JP2011088927A5 - - Google Patents
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- Publication number
- JP2011088927A5 JP2011088927A5 JP2011000082A JP2011000082A JP2011088927A5 JP 2011088927 A5 JP2011088927 A5 JP 2011088927A5 JP 2011000082 A JP2011000082 A JP 2011000082A JP 2011000082 A JP2011000082 A JP 2011000082A JP 2011088927 A5 JP2011088927 A5 JP 2011088927A5
- Authority
- JP
- Japan
- Prior art keywords
- composition according
- enamel matrix
- matrix protein
- aqueous solution
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000004169 proteins and genes Human genes 0.000 claims description 11
- 108090000623 proteins and genes Proteins 0.000 claims description 11
- 102100040409 Ameloblastin Human genes 0.000 claims description 10
- 101000891247 Homo sapiens Ameloblastin Proteins 0.000 claims description 9
- 108010007570 Amelogenin Proteins 0.000 claims description 6
- 102000007325 Amelogenin Human genes 0.000 claims description 6
- HDSBZMRLPLPFLQ-UHFFFAOYSA-N Propylene glycol alginate Chemical group OC1C(O)C(OC)OC(C(O)=O)C1OC1C(O)C(O)C(C)C(C(=O)OCC(C)O)O1 HDSBZMRLPLPFLQ-UHFFFAOYSA-N 0.000 claims description 3
- 235000010409 propane-1,2-diol alginate Nutrition 0.000 claims description 3
- 239000000770 propane-1,2-diol alginate Substances 0.000 claims description 3
- 150000003839 salts Chemical class 0.000 claims description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims 14
- 239000007864 aqueous solution Substances 0.000 claims 5
- 241000124008 Mammalia Species 0.000 claims 3
- 238000000605 extraction Methods 0.000 claims 3
- 230000004968 inflammatory condition Effects 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 239000000546 pharmaceutical excipient Substances 0.000 claims 3
- 239000002253 acid Substances 0.000 claims 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical group CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 1
- 101710081264 Ameloblastin Proteins 0.000 claims 1
- 239000003513 alkali Substances 0.000 claims 1
- -1 ameline Proteins 0.000 claims 1
- 210000000988 bone and bone Anatomy 0.000 claims 1
- 229920002674 hyaluronan Polymers 0.000 claims 1
- 229960003160 hyaluronic acid Drugs 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 210000000214 mouth Anatomy 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 239000011877 solvent mixture Substances 0.000 claims 1
- 108010022248 tuftelin Proteins 0.000 claims 1
- 102000012344 tuftelin Human genes 0.000 claims 1
- 210000003298 dental enamel Anatomy 0.000 description 4
- 239000011159 matrix material Substances 0.000 description 4
- 102000004196 processed proteins & peptides Human genes 0.000 description 3
- 108090000765 processed proteins & peptides Proteins 0.000 description 3
- 102000004506 Blood Proteins Human genes 0.000 description 1
- 108010017384 Blood Proteins Proteins 0.000 description 1
- 108060003393 Granulin Proteins 0.000 description 1
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 description 1
- 108091005804 Peptidases Proteins 0.000 description 1
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 description 1
- 239000004365 Protease Substances 0.000 description 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 1
- 102000001848 Salivary Proteins and Peptides Human genes 0.000 description 1
- 108010029987 Salivary Proteins and Peptides Proteins 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 108010074702 enamel matrix proteins Proteins 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000004962 physiological condition Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK27098 | 1998-02-27 | ||
