CL2014000967A1 - Solucion para administracion oral que comprende 7-[4-(4-benzo [b] tiofen-4-il-piperazin-1-il)butoxi]-1h-quinolin-2-ona y al menos un compuesto seleccionado de los acidos lactico, fosforico, glicolico, malico, tartarico, citrico, succinico y acetico. - Google Patents
Solucion para administracion oral que comprende 7-[4-(4-benzo [b] tiofen-4-il-piperazin-1-il)butoxi]-1h-quinolin-2-ona y al menos un compuesto seleccionado de los acidos lactico, fosforico, glicolico, malico, tartarico, citrico, succinico y acetico.Info
- Publication number
- CL2014000967A1 CL2014000967A1 CL2014000967A CL2014000967A CL2014000967A1 CL 2014000967 A1 CL2014000967 A1 CL 2014000967A1 CL 2014000967 A CL2014000967 A CL 2014000967A CL 2014000967 A CL2014000967 A CL 2014000967A CL 2014000967 A1 CL2014000967 A1 CL 2014000967A1
- Authority
- CL
- Chile
- Prior art keywords
- malico
- quinolin
- thiophen
- piperazin
- glycolic
- Prior art date
Links
- ZKIAIYBUSXZPLP-UHFFFAOYSA-N brexpiprazole Chemical compound C1=C2NC(=O)C=CC2=CC=C1OCCCCN(CC1)CCN1C1=CC=CC2=C1C=CS2 ZKIAIYBUSXZPLP-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical class CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 title 1
- 235000014655 lactic acid Nutrition 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- A—HUMAN NECESSITIES
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
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- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
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- A—HUMAN NECESSITIES
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/08—Solutions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Psychiatry (AREA)
- Inorganic Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161548859P | 2011-10-19 | 2011-10-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2014000967A1 true CL2014000967A1 (es) | 2014-10-03 |
Family
ID=47178263
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2014000967A CL2014000967A1 (es) | 2011-10-19 | 2014-04-15 | Solucion para administracion oral que comprende 7-[4-(4-benzo [b] tiofen-4-il-piperazin-1-il)butoxi]-1h-quinolin-2-ona y al menos un compuesto seleccionado de los acidos lactico, fosforico, glicolico, malico, tartarico, citrico, succinico y acetico. |
Country Status (35)
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JOP20200109A1 (ar) | 2012-04-23 | 2017-06-16 | Otsuka Pharma Co Ltd | مستحضر قابل للحقن |
| JP6203682B2 (ja) * | 2013-07-10 | 2017-09-27 | 共和薬品工業株式会社 | アリピプラゾール含有水性液剤 |
| UA124498C2 (uk) * | 2015-12-01 | 2021-09-29 | Общєство С Огранічєнной Отвєтствєнностью "Валєнта-Інтєллєкт" | Фармацевтична композиція для лікування інфекційно-запальних захворювань місцевого застосування і спосіб її одержання та застосування (варіанти) |
| WO2017095265A1 (ru) * | 2015-12-01 | 2017-06-08 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Фармацевтическая композиция для лечения инфекционно-воспалительных заболеваний местного применения и способ ее получения и применения |
| RU2633635C1 (ru) * | 2016-06-29 | 2017-10-16 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Фармацевтическая композиция для лечения инфекционно-воспалительных заболеваний местного применения и способ ее получения и применения |
