|
JP2010513384A
(ja)
|
2006-12-22 |
2010-04-30 |
エフ.ホフマン−ラ ロシュ アーゲー |
スピロ−ピペリジン誘導体
|
|
AU2016200866B2
(en)
*
|
2007-03-12 |
2017-06-22 |
Glaxosmithkline Llc |
Phenyl amino pyrimidine compounds and uses thereof
|
|
PL2152701T3
(pl)
*
|
2007-03-12 |
2016-10-31 |
|
Związki fenyloaminopirymidyny i ich zastosowania
|
|
AU2013201306B2
(en)
*
|
2007-03-12 |
2015-11-12 |
Glaxosmithkline Llc |
Phenyl Amino Pyrimidine Compounds and Uses Thereof
|
|
EP2137165B1
(en)
*
|
2007-04-24 |
2013-04-24 |
Ingenium Pharmaceuticals GmbH |
Inhibitors of protein kinases
|
|
EP2200436B1
(en)
|
2007-09-04 |
2015-01-21 |
The Scripps Research Institute |
Substituted pyrimidinyl-amines as protein kinase inhibitors
|
|
BRPI0906799A2
(pt)
|
2008-01-11 |
2015-07-14 |
Hoffmann La Roche |
Moduladores para amiloide beta
|
|
KR101247840B1
(ko)
*
|
2008-02-22 |
2013-03-26 |
에프. 호프만-라 로슈 아게 |
아밀로이드 베타 조절제
|
|
MX2011003246A
(es)
|
2008-10-09 |
2011-04-21 |
Hoffmann La Roche |
Moduladores de beta amiloide.
|
|
KR101293421B1
(ko)
|
2008-11-10 |
2013-08-05 |
에프. 호프만-라 로슈 아게 |
헤테로사이클릭 감마 분비효소 조절제
|
|
MX2012004313A
(es)
*
|
2009-10-12 |
2012-07-20 |
Myrexis Inc |
Compuestos de amino-pirimidina como inhibidores de cinasa 1 de union a tank (tbk1) y/o i-kappa-b-cinasa epsilon (ikk epsilon).
|
|
WO2011075560A1
(en)
|
2009-12-17 |
2011-06-23 |
Merck Sharp & Dohme Corp. |
Aminopyrimidines as syk inhibitors
|
|
MA33926B1
(fr)
|
2009-12-17 |
2013-01-02 |
Merck Sharp & Dohme |
Aminopyrimidines en tant qu'inhibiteurs de la syk
|
|
US8486967B2
(en)
|
2010-02-17 |
2013-07-16 |
Hoffmann-La Roche Inc. |
Heteroaryl substituted piperidines
|
|
WO2012007500A2
(de)
|
2010-07-15 |
2012-01-19 |
Bayer Cropscience Ag |
Neue heterocyclische verbindungen als schädlingsbekämpfungsmittel
|
|
GB201012105D0
(en)
*
|
2010-07-19 |
2010-09-01 |
Domainex Ltd |
Novel pyrimidine compounds
|
|
US9376709B2
(en)
|
2010-07-26 |
2016-06-28 |
Biomatrica, Inc. |
Compositions for stabilizing DNA and RNA in blood and other biological samples during shipping and storage at ambient temperatures
|
|
WO2012018639A2
(en)
|
2010-07-26 |
2012-02-09 |
Biomatrica, Inc. |
Compositions for stabilizing dna, rna and proteins in saliva and other biological samples during shipping and storage at ambient temperatures
|
|
BR112013009823A2
(pt)
*
|
2010-10-22 |
2016-07-05 |
Bayer Ip Gmbh |
novos compostos heterocíclicos como pesticidas
|
|
US8754114B2
(en)
|
2010-12-22 |
2014-06-17 |
Incyte Corporation |
Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3
|
|
JP6085866B2
(ja)
|
2011-02-28 |
2017-03-01 |
アレイ バイオファーマ、インコーポレイテッド |
セリン/トレオニンキナーゼインヒビター
|
|
JP6147727B2
(ja)
|
2011-04-01 |
2017-06-14 |
ユニヴァーシティー オブ ユタ リサーチ ファウンデーション |
チロシン受容体キナーゼbtk阻害剤としての置換n−(3−(ピリミジン−4−イル)フェニル)アクリルアミド類似体
|
|
WO2012142329A1
(en)
*
|
2011-04-12 |
2012-10-18 |
Myrexis, Inc. |
Compositions and therapeutic uses of ikk-related kinase epsilon and tankbinding kinase 1 inhibitors
|
|
JP5912172B2
(ja)
|
2011-04-19 |
