JP2010535704A5 - - Google Patents

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Publication number
JP2010535704A5
JP2010535704A5 JP2010504096A JP2010504096A JP2010535704A5 JP 2010535704 A5 JP2010535704 A5 JP 2010535704A5 JP 2010504096 A JP2010504096 A JP 2010504096A JP 2010504096 A JP2010504096 A JP 2010504096A JP 2010535704 A5 JP2010535704 A5 JP 2010535704A5
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JP
Japan
Prior art keywords
group
atom
halogen atom
hydroxy
lower alkyl
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JP2010504096A
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English (en)
Japanese (ja)
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JP5292390B2 (ja
JP2010535704A (ja
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Priority to JP2010504096A priority Critical patent/JP5292390B2/ja
Priority claimed from JP2010504096A external-priority patent/JP5292390B2/ja
Publication of JP2010535704A publication Critical patent/JP2010535704A/ja
Publication of JP2010535704A5 publication Critical patent/JP2010535704A5/ja
Application granted granted Critical
Publication of JP5292390B2 publication Critical patent/JP5292390B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2010504096A 2007-08-07 2008-08-06 アンドロゲン受容体調節剤としてのピロリジン−２−オン誘導体 Expired - Fee Related JP5292390B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2010504096A JP5292390B2 (ja) 2007-08-07 2008-08-06 アンドロゲン受容体調節剤としてのピロリジン−２−オン誘導体

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP2007205966 2007-08-07
JP2007205966 2007-08-07
JP2007299658 2007-11-19
JP2007299658 2007-11-19
JP2010504096A JP5292390B2 (ja) 2007-08-07 2008-08-06 アンドロゲン受容体調節剤としてのピロリジン−２−オン誘導体
PCT/JP2008/064500 WO2009020234A2 (en) 2007-08-07 2008-08-06 Pyrrolidin-2 -one derivatives as androgen receptor modulator

Publications (3)

Publication Number Publication Date
JP2010535704A JP2010535704A (ja) 2010-11-25
JP2010535704A5 true JP2010535704A5 (enExample) 2011-09-22
JP5292390B2 JP5292390B2 (ja) 2013-09-18

Family

ID=40329363

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010504096A Expired - Fee Related JP5292390B2 (ja) 2007-08-07 2008-08-06 アンドロゲン受容体調節剤としてのピロリジン−２−オン誘導体

Country Status (34)

Country Link
US (2) US7834051B2 (enExample)
EP (1) EP2176220B1 (enExample)
JP (1) JP5292390B2 (enExample)
KR (1) KR20100049644A (enExample)
CN (1) CN101821235B (enExample)
AR (1) AR067823A1 (enExample)
AU (1) AU2008284662B2 (enExample)
BR (1) BRPI0814957B8 (enExample)
CA (1) CA2695852C (enExample)
CL (1) CL2008002313A1 (enExample)
CO (1) CO6160326A2 (enExample)
CR (1) CR11266A (enExample)
CY (1) CY1114067T1 (enExample)
DK (1) DK2176220T3 (enExample)
DO (1) DOP2010000053A (enExample)
EA (1) EA017429B1 (enExample)
ES (1) ES2406685T3 (enExample)
GE (1) GEP20125571B (enExample)
HR (1) HRP20130374T1 (enExample)
JO (1) JO2864B1 (enExample)
MA (1) MA31639B1 (enExample)
ME (1) ME01579B (enExample)
MX (1) MX2010001484A (enExample)
MY (1) MY159910A (enExample)
NZ (1) NZ583624A (enExample)
PE (1) PE20090899A1 (enExample)
PL (1) PL2176220T3 (enExample)
PT (1) PT2176220E (enExample)
RS (1) RS52812B (enExample)
SI (1) SI2176220T1 (enExample)
TN (1) TN2010000062A1 (enExample)
TW (1) TWI418543B (enExample)
WO (1) WO2009020234A2 (enExample)
ZA (1) ZA201001289B (enExample)