| RU2627423C1 (ru) * | 2016-06-29 | 2017-08-08 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Фармацевтическая композиция для лечения инфекционно-воспалительных заболеваний местного применения и способ ее получения и применения |
| JP6786240B2 (ja) * | 2016-03-31 | 2020-11-18 | 小林製薬株式会社 | 粘性経口組成物 |
| EP3582765B1 (en) * | 2017-10-10 | 2021-04-28 | Vertice Pharma, LLC | Midodrine hydrochloride oral solution and uses thereof |
| WO2021029020A1 (ja) * | 2019-08-13 | 2021-02-18 | 大塚製薬株式会社 | 経口医薬組成物 |
| JP2021115288A (ja) * | 2020-01-28 | 2021-08-10 | 青葉化成株式会社 | 液状組成物および液状医療材料 |
| US12109195B2 (en) | 2020-06-30 | 2024-10-08 | Vireo Systems, Inc. | Compositions and methods for treatment of vaginal infections |
| EP4171513A4 (en) * | 2020-06-30 | 2024-07-17 | VIREO Systems, Inc. | COMPOSITIONS FOR ODOUR AND ITCHING CONTROL AND METHODS AND DEVICES FOR THEIR ADMINISTRATION |
| TWI820673B (zh) * | 2021-04-13 | 2023-11-01 | 大陸商上海雲晟研新生物科技有限公司 | 布瑞哌唑口溶膜組合物、其製備方法及用途 |
| CN115414322A (zh) * | 2022-07-05 | 2022-12-02 | 杭州民生药物研究院有限公司 | 一种富马酸卢帕他定口服液体制剂及其制备工艺 |
| CN116966140A (zh) * | 2023-08-18 | 2023-10-31 | 四川阿赛斯生物科技有限公司 | 一种含有布瑞哌唑的口服溶液及其制备方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| GB1420077A (en) * | 1972-04-14 | 1976-01-07 | Unilever Ltd | Process for imparting or enhancing fresh cheese flavour in a food digital transmission systems |
| MY129350A (en) * | 2001-04-25 | 2007-03-30 | Bristol Myers Squibb Co | Aripiprazole oral solution |
| KR101027570B1 (ko) * | 2002-05-03 | 2011-04-06 | 이스라엘 인스티튜트 포 바이올로지컬 리서치 | 중추 및 말초 신경계 장애의 치료를 위한 방법 및 조성물, 및 그에 유용한 신규 화합물 |
| US20080032384A1 (en) * | 2004-04-22 | 2008-02-07 | Takehiko Nomura | Pharmaceutical Preparation Containing Bacterial Cell Wall Skeleton |
| TWI320783B (en) * | 2005-04-14 | 2010-02-21 | Otsuka Pharma Co Ltd | Heterocyclic compound |
| JP4315393B2 (ja) | 2005-04-14 | 2009-08-19 | 大塚製薬株式会社 | 複素環化合物 |
| KR101328857B1 (ko) * | 2005-06-13 | 2013-11-13 | 다이닛본 스미토모 세이야꾸 가부시끼가이샤 | 가용화 제제 |
| ATE514416T1 (de) * | 2005-09-01 | 2011-07-15 | Baxter Internat Inc A Delaware Corp | Argatrobanformulierung mit einer säure als lösungsvermittler |
| US20100004267A1 (en) * | 2006-07-31 | 2010-01-07 | Asubio Pharma Co., Ltd. | Liquid preparation |
| JP2010539173A (ja) * | 2007-09-17 | 2010-12-16 | シェーリング コーポレイション | サイクリン依存キナーゼ阻害化合物を含む製剤およびこの製剤を用いて腫瘍を処置する方法 |
| US20090082326A1 (en) * | 2007-09-21 | 2009-03-26 | Forest Laboratories Holdings Limited | Soluble dosage forms containing cephem derivatives suitable for parenteral administration |
| US8263652B2 (en) * | 2007-10-31 | 2012-09-11 | Sk Biopharmaceuticals Co., Ltd. | Stabilized pediatric suspension of carisbamate |
| NZ603076A (en) * | 2010-08-24 | 2014-12-24 | Otsuka Pharma Co Ltd | Suspension and cake composition containing carbostyril derivative and silicone oil and/or silicone oil derivative |
| CN102119922A (zh) * | 2011-03-03 | 2011-07-13 | 天津市炜杰科技有限公司 | 以酸作为增溶剂的21(s)阿加曲班静脉注射液 |
| JOP20120083B1 (ar) * | 2011-04-05 | 2021-08-17 | Otsuka Pharma Co Ltd | توليفات تشتمل على بريكس ببرازول أو ملح منه وعقار ثاني للاستخدام في علاج اضطراب cns |
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2012
- 2012-10-18 TW TW106124366A patent/TWI679977B/zh active
- 2012-10-18 TW TW101138422A patent/TWI632921B/zh active
- 2012-10-18 AR ARP120103877A patent/AR088372A1/es not_active Application Discontinuation
- 2012-10-18 JO JOP/2012/0316A patent/JO3190B1/ar active
