA2890219A1 (en) * 2012-11-30 2014-06-05 Insmed Incorporated Prostacylin compositions and methods for using the same
KR102347340B1 (ko) 2013-03-14 2022-01-06 유나이티드 세러퓨틱스 코오포레이션 트레프로스티닐의 고체 형태
US20140275616A1 (en) 2013-03-15 2014-09-18 United Therapeutics Corporation Salts of treprostinil
WO2014160638A1 (en) 2013-03-25 2014-10-02 United Therapeutics Corporation Process of making prostacyclin compounds with linker thiol and pegylated forms
CN108947843A (zh) 2013-10-25 2018-12-07 英斯梅德股份有限公司 前列环素化合物、其组合物及使用方法
ES2908142T3 (es) 2014-06-13 2022-04-27 United Therapeutics Corp Formulaciones de treprostinil
KR101890080B1 (ko) 2014-10-20 2018-09-20 유나이티드 쎄러퓨틱스 코포레이션 프로스타시클린 유도체 제조를 위한 중간체의 합성
US10343979B2 (en) 2014-11-18 2019-07-09 Insmed Incorporated Methods of manufacturing treprostinil and treprostinil derivative prodrugs
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IL310250B2 (en) 2016-05-05 2025-09-01 Liquidia Tech Inc Terpostinil in dry powder form for the treatment of pulmonary hypertension
CN110678174A (zh) 2016-09-26 2020-01-10 联合治疗学有限公司 曲前列环素的前药
CN110381951A (zh) 2016-12-14 2019-10-25 瑞必治公司 用于治疗肺性高血压和其他肺病症的方法及组合物
US10799653B2 (en) 2017-01-09 2020-10-13 United Therapeutics Corporation Aerosol delivery device and method for manufacturing and operating the same
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US10883084B2 (en) 2018-10-05 2021-01-05 Xenotherapeutics, Inc. Personalized cells, tissues, and organs for transplantation from a humanized, bespoke, designated-pathogen free, (non-human) donor and methods and products relating to same
US11458098B2 (en) 2019-04-29 2022-10-04 Insmed Incorporated Dry powder compositions of treprostinil prodrugs and methods of use thereof
EP3750528A1 (en) 2019-06-11 2020-12-16 Nexien Biopharma, Inc. Compositions for treating dystrophies and myotonia
JP2022546314A (ja) 2019-08-23 2022-11-04 ユナイテッド セラピューティクス コーポレイション トレプロスチニルプロドラッグ
US11339110B2 (en) 2019-12-19 2022-05-24 Chirogate International Inc. Efficient crystallization process for preparing ultrapure Treprostinil and crystal prepared therefrom
WO2021211916A1 (en) 2020-04-17 2021-10-21 United Therapeutics Corporation Treprostinil for use in the treatment of intersitial lung disease
CN116113415A (zh) 2020-06-09 2023-05-12 联合治疗公司 曲前列尼尔的富马酰基二酮哌啶前药
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EP4301372A1 (en) 2021-03-03 2024-01-10 United Therapeutics Corporation A dry powder composition of trestinil and its prodrug thereof and further comprising comprising (e)-3,6-bis[4-(n-carbonyl-2-propenyl)amidobutyl]-2,5-diketopiperazine (fdkp)
EP4475819A1 (en) 2022-02-08 2024-12-18 United Therapeutics Corporation Treprostinil iloprost combination therapy
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US5190972A (en) * 1992-01-27 1993-03-02 The University Of Melbourne Method of combatting cyclosporine organ toxicity with prostaglandin analogs
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