| DK0270/98 | 1998-02-27 | ||
| US8155198P | 1998-04-13 | 1998-04-13 | |
| US60/081,551 | 1998-04-13 | ||
| DKPA199801328 | 1998-10-16 | ||
| DKPA199801328 | 1998-10-16 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007131100A Division JP5024866B2 (ja) | 1998-02-27 | 2007-05-17 | 創傷治癒のためのマトリックスタンパク質組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011088927A JP2011088927A (ja) | 2011-05-06 |
| JP2011088927A5 true JP2011088927A5 (enExample) | 2012-03-22 |
| JP5227428B2 JP5227428B2 (ja) | 2013-07-03 |
Family
ID=27220558
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007131100A Expired - Lifetime JP5024866B2 (ja) | 1998-02-27 | 2007-05-17 | 創傷治癒のためのマトリックスタンパク質組成物 |
| JP2011000082A Expired - Lifetime JP5227428B2 (ja) | 1998-02-27 | 2011-01-04 | 創傷治癒のためのマトリックスタンパク質組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007131100A Expired - Lifetime JP5024866B2 (ja) | 1998-02-27 | 2007-05-17 | 創傷治癒のためのマトリックスタンパク質組成物 |
Country Status (18)
| Country | Link |
|---|---|
| EP (2) | EP1153610B1 (enExample) |
| JP (2) | JP5024866B2 (enExample) |
| KR (1) | KR20010041408A (enExample) |
| CN (1) | CN1248734C (enExample) |
| AT (2) | ATE220918T1 (enExample) |
| AU (1) | AU740468B2 (enExample) |
| BR (1) | BR9908182A (enExample) |
| CA (2) | CA2322215C (enExample) |
| DE (2) | DE69902234T2 (enExample) |
| DK (2) | DK1059934T3 (enExample) |
| ES (2) | ES2204804T3 (enExample) |
| HU (1) | HUP0101710A2 (enExample) |
| IL (1) | IL137869A0 (enExample) |
| IS (1) | IS5591A (enExample) |
| NO (1) | NO20004282L (enExample) |
| PL (1) | PL202536B1 (enExample) |
| SK (1) | SK12362000A3 (enExample) |
| WO (1) | WO1999043344A2 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030096740A1 (en) | 1999-03-10 | 2003-05-22 | Lars Hammarstrom | Matrix protein compositions for induction of apoptosis |
| US7304030B2 (en) | 2000-06-20 | 2007-12-04 | Biora Ab | Matrix protein composition for dentin regeneration |
| DE60140191D1 (de) * | 2000-06-20 | 2009-11-26 | Straumann Inst Ag | Zusammensetzungen mit matrixproteinen zur regeneration von dentin |
| US7033611B2 (en) | 2001-02-23 | 2006-04-25 | Biora Bioex Ab | Matrix protein compositions for guided connective tissue growth |
| EP1361905B8 (en) * | 2001-02-23 | 2007-12-12 | Institut Straumann Ag | Matrix protein compositions for guided connective tissue growth |
| KR100934411B1 (ko) | 2001-09-14 | 2009-12-29 | 바이오라 바이오엑스 에이비 | 면역반응을 조절하기 위한 에나멜 기질 단백질 조성물 |
| MXPA04002348A (es) * | 2001-09-14 | 2004-09-28 | Biora Bioex Ab | Composiciones de proteina de matriz de esmalte para modular respuesta inmune. |
| KR100450146B1 (ko) * | 2002-02-19 | 2004-09-30 | 정필훈 | 발치된 치아로부터 치아 단백질의 추출방법과 그의이용방법 |
| KR101123113B1 (ko) * | 2002-07-29 | 2012-03-15 | 쎄라피콘 에스.알.엘. | 코 펩티드 약학 제형 |
| JP2004307454A (ja) * | 2003-02-21 | 2004-11-04 | Seikagaku Kogyo Co Ltd | 生理活性ペプチド及びこれを含有する薬剤 |
| JP5069125B2 (ja) | 2004-12-10 | 2012-11-07 | シュトラウマン・ホールディング・アクチェンゲゼルシャフト | 新規なタンパク質配合物 |
| SE0403014D0 (sv) | 2004-12-10 | 2004-12-10 | Straumann Holding Ag | New protein formulation |
| EP1862170B1 (en) * | 2004-12-10 | 2012-03-14 | Straumann Holding AG | Enamel formulation with amelogenin |
| HUE042678T2 (hu) | 2005-08-31 | 2019-07-29 | Abraxis Bioscience Llc | Vízben rosszul oldódó gyógyszerhatóanyagok és antimikrobiális szerek |
| WO2010107794A2 (en) | 2009-03-16 | 2010-09-23 | University Of Memphis Research Foundation | Compositions and methods for delivering an agent to a wound |