- 2012-10-19 WO PCT/JP2012/077668 patent/WO2013058411A1/en not_active Ceased
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- 2012-10-19 PH PH1/2014/500816A patent/PH12014500816A1/en unknown
- 2012-10-19 EP EP12784753.1A patent/EP2768508B1/en active Active
- 2012-10-19 JP JP2014517060A patent/JP6077534B2/ja active Active
- 2012-10-19 HU HUE12784753A patent/HUE028869T2/en unknown
- 2012-10-19 RS RS20160549A patent/RS54967B1/sr unknown
- 2012-10-19 DK DK12784753.1T patent/DK2768508T3/en active
- 2012-10-19 CA CA2851999A patent/CA2851999C/en active Active
- 2012-10-19 US US14/352,479 patent/US20140303183A1/en not_active Abandoned
- 2012-10-19 BR BR112014009330A patent/BR112014009330A2/pt not_active Application Discontinuation
- 2012-10-19 PL PL12784753.1T patent/PL2768508T3/pl unknown
- 2012-10-19 MX MX2014004529A patent/MX347309B/es active IP Right Grant
- 2012-10-19 CN CN201711285346.0A patent/CN107823131A/zh active Pending
- 2012-10-19 ME MEP-2016-143A patent/ME02459B/me unknown
- 2012-10-19 KR KR1020147013277A patent/KR101856283B1/ko active Active
- 2012-10-19 SI SI201230656A patent/SI2768508T1/sl unknown
- 2012-10-19 UA UAA201405162A patent/UA111506C2/uk unknown
- 2012-10-19 PT PT127847531T patent/PT2768508T/pt unknown
- 2012-10-19 HR HRP20160989TT patent/HRP20160989T1/hr unknown
- 2012-10-19 MY MYPI2014700955A patent/MY169096A/en unknown
- 2012-10-19 EA EA201490812A patent/EA201490812A1/ru unknown
- 2012-10-19 SG SG11201401273SA patent/SG11201401273SA/en unknown
- 2012-10-19 LT LTEP12784753.1T patent/LT2768508T/lt unknown
- 2012-10-19 EA EA202190445A patent/EA202190445A2/ru unknown
- 2012-10-19 CN CN201280051524.2A patent/CN103889426A/zh active Pending
- 2012-10-19 ES ES12784753.1T patent/ES2583137T3/es active Active
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2014
- 2014-04-07 IL IL231988A patent/IL231988A/en active IP Right Grant
- 2014-04-11 ZA ZA2014/02669A patent/ZA201402669B/en unknown
- 2014-04-15 CL CL2014000967A patent/CL2014000967A1/es unknown
- 2014-04-15 IN IN2987DEN2014 patent/IN2014DN02987A/en unknown
- 2014-05-13 CO CO14102721A patent/CO6950486A2/es unknown
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2016
- 2016-01-21 US US15/003,347 patent/US20160213665A1/en not_active Abandoned
- 2016-07-18 CY CY20161100695T patent/CY1117794T1/el unknown
- 2016-09-29 SM SM201600341T patent/SMT201600341B/it unknown
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2017
- 2017-02-24 US US15/441,881 patent/US20170182036A1/en not_active Abandoned
- 2017-08-11 AU AU2017213570A patent/AU2017213570A1/en not_active Abandoned
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2018
- 2018-05-25 US US15/989,294 patent/US20180271858A1/en not_active Abandoned
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2019
- 2019-09-10 US US16/566,178 patent/US20200171023A1/en not_active Abandoned
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2020
- 2020-11-13 US US17/097,168 patent/US20210236483A1/en not_active Abandoned
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2023
- 2023-03-27 US US18/190,839 patent/US20240009186A1/en not_active Abandoned
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2024
- 2024-08-01 US US18/791,730 patent/US20250099460A1/en active Pending
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