2016-04-27 |
バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH |
置換された4−アリール−n−フェニル−1,3,5−トリアジン−2−アミン
|
|
JP2014513687A
(ja)
|
2011-05-10 |
2014-06-05 |
メルク・シャープ・アンド・ドーム・コーポレーション |
Syk阻害薬としてのピリジルアミノピリジン
|
|
US9145391B2
(en)
|
2011-05-10 |
2015-09-29 |
Merck Sharp & Dohme Corp. |
Bipyridylaminopyridines as Syk inhibitors
|
|
WO2012154519A1
(en)
|
2011-05-10 |
2012-11-15 |
Merck Sharp & Dohme Corp. |
Aminopyrimidines as syk inhibitors
|
|
TWI555737B
(zh)
|
2011-05-24 |
2016-11-01 |
拜耳知識產權公司 |
含有硫醯亞胺基團之4-芳基-n-苯基-1,3,5-三氮雜苯-2-胺
|
|
KR20140045542A
(ko)
*
|
2011-07-12 |
2014-04-16 |
다우 아그로사이언시즈 엘엘씨 |
살충 조성물 및 그에 관한 방법
|
|
JP6097289B2
(ja)
|
2011-08-04 |
2017-03-15 |
アレイ バイオファーマ、インコーポレイテッド |
セリン/スレオニンキナーゼインヒビターとしてのキナゾリン化合物
|
|
DE102011112978A1
(de)
|
2011-09-09 |
2013-03-14 |
Merck Patent Gmbh |
Benzonitrilderivate
|
|
ES2587284T3
(es)
|
2011-09-16 |
2016-10-21 |
Bayer Intellectual Property Gmbh |
5-Fluoro-pirimidinas 2,4-disustituidas como inhibidores selectivos de CDK9
|
|
CN103930399B
(zh)
|
2011-09-16 |
2016-03-16 |
拜耳知识产权有限责任公司 |
包含亚氨基亚磺酰基的二取代的5-氟嘧啶衍生物
|
|
DK2820009T3
(en)
|
2012-03-01 |
2018-04-16 |
Array Biopharma Inc |
Serine / threonine kinase inhibitors
|
|
EP3495367B1
(en)
|
2012-06-13 |
2020-09-30 |
Incyte Holdings Corporation |
Substituted tricyclic compounds as fgfr inhibitors
|
|
US8809359B2
(en)
|
2012-06-29 |
2014-08-19 |
Ym Biosciences Australia Pty Ltd |
Phenyl amino pyrimidine bicyclic compounds and uses thereof
|
|
WO2014026125A1
(en)
|
2012-08-10 |
2014-02-13 |
Incyte Corporation |
Pyrazine derivatives as fgfr inhibitors
|
|
CA2882750A1
(en)
|
2012-08-27 |
2014-03-06 |
Jim Blake |
Serine/threonine kinase inhibitors for the treatment of hyperproliferative|diseases
|
|
JP6313772B2
(ja)
*
|
2012-10-04 |
2018-04-18 |
ユニヴァーシティー オブ ユタ リサーチ ファウンデーション |
チロシン受容体キナーゼbtk阻害剤である置換n−(3−(ピリミジン−4−イル)フェニル)アクリルアミド類似体
|
|
CA2887435A1
(en)
|
2012-10-04 |
2014-04-10 |
University Of Utah Research Foundation |
Substituted n-(3-(pyrimidin-4-yl)phenyl)acrylamide analogs as tyrosine receptor kinase btk inhibitors
|
|
CN104854091B
(zh)
|
2012-10-18 |
2018-04-03 |
拜耳药业股份公司 |
含砜基团的5‑氟‑n‑(吡啶‑2‑基)吡啶‑2‑胺衍生物
|
|
HK1213890A1
(zh)
|
2012-10-18 |
2016-07-15 |
Bayer Pharma Aktiengesellschaft |
含碸基团的4-(邻)-氟苯基-5-氟嘧啶-2-基胺
|
|
TW201418243A
(zh)
|
2012-11-15 |
2014-05-16 |
Bayer Pharma AG |
含有磺醯亞胺基團之n-(吡啶-2-基)嘧啶-4-胺衍生物
|
|
US9266892B2
(en)
|
2012-12-19 |
2016-02-23 |
Incyte Holdings Corporation |
Fused pyrazoles as FGFR inhibitors
|
|
WO2014100755A2
(en)
|
2012-12-20 |
2014-06-26 |
Biomatrica, Inc. |
Formulations and methods for stabilizing pcr reagents
|
|
GB201303109D0
(en)
*
|
2013-02-21 |
2013-04-10 |
Domainex Ltd |
Novel pyrimidine compounds
|
|
DK2986610T5
(en)
|
2013-04-19 |
2018-12-10 |
Incyte Holdings Corp |
BICYCLIC HETEROCYCLES AS FGFR INHIBITORS
|
|
EP3632208A1
(en)
|
2013-06-13 |
2020-04-08 |
Biomatrica, INC. |
Cell stabilization
|
|
EP3154338B1
(en)
|
2014-06-10 |
2020-01-29 |
Biomatrica, INC. |
