JP2014530801A5 - - Google Patents
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- Publication number
- JP2014530801A5 JP2014530801A5 JP2014517060A JP2014517060A JP2014530801A5 JP 2014530801 A5 JP2014530801 A5 JP 2014530801A5 JP 2014517060 A JP2014517060 A JP 2014517060A JP 2014517060 A JP2014517060 A JP 2014517060A JP 2014530801 A5 JP2014530801 A5 JP 2014530801A5
- Authority
- JP
- Japan
- Prior art keywords
- acid
- oral administration
- liquid
- administration according
- agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 10
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical group CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 9
- 239000007788 liquid Substances 0.000 claims 9
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims 6
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 6
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims 6
- 239000004310 lactic acid Substances 0.000 claims 5
- 235000014655 lactic acid Nutrition 0.000 claims 5
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Chemical compound OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 claims 4
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims 4
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims 4
- 239000004471 Glycine Substances 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 3
- 235000011187 glycerol Nutrition 0.000 claims 3
- 239000002904 solvent Substances 0.000 claims 3
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 claims 2
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims 2
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims 2
- 235000011054 acetic acid Nutrition 0.000 claims 2
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims 2
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims 2
- 235000015165 citric acid Nutrition 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 239000001630 malic acid Substances 0.000 claims 2
- 235000011090 malic acid Nutrition 0.000 claims 2
- 239000001384 succinic acid Substances 0.000 claims 2
- 235000011044 succinic acid Nutrition 0.000 claims 2
- 239000011975 tartaric acid Substances 0.000 claims 2
- 235000002906 tartaric acid Nutrition 0.000 claims 2
- ZKIAIYBUSXZPLP-UHFFFAOYSA-N brexpiprazole Chemical compound C1=C2NC(=O)C=CC2=CC=C1OCCCCN(CC1)CCN1C1=CC=CC2=C1C=CS2 ZKIAIYBUSXZPLP-UHFFFAOYSA-N 0.000 claims 1
- 239000000796 flavoring agent Substances 0.000 claims 1
- 235000019634 flavors Nutrition 0.000 claims 1
- 230000000873 masking effect Effects 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 claims 1
- 230000002335 preservative effect Effects 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000003381 stabilizer Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161548859P | 2011-10-19 | 2011-10-19 | |
| US61/548,859 | 2011-10-19 | ||
| PCT/JP2012/077668 WO2013058411A1 (en) | 2011-10-19 | 2012-10-19 | Solution for oral administration |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014530801A JP2014530801A (ja) | 2014-11-20 |
| JP2014530801A5 true JP2014530801A5 (enExample) | 2015-12-03 |
| JP6077534B2 JP6077534B2 (ja) | 2017-02-08 |
Family
ID=47178263
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014517060A Active JP6077534B2 (ja) | 2011-10-19 | 2012-10-19 | 経口投与用液剤 |
Country Status (35)
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JOP20200109A1 (ar) | 2012-04-23 | 2017-06-16 | Otsuka Pharma Co Ltd | مستحضر قابل للحقن |
| JP6203682B2 (ja) * | 2013-07-10 | 2017-09-27 | 共和薬品工業株式会社 | アリピプラゾール含有水性液剤 |