| EP2496273B1 (en) | 2009-11-02 | 2016-11-30 | Straumann Holding AG | Purified emd protein composition |
| WO2011073447A1 (en) | 2009-12-18 | 2011-06-23 | Straumann Holding Ag | Emd c-depleted |
| GB0922438D0 (en) | 2009-12-22 | 2010-02-03 | Ucl Business Plc | Agents having tissue generative activity |
| CN103153334B (zh) | 2010-10-15 | 2016-11-16 | 斯特劳曼控股公司 | 包含pga的新的emd制剂 |
| US20120294898A1 (en) * | 2011-05-19 | 2012-11-22 | Warsaw Orthopedic, Inc. | Injectable dbm for soft tissue repair |
| EP2687224A1 (en) * | 2012-07-19 | 2014-01-22 | Tissue Med Biosciences Forschungs- und Entwicklungsgesellschaft mbH | Medicament for wound treatment |
| SE536581C2 (sv) | 2012-07-24 | 2014-03-11 | Rls Global Ab | Ett kit för behandling av sår eller liknande och ett preparat och metoder därav |
| CN112915281B (zh) * | 2021-03-12 | 2022-12-16 | 臻叶生物科技有限公司 | 一种无抗凝剂的prp生物膜制备装置及方法 |
| CN117138105B (zh) * | 2023-09-26 | 2025-11-11 | 邯郸惠科新材料科技有限公司 | 一种液体创口贴及其制备方法 |
| EP4656213A1 (en) * | 2024-05-27 | 2025-12-03 | Institut Straumann AG | Injectable compositions of emd fraction b |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE454480B (sv) * | 1986-09-25 | 1988-05-09 | Lars Hammarstrom | Bindningsinducerande komposition |
| SE461313B (sv) * | 1988-03-17 | 1990-02-05 | Biora Ab | Bindningsinducerande komposition |
| JPH11510377A (ja) * | 1995-07-13 | 1999-09-14 | バイオラ エイビー | エナメル質マトリックス関連ポリペプチド |
| BRPI9908182C1 (pt) * | 1998-02-27 | 2021-05-25 | Biora Ab | composições de proteína de matriz para cura de feridas |
-
1999
- 1999-02-26 DK DK99903852T patent/DK1059934T3/da active
- 1999-02-26 EP EP01201915A patent/EP1153610B1/en not_active Expired - Lifetime
- 1999-02-26 DE DE69902234T patent/DE69902234T2/de not_active Expired - Lifetime
- 1999-02-26 ES ES01201915T patent/ES2204804T3/es not_active Expired - Lifetime
- 1999-02-26 SK SK1236-2000A patent/SK12362000A3/sk unknown
- 1999-02-26 CN CNB998052205A patent/CN1248734C/zh not_active Expired - Lifetime
- 1999-02-26 AT AT99903852T patent/ATE220918T1/de not_active IP Right Cessation
- 1999-02-26 BR BR9908182-2A patent/BR9908182A/pt not_active IP Right Cessation
- 1999-02-26 PL PL343375A patent/PL202536B1/pl unknown
- 1999-02-26 AT AT01201915T patent/ATE247483T1/de not_active IP Right Cessation
- 1999-02-26 ES ES99903852T patent/ES2183510T3/es not_active Expired - Lifetime
- 1999-02-26 AU AU24368/99A patent/AU740468B2/en not_active Expired
- 1999-02-26 HU HU0101710A patent/HUP0101710A2/hu unknown
- 1999-02-26 CA CA2322215A patent/CA2322215C/en not_active Expired - Lifetime
- 1999-02-26 KR KR1020007009541A patent/KR20010041408A/ko not_active Withdrawn
- 1999-02-26 CA CA2640994A patent/CA2640994C/en not_active Expired - Lifetime
- 1999-02-26 DK DK01201915T patent/DK1153610T3/da active
- 1999-02-26 EP EP99903852A patent/EP1059934B1/en not_active Expired - Lifetime
- 1999-02-26 IL IL13786999A patent/IL137869A0/xx unknown
- 1999-02-26 DE DE69910622T patent/DE69910622T2/de not_active Expired - Lifetime
- 1999-02-26 WO PCT/IB1999/000337 patent/WO1999043344A2/en not_active Ceased
-
2000
- 2000-08-18 IS IS5591A patent/IS5591A/is unknown
- 2000-08-25 NO NO20004282A patent/NO20004282L/no not_active Application Discontinuation
-
2007
- 2007-05-17 JP JP2007131100A patent/JP5024866B2/ja not_active Expired - Lifetime
-
2011
- 2011-01-04 JP JP2011000082A patent/JP5227428B2/ja not_active Expired - Lifetime
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