Stabilization of thrombocytes at ambient temperatures
|
|
TW202134236A
(zh)
|
2014-06-12 |
2021-09-16 |
美商西爾拉癌症醫學公司 |
N-(氰基甲基)-4-(2-(4-𠰌啉基苯基胺基)嘧啶-4-基)苯甲醯胺
|
|
CA2964683A1
(en)
|
2014-10-16 |
2016-04-21 |
Bayer Pharma Aktiengesellschaft |
Fluorinated benzofuranyl-pyrimidine derivatives containing a sulfone group
|
|
US10851105B2
(en)
|
2014-10-22 |
2020-12-01 |
Incyte Corporation |
Bicyclic heterocycles as FGFR4 inhibitors
|
|
MA41551A
(fr)
|
2015-02-20 |
2017-12-26 |
Incyte Corp |
Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
|
|
WO2016134294A1
(en)
|
2015-02-20 |
2016-08-25 |
Incyte Corporation |
Bicyclic heterocycles as fgfr4 inhibitors
|
|
CR20170390A
(es)
|
2015-02-20 |
2017-10-23 |
Incyte Holdings Corp |
Heterociclos biciclicos como inhibidores de fgfr
|
|
WO2016150902A1
(en)
|
2015-03-24 |
2016-09-29 |
Bayer Pharma Aktiengesellschaft |
Use of 4-(4-fluoro-2-methoxyphenyl)-n-{3-[(s-methylsulfonimidoyl)methyl]phenyl}-1,3,5-triazin-2-amine for treating gastric cancers
|
|
CN107427520A
(zh)
|
2015-03-24 |
2017-12-01 |
拜耳医药股份有限公司 |
4‑(4‑氟‑2‑甲氧基苯基)‑n‑{3‑[(s‑甲基磺酰亚氨基)甲基]苯基}‑1,3,5‑三嗪‑2‑胺用于治疗淋巴瘤的用途
|
|
WO2016150893A1
(en)
|
2015-03-24 |
2016-09-29 |
Bayer Pharma Aktiengesellschaft |
Use of 4-(4-fluoro-2-methoxyphenyl)-n-{3-[(s-methylsulfonimidoyl)methyl]phenyl}-1,3,5-triazin-2-amine for treating multiple myeloma
|
|
US20180194769A1
(en)
|
2015-07-06 |
2018-07-12 |
Rodin Therapeutics, Inc. |
Hetero-halo inhibitors of histone deacetylase
|
|
EP3319968A1
(en)
|
2015-07-06 |
2018-05-16 |
Rodin Therapeutics, Inc. |
Heterobicyclic n-aminophenyl-amides as inhibitors of histone deacetylase
|
|
EP3356373B1
(en)
|
2015-09-29 |
2020-02-19 |
Bayer Pharma Aktiengesellschaft |
Novel macrocyclic sulfondiimine compounds
|
|
CN108368129B
(zh)
|
2015-10-08 |
2021-08-17 |
拜耳医药股份有限公司 |
改性大环化合物
|
|
WO2017060322A2
(en)
|
2015-10-10 |
2017-04-13 |
Bayer Pharma Aktiengesellschaft |
Ptefb-inhibitor-adc
|
|
RU2695133C1
(ru)
|
2015-10-12 |
2019-07-22 |
Чонг Кун Данг Фармасьютикал Корп. |
Производные оксадиазоламина в качестве ингибитора гистондеацетилазы 6 и содержащая их фармацевтическая композиция
|
|
KR102787387B1
(ko)
|
2015-12-08 |
2025-03-26 |
바이오매트리카 인코포레이티드 |
적혈구 침강 속도의 감소
|
|
CN110818690B
(zh)
|
2016-07-26 |
2021-08-10 |
深圳市塔吉瑞生物医药有限公司 |
用于抑制蛋白酪氨酸激酶活性的氨基嘧啶类化合物
|
|
US20190231751A1
(en)
*
|
2016-09-12 |
2019-08-01 |
Imago Pharmaceuticals, Inc. |
Treatment of fibrotic disorders with jun n-terminal kinase inhibitors
|
|
JP6756925B2
(ja)
|
2017-01-11 |
2020-09-16 |
ロダン・セラピューティクス,インコーポレーテッド |
ヒストンデアセチラーゼの二環式阻害剤
|
|
WO2018152223A1
(en)
*
|
2017-02-15 |
2018-08-23 |
University Of Massachusetts |
Methods of treating angiogenesis-related disorders using jnk3 inhibitors
|
|
GB201702947D0
(en)
|
2017-02-23 |
2017-04-12 |
Domainex Ltd |
Novel compounds
|
|
US11254690B2
(en)
|
2017-03-28 |
2022-02-22 |
Bayer Pharma Aktiengesellschaft |
PTEFb inhibiting macrocyclic compounds
|
|
CA3057891A1
(en)
|
2017-03-28 |