| UA124498C2 (uk) * | 2015-12-01 | 2021-09-29 | Общєство С Огранічєнной Отвєтствєнностью "Валєнта-Інтєллєкт" | Фармацевтична композиція для лікування інфекційно-запальних захворювань місцевого застосування і спосіб її одержання та застосування (варіанти) |
| RU2633635C1 (ru) * | 2016-06-29 | 2017-10-16 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Фармацевтическая композиция для лечения инфекционно-воспалительных заболеваний местного применения и способ ее получения и применения |
| WO2017095265A1 (ru) * | 2015-12-01 | 2017-06-08 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Фармацевтическая композиция для лечения инфекционно-воспалительных заболеваний местного применения и способ ее получения и применения |
| RU2627423C1 (ru) * | 2016-06-29 | 2017-08-08 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Фармацевтическая композиция для лечения инфекционно-воспалительных заболеваний местного применения и способ ее получения и применения |
| JP6786240B2 (ja) * | 2016-03-31 | 2020-11-18 | 小林製薬株式会社 | 粘性経口組成物 |
| WO2019075127A1 (en) * | 2017-10-10 | 2019-04-18 | Vertice Pharma, Llc | ORAL MICODRIN HYDROCHLORIDE SOLUTION AND USES THEREOF |
| WO2021029020A1 (ja) * | 2019-08-13 | 2021-02-18 | 大塚製薬株式会社 | 経口医薬組成物 |
| JP2021115288A (ja) * | 2020-01-28 | 2021-08-10 | 青葉化成株式会社 | 液状組成物および液状医療材料 |
| CA3184420A1 (en) | 2020-06-30 | 2022-01-06 | Mark C. Faulkner | Compositions and methods for treatment of vaginal infections |
| EP4171513A4 (en) * | 2020-06-30 | 2024-07-17 | VIREO Systems, Inc. | COMPOSITIONS FOR ODOUR AND ITCHING CONTROL AND METHODS AND DEVICES FOR THEIR ADMINISTRATION |
| WO2022218356A1 (zh) * | 2021-04-13 | 2022-10-20 | 上海博志研新药物技术有限公司 | 一种布瑞哌唑口溶膜组合物、其制备方法及应用 |
| CN115414322A (zh) * | 2022-07-05 | 2022-12-02 | 杭州民生药物研究院有限公司 | 一种富马酸卢帕他定口服液体制剂及其制备工艺 |
| CN116966140A (zh) * | 2023-08-18 | 2023-10-31 | 四川阿赛斯生物科技有限公司 | 一种含有布瑞哌唑的口服溶液及其制备方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1420077A (en) * | 1972-04-14 | 1976-01-07 | Unilever Ltd | Process for imparting or enhancing fresh cheese flavour in a food digital transmission systems |
| MY129350A (en) * | 2001-04-25 | 2007-03-30 | Bristol Myers Squibb Co | Aripiprazole oral solution |
| KR101027570B1 (ko) * | 2002-05-03 | 2011-04-06 | 이스라엘 인스티튜트 포 바이올로지컬 리서치 | 중추 및 말초 신경계 장애의 치료를 위한 방법 및 조성물, 및 그에 유용한 신규 화합물 |
| US20080032384A1 (en) * | 2004-04-22 | 2008-02-07 | Takehiko Nomura | Pharmaceutical Preparation Containing Bacterial Cell Wall Skeleton |
| JP4315393B2 (ja) * | 2005-04-14 | 2009-08-19 | 大塚製薬株式会社 | 複素環化合物 |
| TWI320783B (en) * | 2005-04-14 | 2010-02-21 | Otsuka Pharma Co Ltd | Heterocyclic compound |
| ES2390353T3 (es) * | 2005-06-13 | 2012-11-12 | Dainippon Sumitomo Pharma Co., Ltd. | Preparación de disolución |
| PT1948133E (pt) * | 2005-09-01 | 2011-08-01 | Baxter Healthcare Sa | Formulação de argatroban que compreende um ácido como solubilizante |
| WO2008016165A2 (en) * | 2006-07-31 | 2008-02-07 | Asubio Pharma Co., Ltd. | Liquid preparation |
| KR20100072253A (ko) * | 2007-09-17 | 2010-06-30 | 쉐링 코포레이션 | 사이클린-의존성 키나제 억제 화합물을 함유하는 제형 및 이를 사용한 종양의 치료방법 |
| JP2010540448A (ja) * | 2007-09-21 | 2010-12-24 | フォレスト・ラボラトリーズ・ホールディングス・リミテッド | 非経口投与に適したセフェム誘導体を含む可溶製剤 |
| US8263652B2 (en) * | 2007-10-31 | 2012-09-11 | Sk Biopharmaceuticals Co., Ltd. | Stabilized pediatric suspension of carisbamate |
| RU2535089C2 (ru) * | 2010-08-24 | 2014-12-10 | Оцука Фармасьютикал Ко., Лтд. | Суспензия и затвердевшая композиция, содержащие производное карбостирила и силиконовое масло и/или производное силиконового масла |