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EA017429B1 (ru) * 2007-08-07 2012-12-28 Такеда Фармасьютикал Компани Лимитед Циклические аминные соединения
US8268872B2 (en) * 2008-02-22 2012-09-18 Radius Health, Inc. Selective androgen receptor modulators
MX2010009162A (es) 2008-02-22 2010-12-21 Radius Health Inc Moduladores selectivos del receptor de androgeno.
AR071069A1 (es) * 2008-03-26 2010-05-26 Takeda Pharmaceutical Derivados sustituidos de pirazol y su uso para la prevencion o el tratamiento de cancer
EP2531029B1 (en) 2010-02-04 2016-10-19 Radius Health, Inc. Selective androgen receptor modulators
WO2011143469A1 (en) 2010-05-12 2011-11-17 Radius Health,Inc Therapeutic regimens
US8642632B2 (en) 2010-07-02 2014-02-04 Radius Health, Inc. Selective androgen receptor modulators
BR112013007685B1 (pt) 2010-09-28 2021-11-09 Radius Pharmaceuticals, Inc Compostos moduladores de receptor andrógeno seletivos, composição farmacêutica compreendendo os referidos compostos, método de identificação de um composto capaz de modular um receptor andrógeno, usos de um composto ou da composição e processo para a preparação de um composto
US20150057452A1 (en) * 2012-04-04 2015-02-26 Catylix, Inc. Selective androgen receptor modulators
CN104768544B (zh) 2012-08-09 2017-06-16 迪纳米斯治疗公司 包括葡甲胺或其盐的组合物在制备减少或预防甘油三酯水平增加的药物中的应用
JP6338583B2 (ja) * 2012-09-21 2018-06-06 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ Ｃ−ｃ三重結合を有する化合物およびそれらの液晶混合物における使用。
US9421264B2 (en) 2014-03-28 2016-08-23 Duke University Method of treating cancer using selective estrogen receptor modulators
FI3834824T3 (fi) 2014-03-28 2025-12-05 Univ Duke Estrogeenireseptoripositiivisen rintasyövän hoito selektiivisellä estrogeenireseptorin modulaattorilla
KR101597327B1 (ko) 2014-04-24 2016-02-24 동아에스티 주식회사 옥사졸리딘계 화합물 및 이를 포함하는 선택적 안드로겐 수용체 효능제
CN103951688B (zh) * 2014-05-06 2016-04-20 成都安斯利生物医药有限公司 一种制备3,5-二氟-4-甲基苯硼酸的方法
JP7221699B2 (ja) 2016-06-22 2023-02-14 エリプセス ファーマ エルティーディー Ａｒ＋乳癌の治療方法
KR102881465B1 (ko) 2017-01-05 2025-11-04 래디어스 파마슈티컬스, 인코포레이티드 Rad1901-2hcl의 다형 형태
SG11202013177WA (en) 2018-07-04 2021-01-28 Radius Pharmaceuticals Inc Polymorphic forms of rad 1901-2hcl
EP3908581A1 (en) 2019-01-11 2021-11-17 Grünenthal GmbH Substituted pyrrolidine amides iii
KR20210127961A (ko) 2019-02-12 2021-10-25 래디어스 파마슈티컬스, 인코포레이티드 방법 및 화합물
CN110204505B (zh) * 2019-05-31 2023-02-03 荆门医药工业技术研究院 (s)-3-苄氧羰基-4-异丙基-2,5-恶唑烷二酮的制备工艺
US20230012570A1 (en) * 2019-11-20 2023-01-19 Medshine Discovery Inc. Bicyclic compound used as selective androgen receptor modulator

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US6258833B1 (en) 1999-12-23 2001-07-10 Icos Corporation Cyclic AMP-specific phosphodiesterase inhibitors
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JP2002088073A (ja) * 2000-09-08 2002-03-27 Yamanouchi Pharmaceut Co Ltd 抗アンドロゲン剤
FR2817472B1 (fr) 2000-12-06 2003-01-03 Oreal Composition de teinture d'oxydation a base de 1-(4-aminophenyl)pyrrolidines substituees au moins en position 2 et 3 et procede de teinture de mise en oeuvre
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AU2005251781C1 (en) 2004-06-07 2008-02-21 University Of Tennessee Research Foundation Selective androgen receptor modulators and methods of use thereof
KR20070112775A (ko) 2005-01-10 2007-11-27 아카디아 파마슈티칼스 인코포레이티드 선택적인 안드로겐 수용체 조절자로서의 아미노페닐 유도체
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JP5089578B2 (ja) 2005-05-13 2012-12-05 イーライ リリー アンド カンパニー 選択的なアンドロゲン受容体調節物質としての置換型ｎ−アリールピロリジン
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US20090042857A1 (en) 2006-02-20 2009-02-12 Masuo Yamaoka Novel Pharmaceutical
MX2009000714A (es) 2006-07-19 2009-07-27 Osurf Moduladores de receptor de androgeno selectivos, analogos y derivados de los mismos.
CA2658558A1 (en) 2006-07-26 2008-01-31 Novartis Ag Inhibitors of undecaprenyl pyrophosphate synthase
WO2008066117A1 (en) 2006-11-30 2008-06-05 Takeda Pharmaceutical Company Limited Cyclic amine compound
EA017429B1 (ru) 2007-08-07 2012-12-28 Такеда Фармасьютикал Компани Лимитед Циклические аминные соединения

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