CL2014000967A1 - Solucion para administracion oral que comprende 7-[4-(4-benzo [b] tiofen-4-il-piperazin-1-il)butoxi]-1h-quinolin-2-ona y al menos un compuesto seleccionado de los acidos lactico, fosforico, glicolico, malico, tartarico, citrico, succinico y acetico. - Google Patents

Solucion para administracion oral que comprende 7-[4-(4-benzo [b] tiofen-4-il-piperazin-1-il)butoxi]-1h-quinolin-2-ona y al menos un compuesto seleccionado de los acidos lactico, fosforico, glicolico, malico, tartarico, citrico, succinico y acetico.

Info

Publication number
CL2014000967A1
CL2014000967A1 CL2014000967A CL2014000967A CL2014000967A1 CL 2014000967 A1 CL2014000967 A1 CL 2014000967A1 CL 2014000967 A CL2014000967 A CL 2014000967A CL 2014000967 A CL2014000967 A CL 2014000967A CL 2014000967 A1 CL2014000967 A1 CL 2014000967A1
Authority
CL
Chile
Prior art keywords
malico
quinolin
thiophen
piperazin
glycolic
Prior art date
Application number
CL2014000967A
Other languages
English (en)
Spanish (es)
Inventor
Ayako Okamoto
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of CL2014000967A1 publication Critical patent/CL2014000967A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/191Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/194Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/661Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Psychiatry (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CL2014000967A 2011-10-19 2014-04-15 Solucion para administracion oral que comprende 7-[4-(4-benzo [b] tiofen-4-il-piperazin-1-il)butoxi]-1h-quinolin-2-ona y al menos un compuesto seleccionado de los acidos lactico, fosforico, glicolico, malico, tartarico, citrico, succinico y acetico. CL2014000967A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161548859P 2011-10-19 2011-10-19

Publications (1)

Publication Number Publication Date
CL2014000967A1 true CL2014000967A1 (es) 2014-10-03

Family

ID=47178263

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2014000967A CL2014000967A1 (es) 2011-10-19 2014-04-15 Solucion para administracion oral que comprende 7-[4-(4-benzo [b] tiofen-4-il-piperazin-1-il)butoxi]-1h-quinolin-2-ona y al menos un compuesto seleccionado de los acidos lactico, fosforico, glicolico, malico, tartarico, citrico, succinico y acetico.

Country Status (35)

Country Link
US (8) US20140303183A1 (enExample)
EP (1) EP2768508B1 (enExample)
JP (1) JP6077534B2 (enExample)
KR (1) KR101856283B1 (enExample)
CN (2) CN103889426A (enExample)
AR (1) AR088372A1 (enExample)
AU (2) AU2012326978B2 (enExample)
BR (1) BR112014009330A2 (enExample)
CA (1) CA2851999C (enExample)
CL (1) CL2014000967A1 (enExample)
CO (1) CO6950486A2 (enExample)
CY (1) CY1117794T1 (enExample)
DK (1) DK2768508T3 (enExample)
EA (2) EA201490812A1 (enExample)
ES (1) ES2583137T3 (enExample)
HR (1) HRP20160989T1 (enExample)
HU (1) HUE028869T2 (enExample)
IL (1) IL231988A (enExample)
IN (1) IN2014DN02987A (enExample)
JO (1) JO3190B1 (enExample)
LT (1) LT2768508T (enExample)
ME (1) ME02459B (enExample)
MX (1) MX347309B (enExample)
MY (1) MY169096A (enExample)
PH (1) PH12014500816A1 (enExample)
PL (1) PL2768508T3 (enExample)
PT (1) PT2768508T (enExample)
RS (1) RS54967B1 (enExample)
SG (1) SG11201401273SA (enExample)
SI (1) SI2768508T1 (enExample)
SM (1) SMT201600341B (enExample)
TW (2) TWI632921B (enExample)
UA (1) UA111506C2 (enExample)
WO (1) WO2013058411A1 (enExample)
ZA (1) ZA201402669B (enExample)

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RU2633635C1 (ru) * 2016-06-29 2017-10-16 Общество С Ограниченной Ответственностью "Валента-Интеллект" Фармацевтическая композиция для лечения инфекционно-воспалительных заболеваний местного применения и способ ее получения и применения
WO2017095265A1 (ru) * 2015-12-01 2017-06-08 Общество С Ограниченной Ответственностью "Валента-Интеллект" Фармацевтическая композиция для лечения инфекционно-воспалительных заболеваний местного применения и способ ее получения и применения
WO2017095266A1 (ru) * 2015-12-01 2017-06-08 Общество С Ограниченной Ответственностью "Валента-Интеллект" Фармацевтическая композиция для лечения инфекционно-воспалительных заболеваний местного применения и способ ее получения и применения (варианты)
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TWI632921B (zh) 2018-08-21
IN2014DN02987A (enExample) 2015-05-08
US20210236483A1 (en) 2021-08-05
LT2768508T (lt) 2016-09-12
ME02459B (me) 2017-02-20
CN107823131A (zh) 2018-03-23
JP2014530801A (ja) 2014-11-20
EA202190445A2 (ru) 2021-08-31
RS54967B1 (sr) 2016-11-30
JP6077534B2 (ja) 2017-02-08
EA201490812A1 (ru) 2014-09-30
JO3190B1 (ar) 2018-03-08
MX347309B (es) 2017-04-21
BR112014009330A2 (pt) 2017-04-11
UA111506C2 (uk) 2016-05-10
ZA201402669B (en) 2015-09-30
CY1117794T1 (el) 2017-05-17
CN103889426A (zh) 2014-06-25
HUE028869T2 (en) 2017-01-30
CA2851999C (en) 2020-01-07
KR20140083032A (ko) 2014-07-03
DK2768508T3 (en) 2016-08-29
TW201330873A (zh) 2013-08-01
IL231988A0 (en) 2014-05-28
US20160213665A1 (en) 2016-07-28
CO6950486A2 (es) 2014-05-20
EP2768508A1 (en) 2014-08-27
KR101856283B1 (ko) 2018-05-09
SI2768508T1 (sl) 2016-09-30
AU2012326978A1 (en) 2014-05-22
WO2013058411A1 (en) 2013-04-25
HRP20160989T1 (hr) 2016-10-07
ES2583137T3 (es) 2016-09-19
US20180271858A1 (en) 2018-09-27
IL231988A (en) 2017-09-28
US20170182036A1 (en) 2017-06-29
PT2768508T (pt) 2016-08-17
US20200171023A1 (en) 2020-06-04
MX2014004529A (es) 2014-08-01
SG11201401273SA (en) 2014-05-29
TW201737916A (zh) 2017-11-01
NZ623523A (en) 2015-12-24
CA2851999A1 (en) 2013-04-25
AR088372A1 (es) 2014-05-28
AU2017213570A1 (en) 2017-08-31
EP2768508B1 (en) 2016-07-06
SMT201600341B (it) 2016-11-10
HK1196773A1 (zh) 2014-12-24
TWI679977B (zh) 2019-12-21
US20240009186A1 (en) 2024-01-11
US20250099460A1 (en) 2025-03-27
US20140303183A1 (en) 2014-10-09
PL2768508T3 (pl) 2016-12-30
AU2012326978B2 (en) 2017-08-31
PH12014500816A1 (en) 2014-05-19
MY169096A (en) 2019-02-18

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