| CN102119922A (zh) * | 2011-03-03 | 2011-07-13 | 天津市炜杰科技有限公司 | 以酸作为增溶剂的21(s)阿加曲班静脉注射液 |
| JOP20120083B1 (ar) * | 2011-04-05 | 2021-08-17 | Otsuka Pharma Co Ltd | توليفات تشتمل على بريكس ببرازول أو ملح منه وعقار ثاني للاستخدام في علاج اضطراب cns |
-
2012
- 2012-10-18 TW TW106124366A patent/TWI679977B/zh active
- 2012-10-18 TW TW101138422A patent/TWI632921B/zh active
- 2012-10-18 JO JOP/2012/0316A patent/JO3190B1/ar active
- 2012-10-18 AR ARP120103877A patent/AR088372A1/es not_active Application Discontinuation
- 2012-10-19 PT PT127847531T patent/PT2768508T/pt unknown
- 2012-10-19 SI SI201230656A patent/SI2768508T1/sl unknown
- 2012-10-19 WO PCT/JP2012/077668 patent/WO2013058411A1/en not_active Ceased
- 2012-10-19 BR BR112014009330A patent/BR112014009330A2/pt not_active Application Discontinuation
- 2012-10-19 US US14/352,479 patent/US20140303183A1/en not_active Abandoned
- 2012-10-19 PH PH1/2014/500816A patent/PH12014500816A1/en unknown
- 2012-10-19 CA CA2851999A patent/CA2851999C/en active Active
- 2012-10-19 DK DK12784753.1T patent/DK2768508T3/en active
- 2012-10-19 CN CN201711285346.0A patent/CN107823131A/zh active Pending
- 2012-10-19 ME MEP-2016-143A patent/ME02459B/me unknown
- 2012-10-19 LT LTEP12784753.1T patent/LT2768508T/lt unknown
- 2012-10-19 EA EA202190445A patent/EA202190445A2/ru unknown
- 2012-10-19 EA EA201490812A patent/EA201490812A1/ru unknown
- 2012-10-19 EP EP12784753.1A patent/EP2768508B1/en active Active
- 2012-10-19 HR HRP20160989TT patent/HRP20160989T1/hr unknown
- 2012-10-19 MX MX2014004529A patent/MX347309B/es active IP Right Grant
- 2012-10-19 CN CN201280051524.2A patent/CN103889426A/zh active Pending
- 2012-10-19 SG SG11201401273SA patent/SG11201401273SA/en unknown
- 2012-10-19 UA UAA201405162A patent/UA111506C2/uk unknown
- 2012-10-19 HU HUE12784753A patent/HUE028869T2/en unknown
- 2012-10-19 ES ES12784753.1T patent/ES2583137T3/es active Active
- 2012-10-19 MY MYPI2014700955A patent/MY169096A/en unknown
- 2012-10-19 KR KR1020147013277A patent/KR101856283B1/ko active Active
- 2012-10-19 JP JP2014517060A patent/JP6077534B2/ja active Active
- 2012-10-19 RS RS20160549A patent/RS54967B1/sr unknown
- 2012-10-19 AU AU2012326978A patent/AU2012326978B2/en active Active
- 2012-10-19 PL PL12784753.1T patent/PL2768508T3/pl unknown
-
2014
- 2014-04-07 IL IL231988A patent/IL231988A/en active IP Right Grant
- 2014-04-11 ZA ZA2014/02669A patent/ZA201402669B/en unknown
- 2014-04-15 IN IN2987DEN2014 patent/IN2014DN02987A/en unknown
- 2014-04-15 CL CL2014000967A patent/CL2014000967A1/es unknown
- 2014-05-13 CO CO14102721A patent/CO6950486A2/es unknown
-
2016
- 2016-01-21 US US15/003,347 patent/US20160213665A1/en not_active Abandoned
- 2016-07-18 CY CY20161100695T patent/CY1117794T1/el unknown
- 2016-09-29 SM SM201600341T patent/SMT201600341B/it unknown
-
2017
- 2017-02-24 US US15/441,881 patent/US20170182036A1/en not_active Abandoned
- 2017-08-11 AU AU2017213570A patent/AU2017213570A1/en not_active Abandoned
-
2018
- 2018-05-25 US US15/989,294 patent/US20180271858A1/en not_active Abandoned
-
2019
- 2019-09-10 US US16/566,178 patent/US20200171023A1/en not_active Abandoned
-
2020
- 2020-11-13 US US17/097,168 patent/US20210236483A1/en not_active Abandoned
-
2023
- 2023-03-27 US US18/190,839 patent/US20240009186A1/en not_active Abandoned
-
2024
- 2024-08-01 US US18/791,730 patent/US20250099460A1/en active Pending
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