2018-10-04 |
Bayer Aktiengesellschaft |
Novel ptefb inhibiting macrocyclic compounds
|
|
GB201705263D0
(en)
*
|
2017-03-31 |
2017-05-17 |
Probiodrug Ag |
Novel inhibitors
|
|
AR111960A1
(es)
|
2017-05-26 |
2019-09-04 |
Incyte Corp |
Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
|
|
SMT202200232T1
(it)
|
2017-08-07 |
2022-07-21 |
Alkermes Inc |
Inibitori biciclici di istone deacetilasi
|
|
TWI802605B
(zh)
*
|
2017-10-17 |
2023-05-21 |
德商默克專利有限公司 |
嘧啶TBK/IKKε抑制劑化合物及其用途
|
|
WO2019079373A1
(en)
*
|
2017-10-17 |
2019-04-25 |
Merck Patent Gmbh |
PYRIMIDINE TBK / IKKε INHIBITORY COMPOUNDS AND USES THEREOF
|
|
EP3732285A1
(en)
|
2017-12-28 |
2020-11-04 |
Tract Pharmaceuticals, Inc. |
Stem cell culture systems for columnar epithelial stem cells, and uses related thereto
|
|
MA51820A
(fr)
|
2018-02-13 |
2021-05-19 |
Bayer Ag |
Utilisation de 5-fluoro-4-(4-fluoro-2-méthoxyphényl)-n-(4-[(s-méthylsulfonimidoyl)méthyl]pyridin-2-yl)pyridin-2-amine pour traiter un lymphome diffus à grandes cellules b
|
|
CN112566912A
(zh)
|
2018-05-04 |
2021-03-26 |
因赛特公司 |
Fgfr抑制剂的盐
|
|
US11466004B2
(en)
|
2018-05-04 |
2022-10-11 |
Incyte Corporation |
Solid forms of an FGFR inhibitor and processes for preparing the same
|
|
WO2020068846A1
(en)
*
|
2018-09-25 |
2020-04-02 |
Heterocyclic Compound |
Heterocyclic compound
|
|
TWI850262B
(zh)
*
|
2018-09-25 |
2024-08-01 |
美商卡都瑞恩醫藥公司 |
胺基嘧啶化合物
|
|
AR117487A1
(es)
*
|
2018-12-21 |
2021-08-11 |
Bayer Ag |
1,3,4-oxadiazoles y derivados de éstos como agentes fungicidas
|
|
WO2020185532A1
(en)
|
2019-03-08 |
2020-09-17 |
Incyte Corporation |
Methods of treating cancer with an fgfr inhibitor
|
|
US11591329B2
(en)
|
2019-07-09 |
2023-02-28 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
WO2021050700A1
(en)
*
|
2019-09-13 |
2021-03-18 |
The Broad Institute, Inc. |
Cyclooxygenase-2 inhibitors and uses thereof
|
|
US12122767B2
(en)
|
2019-10-01 |
2024-10-22 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
GEAP202415945A
(en)
|
2019-10-14 |
2024-04-25 |
Incyte Corp |
Bicyclic heterocycles as fgfr inhibitors
|
|
WO2021076728A1
(en)
|
2019-10-16 |
2021-04-22 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
BR112022010664A2
(pt)
|
2019-12-04 |
2022-08-16 |
Incyte Corp |
Derivados de um inibidor de fgfr
|
|
EP4069696A1
(en)
|
2019-12-04 |
2022-10-12 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
US12012409B2
(en)
|
2020-01-15 |
2024-06-18 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
JP7587113B2
(ja)
*
|
2020-09-29 |
2024-11-20 |
日亜化学工業株式会社 |
異方性磁性粉末の製造方法および異方性磁性粉末
|
|
TW202304459A
(zh)
|
2021-04-12 |
2023-02-01 |
美商英塞特公司 |
包含fgfr抑制劑及nectin-4靶向劑之組合療法
|
|
JP2024522189A
(ja)
|
2021-06-09 |
2024-06-11 |
インサイト・コーポレイション |
Fgfr阻害剤としての三環式ヘテロ環
|
|
WO2022261159A1
(en)
|
2021-06-09 |
2022-12-15 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
WO2023107705A1
(en)
|
2021-12-10 |
2023-06-15 |
Incyte Corporation |
Bicyclic amines as cdk12 inhibitors
|